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Book: The chronic ear

Dornhoffer, John L. / Gluth, Michael B.

2016

Author's details	John L. Dornhoffer, Michael B. Gluth
Keywords	Ear Diseases / therapy ; Ear Diseases / diagnosis ; Chronic Disease
Language	English
Publisher	Thieme
Publishing place	New York u.a.
Publishing country	United States
Document type	Book
Note	Includes bibliographical references and index
HBZ-ID	HT018960745
ISBN	978-1-60406-864-1 ; 9781604068658 ; 1-60406-864-7 ; 1604068655
Database	Catalogue ZB MED Medicine, Health

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2016 A 1105	available for loan (reading room)	Lesesaal EG

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Article ; Online: On the Relationship Between Menière's Disease and Endolymphatic Hydrops.

Gluth, Michael B

Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology

2019 Volume 41, Issue 2, Page(s) 242–249

Abstract: ... those that can be modulated by mechanical manipulation of the basilar membrane and cochlear microphonic; B ...

Abstract	: The relationship between Menière's disease and endolymphatic hydrops is ambiguous. On the one hand, the existence of cases of endolymphatic hydrops lacking the classic symptoms of Menière's disease has prompted the assertion that endolymphatic hydrops alone is insufficient to cause symptoms and drives the hypothesis that endolymphatic hydrops is a mere epiphenomenon. Yet, on the other hand, there is considerable evidence suggesting a relationship between the mechanical pressure effects of endolymphatic hydrops and resultant disordered auditory physiology and symptomatology. A critical appraisal of this topic is undertaken, including a review of key histopathologic data chiefly responsible for the epiphenomenon hypothesis. Overall, a case is made that A) the preponderance of available evidence suggests endolymphatic hydrops is likely responsible for some of the auditory symptoms of Menière's disease, particularly those that can be modulated by mechanical manipulation of the basilar membrane and cochlear microphonic; B) Menière's disease can be reasonably considered part of a larger spectrum of hydropic inner ear disease that also includes some cases that lack vertigo. C) The relationship with endolymphatic hydrops sufficiently robust to consider its presence a hallmark defining feature of Menière's disease and a sensible target for diagnostic detection.
MeSH term(s)	Endolymphatic Hydrops ; Humans ; Meniere Disease ; Vertigo
Language	English
Publishing date	2019-11-19
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2036790-9
ISSN	1537-4505 ; 1531-7129
ISSN (online)	1537-4505
ISSN	1531-7129
DOI	10.1097/MAO.0000000000002502
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Book: Aging and communication

Toner, Mary Ann / Shadden, Barbara B. / Gluth, Michael B.

2011

Author's details	ed. by Mary Ann Toner ; Barbara B. Shadden ; Michael B. Gluth
Keywords	Communication Disorders ; Aged
Language	English
Size	XI, 353 S. : Ill.
Edition	2. ed.
Publisher	Pro-Ed
Publishing place	Austin, Tex
Publishing country	United States
Document type	Book
HBZ-ID	HT016998824
ISBN	978-1-4164-0494-1 ; 1-4164-0494-5
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2012 A 494	order for loan	Magazin

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Article ; Online: The Utility of Numeric Grading Scales of Middle Ear Risk in Predicting Ossiculoplasty Hearing Outcomes.

Judd, Ryan T / Imbery, Terence E / Gluth, Michael B

Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology

2021 Volume 41, Issue 10, Page(s) 1369–1378

Abstract: Objective: To assess the usefulness of numeric grading scales of middle ear risk in predicting ossiculoplasty hearing outcomes.: Study design: Retrospective review.: Setting: Tertiary care, academic medical center.: Patients: Adults and ... ...

Abstract	Objective: To assess the usefulness of numeric grading scales of middle ear risk in predicting ossiculoplasty hearing outcomes. Study design: Retrospective review. Setting: Tertiary care, academic medical center. Patients: Adults and children undergoing ossiculoplasty between May 2013 and May 2019 including: synthetic ossicular replacement prosthesis, autograft interposition, bone cement repair, and mobilization of lateral chain fixation. Intervention: Cases were scored via middle ear risk index (MERI), surgical prosthetic infection tissue eustachian tube (SPITE) method, and ossiculoplasty outcome scoring parameter (OOPS) scale. Preoperative and postoperative hearing outcomes were recorded. Main outcome measure: Statistical correlation between risk score and postoperative pure-tone average air-bone gap (PTA-ABG). Results: The 179 included cases had average pre and postoperative PTA-ABGs of 30.3dB (standard deviation [SD] 12.7) and 20.3dB (SD 11.1), respectively. Mean MERI, SPITE, and OOPS scores were 4.5 (SD 2.3), 2.8 (SD 1.7), and 3.1 (SD 1.8), respectively. Statistically significant correlations with hearing outcome were noted for all three methods (MERI r = 0.22, p = 0.003; OOPS r = 0.19, p = 0.012; SPITE r = 0.27, p < 0.001). No scale predicted poor (PTA-ABG > 30dB) outcomes; only low SPITE scores predicted excellent (PTA-ABG < 10dB) outcomes (odds ratio [OR] 0.74 [Confidence Interval: 0.57 - 0.97], p = 0.032). Conclusions: Significant weak correlations between each middle ear risk score and hearing outcomes were encountered. Although only the SPITE method predicted postoperative PTA-ABG, it was not overwhelmingly superior. Current grading scale selection may be justified by familiarity or ease of use.
MeSH term(s)	Adult ; Child ; Ear, Middle/surgery ; Hearing ; Hearing Loss, Conductive/surgery ; Humans ; Ossicular Prosthesis ; Ossicular Replacement ; Retrospective Studies ; Treatment Outcome
Language	English
Publishing date	2021-03-14
Publishing country	United States
Document type	Journal Article
ZDB-ID	2036790-9
ISSN	1537-4505 ; 1531-7129
ISSN (online)	1537-4505
ISSN	1531-7129
DOI	10.1097/MAO.0000000000002776
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Article ; Online: Rhabdomyosarcoma and other pediatric temporal bone malignancies.

Gluth, Michael B

Otolaryngologic clinics of North America

2015 Volume 48, Issue 2, Page(s) 375–390

Abstract: This article outlines the nature of temporal bone malignancy in children, particularly from the viewpoint of a surgeon. This article includes a synopsis of the presentation, workup, and management options for children affected by these uncommon tumors. ... ...

Abstract	This article outlines the nature of temporal bone malignancy in children, particularly from the viewpoint of a surgeon. This article includes a synopsis of the presentation, workup, and management options for children affected by these uncommon tumors. Particular attention is given to rhabdomyosarcoma, including an update of modern staging, risk classification, and prognosis; however, a concise review of other forms of pediatric temporal bone cancer and an overview of surgical approaches available for treatment is undertaken as well.
MeSH term(s)	Bone Neoplasms/diagnosis ; Bone Neoplasms/therapy ; Child ; Combined Modality Therapy ; Ear Neoplasms/diagnosis ; Humans ; Neoplasm Staging ; Pediatrics ; Prognosis ; Rhabdomyosarcoma/pathology ; Rhabdomyosarcoma/therapy ; Temporal Bone/pathology ; Temporal Bone/surgery
Language	English
Publishing date	2015-04
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	417489-6
ISSN	1557-8259 ; 0030-6665
ISSN (online)	1557-8259
ISSN	0030-6665
DOI	10.1016/j.otc.2014.12.010
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Article ; Online: Histopathology of the Mucosa of Eustachian Tube Orifice at the Middle Ear in Chronic Otitis Media With Effusion: Possible Insight Into Tuboplasty Failure.

Christov, Florian / Gluth, Michael B

The Annals of otology, rhinology, and laryngology

2018 Volume 127, Issue 11, Page(s) 817–822

Abstract: Introduction: Balloon dilation of the cartilaginous segment of the Eustachian tube has emerged as a means to directly augment tubal dilatory function, and this has been applied as a potential treatment for otitis media with effusion (OME). Although ... ...

Abstract	Introduction: Balloon dilation of the cartilaginous segment of the Eustachian tube has emerged as a means to directly augment tubal dilatory function, and this has been applied as a potential treatment for otitis media with effusion (OME). Although results of clinical studies involving this modality appear promising, there are still a moderate number of ears affected by OME that do not respond. The purpose of this study was to investigate the status of mucosa of the Eustachian tube at the middle ear orifice in OME as it may relate to some cases of tuboplasty failure. Methods: Twenty-three temporal bone specimens with OME were identified within an institutional archived collection. Each specimen was inspected for the presence of a fixed obstruction at the level of the Eustachian tube orifice at the protympanum. In addition, the mucosa at the tubal orifice was graded on a 4-point scale. Results: Overall, 3 cases (13%) were normal (Grade 1), 6 cases (26%) were mildly thickened (Grade 2), 11 (48%) were severely thickened (Grade 3), and 3 (13%) were severely thickened with polypoid degeneration (Grade 4). A single case was noted to have a complete fixed obstruction in the form of a mucosal web. Conclusion: In ears affected by OME, the mucosa of the Eustachian tubal orifice at the middle ear is most often severely thickened. Normal mucosa, mucosa with severe polypoid changes, or a complete fixed obstruction are possible but uncommon. The majority of specimens studied had sufficiently diseased mucosa to raise questions regarding whether thickened mucosa in the tubal orifice may act as a barrier to middle ear ventilation that would not be directly addressed by cartilaginous Eustachian tube balloon dilation.
MeSH term(s)	Chronic Disease ; Dilatation ; Eustachian Tube/pathology ; Eustachian Tube/surgery ; Humans ; Mucous Membrane/pathology ; Otitis Media with Effusion/pathology ; Treatment Failure
Language	English
Publishing date	2018-09-06
Publishing country	United States
Document type	Journal Article
ZDB-ID	120642-4
ISSN	1943-572X ; 0003-4894
ISSN (online)	1943-572X
ISSN	0003-4894
DOI	10.1177/0003489418796648
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Article: Advantages and Complications of Fisch Partial Mastoidotympanectomy for Tumors of the Retromandibular Fossa and Poststyloid Space.

Catalano, Dominic J / Gluth, Michael B

Journal of neurological surgery. Part B, Skull base

2017 Volume 78, Issue 5, Page(s) 380–384

Abstract: ... ...

Abstract	Objective
Language	English
Publishing date	2017-04-26
Publishing country	Germany
Document type	Journal Article
ZDB-ID	2654269-9
ISSN	2193-634X ; 2193-6331
ISSN (online)	2193-634X
ISSN	2193-6331
DOI	10.1055/s-0037-1602701
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Article ; Online: Frequency-Specific Analysis of Hearing Outcomes Associated with Ossiculoplasty Versus Stapedotomy.

Nguyen, Denis D / Judd, Ryan T / Imbery, Terence E / Gluth, Michael B

The Annals of otology, rhinology, and laryngology

2021 Volume 130, Issue 9, Page(s) 1010–1015

Abstract: Objective: Surgery on the ossicular chain may impact its underlying mechanical properties. This study aims to investigate comparative differences in frequency-specific hearing outcomes for ossiculoplasty versus stapedotomy.: Methods: A retrospective ... ...

Abstract	Objective: Surgery on the ossicular chain may impact its underlying mechanical properties. This study aims to investigate comparative differences in frequency-specific hearing outcomes for ossiculoplasty versus stapedotomy. Methods: A retrospective chart review was conducted on subjects who underwent ossiculoplasty with partial ossicular replacement prosthesis (PORP) or laser stapedotomy with self-crimping nitinol/fluoroplastic piston, and achieved closure of postoperative pure tone average air-bone gap (PTA-ABG) ≤ 15 dB. 45 PORP and 38 stapedotomy cases were included, with mean length of follow-up of 7.6 months. Results: The mean change in PTA-ABG was similar for the 2 procedures (-17.9 dB vs -18.1 dB, Conclusion: Both procedures achieved a similar mean change in PTA-ABG. Stapedotomy was superior to PORP at ABG closure at 1000 Hz and at 4000 Hz, with 1000 Hz the most discrepant. The exact mechanism responsible for these changes is unclear, but the specific frequencies affected suggest that differences in each procedure's respective impact on the native resonant frequency and mass load of the system could be implicated.
MeSH term(s)	Adult ; Audiometry, Pure-Tone ; Female ; Hearing Loss, Conductive/physiopathology ; Hearing Loss, Conductive/surgery ; Humans ; Male ; Middle Aged ; Ossicular Replacement/methods ; Retrospective Studies ; Stapes Surgery/methods ; Treatment Outcome ; Young Adult
Language	English
Publishing date	2021-01-29
Publishing country	United States
Document type	Comparative Study ; Journal Article
ZDB-ID	120642-4
ISSN	1943-572X ; 0003-4894
ISSN (online)	1943-572X
ISSN	0003-4894
DOI	10.1177/0003489421990164
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Article ; Online: Age-Related Change in Vestibular Ganglion Cell Populations in Individuals With Presbycusis and Normal Hearing.

Gluth, Michael B / Nelson, Erik G

Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology

2017 Volume 38, Issue 4, Page(s) 540–546

Abstract: Hypothesis: We sought to establish that the decline of vestibular ganglion cell counts uniquely correlates with spiral ganglion cell counts, cochlear hair cell counts, and hearing phenotype in individuals with presbycusis.: Background: The ... ...

Abstract	Hypothesis: We sought to establish that the decline of vestibular ganglion cell counts uniquely correlates with spiral ganglion cell counts, cochlear hair cell counts, and hearing phenotype in individuals with presbycusis. Background: The relationship between aging in the vestibular system and aging in the cochlea is a topic of ongoing investigation. Histopathologic age-related changes the vestibular system may mirror what is seen in the cochlea, but correlations with hearing phenotype and the impact of presbycusis are not well understood. Methods: Vestibular ganglion cells, spiral ganglion cells, and cochlear hair cells were counted in specimens from individuals with presbycusis and normal hearing. These were taken from within a large collection of processed human temporal bones. Correlations between histopathology and hearing phenotype were investigated. Results: Vestibular ganglion cell counts were positively correlated with spiral ganglion cell counts and cochlear hair cell counts and were negatively correlated with hearing phenotype. There was no statistical evidence on linear regression to suggest that the relationship between age and cell populations differed significantly according to whether presbycusis was present or not. Superior vestibular ganglion cells were more negatively correlated with age than inferior ganglion cells. No difference in vestibular ganglion cells was noted based on sex. Conclusion: Vestibular ganglion cell counts progressively deteriorate with age, and this loss correlates closely with changes in the cochlea, as well as hearing phenotype. However, these correlations do not appear to be unique in individuals with presbycusis as compared with those with normal hearing.
MeSH term(s)	Aged ; Aging/pathology ; Cell Count ; Cochlea/pathology ; Female ; Hair Cells, Auditory/pathology ; Hearing ; Humans ; Male ; Presbycusis/pathology ; Spiral Ganglion/pathology ; Vestibular Nerve/pathology
Language	English
Publishing date	2017-04
Publishing country	United States
Document type	Journal Article
ZDB-ID	2036790-9
ISSN	1537-4505 ; 1531-7129
ISSN (online)	1537-4505
ISSN	1531-7129
DOI	10.1097/MAO.0000000000001325
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Article ; Online: Human Superior Olivary Nucleus Neuron Populations in Subjects With Normal Hearing and Presbycusis.

Christov, Florian / Nelson, Erik G / Gluth, Michael B

The Annals of otology, rhinology, and laryngology

2018 Volume 127, Issue 8, Page(s) 527–535

Abstract: Introduction: Normative data on superior olivary nucleus neuron counts derived from human specimens are sparse, and little is known about their coherence with structure and function of the cochlea. The purpose of this study was to quantify the neuron ... ...

Abstract	Introduction: Normative data on superior olivary nucleus neuron counts derived from human specimens are sparse, and little is known about their coherence with structure and function of the cochlea. The purpose of this study was to quantify the neuron populations of the divisions of the superior olivary nucleus in human subjects with normal hearing and presbycusis and investigate potential relationships between these findings and histopathology in the cochlea and hearing phenotype Methods: Histopathologic examination of temporal bone and brainstem specimens from 13 subjects having normal hearing or presbycusis was undertaken. The following was determined for each: number and density of superior olivary nucleus and cochlear nucleus neurons, inner and outer hair cell counts, spiral ganglion cell counts, and pure tone audiometry. Results: The results demonstrate a significant relationship between cells within structures of the cochlear nucleus and the number of neurons of the medial superior olivary nucleus. No relationship between superior olivary nucleus neuron counts/density and cochlear histopathology or hearing phenotype was encountered. Conclusion: Normative data for superior olivary nucleus neuron populations are further established in the data presented in this study that includes subjects with normal hearing and also presbycusis.
MeSH term(s)	Adolescent ; Adult ; Aged ; Audiometry, Pure-Tone ; Biopsy ; Female ; Hearing/physiology ; Hearing Loss, Sensorineural/diagnosis ; Hearing Loss, Sensorineural/physiopathology ; Humans ; Male ; Middle Aged ; Presbycusis/diagnosis ; Presbycusis/physiopathology ; Spiral Ganglion/diagnostic imaging ; Spiral Ganglion/physiopathology ; Superior Olivary Complex/diagnostic imaging ; Superior Olivary Complex/physiopathology ; Young Adult
Language	English
Publishing date	2018-08
Publishing country	United States
Document type	Journal Article
ZDB-ID	120642-4
ISSN	1943-572X ; 0003-4894
ISSN (online)	1943-572X
ISSN	0003-4894
DOI	10.1177/0003489418779405
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