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  1. Article ; Online: Inflammation contributes to cardiovascular risk in patients receiving statin therapy.

    Tardif, Jean-Claude / Samuel, Michelle

    Lancet (London, England)

    2023  Volume 401, Issue 10384, Page(s) 1245–1247

    MeSH term(s) Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/adverse effects ; Cardiovascular Diseases/epidemiology ; Cardiovascular Diseases/prevention & control ; Risk Factors ; Inflammation/drug therapy ; Heart Disease Risk Factors
    Chemical Substances Hydroxymethylglutaryl-CoA Reductase Inhibitors
    Language English
    Publishing date 2023-03-06
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0023-7507 ; 0140-6736
    ISSN (online) 1474-547X
    ISSN 0023-7507 ; 0140-6736
    DOI 10.1016/S0140-6736(23)00454-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Inhibition of the Mechanistic Target of Rapamycin in Acute Myocardial Infarction.

    Tardif, Jean-Claude / Thorin, Eric

    Journal of the American College of Cardiology

    2022  Volume 80, Issue 19, Page(s) 1815–1817

    MeSH term(s) Humans ; Sirolimus/pharmacology ; Sirolimus/therapeutic use ; Myocardial Infarction/drug therapy ; Drug-Eluting Stents ; Percutaneous Coronary Intervention ; Treatment Outcome ; ST Elevation Myocardial Infarction
    Chemical Substances Sirolimus (W36ZG6FT64)
    Language English
    Publishing date 2022-11-02
    Publishing country United States
    Document type Editorial ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 605507-2
    ISSN 1558-3597 ; 0735-1097
    ISSN (online) 1558-3597
    ISSN 0735-1097
    DOI 10.1016/j.jacc.2022.08.796
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 196: Show issues

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  3. Article ; Online: Lessons learned from large Cardiovascular Outcome Trials targeting inflammation in cardiovascular disease (CANTOS, CIRT, COLCOT and LoDoCo2).

    Samuel, Michelle / Tardif, Jean-Claude

    Future cardiology

    2021  Volume 17, Issue 3, Page(s) 411–414

    MeSH term(s) Atherosclerosis ; Cardiovascular Diseases ; Colchicine ; Humans ; Inflammation
    Chemical Substances Colchicine (SML2Y3J35T)
    Language English
    Publishing date 2021-03-09
    Publishing country England
    Document type Editorial ; Research Support, Non-U.S. Gov't
    ZDB-ID 2274267-0
    ISSN 1744-8298 ; 1479-6678
    ISSN (online) 1744-8298
    ISSN 1479-6678
    DOI 10.2217/fca-2021-0027
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  4. Article ; Online: Initiation of low-dose colchicine early after myocardial infarction.

    Bouabdallaoui, Nadia / Tardif, Jean-Claude

    European heart journal

    2021  Volume 42, Issue 28, Page(s) 2798–2799

    MeSH term(s) C-Reactive Protein ; Cognition ; Colchicine ; Humans ; Myocardial Infarction/drug therapy
    Chemical Substances C-Reactive Protein (9007-41-4) ; Colchicine (SML2Y3J35T)
    Language English
    Publishing date 2021-01-31
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 603098-1
    ISSN 1522-9645 ; 0195-668X
    ISSN (online) 1522-9645
    ISSN 0195-668X
    DOI 10.1093/eurheartj/ehab038
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Repurposing Colchicine for Heart Disease.

    Bouabdallaoui, Nadia / Tardif, Jean-Claude

    Annual review of pharmacology and toxicology

    2021  Volume 62, Page(s) 121–129

    Abstract: Colchicine is one of the most ancient medications still prescribed. It is extracted from ... ...

    Abstract Colchicine is one of the most ancient medications still prescribed. It is extracted from the
    MeSH term(s) Atrial Fibrillation/drug therapy ; Colchicine/pharmacology ; Colchicine/therapeutic use ; Coronary Artery Disease/drug therapy ; Humans ; Inflammation/drug therapy ; Pericarditis/drug therapy
    Chemical Substances Colchicine (SML2Y3J35T)
    Language English
    Publishing date 2021-09-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 196587-6
    ISSN 1545-4304 ; 0362-1642
    ISSN (online) 1545-4304
    ISSN 0362-1642
    DOI 10.1146/annurev-pharmtox-052120-020445
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Pharmacogenetics-guided dalcetrapib therapy after an acute coronary syndrome.

    Tardif, Jean-Claude / Pfeffer, Marc A / Dubé, Marie-Pierre

    European heart journal

    2022  

    Language English
    Publishing date 2022-11-15
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 603098-1
    ISSN 1522-9645 ; 0195-668X
    ISSN (online) 1522-9645
    ISSN 0195-668X
    DOI 10.1093/eurheartj/ehac644
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  7. Article ; Online: Colchicine in the Management of Acute and Chronic Coronary Artery Disease.

    Bouabdallaoui, Nadia / Tardif, Jean-Claude

    Current cardiology reports

    2021  Volume 23, Issue 9, Page(s) 120

    Abstract: Purpose of review: Inflammation is involved in the initiation, progression, and destabilization of atherosclerosis. Anti-inflammatory strategies aimed at reducing residual cardiovascular (CV) risk have gained increasing interest in addition to the ... ...

    Abstract Purpose of review: Inflammation is involved in the initiation, progression, and destabilization of atherosclerosis. Anti-inflammatory strategies aimed at reducing residual cardiovascular (CV) risk have gained increasing interest in addition to the traditional management of risk factors. Colchicine is a potent anti-inflammatory therapy that affects the inflammasome and other targets. We will herein review the most recent evidence regarding the usefulness of colchicine in patients with coronary artery disease (CAD).
    Recent findings: Colchicine has recently been repurposed from its traditional use to a number of CV indications. The landmark COLCOT and LoDoCo2 trials have demonstrated that long-term use of colchicine was associated with a reduced rate of CV events in both acute and chronic presentations of CAD, with an overall good safety profile. Colchicine is emerging as a valuable, safe, and cost-effective therapy in addition to standard of care for the prevention of atherothrombotic events in CAD.
    MeSH term(s) Anti-Inflammatory Agents/therapeutic use ; Atherosclerosis/drug therapy ; Colchicine/therapeutic use ; Coronary Artery Disease/drug therapy ; Humans ; Myocardial Infarction/drug therapy
    Chemical Substances Anti-Inflammatory Agents ; Colchicine (SML2Y3J35T)
    Language English
    Publishing date 2021-07-16
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2055373-0
    ISSN 1534-3170 ; 1523-3782
    ISSN (online) 1534-3170
    ISSN 1523-3782
    DOI 10.1007/s11886-021-01560-w
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  8. Article ; Online: Inflammation in heart failure: pathophysiology and therapeutic strategies.

    Boulet, Jacinthe / Sridhar, Vikas S / Bouabdallaoui, Nadia / Tardif, Jean-Claude / White, Michel

    Inflammation research : official journal of the European Histamine Research Society ... [et al.

    2024  

    Abstract: A role for inflammation in the development and progression of heart failure (HF) has been proposed for decades. Multiple studies have demonstrated the potential involvement of several groups of cytokines and chemokines in acute and chronic HF, though ... ...

    Abstract A role for inflammation in the development and progression of heart failure (HF) has been proposed for decades. Multiple studies have demonstrated the potential involvement of several groups of cytokines and chemokines in acute and chronic HF, though targeting these pathways in early therapeutic trials have produced mixed results. These studies served to highlight the complexity and nuances of how pro-inflammatory pathways contribute to the pathogenesis of HF. More recent investigations have highlighted how inflammation may play distinct roles based on HF syndrome phenotypes, findings that may guide the development of novel therapies. In this review, we propose a contemporary update on the role of inflammation mediated by the innate and adaptive immune systems with HF, highlighting differences that exist across the ejection fraction spectrum. This will specifically be looked at through the lens of established and novel biomarkers of inflammation. Subsequently, we review how improvements in inflammatory pathways may mediate clinical benefits of existing guideline-directed medical therapies for HF, as well as future therapies in the pipeline targeting HF and inflammation.
    Language English
    Publishing date 2024-03-28
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 1221794-3
    ISSN 1420-908X ; 1023-3830
    ISSN (online) 1420-908X
    ISSN 1023-3830
    DOI 10.1007/s00011-023-01845-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 675: Show issues Location:
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  9. Book: Antioxidants and cardiovascular disease

    Tardif, Jean-Claude

    (Developments in cardiovascular medicine ; 233)

    2000  

    Author's details ed. by Jean-Claude Tardif
    Series title Developments in cardiovascular medicine ; 233
    Collection
    Keywords Kardiovaskuläre Krankheit ; Antioxidans
    Subject Oxidationsinhibitor ; Antioxygen ; Herz-Kreislauf-Krankheit ; Herz-Kreislauf-Erkrankung ; Kardiovaskuläres System ; Cardiovasculäre Krankheit ; Kardiovaskuläre Krankheiten
    Language English
    Size XII, 258 S. : Ill., graph. Darst.
    Publisher Kluwer Acad. Publ
    Publishing place Dordrecht u.a.
    Publishing country Netherlands
    Document type Book
    HBZ-ID HT012840830
    ISBN 0-7923-6564-X ; 978-0-7923-6564-8
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2000 A 4458 order for loan Magazin

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  10. Article ; Online: Colchicine for Secondary Cardiovascular Prevention in Coronary Disease.

    Roubille, François / Tardif, Jean-Claude

    Circulation

    2020  Volume 142, Issue 20, Page(s) 1901–1904

    MeSH term(s) Colchicine/adverse effects ; Coronary Artery Disease ; Humans ; Secondary Prevention
    Chemical Substances Colchicine (SML2Y3J35T)
    Language English
    Publishing date 2020-11-16
    Publishing country United States
    Document type Editorial ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 80099-5
    ISSN 1524-4539 ; 0009-7322 ; 0069-4193 ; 0065-8499
    ISSN (online) 1524-4539
    ISSN 0009-7322 ; 0069-4193 ; 0065-8499
    DOI 10.1161/CIRCULATIONAHA.120.051240
    Database MEDical Literature Analysis and Retrieval System OnLINE

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