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Article ; Online: Is the combination of depression symptoms and multimorbidity associated with the increase of the prevalence of functional disabilities in Brazilian older adults? A cross-sectional study.

da Rosa, Patrícia Pereira de Souza / Marques, Larissa Pruner / Corrêa, Vanessa Pereira / De Oliveira, Cesar / Schneider, Ione Jayce Ceola

Frontiers in aging

2023 Volume 4, Page(s) 1188552

Abstract: Introduction: ...

Abstract	Introduction:
Language	English
Publishing date	2023-05-23
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	3076785-4
ISSN	2673-6217 ; 2673-6217
ISSN (online)	2673-6217
ISSN	2673-6217
DOI	10.3389/fragi.2023.1188552
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Article ; Online: The burden of coronary heart disease in simultaneous pancreas-kidney transplantation: coronary angiography as a diagnostic method for all? - a retrospective study.

Marques, Joana / Pereira, Luísa / Messias, Ana / Fonseca, Nuno / Cotovio, Patrícia / Ferreira, Aníbal / Nolasco, Fernando

Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia

2022 Volume 44, Issue 4, Page(s) 522–526

Abstract: Introduction: Type 1 diabetes mellitus is associated with an increased risk of coronary artery disease, which is frequently asymptomatic. This risk increases significantly in those with nephropathy. In selected patients, simultaneous pancreas-kidney ... ...

Abstract	Introduction: Type 1 diabetes mellitus is associated with an increased risk of coronary artery disease, which is frequently asymptomatic. This risk increases significantly in those with nephropathy. In selected patients, simultaneous pancreas-kidney transplantation is the renal and pancreatic replacement therapy of choice, as it increases longevity and stabilizes diabetic complications. Despite essential, universal screening protocols are still controversial for coronary artery disease in this population. Methods: We retrospectively analysed 99 simultaneous pancreas-kidney recipients from our centre from 2011 to 2018 and selected 77 patients who underwent coronary angiography during the pre-transplant evaluation. Our aim was to identify potential risk factors associated with significant lesions on coronary angiography. Results: Almost half of our cohort of 77 candidates submitted to coronary angiography had coronary artery disease. Of these, nearly 30% underwent revascularization, although only one of them reported symptoms of myocardial ischemia. In a univariate analysis, the presence of smoking habits was the only risk factor for coronary artery disease. We also found that 20 or more years of type 1 diabetes mellitus was significantly associated with the presence of coronaropathy. Discussion: Selection of diabetic candidates with acceptable cardiac risk before simultaneous pancreas-kidney transplantation is imperative. Given the impact of a correct diagnosis and a low procedural risk, we defend the routine use of coronary angiography as the initial screening method for coronary artery disease in this population. Particularly care must be taken in evaluating asymptomatic patients with long-term type 1 diabetes mellitus and smokers.
MeSH term(s)	Humans ; Coronary Angiography ; Coronary Artery Disease/diagnostic imaging ; Coronary Artery Disease/surgery ; Retrospective Studies ; Diabetes Mellitus, Type 1/complications ; Kidney Transplantation ; Risk Factors ; Pancreas
Language	Portuguese
Publishing date	2022-02-24
Publishing country	Brazil
Document type	Journal Article
ZDB-ID	2057873-8
ISSN	2175-8239 ; 2175-8239
ISSN (online)	2175-8239
ISSN	2175-8239
DOI	10.1590/2175-8239-JBN-2021-0156
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Article ; Online: Sexual rights and reproductive rights in the perception of

Vanessa dos Santos Pereira / Priscila Marques Nascimento / Ana Luiza de Oliveira Carvalho / Andreza Rodrigues / Patricia Lima Pereira Peres / Ana Beatriz Azevedo Queiroz

Revista de Pesquisa : Cuidado é Fundamental Online, Vol

women deprived of freedom / Direitos sexuais e direitos reprodutivos na percepção de: mulheres privadas de liberdade

2024 Volume 16

Abstract: Objetivo: analisar a percepção de mulheres privadas de liberdade quanto aos seus direitos sexuais e direitos reprodutivos. pesquisa descritiva, com abordagem qualitativa. Foram realizadas entrevistas com mulheres que estavam vivenciando a gestação (9) e ... ...

Abstract	Objetivo: analisar a percepção de mulheres privadas de liberdade quanto aos seus direitos sexuais e direitos reprodutivos. pesquisa descritiva, com abordagem qualitativa. Foram realizadas entrevistas com mulheres que estavam vivenciando a gestação (9) e o puerpério (4), em duas unidades prisionais do Rio de Janeiro. Método: pesquisa descritiva, com abordagem qualitativa. Foram realizadas entrevistas com mulheres que estavam vivenciando a gestação (9) e o puerpério (4), em duas unidades prisionais do Rio de Janeiro. O método de análise foi o Hermenêutico dialético. Resultados foram elencadas duas categorias: 1) Violações institucionais como infração dos direitos sexuais e dos direitos reprodutivos e 2) Contradições entre a possibilidade de exercer os direitos e as limitações impostas pelo sistema carcerário. Conclusão: as violações que essas mulheres sofrem, não estão restritas a elas. A luta pelos direitos das mulheres é um movimento constante. Os avanços são significativos, contudo, há amarras reais que impedem que as mulheres usufruam seus direitos sexuais e seus direitos reprodutivos, mesmo que eles existam no plano legal e normativo.
Keywords	Prisões ; Gravidez ; Pós parto ; Enfermagem ; Direitos Sexuais e Reprodutivos ; Medicine ; R ; Nursing ; RT1-120
Language	English
Publishing date	2024-01-01T00:00:00Z
Publisher	Universidade Federal do Estado do Rio de Janeiro
Document type	Article ; Online
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Article ; Online: Comparison between high-flow nasal oxygen (HFNO) alternated with non-invasive ventilation (NIV) and HFNO and NIV alone in patients with COVID-19: a retrospective cohort study.

da Cruz, Amanda Pereira / Martins, Gloria / Martins, Camila Marinelli / Marques, Victoria / Christovam, Samantha / Battaglini, Denise / Robba, Chiara / Pelosi, Paolo / Rocco, Patricia Rieken Macedo / Cruz, Fernanda Ferreira / Dos Santos Samary, Cynthia / Silva, Pedro Leme

European journal of medical research

2024 Volume 29, Issue 1, Page(s) 248

Abstract: Background: Non-invasive respiratory support (conventional oxygen therapy [COT], non-invasive ventilation [NIV], high-flow nasal oxygen [HFNO], and NIV alternated with HFNO [NIV + HFNO] may reduce the need for invasive mechanical ventilation (IMV) in ... ...

Abstract	Background: Non-invasive respiratory support (conventional oxygen therapy [COT], non-invasive ventilation [NIV], high-flow nasal oxygen [HFNO], and NIV alternated with HFNO [NIV + HFNO] may reduce the need for invasive mechanical ventilation (IMV) in patients with COVID-19. The outcome of patients treated non-invasively depends on clinical severity at admission. We assessed the need for IMV according to NIV, HFNO, and NIV + HFNO in patients with COVID-19 according to disease severity and evaluated in-hospital survival rates and hospital and intensive care unit (ICU) lengths of stay. Methods: This cohort study was conducted using data collected between March 2020 and July 2021. Patients ≥ 18 years admitted to the ICU with a diagnosis of COVID-19 were included. Patients hospitalized for < 3 days, receiving therapy (COT, NIV, HFNO, or NIV + HFNO) for < 48 h, pregnant, and with no primary outcome data were excluded. The COT group was used as reference for multivariate Cox regression model adjustment. Results: Of 1371 patients screened, 958 were eligible: 692 (72.2%) on COT, 92 (9.6%) on NIV, 31 (3.2%) on HFNO, and 143 (14.9%) on NIV + HFNO. The results for the patients in each group were as follows: median age (interquartile range): NIV (64 [49-79] years), HFNO (62 [55-70] years), NIV + HFNO (62 [48-72] years) (p = 0.615); heart failure: NIV (54.5%), HFNO (36.3%), NIV + HFNO (9%) (p = 0.003); diabetes mellitus: HFNO (17.6%), NIV + HFNO (44.7%) (p = 0.048). > 50% lung damage on chest computed tomography (CT): NIV (13.3%), HFNO (15%), NIV + HFNO (71.6%) (p = 0.038); SpO Conclusions: In patients with COVID-19, NIV alternating with HFNO was associated with a higher rate of IMV independent of the presence of comorbidities, chest CT score and SpO
Language	English
Publishing date	2024-04-22
Publishing country	England
Document type	Journal Article
ZDB-ID	1329381-3
ISSN	2047-783X ; 0949-2321
ISSN (online)	2047-783X
ISSN	0949-2321
DOI	10.1186/s40001-024-01826-3
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Article ; Online: Roland-Morris disability questionnaire is bidimensional and has 16 items when applied to community-dwelling older adults with low back pain.

Takara, Kelly Sayuri / Alamino Pereira de Viveiro, Larissa / Moura, Patricia Albuquerque / Marques Pasqual, Amélia / Pompeu, José Eduardo

Disability and rehabilitation

2022 Volume 45, Issue 15, Page(s) 2526–2532

Abstract: Purpose: To explore the evidence of the internal structure validity of the Roland-Morris Disability Questionnaire in older adults with low back pain.: Methods: This was a cross-sectional study of psychometric testing involving 528 older adults with ... ...

Abstract	Purpose: To explore the evidence of the internal structure validity of the Roland-Morris Disability Questionnaire in older adults with low back pain. Methods: This was a cross-sectional study of psychometric testing involving 528 older adults with low back pain. Internal structure validity was explored by exploratory factor analysis and semi-confirmatory factor analysis. Reliability was verified using Kuder-Richardson Formula 20, Cronbach's alpha, and McDonald's omega. Replicability was observed by the generalized H index. Results: Roland-Morris Disability Questionnaire displayed two factors that assess "functional capacity" and "mobility". Eight items were excluded for presenting cross-loading (2 and 10), inadequate loading factors and communalities (18, 24, 13, and 12), or did not relate to the latent construct (15 and 22). Semi-confirmatory factor analysis indicated that the questionnaire had a good fitness model [ Conclusions: The most appropriate version of the Roland-Morris Disability Questionnaire to apply to older adults with low back pain has 16 items and assesses functional capacity and mobility. IMPLICATIONS FOR REHABILITATIONThe RMDQ-16 is the most appropriate version of the RMDQ to use in older adults with LBP;The RMDQ-16 is bidimensional and assesses "functional capacity" and "mobility";The poor replicability of the RMDQ-16 indicates that it will probably not be stable across studies, but it can be useful in a clinical setting.
MeSH term(s)	Humans ; Aged ; Low Back Pain/diagnosis ; Reproducibility of Results ; Cross-Sectional Studies ; Independent Living ; Disability Evaluation ; Surveys and Questionnaires ; Psychometrics/methods ; Cross-Cultural Comparison
Language	English
Publishing date	2022-07-07
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1104775-6
ISSN	1464-5165 ; 0963-8288
ISSN (online)	1464-5165
ISSN	0963-8288
DOI	10.1080/09638288.2022.2096127
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Article: Spigelian hernia diagnosis: Case report.

da Silva, Danilo Vitorio Marques / Cordoval, João Lucas Azevedo / Vasconcelos, Lúcia Helena Ferreira / de Menezes, Flávia Martins / Bastos, Patricia Sanson Pereira / Chimeli-Ormonde, Luiza

International journal of surgery case reports

2023 Volume 106, Page(s) 108165

Abstract: Introduction and importance: Spigelian hernia is a rare abdominal wall hernia, representing 0.1 to 2 % of all ventral hernias. Clinically, the signs and symptoms are nonspecific and unclear.: Case presentation: Here, we present a 69-year-old female ... ...

Abstract	Introduction and importance: Spigelian hernia is a rare abdominal wall hernia, representing 0.1 to 2 % of all ventral hernias. Clinically, the signs and symptoms are nonspecific and unclear. Case presentation: Here, we present a 69-year-old female patient, with abdominal bulging in both iliac fossae. Imaging exams suggested Spigelian hernia and right inguinal hernia. The treatment was surgical, with placement of polypropylene meshes and the patient had an uneventful postoperative evolution. Clinical discussion: The characteristics of this case corroborate the current literature, which points to a greater involvement of adults aged between 40 and 70 years. The treatment of choice is surgery, which can be open or videolaparoscopic, with placement of a mesh or primary suture. Conclusion: The clinical presentation of Spigelian hernia is not characteristic and its diagnosis should be suspected during the investigation of an abdominal mass.
Language	English
Publishing date	2023-04-16
Publishing country	Netherlands
Document type	Case Reports
ISSN	2210-2612
ISSN	2210-2612
DOI	10.1016/j.ijscr.2023.108165
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Article ; Online: Nivolumab for newly and recurrent glioblastoma multiforme treatment: A systematic review and meta-analysis.

Araujo Moura, Alexandre Wendell / da Silva Rodrigues, Sirlene / de Oliveira, Taciana Freire / Lobato, Beatriz Marques / Pereira Cerize, Natalia Neto / Léo, Patricia

Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners

2023 Volume 29, Issue 7, Page(s) 1736–1747

Abstract: Objective: We conducted a systematic review and meta-analysis aiming to assess the efficacy and safety of Nivolumab treatment in patients with newly diagnosed and recurrent glioblastoma multiforme (GBM).: Data sources: Our study followed the ... ...

Abstract	Objective: We conducted a systematic review and meta-analysis aiming to assess the efficacy and safety of Nivolumab treatment in patients with newly diagnosed and recurrent glioblastoma multiforme (GBM). Data sources: Our study followed the guidelines outlined in the preferred reporting items for systematic reviews and meta-analyses (PRISMA) recommendations. The protocol for this review can be found in the International Prospective Register of Systematic Reviews Database (CRD42022340071). We performed searches on the Medline, PubMed, Embase, Scopus, and Web of Science databases. Data summary: A total of 545 studies were identified through our comprehensive search across the five databases (PubMed: 78, Embase: 82, Medline: 173, Scopus: 138, Web of Science: 74). After conducting a thorough analysis, our meta-analysis indicated that treatment with Nivolumab led to improved overall survival (OS) outcomes in newly diagnosed glioblastoma patients, as evidenced by a prolonged median OS based on trial data. However, there was no significant beneficial effect observed in terms of median progression-free survival (PFS), as well as OS at 6, 12, and 24 months. Furthermore, our results demonstrated no efficacy of Nivolumab in the treatment of recurrent GBM patients. Conclusions: In conclusion, Nivolumab demonstrated promising results that warrant further investigation for its use in newly diagnosed glioblastoma patients. However, its effectiveness was not observed in the context of recurrent GBM.
MeSH term(s)	Humans ; Glioblastoma/drug therapy ; Nivolumab/therapeutic use ; Neoplasm Recurrence, Local/drug therapy ; Progression-Free Survival ; Brain Neoplasms
Chemical Substances	Nivolumab (31YO63LBSN)
Language	English
Publishing date	2023-07-28
Publishing country	England
Document type	Meta-Analysis ; Systematic Review ; Journal Article ; Review
ZDB-ID	1330764-2
ISSN	1477-092X ; 1078-1552
ISSN (online)	1477-092X
ISSN	1078-1552
DOI	10.1177/10781552231190104
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Article ; Online: Evaluation of pediatric diabetes mellitus after SARS-CoV-2 infection: A long-term prospective case series.

Fink, Thais T / Canton, Ana P M / Pereira, Maria Fernanda B / Bain, Vera / Matsuo, Olívia / Astley, Camilla / Marques, Heloisa H S / Correa-Silva, Simone / Montenegro, Marilia M / Palmeira, Patricia / Garanito, Marlene P / Duarte, Alberto J S / Carneiro-Sampaio, Magda / Latronico, Ana C / Silva, Clovis A

Clinics (Sao Paulo, Brazil)

2023 Volume 78, Page(s) 100299

MeSH term(s)	Humans ; Child ; COVID-19 ; SARS-CoV-2 ; Diabetes Mellitus
Language	English
Publishing date	2023-11-20
Publishing country	United States
Document type	Letter
ZDB-ID	2182801-5
ISSN	1980-5322 ; 1807-5932
ISSN (online)	1980-5322
ISSN	1807-5932
DOI	10.1016/j.clinsp.2023.100299
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Article ; Online: Protective Effects of a synthetic glycosaminoglycan mimetic (OTR4132) in a rat immunotoxic lesion model of septohippocampal cholinergic degeneration.

Pereira, Patricia Marques / Papy-Garcia, Dulce / Barritault, Denis / Chiappini, Franck / Jackisch, Rolf / Schimchowitsch, Sarah / Cassel, Jean-Christophe

Glycoconjugate journal

2022 Volume 39, Issue 1, Page(s) 107–130

Abstract: Using a partial hippocampal cholinergic denervation model, we assessed the effects of the ... ...

Abstract	Using a partial hippocampal cholinergic denervation model, we assessed the effects of the RGTA
MeSH term(s)	Acetylcholinesterase ; Animals ; Cholinergic Agents/pharmacology ; Glycosaminoglycans/pharmacology ; Male ; Rats ; Rats, Long-Evans ; Ribosome Inactivating Proteins, Type 1
Chemical Substances	Cholinergic Agents ; Glycosaminoglycans ; Ribosome Inactivating Proteins, Type 1 ; Acetylcholinesterase (EC 3.1.1.7)
Language	English
Publishing date	2022-03-07
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	283770-5
ISSN	1573-4986 ; 0282-0080
ISSN (online)	1573-4986
ISSN	0282-0080
DOI	10.1007/s10719-022-10047-x
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Article ; Online: Nutrient Patterns and Risk of Osteopenia in Postmenopausal Women.

Grili, Patricia Paula da Fonseca / Vidigal, Camila Vilarinho / Cruz, Geise Ferreira da / Albergaria, Ben-Hur / Marques-Rocha, José Luiz / Pereira, Taísa Sabrina Silva / Guandalini, Valdete Regina

Nutrients

2023 Volume 15, Issue 7

Abstract: Nutrient patterns (NPs) and the synergistic effect between nutrients have been shown to be associated with changes in bone mineral density (BMD). This study aimed to identify NPs and to associate them with BMD categories in postmenopausal women. This ... ...

Abstract	Nutrient patterns (NPs) and the synergistic effect between nutrients have been shown to be associated with changes in bone mineral density (BMD). This study aimed to identify NPs and to associate them with BMD categories in postmenopausal women. This cross-sectional, observational, analytical study was carried out with women in menopause for at least 12 months, aged ≥50 years. Sociodemographic, lifestyle, and clinical variables were investigated. BMD was assessed using dual energy X-ray absorptiometry. A dietary assessment was conducted using a food frequency questionnaire, and three nutrient patterns (NP1, NP2, and NP3) were extracted from the principal component analysis. Multivariate logistic regression was applied to investigate the association between BMD classifications and NP consumption. A total of 124 women, aged on average, 66.8 ± 6.1 years, were evaluated. Of these, 41.9% had osteopenia and 36.3% had osteoporosis. The NP1 (OR: 6.64, [CI95%: 1.56-28.16];
MeSH term(s)	Female ; Humans ; Postmenopause ; Cross-Sectional Studies ; Bone Diseases, Metabolic/epidemiology ; Bone Diseases, Metabolic/etiology ; Bone Density ; Vitamins ; Vitamin A ; Osteoporosis, Postmenopausal/epidemiology ; Osteoporosis, Postmenopausal/etiology
Chemical Substances	Vitamins ; Vitamin A (11103-57-4)
Language	English
Publishing date	2023-03-29
Publishing country	Switzerland
Document type	Observational Study ; Journal Article
ZDB-ID	2518386-2
ISSN	2072-6643 ; 2072-6643
ISSN (online)	2072-6643
ISSN	2072-6643
DOI	10.3390/nu15071670
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