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  1. Book: Neuropsychology of children in Africa

    Boivin, Michael J. / Giordani, Bruno

    perspectives on risk and resilience

    (Specialty topics in pediatric neuropsychology)

    2013  

    Author's details Michael J. Boivin ... ed
    Series title Specialty topics in pediatric neuropsychology
    Keywords Afrika ; Kind ; Resilienz ; Psychosoziale Entwicklung ; Kognitive Entwicklung
    Subject Kind ; Kognition ; Denkentwicklung ; Denken ; Geistige Entwicklung ; Kindheit ; Kindesalter ; Kindschaft ; Kinder ; Widerstandsfähigkeit ; Psychische Widerstandsfähigkeit ; Psychische Widerstandskraft
    Language English
    Size XX, 347 S. : Ill., graph. Darst.
    Publisher Springer
    Publishing place New York, NY u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT017674639
    ISBN 978-1-4614-6833-2 ; 9781461468349 ; 1-4614-6833-7 ; 1461468345
    Database Catalogue ZB MED Medicine, Health

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  2. Article: New evidence for nodding disease as an autoimmune reaction to

    Boivin, Michael J

    Annals of translational medicine

    2017  Volume 5, Issue 23, Page(s) 461

    Language English
    Publishing date 2017-12-22
    Publishing country China
    Document type Editorial ; Comment
    ZDB-ID 2893931-1
    ISSN 2305-5847 ; 2305-5839
    ISSN (online) 2305-5847
    ISSN 2305-5839
    DOI 10.21037/atm.2017.09.06
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Central nervous system and neurodevelopmental outcomes of HIV + and HIV exposed children: A mini review of recent findings and lessons learned from the field.

    Glenn Fowler, Mary / Boivin, Michael J / Familiar, Itziar / Nyangoma, Betty

    Neuroscience letters

    2022  Volume 775, Page(s) 136501

    MeSH term(s) Anti-Retroviral Agents ; Central Nervous System ; Child ; Female ; HIV Infections/complications ; HIV Infections/drug therapy ; Humans ; Pregnancy ; Pregnancy Complications, Infectious
    Chemical Substances Anti-Retroviral Agents
    Language English
    Publishing date 2022-02-02
    Publishing country Ireland
    Document type Journal Article ; Review
    ZDB-ID 194929-9
    ISSN 1872-7972 ; 0304-3940
    ISSN (online) 1872-7972
    ISSN 0304-3940
    DOI 10.1016/j.neulet.2022.136501
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Is Neurodevelopmental Assessment in Early Childhood Predictive of Performance Assessed Later in Childhood and Adolescence in Sub-Saharan Africa? A Systematic Review of the Literature.

    Zoumenou, Roméo / Bodeau-Livinec, Florence / Chausseboeuf, Léa / Boivin, Michael J / Wendland, Jaqueline

    Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists

    2023  Volume 39, Issue 1, Page(s) 98–116

    Abstract: Background: Most neurodevelopmental tests used to assess child development in sub-Saharan Africa were developed in western or high-income countries, raising the question of their usefulness with African children.: Objective: This systematic review ... ...

    Abstract Background: Most neurodevelopmental tests used to assess child development in sub-Saharan Africa were developed in western or high-income countries, raising the question of their usefulness with African children.
    Objective: This systematic review identified and synthesized key findings from studies measuring development in children in Sub-Saharan Africa in early childhood and again at school age, to assess neurocognitive associations longitudinally from infancy through middle childhood.
    Methods: The study was based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses method, selecting articles referenced in the PubMed, PsycInfo, and Embase databases using the following inclusion criteria: published between 2000 and 2022, written in French or English, and presenting results dealing with the objective assessment of child's neurodevelopment. All articles were registered in the Zotero reference manager and analyzed by title, abstract, and full text.
    Results: Several of the seven selected studies confirmed that attention and working memory in infancy can predict children's neurocognitive performance, including mathematical ability, at school age. In two of the studies, children with poor mental development at 1 year of age are more likely to present with poorer behavioral development at school age, including learning difficulties in school and risk for grade repetition.
    Conclusion: Cognitive ability assessed in early childhood is strongly associated with performance at school age in cohorts of African children followed longitudinally. Even with assessments adapted cross-culturally, infants and preschoolers at risk for poor developmental outcomes can be identified to better receive strategic early interventions to enhance their development.
    MeSH term(s) Infant ; Child ; Humans ; Child, Preschool ; Adolescent ; Neuropsychological Tests ; Schools ; Africa South of the Sahara/epidemiology ; Cognition ; Child Development
    Language English
    Publishing date 2023-07-18
    Publishing country United States
    Document type Systematic Review ; Journal Article
    ZDB-ID 632972-x
    ISSN 1873-5843 ; 0887-6177
    ISSN (online) 1873-5843
    ISSN 0887-6177
    DOI 10.1093/arclin/acad051
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Attention Test Assessment from a Cluster Randomized Controlled Trial of Caregiver Training for Ugandan Preschool Children Living with Perinatal HIV.

    Rice, Micaela / Ozdemir, Sevil / Familiar-Lopez, Itziar / Arima, Ethan Godwills / Awadu, Jorem / Ojuka, Julius Caesar / Boivin, Michael J

    Developmental neuropsychology

    2023  Volume 48, Issue 8, Page(s) 361–372

    Abstract: Fifty-six Ugandan mothers/caregivers received Mediational Intervention for Sensitizing Caregivers (MISC) biweekly for one year; 46 mothers received treatment-as-usual. Preschool PHIV child attention was measured by proportion of time viewing a 7-min ... ...

    Abstract Fifty-six Ugandan mothers/caregivers received Mediational Intervention for Sensitizing Caregivers (MISC) biweekly for one year; 46 mothers received treatment-as-usual. Preschool PHIV child attention was measured by proportion of time viewing a 7-min animation (early childhood vigilance test or ECVT) at enrollment, 6 and 12 months. Analysis of covariance compared ECVT outcomes for the two intervention groups, controlling for baseline ECVT performance, age and weight-for-age z scores. Differences by trial arm were not significant at any of the three time points. MISC trial-arm children on combination ART during the study period displayed more stable ECVT scores across time points compared to controls.
    MeSH term(s) Female ; Pregnancy ; Humans ; Child, Preschool ; Caregivers/education ; Uganda ; HIV Infections ; Mothers ; Attention
    Language English
    Publishing date 2023-12-06
    Publishing country England
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 632665-1
    ISSN 1532-6942 ; 8756-5641
    ISSN (online) 1532-6942
    ISSN 8756-5641
    DOI 10.1080/87565641.2023.2280182
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Caregivers' Perspective on the Psychological Burden of Living with Children Affected by Sickle Cell Disease in Kinshasa, the Democratic Republic of Congo.

    Lelo, Patricia V M / Kitetele, Faustin Nd / Akele, Cathy E / Sam, David Lackland / Boivin, Michael J / Kashala-Abotnes, Esperance

    Children (Basel, Switzerland)

    2023  Volume 10, Issue 2

    Abstract: There is limited information on knowledge, perceptions, and management of sickle cell disease (SCD) in Africa in general and in the Democratic Republic of the Congo (DRC) in particular. This study explored knowledge, perceptions, and burden of 26 parents/ ...

    Abstract There is limited information on knowledge, perceptions, and management of sickle cell disease (SCD) in Africa in general and in the Democratic Republic of the Congo (DRC) in particular. This study explored knowledge, perceptions, and burden of 26 parents/caregivers of children with SCD in three selected hospitals in Kinshasa, DRC. We conducted a focus group with in-depth interviews with parents/caregivers of children affected with SCD. Four themes were discussed, including knowledge and perceptions, diagnosis and management, society's perceptions, and the psychosocial burden and the quality of life of the family affected by SCD. The majority of participants/caregivers felt that society, in general, had negative perceptions of, attitudes toward, and knowledge about SCD. They reported that children with sickle cell are often marginalized, ignored, and excluded from society or school. They face a number of challenges related to care, management, financial difficulties, and a lack of psychological support. The results suggest the need to promote measures and strategies to improve knowledge and management of SCD in Kinshasa, DRC.
    Language English
    Publishing date 2023-01-31
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2732685-8
    ISSN 2227-9067
    ISSN 2227-9067
    DOI 10.3390/children10020261
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: The emerging role of digital health in the management of asthma.

    Kaplan, Alan / Boivin, Michael / Bouchard, Jacques / Kim, James / Hayes, Sean / Licskai, Christopher

    Therapeutic advances in chronic disease

    2023  Volume 14, Page(s) 20406223231209329

    Abstract: The most common reasons seen for lack of asthma control include misconceptions about disease control, low controller treatment adherence, poor inhaler technique, and the resulting underuse of controllers and overuse of short-acting beta2 agonists (SABAs). ...

    Abstract The most common reasons seen for lack of asthma control include misconceptions about disease control, low controller treatment adherence, poor inhaler technique, and the resulting underuse of controllers and overuse of short-acting beta2 agonists (SABAs). Narrowing these care gaps may be achieved through well-designed patient education that considers the patient's motivation, beliefs, and capabilities regarding their asthma and its management and empowers the patient to become an active participant in treatment decisions. Digital health technologies (DHTs) and digital therapeutic (DT) devices provide new opportunities to monitor treatment behaviors, improve communication between healthcare providers and patients, and generate data that inform educational interactions. DHT and DT have been proven effective in enhancing patient self-management in other chronic conditions, particularly diabetes. Accelerated integration of DHT and DT into the management of asthma patients is facilitated by the use of digital inhalers that employ sensor technology ("smart" inhalers). These devices efficiently provide real-time feedback on controller adherence, SABA use, and inhaler technique that have the strong potential to optimize asthma control.
    Language English
    Publishing date 2023-11-17
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2554816-5
    ISSN 2040-6231 ; 2040-6223
    ISSN (online) 2040-6231
    ISSN 2040-6223
    DOI 10.1177/20406223231209329
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Early Childhood Vigilance Test (ECVT) of attention in younger HIV-exposed Ugandan children predicts Tests of Variables of Attention (TOVA) at school age.

    Familiar, Itziar / Sikorskii, Alla / Chhaya, Ronak / Weiss, Jonathan / Seffren, Victoria / Ojuka, Julius Caesar / Awadu, Jorem / Boivin, Michael J

    Neuropsychology

    2022  Volume 36, Issue 3, Page(s) 185–194

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Attention ; Child, Preschool ; Cognition/physiology ; HIV Infections/diagnosis ; HIV Infections/psychology ; Humans ; Schools ; Uganda
    Language English
    Publishing date 2022-01-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1042412-x
    ISSN 1931-1559 ; 0894-4105
    ISSN (online) 1931-1559
    ISSN 0894-4105
    DOI 10.1037/neu0000788
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: "Photo-Adrenalines": Photoswitchable β

    Sink, Alexandra / Gerwe, Hubert / Hübner, Harald / Boivin-Jahns, Valerie / Fender, Julia / Lorenz, Kristina / Gmeiner, Peter / Decker, Michael

    Chemistry (Weinheim an der Bergstrasse, Germany)

    2024  Volume 30, Issue 11, Page(s) e202303506

    Abstract: ... ...

    Abstract β
    MeSH term(s) Adrenergic Agents ; Adrenergic beta-2 Receptor Agonists/pharmacology ; Molecular Probes ; Receptors, Adrenergic, beta-2/chemistry ; Epinephrine/pharmacology ; Signal Transduction
    Chemical Substances Adrenergic Agents ; Adrenergic beta-2 Receptor Agonists ; Molecular Probes ; Receptors, Adrenergic, beta-2 ; Epinephrine (YKH834O4BH)
    Language English
    Publishing date 2024-01-11
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1478547-X
    ISSN 1521-3765 ; 0947-6539
    ISSN (online) 1521-3765
    ISSN 0947-6539
    DOI 10.1002/chem.202303506
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Neurocognitive Complications of Pediatric HIV Infections.

    Benki-Nugent, Sarah / Boivin, Michael J

    Current topics in behavioral neurosciences

    2019  Volume 50, Page(s) 147–174

    Abstract: The prevalence of cognitive impairment or learning difficulties in HIV-infected children is high despite access to antiretroviral treatment (ART). Several biological mechanisms, including latent HIV reservoir persistence in the brain, local inflammation ... ...

    Abstract The prevalence of cognitive impairment or learning difficulties in HIV-infected children is high despite access to antiretroviral treatment (ART). Several biological mechanisms, including latent HIV reservoir persistence in the brain, local inflammation within the central nervous system (CNS), disruption of neuronal function and integrity, and ongoing infiltration of activated HIV target cells to the CNS during brain development, may each dampen efficacy of ART. Development of therapeutics to target these mechanisms will be crucial, and potential candidates may include chemokine receptor antagonists. Separately, psychosocial approaches to support caregiving may leverage neuroplasticity and support brain development during critical developmental windows in spite of perinatal HIV infection. Multipronged approaches that encompass both approaches are crucial for optimizing neurodevelopmental outcomes in these extraordinarily vulnerable children. Dynamic neuropsychological assessments, such as what can be obtained with the use of computerized cognitive games intervention, may prove more sensitive to the brain/behavior benefits of ART. Dynamic neuropsychological outcomes, neuroinflammatory biomarkers, and brain development neuroprotective factors (BDNFs) may each be used to evaluate brain/behavior integrity of children in response to new treatment options.
    MeSH term(s) Anti-Retroviral Agents/therapeutic use ; Central Nervous System ; Female ; HIV Infections/complications ; HIV Infections/drug therapy ; HIV-1 ; Humans ; Pregnancy ; Virus Latency
    Chemical Substances Anti-Retroviral Agents
    Language English
    Publishing date 2019-09-16
    Publishing country Germany
    Document type Journal Article
    ISSN 1866-3370
    ISSN 1866-3370
    DOI 10.1007/7854_2019_102
    Database MEDical Literature Analysis and Retrieval System OnLINE

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