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  1. Article: The Contribution of Anterior Segment Abnormalities to Changes in Intraocular Pressure in the DBA/2J Mouse Model of Glaucoma: DBA/2J-

    Rohowetz, Landon J / Mardelli, Marc E / Duncan, R Scott / Riordan, Sean M / Koulen, Peter

    Frontiers in neuroscience

    2022  Volume 15, Page(s) 801184

    Abstract: The contributions of anterior segment abnormalities to the development of ocular hypertension was determined in the DBA/2J mouse model of glaucoma. Intraocular pressure (IOP) was measured non-invasively. Iris pigment dispersion (IPD) and corneal ... ...

    Abstract The contributions of anterior segment abnormalities to the development of ocular hypertension was determined in the DBA/2J mouse model of glaucoma. Intraocular pressure (IOP) was measured non-invasively. Iris pigment dispersion (IPD) and corneal calcification were measured weekly starting at 20 weeks of age in DBA/2J and DBA/2J-
    Language English
    Publishing date 2022-02-03
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2411902-7
    ISSN 1662-453X ; 1662-4548
    ISSN (online) 1662-453X
    ISSN 1662-4548
    DOI 10.3389/fnins.2021.801184
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Physical activity and substance use among Canadian adolescents: Examining the moderating role of school connectedness.

    Fagan, Matthew James / Duncan, Markus J / Bedi, Robinder P / Puterman, Eli / Leatherdale, Scott T / Faulkner, Guy

    Frontiers in public health

    2022  Volume 10, Page(s) 889987

    Abstract: ... of this study was to examine the association between different types of physical activity [i.e., non-competitive ... physical activity (MVPA) per day] and substance use (i.e., current smoking, e-cigarette, cannabis, binge drinking ...

    Abstract Physical activity may play a role in promoting or preventing substance use among youth. The purpose of this study was to examine the association between different types of physical activity [i.e., non-competitive school sport, competitive school sport, outside of school sport and minutes of moderate to vigorous physical activity (MVPA) per day] and substance use (i.e., current smoking, e-cigarette, cannabis, binge drinking) among Canadian youth. Interaction effects between physical activity and school connectedness were also examined. Using data from the COMPASS study (2018-19;
    MeSH term(s) Adolescent ; Female ; Humans ; Male ; Electronic Nicotine Delivery Systems ; Binge Drinking/epidemiology ; Canada/epidemiology ; Schools ; Exercise ; Substance-Related Disorders/epidemiology
    Language English
    Publishing date 2022-11-10
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2711781-9
    ISSN 2296-2565 ; 2296-2565
    ISSN (online) 2296-2565
    ISSN 2296-2565
    DOI 10.3389/fpubh.2022.889987
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The Impact of Adjustment on Workplace Attitudes and Behaviors among Healthcare Workers during the COVID-19 Pandemic.

    Griffin, Brandon J / Coyle, Patrick T / Weber, Marcela C / Benight, Charles C / Morison, Margaret / Maguen, Shira / Pyne, Jeffrey / Duncan, Matthew S / Brady, Robert E / Wright, Hannah / Love, Tiffany / Langenecker, Scott A / Smith, Andrew J

    Journal of occupational and environmental medicine

    2024  

    Abstract: Objective: We examined the impact of healthcare workers' (HCWs) adjustment to the COVID-19 pandemic on their work-related attitudes and behaviors. Methods: HCWs (N = 1,468) participated in an observational longitudinal study in which they completed ... ...

    Abstract Objective: We examined the impact of healthcare workers' (HCWs) adjustment to the COVID-19 pandemic on their work-related attitudes and behaviors. Methods: HCWs (N = 1,468) participated in an observational longitudinal study in which they completed surveys of anxiety and occupational health between 2020 and 2021. Results: Most HCWs reported anxiety that was consistently below the diagnostic threshold (68%) or fell below the threshold within a year (16%). Others reported consistently high (14%) or increasing (2%) anxiety, especially women, younger HCWs, those with a weakened immune system, and allied health professionals. Consistently high or increasing anxiety was associated with poorer job satisfaction, work engagement, perceived supervisor support, burnout, and turnover intentions. Conclusions: Resources to support HCWs may be focused on those who report consistently high or increasing anxiety to minimize the effects of crises and disasters on the workforce.
    Language English
    Publishing date 2024-02-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1223932-x
    ISSN 1536-5948 ; 1076-2752
    ISSN (online) 1536-5948
    ISSN 1076-2752
    DOI 10.1097/JOM.0000000000003066
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Sociodemographic differences in 24-hour time-use behaviours in New Zealand children.

    Hedayatrad, Leila / Stewart, Tom / Paine, Sarah-Jane / Marks, Emma / Walker, Caroline / Duncan, Scott

    The international journal of behavioral nutrition and physical activity

    2022  Volume 19, Issue 1, Page(s) 131

    Abstract: ... each day (i.e., 24-h time-use behaviours), is related to physical and mental health outcomes. Currently ... residence location (i.e., urban vs. rural) were associated with meeting the physical activity guideline ...

    Abstract Background: The time that children spend in physical activity, sedentary behaviour, and sleep each day (i.e., 24-h time-use behaviours), is related to physical and mental health outcomes. Currently, there is no comprehensive evidence on New Zealand school-aged children's 24-h time-use behaviours, adherence to the New Zealand 24-h Movement Guidelines, and how these vary among different sociodemographic groups.
    Methods: This study utilises data from the 8-year wave of the Growing Up in New Zealand longitudinal study. Using two Axivity AX3 accelerometers, children's 24-h time-use behaviours were described from two perspectives: activity intensity and activity type. Compositional data analysis techniques were used to explore the differences in 24-h time-use compositions across various sociodemographic groups.
    Results: Children spent on average, 31.1%, 22.3%, 6.8%, and 39.8% of their time in sedentary, light physical activity, moderate-to-vigorous physical activity, and sleep, respectively. However, the daily distribution of time in different activity types was 33.2% sitting, 10.8% standing, 7.3% walking, 0.4% running, and 48.2% lying. Both the activity intensity and activity type compositions varied across groups of child ethnicity, gender, and household income or deprivation. The proportion of children meeting each of the guidelines was 90% for physical activity, 62.5% for sleep, 16% for screen time, and 10.6% for the combined guidelines. Both gender and residence location (i.e., urban vs. rural) were associated with meeting the physical activity guideline, whereas child ethnicity, mother's education and residence location were associated with meeting the screen time guideline. Child ethnicity and mother's education were also significantly associated with the adherence to the combined 24-h Movement Guidelines.
    Conclusions: This study provided comprehensive evidence on how New Zealand children engage in 24-h time-use behaviours, adherence to the New Zealand 24-h Movement Guidelines, and how these behaviours differ across key sociodemographic groups. These findings should be considered in designing future interventions for promoting healthy time-use patterns in New Zealand children.
    MeSH term(s) Child ; Exercise ; Humans ; Longitudinal Studies ; New Zealand ; Screen Time ; Sedentary Behavior ; Sleep
    Language English
    Publishing date 2022-10-04
    Publishing country England
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 2134691-4
    ISSN 1479-5868 ; 1479-5868
    ISSN (online) 1479-5868
    ISSN 1479-5868
    DOI 10.1186/s12966-022-01358-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Increasing Prevalence of Cerebral Palsy Among Two-Year-Old Children Born at <27 Weeks of Gestation: A Cohort Study.

    DeMauro, Sara B / McDonald, Scott A / Heyne, Roy J / Vohr, Betty R / Duncan, Andrea F / Newman, Jamie E / Das, Abhik / Hintz, Susan R

    The Journal of pediatrics

    2024  Volume 268, Page(s) 113944

    Abstract: Objective: To evaluate changes in prevalence and severity of cerebral palsy (CP) among surviving children born at <27 weeks of gestation over time and to determine associations between CP and other developmental domains, functional impairment, medical ... ...

    Abstract Objective: To evaluate changes in prevalence and severity of cerebral palsy (CP) among surviving children born at <27 weeks of gestation over time and to determine associations between CP and other developmental domains, functional impairment, medical morbidities, and resource use among 2-year-old children who were born extremely preterm.
    Study design: Retrospective cohort study using prospective registry data, conducted at 25 centers of the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Participants were children born at <27 weeks of gestation and followed at 18 through 26 months of corrected age from 2008 through 2019. Outcomes of interest were changes in prevalence of any CP and severity of CP over time and associations between CP and other neurodevelopmental outcomes, functional impairment, and medical comorbidities. Adjusted logistic, linear, multinomial logistic, and robust Poisson regression evaluated the relationships between child characteristics, CP severity, and outcomes.
    Results: Among 6927 surviving children with complete follow-up data, 3717 (53.7%) had normal neurologic examinations, 1303 (18.8%) had CP, and the remainder had abnormal neurologic examinations not classified as CP. Adjusted rates of any CP increased each year of the study period (aOR 1.11 per year, 95% CI 1.08-1.14). Cognitive development was significantly associated with severity of CP. Children with CP were more likely to have multiple medical comorbidities, neurosensory problems, and poor growth at follow-up.
    Conclusions: The rate of CP among surviving children who were born extremely preterm increased from 2008 through 2019. At 18 to 26 months of corrected age, neurodevelopmental and medical comorbidities are strongly associated with all severity levels of CP.
    MeSH term(s) Humans ; Cerebral Palsy/epidemiology ; Female ; Child, Preschool ; Prevalence ; Male ; Retrospective Studies ; Infant, Newborn ; Infant, Extremely Premature ; Gestational Age ; Severity of Illness Index ; United States/epidemiology ; Infant ; Cohort Studies ; Registries
    Language English
    Publishing date 2024-02-08
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Multicenter Study
    ZDB-ID 3102-1
    ISSN 1097-6833 ; 0022-3476
    ISSN (online) 1097-6833
    ISSN 0022-3476
    DOI 10.1016/j.jpeds.2024.113944
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Lateral line morphology, sensory perception and collective behaviour in African cichlid fish.

    Scott, Elliott / Edgley, Duncan E / Smith, Alan / Joyce, Domino A / Genner, Martin J / Ioannou, Christos C / Hauert, Sabine

    Royal Society open science

    2023  Volume 10, Issue 1, Page(s) 221478

    Abstract: The lateral line system of fishes provides cues for collective behaviour, such as shoaling, but it remains unclear how anatomical lateral line variation leads to behavioural differences among species. Here we studied associations between lateral line ... ...

    Abstract The lateral line system of fishes provides cues for collective behaviour, such as shoaling, but it remains unclear how anatomical lateral line variation leads to behavioural differences among species. Here we studied associations between lateral line morphology and collective behaviour using two morphologically divergent species and their second-generation hybrids. We identify collective behaviours associated with variation in canal and superficial lateral line morphology, with closer proximities to neighbouring fish associated with larger canal pore sizes and fewer superficial neuromasts. A mechanistic understanding of the observed associations was provided by hydrodynamic modelling of an artificial lateral line sensor, which showed that simulated canal-based neuromasts were less susceptible to saturation during unidirectional movement than simulated superficial neuromasts, while increasing the canal pore size of the simulated lateral line sensor elevated sensitivity to vortices shed by neighbouring fish. Our results propose a mechanism behind lateral line flow sensing during collective behaviour in fishes.
    Language English
    Publishing date 2023-01-25
    Publishing country England
    Document type Journal Article
    ZDB-ID 2787755-3
    ISSN 2054-5703
    ISSN 2054-5703
    DOI 10.1098/rsos.221478
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: PRESUMPTIVE CONGENITAL HYPOTHYROIDISM IN RED PANDAS (

    Eustace, Ronan / Agnew, Dalen / Fitzgerald, Scott D / Fyfe, John C / Duncan, Ann E / Petroff, Brian / Thompson, Kimberly A

    Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians

    2021  Volume 52, Issue 2, Page(s) 795–805

    Abstract: High neonatal mortality among red pandas ( ...

    Abstract High neonatal mortality among red pandas (
    Language English
    Publishing date 2021-06-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2174930-9
    ISSN 1937-2825 ; 1042-7260
    ISSN (online) 1937-2825
    ISSN 1042-7260
    DOI 10.1638/2020-0122
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Lateral line morphology, sensory perception and collective behaviour in African cichlid fish

    Elliott Scott / Duncan E. Edgley / Alan Smith / Domino A. Joyce / Martin J. Genner / Christos C. Ioannou / Sabine Hauert

    Royal Society Open Science, Vol 10, Iss

    2023  Volume 1

    Abstract: The lateral line system of fishes provides cues for collective behaviour, such as shoaling, but it remains unclear how anatomical lateral line variation leads to behavioural differences among species. Here we studied associations between lateral line ... ...

    Abstract The lateral line system of fishes provides cues for collective behaviour, such as shoaling, but it remains unclear how anatomical lateral line variation leads to behavioural differences among species. Here we studied associations between lateral line morphology and collective behaviour using two morphologically divergent species and their second-generation hybrids. We identify collective behaviours associated with variation in canal and superficial lateral line morphology, with closer proximities to neighbouring fish associated with larger canal pore sizes and fewer superficial neuromasts. A mechanistic understanding of the observed associations was provided by hydrodynamic modelling of an artificial lateral line sensor, which showed that simulated canal-based neuromasts were less susceptible to saturation during unidirectional movement than simulated superficial neuromasts, while increasing the canal pore size of the simulated lateral line sensor elevated sensitivity to vortices shed by neighbouring fish. Our results propose a mechanism behind lateral line flow sensing during collective behaviour in fishes.
    Keywords lateral line ; collective behaviour ; bioinspiration ; sensors ; cichlids ; Science ; Q
    Subject code 590
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher The Royal Society
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Bacterial Genotype, Carrier Risk Factors, and an Antimicrobial Stewardship Approach Relevant to Methicillin-resistant

    Breed, Matthew W / Perez, Hannah L / Otto, Michael / Villaruz, Amer E / Weese, J Scott / Alvord, Gregory W / Donohue, Duncan E / Washington, Franchasca / Kramer, Joshua A

    Comparative medicine

    2023  

    Abstract: Methicillin- ... ...

    Abstract Methicillin-resistant
    Language English
    Publishing date 2023-03-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2006425-1
    ISSN 2769-819X ; 0023-6764 ; 1532-0820
    ISSN (online) 2769-819X
    ISSN 0023-6764 ; 1532-0820
    DOI 10.30802/AALAS-CM-22-000018
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Support for mask use as a COVID-19 public health measure among a large sample of Canadian secondary school students.

    Patte, Karen A / Wade, Terrance J / MacNeil, Adam J / Bélanger, Richard E / Duncan, Markus J / Riazi, Negin / Leatherdale, Scott T

    BMC public health

    2022  Volume 22, Issue 1, Page(s) 1598

    Abstract: Background: Youth voice has been largely absent from deliberations regarding public health measures intended to prevent SARS-CoV-2 transmission, despite being one of the populations most impacted by school-based policies. To inform public health ... ...

    Abstract Background: Youth voice has been largely absent from deliberations regarding public health measures intended to prevent SARS-CoV-2 transmission, despite being one of the populations most impacted by school-based policies. To inform public health strategies and messages, we examined the level of student support of mask use in public spaces and school mask requirements, as well as factors associated with students' perspectives.
    Methods: We used cross-sectional survey data from 42,767 adolescents attending 133 Canadian secondary schools that participated in the COMPASS study during the 2020/2021 school year. Multinomial regression models assessed support for i) wearing a mask in indoor public spaces and ii) schools requiring students to wear masks, in association with COVID-19 knowledge, concerns, and perceived risk.
    Results: Wearing masks in indoor public spaces was supported by 81.9% of students; 8.7% were unsupportive and 9.4% were neutral/undecided. School mask requirements were supported by 67.8%, with 23.1% neutral and 9.1% unsupportive. More females supported mask wearing in public spaces (83.9% vs. 79.1%) and school mask requirements (70.8% vs. 63.5%) than males. Students had increased odds of supporting mask use in public spaces and school mask requirements if they reported concerns about their own or their family's health, had discussions regarding ways to prevent infection, perceived COVID-19 to be a risk to young people, and knew that signs are not always present in COVID-19 cases and that masks prevent SARS-CoV-2 transmission if someone coughs.
    Conclusions: During the year following the beginning of the pandemic, most students supported the required use of masks in schools and wearing masks in indoor public spaces. Improving knowledge around the effectiveness of masks appears likely to have the largest impact on mask support in adolescent populations among the factors studied.
    MeSH term(s) Adolescent ; COVID-19/epidemiology ; COVID-19/prevention & control ; Canada/epidemiology ; Cross-Sectional Studies ; Female ; Humans ; Male ; Public Health ; SARS-CoV-2 ; Schools ; Students
    Language English
    Publishing date 2022-08-22
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2041338-5
    ISSN 1471-2458 ; 1471-2458
    ISSN (online) 1471-2458
    ISSN 1471-2458
    DOI 10.1186/s12889-022-14011-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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