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  1. Article ; Online: Reply to comment on "Unexpected decline in glycated hemoglobin level after emergency COVID-19 measures in three robust older Japanese women with prediabetes/mild type 2 diabetes".

    Okuno, Tazuo / Iritani, Osamu / Kodera, Kumie / Hama, Daisuke / Kane, Asami / Morigaki, Kozue / Terai, Toshio / Maeno, Norie / Morimoto, Shigeto

    Geriatrics & gerontology international

    2022  Volume 22, Issue 7, Page(s) 541–542

    MeSH term(s) Blood Glucose ; COVID-19 ; Diabetes Mellitus, Type 2/diagnosis ; Female ; Glycated Hemoglobin A/analysis ; Humans ; Japan ; Prediabetic State/diagnosis
    Chemical Substances Blood Glucose ; Glycated Hemoglobin A
    Language English
    Publishing date 2022-05-13
    Publishing country Japan
    Document type Letter ; Comment
    ZDB-ID 2113849-7
    ISSN 1447-0594 ; 1444-1586
    ISSN (online) 1447-0594
    ISSN 1444-1586
    DOI 10.1111/ggi.14396
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  2. Article ; Online: Unexpected decline in glycated hemoglobin level after emergency COVID-19 measures in three robust older Japanese women with prediabetes/mild type-2 diabetes.

    Okuno, Tazuo / Iritani, Osamu / Kodera, Kumie / Hama, Daisuke / Kane, Asami / Morigaki, Kozue / Terai, Toshio / Maeno, Norie / Morimoto, Shigeto

    Geriatrics & gerontology international

    2022  Volume 22, Issue 5, Page(s) 457–458

    MeSH term(s) Blood Glucose ; COVID-19 ; Diabetes Mellitus, Type 2/complications ; Diabetes Mellitus, Type 2/diagnosis ; Female ; Glycated Hemoglobin A/analysis ; Humans ; Japan ; Prediabetic State/diagnosis
    Chemical Substances Blood Glucose ; Glycated Hemoglobin A
    Language English
    Publishing date 2022-03-23
    Publishing country Japan
    Document type Letter
    ZDB-ID 2113849-7
    ISSN 1447-0594 ; 1444-1586
    ISSN (online) 1447-0594
    ISSN 1444-1586
    DOI 10.1111/ggi.14377
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  3. Article ; Online: Work-related experiences of people living with young-onset dementia in Japan.

    Ikeuchi, Satomi / Omote, Shizuko / Tanaka, Koji / Okamoto, Rie / Morikawa, Yuko / Iritani, Osamu

    Health & social care in the community

    2020  Volume 30, Issue 2, Page(s) 548–557

    Abstract: Dementia that occurs before age 65 years is defined as young-onset dementia (YOD). YOD develops during the prime of a person's working life and has a major impact on not only work but life in general. Therefore, Japan is promoting measures to support ... ...

    Abstract Dementia that occurs before age 65 years is defined as young-onset dementia (YOD). YOD develops during the prime of a person's working life and has a major impact on not only work but life in general. Therefore, Japan is promoting measures to support work and social participation, taking into account the characteristics of people living with YOD. Given the rarity of YOD, few studies have examined the difficulties faced by people living with YOD during this life stage or the kinds of support they require. We believe that studying these difficulties and support requirements will contribute to prolonging the careers of people living with YOD and to providing them support during social, emotional and economic crises. This qualitative study aims to clarify the experiences of working-age Japanese people living with YOD to examine, from their perspective, possibilities for employment support. For this study, people living with YOD who were currently working were recruited by snowball sampling. This study was conducted in Japan between September 2018 and February 2019. A semi-structured interview was conducted, and the contents were transcribed and analysed using Colaizzi's qualitative methodology. Four categories were derived: (a) crisis from continuing to work, (b) seeking support, (c) overcoming challenges to work and (d) reaffirming a sense of purpose by resuming work and social participation. Participants were able to continue working and socialising by letting others know about their illness and seeking support. In the process of reaffirming a sense of purpose by resuming work and social participation, participants continued working or transitioned to socially active lives after leaving their job thanks to the support of work colleagues and medical and healthcare/welfare professionals who understand YOD. The results indicate a need for awareness raising in the workplace to promote understanding of such professional support and its significance.
    MeSH term(s) Aged ; Dementia/epidemiology ; Dementia/psychology ; Health Personnel ; Humans ; Japan ; Qualitative Research ; Social Participation
    Language English
    Publishing date 2020-09-06
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1155902-0
    ISSN 1365-2524 ; 0966-0410
    ISSN (online) 1365-2524
    ISSN 0966-0410
    DOI 10.1111/hsc.13157
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  4. Article ; Online: Sarcopenia and decline in appendicular skeletal muscle mass are associated with hypoperfusion in key hubs of central autonomic network on 3DSRT in older adults with progression of normal cognition to Alzheimer's disease.

    Demura, Taichi / Okuno, Tazuo / Miwa, Takaki / Iritani, Osamu / Nakano, Hiroyuki / Yamamoto, Junpei / Shiga, Hideaki / Kodera, Kumie / Morimoto, Chihiro / Demura, Noboru / Morimoto, Shigeto

    Geriatrics & gerontology international

    2022  Volume 23, Issue 1, Page(s) 16–24

    Abstract: Aim: Although sarcopenia is common in patients with Alzheimer's disease (AD), the neural substrates involved remain unclear. We investigated the relationship between sarcopenia, as well as its definition components, and regional cerebral blood flow ( ... ...

    Abstract Aim: Although sarcopenia is common in patients with Alzheimer's disease (AD), the neural substrates involved remain unclear. We investigated the relationship between sarcopenia, as well as its definition components, and regional cerebral blood flow (rCBF) in older adults with progression of normal cognition to AD.
    Methods: 99m
    Results: Logistic regression analysis adjusted by age, sex, mini-mental state examination score and education showed that sarcopenia as well as ASMI less than the cut-off (men 7.0 kg/m
    Conclusions: Hypoperfusion in key hubs of central autonomic network is implicated in the emergence of sarcopenia, probably through ASMI decline in vulnerable older adults. Geriatr Gerontol Int 2023; 23: 16-24.
    MeSH term(s) Male ; Humans ; Female ; Aged ; Aged, 80 and over ; Sarcopenia/diagnostic imaging ; Alzheimer Disease/diagnosis ; Cognition ; Frontal Lobe ; Muscle, Skeletal/diagnostic imaging
    Language English
    Publishing date 2022-12-16
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 2113849-7
    ISSN 1447-0594 ; 1444-1586
    ISSN (online) 1447-0594
    ISSN 1444-1586
    DOI 10.1111/ggi.14515
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  5. Article: Correction to: Relationship Between Blood Pressure Levels on Admission and the Onset of Acute Pneumonia in Elderly Patients With Cerebral Hemorrhage.

    Ishisaka, Taishi / Igarashi, Yuta / Kodera, Kumie / Okuno, Tazuo / Morita, Takuro / Himeno, Taroh / Hamada, Kazu / Yano, Hiroshi / Higashikawa, Toshihiro / Iritani, Osamu / Iwai, Kunimitsu / Morimoto, Shigeto / Okuro, Masashi

    Journal of clinical medicine research

    2021  Volume 13, Issue 1, Page(s) 73

    Abstract: This corrects the article DOI: 10.14740/jocmr4330.]. ...

    Abstract [This corrects the article DOI: 10.14740/jocmr4330.].
    Language English
    Publishing date 2021-01-12
    Publishing country Canada
    Document type Published Erratum
    ZDB-ID 2548987-2
    ISSN 1918-3011 ; 1918-3003
    ISSN (online) 1918-3011
    ISSN 1918-3003
    DOI 10.14740/jocmr4330c1
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  6. Article ; Online: Transient obstruction of the transverse colon caused by percutaneous endoscopic gastrostomy: A case report.

    Hamada, Kazu / Tateishi, Junnosuke / Sugiki, Shigeru / Ishisaka, Taishi / Igarashi, Yuta / Kodera, Kumie / Okuno, Tazuo / Morita, Takuro / Himeno, Tarou / Yano, Hiroshi / Higashikawa, Toshihiro / Iritani, Osamu / Iwai, Kunimitsu / Morimoto, Shigeto / Okuro, Masashi

    Geriatrics & gerontology international

    2021  Volume 21, Issue 9, Page(s) 865–866

    MeSH term(s) Colon, Transverse/diagnostic imaging ; Colon, Transverse/surgery ; Gastrostomy/adverse effects ; Humans
    Language English
    Publishing date 2021-07-11
    Publishing country Japan
    Document type Case Reports ; Letter
    ZDB-ID 2113849-7
    ISSN 1447-0594 ; 1444-1586
    ISSN (online) 1447-0594
    ISSN 1444-1586
    DOI 10.1111/ggi.14226
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  7. Article ; Online: Clusters of COVID-19 in long-term care hospitals and facilities in Japan from 16 January to 9 May 2020.

    Iritani, Osamu / Okuno, Tazuo / Hama, Daisuke / Kane, Asami / Kodera, Kumie / Morigaki, Kozue / Terai, Toshio / Maeno, Norie / Morimoto, Shigeto

    Geriatrics & gerontology international

    2020  Volume 20, Issue 7, Page(s) 715–719

    Abstract: Aim: To clarify the association of cluster number and size of coronavirus disease 2019 (COVID-19) in long-term care (LTC) hospitals/facilities, general medical/welfare facilities and non-medical/welfare facilities with morbidity and mortality in 47 ... ...

    Abstract Aim: To clarify the association of cluster number and size of coronavirus disease 2019 (COVID-19) in long-term care (LTC) hospitals/facilities, general medical/welfare facilities and non-medical/welfare facilities with morbidity and mortality in 47 prefectures during 16 January to 9 May 2020 in Japan.
    Methods: Information on COVID-19 clusters (n ≥2), and morbidity and mortality of COVID-19 was collected.
    Results: A total of 381 clusters with 3786 infected cases were collected, accounting for 23.9% of 15 852 cumulated cases on 9 May 2020. Although the cluster number (/10
    Conclusions: Preventive efforts against COVID-19 outbreaks even at the early phase of the epidemic are critically important in LTC hospitals/facilities, as both the larger number and size of clusters only in LTC hospitals/facilities were independently linked to higher mortality in prefectures in Japan. Geriatr Gerontol Int 2020; 20: 715-719.
    MeSH term(s) Aged ; Betacoronavirus/isolation & purification ; COVID-19 ; Cluster Analysis ; Coronavirus Infections/mortality ; Coronavirus Infections/prevention & control ; Female ; Hospitals, Chronic Disease/statistics & numerical data ; Humans ; Infection Control/organization & administration ; Japan/epidemiology ; Long-Term Care/methods ; Long-Term Care/organization & administration ; Long-Term Care/trends ; Male ; Mortality ; Pandemics/prevention & control ; Pneumonia, Viral/mortality ; Pneumonia, Viral/prevention & control ; SARS-CoV-2 ; Skilled Nursing Facilities/statistics & numerical data
    Keywords covid19
    Language English
    Publishing date 2020-07-07
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 2113849-7
    ISSN 1447-0594 ; 1444-1586
    ISSN (online) 1447-0594
    ISSN 1444-1586
    DOI 10.1111/ggi.13973
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  8. Article: Metabolic changes in the plasma of mild Alzheimer's disease patients treated with Hachimijiogan.

    Kainuma, Mosaburo / Kawakatsu, Shinobu / Kim, Jun-Dal / Ouma, Shinji / Iritani, Osamu / Yamashita, Ken-Ichiro / Ohara, Tomoyuki / Hirano, Shigeki / Suda, Shiro / Hamano, Tadanori / Hieda, Sotaro / Yasui, Masaaki / Yoshiiwa, Aoi / Shiota, Seiji / Hironishi, Masaya / Wada-Isoe, Kenji / Sasabayashi, Daiki / Yamasaki, Sho / Murata, Masayuki /
    Funakoshi, Kouta / Hayashi, Kouji / Shirafuji, Norimichi / Sasaki, Hirohito / Kajimoto, Yoshinori / Mori, Yukiko / Suzuki, Michio / Ito, Hidefumi / Ono, Kenjiro / Tsuboi, Yoshio

    Frontiers in pharmacology

    2023  Volume 14, Page(s) 1203349

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2023-06-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2023.1203349
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  9. Article ; Online: Orthogeriatric co-management at a regional core hospital as a new multidisciplinary approach in Japanese hip fracture operation.

    Higashikawa, Toshihiro / Shigemoto, Kenji / Moriyama, Manabu / Usuda, Daisuke / Hangyou, Masahiro / Inujima, Hiromi / Nozaki, Kakeru / Yamaguchi, Miyako / Usuda, Kimiko / Iritani, Osamu / Morimoro, Shigeto / Horii, Takeshi / Nakahashi, Takeshi / Matsumoto, Tadami / Hirohisa, Toga / Takashima, Shigeki / Kanda, Tsugiyasu / Okuro, Masashi / Sawaguchi, Takeshi

    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association

    2022  Volume 29, Issue 1, Page(s) 273–277

    Abstract: Background: This study aimed to evaluate the effects of orthogeriatric co-management of hip fractures at a regional core hospital.: Methods: This study included patients with proximal hip fracture. Patients were divided into two groups, conventional ... ...

    Abstract Background: This study aimed to evaluate the effects of orthogeriatric co-management of hip fractures at a regional core hospital.
    Methods: This study included patients with proximal hip fracture. Patients were divided into two groups, conventional multidisciplinary group I including patients attending the hospital between April 2015 and March 2016 and orthogeriatric group II including patients attending the hospital between April 2016 and March 2017, which were compared retrospectively. In the control group, the conventional multidisciplinary team treated patients as whole-body controls. In the intervention group, the newly recruited geriatricians performed physical examinations, laboratory tests, radioactive imaging, and physiological tests. Furthermore, they consulted ward pharmacists, rigorously conducted positive polypharmacy interventions , and evaluated the type and number of mediated drugs on admission.
    Results: The number of medicated drugs significantly decreased from 6.03 ± 4.3 on admission to 5.50 ± 3.59 on discharge in group II, whereas group I did not show a significant decrease. Despite the more number of hospitalized patients in group II (166 patients) than in group I (126 patients), the recovery rate from postoperative urinary retention increased significantly from 57.8% (19/30) in group I to 84.3% (32/59) in group II (p = 0.049), while the incidence of aspiration pneumonia decreased from 7.1% (9/126) in group I to 2.49% (4/166) in group II (p = 0.08). The patients received six or more prescribed drugs on admission, and the number remained constant. However, the number of medicated drugs on discharge showed a marginally significant decrease from 6.03 ± 4.3 in group I to 5.50 ± 3.59 in group II (p < 0.05).
    Conclusions: Compared to the conventional multidisciplinary group, the orthogeriatric team contributed to reducing the number of multi-effect drugs and perioperative complications without negatively affecting mortality despite the increased number of patients. The in-hospital mortality rate did not change between the groups. The orthogeriatric program succeeded in preventing and treating perioperative complications.
    MeSH term(s) Humans ; Aged ; Retrospective Studies ; Japan/epidemiology ; Health Services for the Aged ; Hip Fractures ; Hospitals
    Language English
    Publishing date 2022-11-26
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 1314243-4
    ISSN 1436-2023 ; 0949-2658
    ISSN (online) 1436-2023
    ISSN 0949-2658
    DOI 10.1016/j.jos.2022.11.002
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    Zs.A 4484: Show issues Location:
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  10. Article ; Online: Association of olfactory impairment with indexes of sarcopenia and frailty in community-dwelling older adults.

    Harita, Masayuki / Miwa, Takaki / Shiga, Hideaki / Yamada, Kentaro / Sugiyama, Eriko / Okabe, Yuki / Miyake, Yuko / Okuno, Tazuo / Iritani, Osamu / Morimoto, Shigeto

    Geriatrics & gerontology international

    2019  Volume 19, Issue 5, Page(s) 384–391

    Abstract: Aim: Individuals with olfactory or gustatory impairment often have associated difficulties with food-related activities. As both functions decline in older adults, we investigated the association of these impairments with sarcopenia/frailty indexes in ... ...

    Abstract Aim: Individuals with olfactory or gustatory impairment often have associated difficulties with food-related activities. As both functions decline in older adults, we investigated the association of these impairments with sarcopenia/frailty indexes in community-dwelling older adults.
    Methods: A total of 141 participants (69 men and 72 women, mean age 73.0 years) were enrolled. Odor identification was examined using the Open Essence test. Salty and sweet tastes were assessed using a whole-mouth gustatory test. Participants underwent evaluation of the appendicular skeletal muscle mass index (ASMI) by InBody720 and grip strength, and determination of the Study of Osteoporotic Fractures frailty index.
    Results: Participants with olfactory impairment (Open Essence ≤7), but not with gustatory impairment, showed a significantly higher prevalence of ASMI and grip strength less than the cut-off values recommended by the Asian Working Group for Sarcopenia, and Study of Osteoporotic Fractures frailty and/or pre-frailty status, compared with those without impairment. Multivariate logistic regression analysis showed a significant association of olfactory impairment with ASMI less than the cut-off value, grip strength less than the cut-off value, Asian Working Group for Sarcopenia sarcopenia and pre-frailty/frailty in the Study of Osteoporotic Fractures index in the whole population, and with ASMI less than the cut-off value and Asian Working Group for Sarcopenia sarcopenia in women, after adjustment. Three (Japanese cypress, wood and roasted garlic) and four (Japanese orange, India ink, menthol and curry) Open Essence odorants were elucidated as the "sarcopenia subset" and "frailty subset," respectively, and showed higher ability to identify sarcopenia and frailty status, compared with the remaining five odorants.
    Conclusions: These findings suggest that olfactory impairment is closely associated with sarcopenia and/or frailty in community-dwelling older adults. Geriatr Gerontol Int 2019; 19: 384-391.
    MeSH term(s) Aged ; Agnosia/diagnosis ; Agnosia/epidemiology ; Agnosia/physiopathology ; Body Mass Index ; Correlation of Data ; Female ; Frailty/diagnosis ; Frailty/epidemiology ; Frailty/physiopathology ; Geriatric Assessment/methods ; Humans ; Independent Living/statistics & numerical data ; Japan/epidemiology ; Male ; Muscle Strength ; Muscle, Skeletal/pathology ; Muscle, Skeletal/physiopathology ; Prevalence ; Sarcopenia/diagnosis ; Sarcopenia/epidemiology ; Sarcopenia/physiopathology ; Taste
    Language English
    Publishing date 2019-04-09
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 2113849-7
    ISSN 1447-0594 ; 1444-1586
    ISSN (online) 1447-0594
    ISSN 1444-1586
    DOI 10.1111/ggi.13621
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