LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 162

Search options

  1. Article ; Online: Bioactives and human health.

    Fraga, Cesar G / Oteiza, Patricia I

    Molecular aspects of medicine

    2023  Volume 89, Page(s) 101168

    Language English
    Publishing date 2023-01-05
    Publishing country England
    Document type Editorial
    ZDB-ID 197640-0
    ISSN 1872-9452 ; 0098-2997
    ISSN (online) 1872-9452
    ISSN 0098-2997
    DOI 10.1016/j.mam.2023.101168
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1189: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Book: Plant phenolics and human health

    Fraga, Cesar G.

    biochemistry, nutrition, and pharmacology

    (The Wiley-IUBMB series on biochemistry and molecular biology)

    2010  

    Author's details ed. by Cesar G. Fraga
    Series title The Wiley-IUBMB series on biochemistry and molecular biology
    Keywords Phenols / pharmacology ; Phenols / therapeutic use ; Flavonoids / pharmacology ; Flavonoids / therapeutic use ; Nutritive Value ; Plant Extracts / pharmacology ; Plant Extracts / therapeutic use ; Review Literature as topic ; Phenols/Physiological effect ; Flavonoids/Physiological effect ; Phytochemicals/Physiological effect ; Nutrition
    Subject code 547.632
    Language English
    Size XII, 593 S. : Ill., graph. Darst.
    Publisher Wiley
    Publishing place Hoboken, NJ
    Publishing country United States
    Document type Book
    HBZ-ID HT016030557
    ISBN 0-470-28721-7 ; 978-0-470-28721-7
    Database Catalogue ZB MED Medicine, Health

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2010 A 482 order for loan Magazin

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Book: Plant phenolics and human health

    Fraga, Cesar G.

    biochemistry, nutrition, and pharmacology

    (The Wiley-IUBMB series on biochemistry and molecular biology)

    2010  

    Author's details ed. by Cesar G. Fraga
    Series title The Wiley-IUBMB series on biochemistry and molecular biology
    Keywords Phenols / pharmacology ; Phenols / therapeutic use ; Flavonoids / pharmacology ; Flavonoids / therapeutic use ; Nutritive Value ; Plant Extracts / pharmacology ; Plant Extracts / therapeutic use ; Review Literature as topic ; Phenols/Physiological effect ; Flavonoids/Physiological effect ; Phytochemicals/Physiological effect ; Nutrition
    Subject code 547.632
    Language English
    Size XII, 593 S. : Ill., graph. Darst.
    Publisher Wiley
    Publishing place Hoboken, NJ
    Publishing country United States
    Document type Book
    HBZ-ID HT016030557
    ISBN 0-470-28721-7 ; 978-0-470-28721-7
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

    More links

    Kategorien

    In stock of ZB MED Bonn / Germany

    Shelf markLoan statusLocation
    098/1168 available for loan (reading room) Freihandmagazin (U1)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  4. Article: Natural Products and Diabetes: (-)-Epicatechin and Mechanisms Involved in the Regulation of Insulin Sensitivity.

    Fraga, Cesar G / Cremonini, Eleonora / Galleano, Monica / Oteiza, Patricia I

    Handbook of experimental pharmacology

    2024  

    Abstract: Type 2 diabetes (T2D) is a disease that occurs when cells do not respond normally to insulin, a condition called insulin resistance, which leads to high blood glucose levels. Although it can be treated pharmacologically, dietary habits beyond ... ...

    Abstract Type 2 diabetes (T2D) is a disease that occurs when cells do not respond normally to insulin, a condition called insulin resistance, which leads to high blood glucose levels. Although it can be treated pharmacologically, dietary habits beyond carbohydrate restriction can be highly relevant in the management of T2D. Emerging evidence supports the possibility that natural products (NPs) could contribute to managing blood glucose or counteract the undesirable effects of hyperglycemia and insulin resistance. This chapter summarizes the relevant preclinical evidence involving the flavonoid (-)-epicatechin (EC) in the optimization of glucose homeostasis, reducing insulin resistance and/or diabetes-associated disorders. Major effects of EC are observed on (i) intestinal functions, including digestive enzymes, glucose transporters, microbiota, and intestinal permeability, and (ii) redox homeostasis, including oxidative stress and inflammation. There is still a need for further clinical studies to confirm the in vitro and rodent data, allowing recommendations for EC, particularly in prediabetic and T2D patients. The collection of similar data and the lack of clinical evidence for EC is also applicable to other NPs.
    Language English
    Publishing date 2024-03-01
    Publishing country Germany
    Document type Journal Article
    ISSN 0171-2004
    ISSN 0171-2004
    DOI 10.1007/164_2024_707
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Sign. bis Bd. 125 (1997): 1982 A 2146: Show issues
     danach: Sign. bei den Einzelbänden: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Corrigendum to "(-)-Epicatechin prevents TNFα-induced activation of signaling cascades involved in inflammation and insulin sensitivity in 3T3-L1 adipocytes" [Arch Biochem Biophys. (2012 Nov 15) 527 (2) 113-8, doi: 10.1016/j.abb.2012.02.019. Epub 2012 Mar 8].

    Vazquez-Prieto, Marcela A / Bettaieb, Ahmed / Haj, Fawaz G / Fraga, César G / Oteiza, Patricia I

    Archives of biochemistry and biophysics

    2024  , Page(s) 109992

    Language English
    Publishing date 2024-04-24
    Publishing country United States
    Document type Published Erratum
    ZDB-ID 523-x
    ISSN 1096-0384 ; 0003-9861
    ISSN (online) 1096-0384
    ISSN 0003-9861
    DOI 10.1016/j.abb.2024.109992
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Uc I Zs.237: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article ; Online: (Poly)phenols and the regulation of NADPH oxidases.

    Fraga, Cesar G / Oteiza, Patricia I / Hid, Ezequiel J / Galleano, Monica

    Redox biology

    2023  Volume 67, Page(s) 102927

    Abstract: Nicotinamide adenine dinucleotide phosphate (NADPH) oxidases (NOXs) are enzymes that generate superoxide anion ( ... ...

    Abstract Nicotinamide adenine dinucleotide phosphate (NADPH) oxidases (NOXs) are enzymes that generate superoxide anion (O
    MeSH term(s) Animals ; Humans ; Reactive Oxygen Species/metabolism ; Phenols ; Hydrogen Peroxide/metabolism ; Phenol ; NADPH Oxidases/metabolism ; NADPH Oxidase 1 ; Mammals/metabolism
    Chemical Substances Reactive Oxygen Species ; Phenols ; Hydrogen Peroxide (BBX060AN9V) ; Phenol (339NCG44TV) ; NADPH Oxidases (EC 1.6.3.-) ; NADPH Oxidase 1 (EC 1.6.3.-)
    Language English
    Publishing date 2023-10-17
    Publishing country Netherlands
    Document type Journal Article ; Review ; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, Non-U.S. Gov't
    ZDB-ID 2701011-9
    ISSN 2213-2317 ; 2213-2317
    ISSN (online) 2213-2317
    ISSN 2213-2317
    DOI 10.1016/j.redox.2023.102927
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article ; Online: Polyphenols and health.

    Croft, Kevin D / Fraga, Cesar G

    Food & function

    2020  Volume 11, Issue 10, Page(s) 8405–8406

    MeSH term(s) Animals ; Antioxidants ; Diet ; Flavonoids ; Health Status ; Humans ; Nutritional Status ; Polyphenols
    Chemical Substances Antioxidants ; Flavonoids ; Polyphenols
    Language English
    Publishing date 2020-11-05
    Publishing country England
    Document type Editorial
    ZDB-ID 2612033-1
    ISSN 2042-650X ; 2042-6496
    ISSN (online) 2042-650X
    ISSN 2042-6496
    DOI 10.1039/d0fo90042g
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Bonn / Germany

    Z 7872: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  8. Article ; Online: Anthocyanin actions at the gastrointestinal tract: Relevance to their health benefits.

    Oteiza, Patricia I / Cremonini, Eleonora / Fraga, Cesar G

    Molecular aspects of medicine

    2022  Volume 89, Page(s) 101156

    Abstract: Anthocyanins (AC) are flavonoids abundant in the human diet, which consumption has been associated to several health benefits, including the mitigation of cardiovascular disease, type 2 diabetes, non-alcoholic fatty liver disease, and neurological ... ...

    Abstract Anthocyanins (AC) are flavonoids abundant in the human diet, which consumption has been associated to several health benefits, including the mitigation of cardiovascular disease, type 2 diabetes, non-alcoholic fatty liver disease, and neurological disorders. It is widely recognized that the gastrointestinal (GI) tract is not only central for food digestion but actively participates in the regulation of whole body physiology. Given that AC, and their metabolites reach high concentrations in the intestinal lumen after food consumption, their biological actions at the GI tract can in part explain their proposed local and systemic health benefits. In terms of mechanisms of action, AC have been found to: i) inhibit GI luminal enzymes that participate in the absorption of lipids and carbohydrates; ii) preserve intestinal barrier integrity and prevent endotoxemia, inflammation and oxidative stress; iii) sustain goblet cell number, immunological functions, and mucus production; iv) promote a healthy microbiota; v) be metabolized by the microbiota to AC metabolites which will be absorbed and have systemic effects; and vi) modulate the metabolism of GI-generated hormones. This review will summarize and discuss the latest information on AC actions at the GI tract and their relationship to overall health benefits.
    MeSH term(s) Humans ; Anthocyanins ; Diabetes Mellitus, Type 2/metabolism ; Gastrointestinal Tract/metabolism ; Flavonoids/metabolism ; Diet
    Chemical Substances Anthocyanins ; Flavonoids
    Language English
    Publishing date 2022-11-12
    Publishing country England
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 197640-0
    ISSN 1872-9452 ; 0098-2997
    ISSN (online) 1872-9452
    ISSN 0098-2997
    DOI 10.1016/j.mam.2022.101156
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1189: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article ; Online: Curcumin Mitigates TNFα-Induced Caco-2 Cell Monolayer Permeabilization Through Modulation of NF-κB, ERK1/2, and JNK Pathways.

    Iglesias, Dario E / Cremonini, Eleonora / Oteiza, Patricia I / Fraga, Cesar G

    Molecular nutrition & food research

    2022  Volume 66, Issue 21, Page(s) e2101033

    Abstract: Scope: This work studies the capacity of curcumin to inhibit tumor necrosis alpha (TNFα)-induced inflammation, oxidative stress, and loss of intestinal barrier integrity, characterizing the underlying mechanisms.: Methods and results: Caco-2 cell ... ...

    Abstract Scope: This work studies the capacity of curcumin to inhibit tumor necrosis alpha (TNFα)-induced inflammation, oxidative stress, and loss of intestinal barrier integrity, characterizing the underlying mechanisms.
    Methods and results: Caco-2 cell monolayers are incubated with TNFα (10 ng mL
    Conclusion: The inhibition of NF-κB, ERK1/2, and JNK activation could be in part involved in the capacity of curcumin to mitigate intestinal inflammation, oxidant production, activation of redox-sensitive pathways, and prevention of monolayer permeabilization. These results support an action of dietary curcumin in sustaining gastrointestinal tract physiology.
    MeSH term(s) Humans ; Caco-2 Cells ; NF-kappa B/metabolism ; MAP Kinase Signaling System ; Mitogen-Activated Protein Kinase 3/metabolism ; Curcumin/pharmacology ; Tumor Necrosis Factor-alpha/pharmacology ; Tumor Necrosis Factor-alpha/metabolism ; Myosin Light Chains/metabolism ; Oxidants ; Inflammation
    Chemical Substances NF-kappa B ; Mitogen-Activated Protein Kinase 3 (EC 2.7.11.24) ; Curcumin (IT942ZTH98) ; Tumor Necrosis Factor-alpha ; Myosin Light Chains ; Oxidants
    Language English
    Publishing date 2022-03-03
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2160372-8
    ISSN 1613-4133 ; 1613-4125
    ISSN (online) 1613-4133
    ISSN 1613-4125
    DOI 10.1002/mnfr.202101033
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article ; Online: Bioactives and their impact on human health.

    Fraga, Cesar G / Oteiza, Patricia I

    Molecular aspects of medicine

    2018  Volume 61, Page(s) 1

    MeSH term(s) Health ; Humans ; Phytochemicals/pharmacology
    Chemical Substances Phytochemicals
    Language English
    Publishing date 2018-06-13
    Publishing country England
    Document type Editorial ; Introductory Journal Article
    ZDB-ID 197640-0
    ISSN 1872-9452 ; 0098-2997
    ISSN (online) 1872-9452
    ISSN 0098-2997
    DOI 10.1016/j.mam.2018.06.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1189: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top