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  1. Book: Cognitive behavioral therapy in youth

    Peters, Todd E. / Freeman, Jennifer B.

    (Child and adolescent psychiatric clinics of North America ; 20,2)

    2011  

    Title variant Cognitive-behavioral therapy in youth
    Author's details guest ed. Todd E. Peters ; Jennifer B. Freeman
    Series title Child and adolescent psychiatric clinics of North America ; 20,2
    Collection
    Language English
    Size XVI S., S. 179 - 411 : graph. Darst.
    Publisher Saunders an imprint of Elsevier
    Publishing place Philadelphia, Pa
    Publishing country United States
    Document type Book
    HBZ-ID HT016808755
    ISBN 978-1-4557-0428-6 ; 1-4557-0428-8
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

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    Se 1345 -20,2- verfügbar in Königswinter Königswinter

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  2. Article ; Online: Developmental Surveillance: Context Matters.

    Freeman, Brandi / Walton, Jennifer

    Pediatrics

    2024  Volume 153, Issue 4

    MeSH term(s) Male ; Female ; Humans ; Sexual Maturation
    Language English
    Publishing date 2024-03-28
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 207677-9
    ISSN 1098-4275 ; 0031-4005
    ISSN (online) 1098-4275
    ISSN 0031-4005
    DOI 10.1542/peds.2023-064452
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Author Correction: Selective modulation of the androgen receptor AF2 domain rescues degeneration in spinal bulbar muscular atrophy.

    Badders, Nisha M / Korff, Ane / Miranda, Helen C / Vuppala, Pradeep K / Smith, Rebecca B / Winborn, Brett J / Quemin, Emmanuelle R / Sopher, Bryce L / Dearman, Jennifer / Messing, James / Kim, Nam Chul / Moore, Jennifer / Freibaum, Brian D / Kanagaraj, Anderson P / Fan, Baochang / Tillman, Heather / Chen, Ping-Chung / Wang, Yingzhe / Freeman, Burgess B /
    Li, Yimei / Kim, Hong Joo / La Spada, Albert R / Taylor, J Paul

    Nature medicine

    2024  Volume 30, Issue 3, Page(s) 909–910

    Language English
    Publishing date 2024-03-25
    Publishing country United States
    Document type Published Erratum
    ZDB-ID 1220066-9
    ISSN 1546-170X ; 1078-8956
    ISSN (online) 1546-170X
    ISSN 1078-8956
    DOI 10.1038/s41591-023-02778-7
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  4. Article ; Online: Precision Implementation: An Approach to Mechanism Testing in Implementation Research.

    Frank, Hannah E / Kemp, Joshua / Benito, Kristen G / Freeman, Jennifer B

    Administration and policy in mental health

    2022  Volume 49, Issue 6, Page(s) 1084–1094

    Abstract: Advancing mechanism-focused research in implementation science is a priority given its potential to improve tailoring and efficiency of implementation strategies. Experimental therapeutics, or experimental medicine, offers an approach for mechanism ... ...

    Abstract Advancing mechanism-focused research in implementation science is a priority given its potential to improve tailoring and efficiency of implementation strategies. Experimental therapeutics, or experimental medicine, offers an approach for mechanism testing that has been promoted by the NIH Science of Behavior Change and endorsed by the National Institute for Mental Health. This approach has been applied across the translational spectrum - with initial applications to biological research and more recent applications to psychosocial treatment development research. We describe further advancement of experimental therapeutics along the translational spectrum and describe how it is ideally suited to inform precision experimental tests of implementation strategy mechanisms, which we term precision implementation. Such an approach to mechanism testing will allow for identification of causal dose-response relationships between implementation strategies, presumed mechanisms, and implementation outcomes. We discuss the tension between the scientific rigor required to conduct mechanism-focused research using experimental therapeutics and the "real world" conditions in which implementation research takes place. We provide a series of example studies that show "beginning to end" application of this framework in research focused on provider implementation of an evidence-based intervention in routine clinical care settings.
    MeSH term(s) Humans ; Implementation Science ; Mental Health
    Language English
    Publishing date 2022-09-27
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 1025319-1
    ISSN 1573-3289 ; 0894-587X
    ISSN (online) 1573-3289
    ISSN 0894-587X
    DOI 10.1007/s10488-022-01218-x
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  5. Article ; Online: Expanding the reach of evidence-based mental health interventions to private practice: Qualitative assessment using a policy ecology framework.

    Frank, Hannah E / Milgram, Lauren / Freeman, Jennifer B / Benito, Kristen G

    Frontiers in health services

    2022  Volume 2, Page(s) 892294

    Abstract: Background: Evidence-based interventions (EBIs) for mental health disorders are underutilized in routine clinical practice. Exposure therapy for anxiety disorders is one particularly difficult-to-implement EBI that has robust empirical support. Previous ...

    Abstract Background: Evidence-based interventions (EBIs) for mental health disorders are underutilized in routine clinical practice. Exposure therapy for anxiety disorders is one particularly difficult-to-implement EBI that has robust empirical support. Previous research has examined EBI implementation determinants in publicly funded mental health settings, but few studies have examined EBI implementation determinants in private practice settings. Private practice clinicians likely face unique barriers to implementation, including setting-specific contextual barriers to EBI use. The policy ecology framework considers broad systemic determinants, including organizational, regulatory, social, and political contexts, which are likely relevant to EBI implementation in private practice settings but have not been examined in prior research.
    Methods: Qualitative interviews were conducted to assess private practice clinicians' perceptions of EBI implementation determinants using the policy ecology framework. Clinicians were asked about implementing mental health EBIs broadly and exposure therapy specifically. Mixed methods analyses compared responses from clinicians working in solo vs. group private practice and clinicians who reported high vs. low organizational support for exposure therapy.
    Results: Responses highlight several barriers and facilitators to EBI implementation in private practice. Examples include determinants related to organizational support (e.g., colleagues using EBIs), payer restrictions (e.g., lack of reimbursement for longer sessions), fiscal incentives (e.g., payment for attending training), and consumer demand for EBIs. There were notable differences in barriers faced by clinicians who work in group private practices compared to those working in solo practices. Solo private practice clinicians described ways in which their practice setting limits their degree of colleague support (e.g., for consultation or exposure therapy planning), while also allowing for flexibility (e.g., in their schedules and practice location) that may not be available to clinicians in group practice.
    Conclusions: Using the policy ecology framework provides a broad understanding of contextual factors that impact private practice clinicians' use of EBIs, including exposure therapy. Findings point to potential implementation strategies that may address barriers that are unique to clinicians working in private practice.
    Language English
    Publishing date 2022-07-22
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2813-0146
    ISSN (online) 2813-0146
    DOI 10.3389/frhs.2022.892294
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: A Quality Analysis of Bony Specimens for Optimal Ethylenediaminetetraacetic Acid (EDTA) Decalcification.

    Craig, J Cody / Freeman, Michelle / Walton, Schaundra / Rogers, Demonica / Mehrad, Mitra / Gordetsky, Jennifer B

    International journal of surgical pathology

    2022  Volume 30, Issue 8, Page(s) 853–860

    Abstract: Introduction: ...

    Abstract Introduction:
    MeSH term(s) Humans ; Edetic Acid/pharmacology ; Bone and Bones ; Formaldehyde ; Tibia ; Femur/surgery
    Chemical Substances Edetic Acid (9G34HU7RV0) ; Formaldehyde (1HG84L3525)
    Language English
    Publishing date 2022-03-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1336393-1
    ISSN 1940-2465 ; 1066-8969
    ISSN (online) 1940-2465
    ISSN 1066-8969
    DOI 10.1177/10668969221088877
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: "Pick your team wisely": A case study of a long-standing research-practice partnership.

    Melton, Theresa N / Agans, Jennifer P / Lawhon, Ben / Mateer, Timothy J / Freeman, Stephanie / Taff, B Derrick

    Evaluation and program planning

    2022  Volume 95, Page(s) 102169

    Abstract: Research-practice partnerships (RPP) provide opportunities to connect researchers, practitioners, and/or community development professionals in meaningful ways, thereby improving the quality of research, evaluation, and practice in communities. Yet, ... ...

    Abstract Research-practice partnerships (RPP) provide opportunities to connect researchers, practitioners, and/or community development professionals in meaningful ways, thereby improving the quality of research, evaluation, and practice in communities. Yet, there is still much to learn about how successful partnerships between researchers and practitioners develop. Historically, research on this topic has emphasized challenges that prevent RPP from developing to their highest potential, with limited information available on ways to promote RPP and how to ensure RPP are mutually beneficial for participants. However, research on partnerships more generally, such as multisector partnerships, can contribute meaningfully to the RPP field. We present an in-depth case study on a successful, long-term partnership. In this study, we pull from the broader partnership literature to explore contexts that are likely to promote partnerships, as well as the activities that can strengthen RPP. Findings focus on addressing ways to promote RPP and highlight the importance of preexisting factors, such as a culture that values both researcher and practitioner expertise, history, and chemistry between partners. Additionally, non-professional space and time, productive disagreements, clear but evolving roles, and shared power were found to strengthen collaboration within the partnership. Specific advice for anyone considering joining an RPP is also discussed.
    MeSH term(s) Humans ; Cooperative Behavior ; Program Evaluation ; Research Personnel
    Language English
    Publishing date 2022-09-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 2013444-7
    ISSN 1873-7870 ; 0149-7189
    ISSN (online) 1873-7870
    ISSN 0149-7189
    DOI 10.1016/j.evalprogplan.2022.102169
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  8. Book: The ketogenic diet

    Freeman, John M. / Freeman, Jennifer B. / Kelly, Millicent T.

    a treatment for epilepsy

    2000  

    Author's details [John M. Freeman ; Jennifer B. Freeman ; Millicent T. Kelly]
    Language English
    Size XIX, 236 S.
    Edition 3. ed.
    Publisher Demos
    Publishing place New York
    Publishing country United States
    Document type Book
    HBZ-ID HT012845557
    ISBN 1-888799-39-0 ; 978-1-888799-39-2
    Database Catalogue ZB MED Medicine, Health

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    2001 A 44 order for loan Magazin

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  9. Article ; Online: Systematic Literature Review of Health-Related Quality-of-Life Measures for Caregivers of Older Adult Trauma Patients.

    Haines, Krista / Lumpkin, Stephanie T / Grisel, Braylee / Kaur, Kavneet / Cantrell, Sarah / Freeman, Jennifer / Tripoli, Todd / Gallagher, Scott / Agarwal, Suresh / Cox, Christopher E / Schmader, Kenneth / Reeve, Bryce B

    The Journal of surgical research

    2024  Volume 297, Page(s) 47–55

    Abstract: Introduction: As the older adult population increases, hospitals treat more older adults with injuries. After leaving, these patients suffer from decreased mobility and independence, relying on care from others. Family members often assume this ... ...

    Abstract Introduction: As the older adult population increases, hospitals treat more older adults with injuries. After leaving, these patients suffer from decreased mobility and independence, relying on care from others. Family members often assume this responsibility, mostly informally and unpaid. Caregivers of other older adult populations have increased stress and decreased caregiver-related quality of life (CRQoL). Validated CRQoL measures are essential to capture their unique experiences. Our objective was to review existing CRQoL measures and their validity in caregivers of older adult trauma patients.
    Methods: A professional librarian searched published literature from the inception of databases through August 12, 2022 in MEDLINE (via PubMed), Embase (via Elsevier), and CINAHL Complete (via EBSCO). We identified 1063 unique studies of CRQoL in caregivers for adults with injury and performed a systematic review following COnsensus-based Standards for the selection of health Measurement Instruments guidelines for CRQoL measures.
    Results: From the 66 studies included, we identified 54 health-related quality-of-life measures and 60 domains capturing caregiver-centered concerns. The majority (83%) of measures included six or fewer CRQoL content domains. Six measures were used in caregivers of older adults with single-system injuries. There were no validated CRQoL measures among caregivers of older adult trauma patients with multisystem injuries.
    Conclusions: While many measures exist to assess healthcare-related quality of life, few, if any, adequately assess concerns among caregivers of older adult trauma patients. We found that CRQoL domains, including mental health, emotional health, social functioning, and relationships, are most commonly assessed among caregivers. Future measures should focus on reliability and validity in this specific population to guide interventions.
    MeSH term(s) Humans ; Aged ; Quality of Life/psychology ; Caregivers/psychology ; Reproducibility of Results ; Mental Health
    Language English
    Publishing date 2024-03-01
    Publishing country United States
    Document type Systematic Review ; Journal Article
    ZDB-ID 80170-7
    ISSN 1095-8673 ; 0022-4804
    ISSN (online) 1095-8673
    ISSN 0022-4804
    DOI 10.1016/j.jss.2024.01.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Developmental Pb exposure increases AD risk via altered intracellular Ca

    Xie, Junkai / Wu, Shichen / Szadowski, Hailey / Min, Sehong / Yang, Yang / Bowman, Aaron B / Rochet, Jean-Christophe / Freeman, Jennifer L / Yuan, Chongli

    The Journal of biological chemistry

    2023  Volume 299, Issue 8, Page(s) 105023

    Abstract: Exposure to environmental chemicals such as lead (Pb) during vulnerable developmental periods can result in adverse health outcomes later in life. Human cohort studies have demonstrated associations between developmental Pb exposure and Alzheimer's ... ...

    Abstract Exposure to environmental chemicals such as lead (Pb) during vulnerable developmental periods can result in adverse health outcomes later in life. Human cohort studies have demonstrated associations between developmental Pb exposure and Alzheimer's disease (AD) onset in later life which were further corroborated by findings from animal studies. The molecular pathway linking developmental Pb exposure and increased AD risk, however, remains elusive. In this work, we used human iPSC-derived cortical neurons as a model system to study the effects of Pb exposure on AD-like pathogenesis in human cortical neurons. We exposed neural progenitor cells derived from human iPSC to 0, 15, and 50 ppb Pb for 48 h, removed Pb-containing medium, and further differentiated them into cortical neurons. Immunofluorescence, Western blotting, RNA-sequencing, ELISA, and FRET reporter cell lines were used to determine changes in AD-like pathogenesis in differentiated cortical neurons. Exposing neural progenitor cells to low-dose Pb, mimicking a developmental exposure, can result in altered neurite morphology. Differentiated neurons exhibit altered calcium homeostasis, synaptic plasticity, and epigenetic landscape along with elevated AD-like pathogenesis markers, including phosphorylated tau, tau aggregates, and Aβ42/40. Collectively, our findings provide an evidence base for Ca dysregulation caused by developmental Pb exposure as a plausible molecular mechanism accounting for increased AD risk in populations with developmental Pb exposure.
    MeSH term(s) Animals ; Humans ; Alzheimer Disease/genetics ; Alzheimer Disease/pathology ; Homeostasis ; Induced Pluripotent Stem Cells/pathology ; Lead/toxicity ; Neurons/pathology
    Chemical Substances Lead (2P299V784P)
    Language English
    Publishing date 2023-07-07
    Publishing country United States
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
    ZDB-ID 2997-x
    ISSN 1083-351X ; 0021-9258
    ISSN (online) 1083-351X
    ISSN 0021-9258
    DOI 10.1016/j.jbc.2023.105023
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