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  1. Article ; Online: Postoperative nausea and vomiting: is the big little problem becoming a smaller little problem?

    Benhamou, Dan

    British journal of anaesthesia

    2023  Volume 131, Issue 1, Page(s) 22–25

    Abstract: Postoperative nausea and vomiting (PONV) has been identified as a big (very frequently encountered) little (not linked to life-threatening outcomes) problem. Traditional drugs (dexamethasone, droperidol or similar drugs, serotonin receptor antagonists) ... ...

    Abstract Postoperative nausea and vomiting (PONV) has been identified as a big (very frequently encountered) little (not linked to life-threatening outcomes) problem. Traditional drugs (dexamethasone, droperidol or similar drugs, serotonin receptor antagonists) each have significant but limited effect, leading to an increasing use of combination therapies. High-risk patients, often identified through use of risk scoring systems, remain with a significant residual risk despite combining up to three traditional drugs. A recent correspondence in this Journal proposes the use of up to five anti-emetic drugs to further minimise the risk. This disruptive strategy was supported by favourable initial results, absence of side-effects and lower acquisition costs of the added new drugs (aprepitant and palonosetron) because of their recent loss of patent protection. These results are provocative and hypothesis generating, but need confirmation and do not warrant immediate changes in clinical practice. The next steps will also necessitate wider implementation of protocols protecting patients from PONV and a search for additional drugs and techniques aimed at treating established PONV.
    MeSH term(s) Humans ; Postoperative Nausea and Vomiting/prevention & control ; Postoperative Nausea and Vomiting/chemically induced ; Antiemetics/therapeutic use ; Droperidol/therapeutic use ; Serotonin Antagonists/therapeutic use ; Risk Factors ; Vomiting/chemically induced ; Dexamethasone/therapeutic use ; Drug Therapy, Combination
    Chemical Substances Antiemetics ; Droperidol (O9U0F09D5X) ; Serotonin Antagonists ; Dexamethasone (7S5I7G3JQL)
    Language English
    Publishing date 2023-05-11
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 80074-0
    ISSN 1471-6771 ; 0007-0912
    ISSN (online) 1471-6771
    ISSN 0007-0912
    DOI 10.1016/j.bja.2023.04.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Interdisciplinary Simulation Courses to Train Residents on Communication of Unexpected Complications from Perioperative Care: A Randomized Comparison of Within-Event (Microdebriefing) and Postscenario Debriefing.

    Szmulewicz, Claire / Rouby, Pascal / Boyer, Caroline / Benhamou, Dan / Capmas, Perrine

    Journal of surgical education

    2024  

    Abstract: Introduction: Training to disclose bad news in a pluridisciplinary format facilitates communication and improves learning. There are many different debriefing methods described in the literature. The aim of this study was to compare and evaluate the ... ...

    Abstract Introduction: Training to disclose bad news in a pluridisciplinary format facilitates communication and improves learning. There are many different debriefing methods described in the literature. The aim of this study was to compare and evaluate the value of final debriefing and microdebriefing with interruptions of the scenario in a simulation program about communication in unexpected complications from perioperative care.
    Methods: We conducted a prospective, randomized, single center study between October 2018 and July 2019 in a simulation center. Three scenarios were related to patient or family disclosure of complications which had occurred during gynecologic surgery by a dyad involving 2 residents (a gynecology and an anesthesia resident). All sessions involved 6 residents (3 gynecologist and 3 anesthesiologist). The main outcome measure was the immediate residents' self-assessment of the impact of the course on their medical practice immediately after the session.
    Results: We performed 15 simulation sessions including 80 residents. Thirty-nine residents were included in final debriefing group and 41 in micro-debriefing group. There was no significant difference on the impact for medical practice between groups (9.3/10 in the micro-debriefing group versus 9.2 in the final debriefing group (p = 0.53)). The overall satisfaction was high in the 2 group (9.1/10 in the 2 groups).
    Conclusion: This study is the first one to compare two debriefing methods in case of breaking bad news simulation. No difference between the 2 techniques was found concerning the students' feelings and short and long-term improvement of their communication skills.
    Language English
    Publishing date 2024-04-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2277538-9
    ISSN 1878-7452 ; 1931-7204
    ISSN (online) 1878-7452
    ISSN 1931-7204
    DOI 10.1016/j.jsurg.2024.03.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Subcostal TAP block: one or two sequential injections? A cadaveric study.

    Schaefer, Augustin / Grousson, Sébastien / Bessede, Thomas / Benhamou, Dan / Ruscio, Laura

    Regional anesthesia and pain medicine

    2024  

    Abstract: Background and objectives: The subcostal transversus abdominis plane block (scTAPB) provides analgesia to the anterior abdominal wall but analgesic spread following a single injection remains modest and variable. The oblique scTAPB, which is performed ... ...

    Abstract Background and objectives: The subcostal transversus abdominis plane block (scTAPB) provides analgesia to the anterior abdominal wall but analgesic spread following a single injection remains modest and variable. The oblique scTAPB, which is performed with a continuous injection during needle progression into the TAP along the oblique subcostal line, may extend the block to the whole anterior abdominal wall but needle progression by hydrodissection may be difficult, explaining why this block is not widely used. This study investigated if two sequential scTAPB injections (2scTAPI) may reach more nerves than a single scTAPB (1scTAPI).
    Methods: After institutional approval and under ultrasound guidance, a single injection of 20 mL of blue dye was performed in 16 cadaveric subjects into the TAP along the costal margin and lateral to the semilunaris line (1scTAPI). On the opposite side, a 20 mL of green solution was split into two injections (2scTAPI), using one injection medial and one lateral to the semilunaris line. Dye spread was assessed via gross anatomical dissection using an indirect method to quantify the involvement of the anterior cutaneous branches of the intercostal nerves with each technique. A nerve was considered stained if the dye was observed in the TAP, reaching the costal margin aligned with the bony extremity of its corresponding rib.
    Results: According to the spread to the costal margin, the estimated median number of consecutive nerves reached by dye after 2scTAPI was 5 (IQR 5-6) vs 3 (IQR 3-4) for 1scTAPI (p=0.00001). Spread after 2scTAPI suggested coverage of nerves originating from T8 to T12 in 85% of the subjects, and from T7 to T12 in 5 out of 17 cases. Spread following the 1scTAPI suggested coverage of nerves from T9 to T11 in most cases.
    Conclusions: In a cadaveric model, a larger spread at the costal margin was obtained after 2scTAPI, suggesting a greater coverage of anterior branches of abdominal wall nerves compared with 1scTAPI. Clinical studies are needed to confirm these results.
    Language English
    Publishing date 2024-02-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 1425299-5
    ISSN 1532-8651 ; 1098-7339 ; 0146-521X
    ISSN (online) 1532-8651
    ISSN 1098-7339 ; 0146-521X
    DOI 10.1136/rapm-2023-105079
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Ketorolac dose-response for acute pain is well known and the safety rules for adequate prescribing are clear.

    Benhamou, Dan

    Journal of clinical anesthesia

    2017  Volume 44, Page(s) 86

    MeSH term(s) Acute Pain ; Anti-Inflammatory Agents, Non-Steroidal ; Double-Blind Method ; Humans ; Ketorolac ; Pain, Postoperative
    Chemical Substances Anti-Inflammatory Agents, Non-Steroidal ; Ketorolac (YZI5105V0L)
    Language English
    Publishing date 2017-11-21
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1011618-7
    ISSN 1873-4529 ; 0952-8180
    ISSN (online) 1873-4529
    ISSN 0952-8180
    DOI 10.1016/j.jclinane.2017.10.016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Radial artery puncture and ultrasound imaging: Three reasons why.

    Zetlaoui, Paul J / Benhamou, Dan

    Anaesthesia, critical care & pain medicine

    2021  Volume 40, Issue 2, Page(s) 100844

    MeSH term(s) Catheterization, Peripheral ; Humans ; Punctures ; Radial Artery/diagnostic imaging ; Ultrasonography ; Vascular Surgical Procedures
    Language English
    Publishing date 2021-03-24
    Publishing country France
    Document type Editorial ; Comment
    ISSN 2352-5568
    ISSN (online) 2352-5568
    DOI 10.1016/j.accpm.2021.100844
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Fasting or eating during labour? It is time to move forward.

    Bouvet, Lionel / Bonnet, Marie-Pierre / Keita-Meyer, Hawa / Benhamou, Dan

    Anaesthesia, critical care & pain medicine

    2023  Volume 43, Issue 1, Page(s) 101311

    MeSH term(s) Pregnancy ; Female ; Humans ; Labor, Obstetric ; Fasting ; Preoperative Care
    Language English
    Publishing date 2023-10-20
    Publishing country France
    Document type Editorial
    ISSN 2352-5568
    ISSN (online) 2352-5568
    DOI 10.1016/j.accpm.2023.101311
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Good Luck ACCPM.

    Lefrant, Jean Yves / Pirracchio, Romain / Benhamou, Dan / Lorne, Emmanuel / Roquilly, Antoine

    Anaesthesia, critical care & pain medicine

    2023  Volume 43, Issue 1, Page(s) 101329

    Language English
    Publishing date 2023-11-20
    Publishing country France
    Document type Editorial
    ISSN 2352-5568
    ISSN (online) 2352-5568
    DOI 10.1016/j.accpm.2023.101329
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Epidural blood patch: A narrative review.

    Zetlaoui, Paul J / Buchheit, Thomas / Benhamou, Dan

    Anaesthesia, critical care & pain medicine

    2022  Volume 41, Issue 5, Page(s) 101138

    Abstract: The epidural blood patch (EBP) is one of the most effective treatments for intracranial hypotension. Anesthesiologists are familiar with performing EBPs for the treatment of dural puncture-associated intracranial hypotension following spinal anesthesia, ... ...

    Abstract The epidural blood patch (EBP) is one of the most effective treatments for intracranial hypotension. Anesthesiologists are familiar with performing EBPs for the treatment of dural puncture-associated intracranial hypotension following spinal anesthesia, complicated epidural analgesia, and diagnostic lumbar puncture. Increasingly, EBPs are used to treat patients with spontaneous intracranial hypotension. However, the treatment of these non-iatrogenic conditions presents new therapeutic challenges. The purpose of this narrative review is to discuss both procedural and diagnostic considerations of EBP for the various presentations of intracranial hypotension and allow the clinician to tailor treatment for the patient, especially in the setting of diagnostic dilemmas. After discussing EBP history and relevant anatomy, we review mechanisms of action and clinical indications for this intervention. The contraindications, complications, and treatment alternatives to the blood patch are examined in detail. Finally, objective methods to evaluate the effectiveness of the EBP, such as MRI or Doppler ultrasound, are presented as novel methods that may improve future diagnostic accuracy and treatment success.
    MeSH term(s) Analgesia, Epidural/adverse effects ; Anesthesia, Spinal/adverse effects ; Blood Patch, Epidural/adverse effects ; Blood Patch, Epidural/methods ; Humans ; Intracranial Hypotension/diagnosis ; Intracranial Hypotension/etiology ; Intracranial Hypotension/therapy ; Spinal Puncture
    Language English
    Publishing date 2022-08-02
    Publishing country France
    Document type Journal Article ; Review
    ISSN 2352-5568
    ISSN (online) 2352-5568
    DOI 10.1016/j.accpm.2022.101138
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Anaesthesia Critical Care & Pain Medicine: 9 years of international publication.

    Lefrant, Jean-Yves / Lorne, Emmanuel / Pirracchio, Romain / Benhamou, Dan / Milman, Alexandre / Roquilly, Antoine

    Anaesthesia, critical care & pain medicine

    2023  Volume 43, Issue 1, Page(s) 101328

    MeSH term(s) Humans ; Anesthesia ; Pain ; Anesthesiology ; Critical Care
    Language English
    Publishing date 2023-11-20
    Publishing country France
    Document type Editorial
    ISSN 2352-5568
    ISSN (online) 2352-5568
    DOI 10.1016/j.accpm.2023.101328
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Comparison of multimodal active learning and single-modality procedural simulation for central venous catheter insertion for incoming residents in anesthesiology: a prospective and randomized study.

    Blanie, Antonia / Shoaleh, Cécile / Marquion, Fabien / Benhamou, Dan

    BMC medical education

    2022  Volume 22, Issue 1, Page(s) 357

    Abstract: Background: Active learning methods, including low-fidelity simulation, are useful but the incremental learning effect of each method is however limited. We designed this study to assess if combining flipped classroom and the modified Peyton's « 4-steps» ...

    Abstract Background: Active learning methods, including low-fidelity simulation, are useful but the incremental learning effect of each method is however limited. We designed this study to assess if combining flipped classroom and the modified Peyton's « 4-steps» method during procedural simulation (intervention group [IG]) would provide better learning results than simulation alone (control group [CG]) in the context of central venous catheter insertion training.
    Methods: This prospective, single-center, and randomized study took place in 2017 in a single simulation center. All first year Anesthesiology residents of Ile de France area at the start of their residency were randomly included either in the IG or CG during a seminar aimed at providing initial procedural skills with low-fidelity simulation. A composite learning score which included knowledge MCQ and a questionnaire assessing satisfaction and value of the training session was recorded after training (primary outcome, /100). A randomized sub-group of learners of each group were video-recorded during central venous catheter insertion at the end of training and their skills were evaluated with validated tools, including a specific checklist and a global rating scale (GRS).
    Results: Among 89 anesthesiology residents, 48 and 41 learners were randomized in the intervention and control groups respectively. Of the IG residents, 40/48 (83%) had read the learning material prior to the session. There was no significant difference regarding the composite outcome ([IG]= 81.1 vs [CG] = 80.5 /100 (p = 0.68)). Results of the post-session MCQ knowledge questionnaire were also non-significantly different. Residents were similarly satisfied and described a significant improvement of their knowledge and skills after training. Learners highly valued the training session as a mean to improve their future practice. No significant differences regarding checklist and GRS scores were observed.
    Conclusions: A multimodal active learning strategy of procedural learning did not provide better learning outcomes when compared to a traditional simulation method. In both groups, satisfaction was high and perception of the acquired theoretical and practical knowledge was improved after training.
    MeSH term(s) Anesthesiology/education ; Catheterization, Central Venous ; Central Venous Catheters ; Clinical Competence ; Humans ; Internship and Residency ; Problem-Based Learning ; Prospective Studies
    Language English
    Publishing date 2022-05-11
    Publishing country England
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 2044473-4
    ISSN 1472-6920 ; 1472-6920
    ISSN (online) 1472-6920
    ISSN 1472-6920
    DOI 10.1186/s12909-022-03437-0
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