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  1. Article ; Online: BK virus nephropathy in non-renal solid organ transplant recipients: Are we looking hard enough?

    Mallavarapu, Ravi K / Sanoff, Scott L / Howell, David N / Roberts, John K

    Clinical transplantation

    2021  Volume 35, Issue 5, Page(s) e14265

    Abstract: We retrospectively examined the clinical characteristics, pathological features, and outcomes of BK viremia and nephropathy in a population of non-renal solid organ transplant patients (NRSOT) referred for outpatient nephrology consultation over a period ...

    Abstract We retrospectively examined the clinical characteristics, pathological features, and outcomes of BK viremia and nephropathy in a population of non-renal solid organ transplant patients (NRSOT) referred for outpatient nephrology consultation over a period of 5 years. In the entire cohort of liver, heart, and lung transplant recipients referred to this clinic, 14% percent were found to have BK viremia with a median peak serum BK viral load of 35 500 copies/ml (range 250 to 21 100 000 copies/ml). BK viremia resolved in six of the seventeen patients (35%). Four out of five patients biopsied showed BK virus (BKV) nephropathy. Eleven out of seventeen patients with BK viremia developed advanced (stage 4 or 5) chronic kidney disease. Four patients developed rejection of their solid organ transplant within the first year post detection of BK viremia after immunosuppression reduction. We conclude that a multi-center study is required to evaluate whether implementation of a systematic BK screening program would be effective in early detection and management of this problem in the NRSOT population.
    MeSH term(s) BK Virus ; Humans ; Organ Transplantation ; Polyomavirus Infections ; Retrospective Studies ; Transplant Recipients ; Tumor Virus Infections
    Language English
    Publishing date 2021-03-06
    Publishing country Denmark
    Document type Journal Article
    ZDB-ID 639001-8
    ISSN 1399-0012 ; 0902-0063
    ISSN (online) 1399-0012
    ISSN 0902-0063
    DOI 10.1111/ctr.14265
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    Zs.A 2204: Show issues Location:
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  2. Article ; Online: Multigenerational effects of TiO

    Vidane Arachchige Chamila Samarasinghe, Samarasinghe / Krishnan, Kannan / John Aitken, Robert / Naidu, Ravi / Megharaj, Mallavarapu

    Environmental pollution (Barking, Essex : 1987)

    2023  Volume 336, Page(s) 122376

    Abstract: Nanoparticles have gained considerable attention as one of the pollutants released into the environment through consumer products. This study describes the sub-chronic and generational effects of ... ...

    Abstract Nanoparticles have gained considerable attention as one of the pollutants released into the environment through consumer products. This study describes the sub-chronic and generational effects of TiO
    Language English
    Publishing date 2023-08-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 280652-6
    ISSN 1873-6424 ; 0013-9327 ; 0269-7491
    ISSN (online) 1873-6424
    ISSN 0013-9327 ; 0269-7491
    DOI 10.1016/j.envpol.2023.122376
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  3. Article ; Online: Doctor, my breathing is better when I lie down.

    Mallavarapu, Ravi K / Garimella, Prasad S

    Journal of hospital medicine

    2009  Volume 4, Issue 2, Page(s) E1–2

    MeSH term(s) Aged ; Angiography ; Arteriovenous Malformations/complications ; Arteriovenous Malformations/surgery ; Dyspnea/diagnostic imaging ; Dyspnea/etiology ; Female ; Humans ; Pulmonary Artery/abnormalities ; Pulmonary Artery/diagnostic imaging ; Pulmonary Surgical Procedures ; Pulmonary Veins/abnormalities ; Pulmonary Veins/diagnostic imaging ; Supine Position/physiology ; Tomography, X-Ray Computed
    Language English
    Publishing date 2009-02
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2233783-0
    ISSN 1553-5606 ; 1553-5592
    ISSN (online) 1553-5606
    ISSN 1553-5592
    DOI 10.1002/jhm.377
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    Zs.MO 542: Show issues

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  4. Article ; Online: Purification and characterization of a novel fenamiphos hydrolysing enzyme from Microbacterium esteraromaticum MM1.

    Logeshwaran, Panneerselvan / Krishnan, Kannan / Naidu, Ravi / Megharaj, Mallavarapu

    Chemosphere

    2020  Volume 252, Page(s) 126549

    Abstract: Fenamiphos is a neurotoxic organophosphorus pesticide used widely to control pests of crops. Fenamiphos and its toxic oxidation products have been detected in surface and groundwaters. A novel enzyme capable of hydrolysing P-O-C bond of fenamiphos is ... ...

    Abstract Fenamiphos is a neurotoxic organophosphorus pesticide used widely to control pests of crops. Fenamiphos and its toxic oxidation products have been detected in surface and groundwaters. A novel enzyme capable of hydrolysing P-O-C bond of fenamiphos is purified from Microbacterium esteraromaticum MM1 total cellular protein using a combination of methods. The purified fenamiphos hydrolysing enzyme (FHE) was identified as enolase (phosphopyruvate hydratase), a housekeeping enzyme with molecular mass and pI value of 45 kDa and 4.5, respectively. The optimum pH and temperature for the activity of the FHE are 7 and 25 °C, respectively. We studied the influence of metal ions and inhibitors on the enzyme activity. The enzyme was strongly activated by Mg
    MeSH term(s) Actinobacteria/enzymology ; Actinomycetales ; Hydrogen-Ion Concentration ; Hydrolysis ; Kinetics ; Organophosphorus Compounds/metabolism ; Oxidation-Reduction ; Pesticides
    Chemical Substances Organophosphorus Compounds ; Pesticides ; fenamiphos (H4NO3L2HBE)
    Language English
    Publishing date 2020-03-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 120089-6
    ISSN 1879-1298 ; 0045-6535 ; 0366-7111
    ISSN (online) 1879-1298
    ISSN 0045-6535 ; 0366-7111
    DOI 10.1016/j.chemosphere.2020.126549
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    Zs.A 2540: Show issues Location:
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  5. Article ; Online: Pneumatocele complicating acute hydrocarbon pneumonitis.

    Mallavarapu, Ravi K / Katner, Harold P

    Clinical toxicology (Philadelphia, Pa.)

    2008  Volume 46, Issue 9, Page(s) 911

    Abstract: We present the radiological images and clinical summary of a patient with hydrocarbon ingestion and aspiration complicated by the development of a large pneumatocele. ...

    Abstract We present the radiological images and clinical summary of a patient with hydrocarbon ingestion and aspiration complicated by the development of a large pneumatocele.
    MeSH term(s) Adult ; Humans ; Hydrocarbons/poisoning ; Inhalation Exposure ; Lung Diseases/chemically induced ; Lung Diseases/diagnostic imaging ; Male ; Pneumonia, Aspiration/chemically induced ; Pneumonia, Aspiration/diagnostic imaging ; Tomography, X-Ray Computed
    Chemical Substances Hydrocarbons
    Language English
    Publishing date 2008-11
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 204476-6
    ISSN 1556-9519 ; 0009-9309 ; 0731-3810 ; 1556-3650
    ISSN (online) 1556-9519
    ISSN 0009-9309 ; 0731-3810 ; 1556-3650
    DOI 10.1080/15563650802266501
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    Zs.B 419: Show issues Location:
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  6. Article ; Online: Incarcerated umbilical hernia after transjugular intrahepatic portosystemic shunt procedure for refractory ascites.

    Mallavarapu, Ravi K / Grimsley, Edwin W

    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

    2007  Volume 5, Issue 9, Page(s) A26

    MeSH term(s) Ascites/surgery ; Diagnosis, Differential ; Female ; Hepatitis C, Chronic/complications ; Hernia, Umbilical/diagnosis ; Hernia, Umbilical/etiology ; Hernia, Umbilical/surgery ; Humans ; Liver Cirrhosis/complications ; Middle Aged ; Portasystemic Shunt, Transjugular Intrahepatic/adverse effects ; Postoperative Complications/etiology
    Language English
    Publishing date 2007-09
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2119789-1
    ISSN 1542-7714 ; 1542-3565
    ISSN (online) 1542-7714
    ISSN 1542-3565
    DOI 10.1016/j.cgh.2007.07.018
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    Zs.A 5836: Show issues Location:
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  7. Article: Three-dimensional transthoracic echocardiographic assessment of aortic stenosis and regurgitation.

    Mallavarapu, Ravi K / Nanda, Navin C

    Cardiology clinics

    2007  Volume 25, Issue 2, Page(s) 327–334

    Abstract: Color-guided continuous-wave Doppler has important limitations in the assessment of aortic stenosis (AS) and aortic regurgitation (AR). This article outlines the limitations of conventional echocardiographic methods and describes the three-dimensional ... ...

    Abstract Color-guided continuous-wave Doppler has important limitations in the assessment of aortic stenosis (AS) and aortic regurgitation (AR). This article outlines the limitations of conventional echocardiographic methods and describes the three-dimensional echocardiographic assessment of AS and AR.
    MeSH term(s) Aortic Valve Insufficiency/diagnostic imaging ; Aortic Valve Insufficiency/physiopathology ; Aortic Valve Stenosis/diagnostic imaging ; Aortic Valve Stenosis/physiopathology ; Echocardiography, Doppler, Color/methods ; Humans ; Reproducibility of Results ; Ventricular Function, Left/physiology
    Language English
    Publishing date 2007-05
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 1196385-2
    ISSN 1558-2264 ; 0733-8651
    ISSN (online) 1558-2264
    ISSN 0733-8651
    DOI 10.1016/j.ccl.2007.06.005
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  8. Article: Unresolved complex mixtures of petroleum hydrocarbons in the environment: An overview of ecological effects and remediation approaches

    Ramadass, Kavitha / Kuppusamy, Saranya / Venkateswarlu, Kadiyala / Naidu, Ravi / Megharaj, Mallavarapu

    Critical reviews in environmental science and technology. 2021 Oct. 22, v. 51, no. 23

    2021  

    Abstract: Unresolved complex mixtures (UCMs) of hydrocarbons are the pollutants of serious concern commonly occurring in most of the environments contaminated with petroleum hydrocarbons. UCMs constitute a relatively unidentified group of compounds compared to the ...

    Abstract Unresolved complex mixtures (UCMs) of hydrocarbons are the pollutants of serious concern commonly occurring in most of the environments contaminated with petroleum hydrocarbons. UCMs constitute a relatively unidentified group of compounds compared to the well-resolved hydrocarbons that could easily be identified by the modern chromatographic methods. UCMs that accumulate in the environment cause several toxicological effects of ecological significance, and indirectly affect the human health. Despite decades-long efforts to provide adequate information in this area of research, the fate and environmental impacts of UCMs of petroleum hydrocarbons are poorly understood. Techniques for extraction and analysis of UCMs in the environment are very important in their identification and quantification. Also, remediation of toxic UCMs of petroleum hydrocarbons is all the more essential. In fact, UCMs are often neglected in the risk assessments due to lack of proper identification methods and toxicity data. This critical review presents an overview of our current knowledge on the environmental occurrence, sources, separation, and identification methods for UCMs. The ecological toxicity of UCMs toward the biota and the strategies for remediation of the environments contaminated with UCMs have also been discussed in detail.
    Keywords chromatography ; ecotoxicology ; human health ; petroleum ; remediation ; risk ; technology ; toxicity
    Language English
    Dates of publication 2021-1022
    Size p. 2872-2894.
    Publishing place Taylor & Francis
    Document type Article
    ZDB-ID 2030115-7
    ISSN 1547-6537 ; 1064-3389
    ISSN (online) 1547-6537
    ISSN 1064-3389
    DOI 10.1080/10643389.2020.1813066
    Database NAL-Catalogue (AGRICOLA)

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  9. Article: The history of lupus erythematosus.

    Mallavarapu, Ravi K / Grimsley, Edwin W

    Southern medical journal

    2007  Volume 100, Issue 9, Page(s) 896–898

    Abstract: This article explores the history of lupus erythematosus from the origins of the name to the most modern therapeutic advances. The review includes information about the origin of the name "lupus," the first clear description of the skin lesions, the ... ...

    Abstract This article explores the history of lupus erythematosus from the origins of the name to the most modern therapeutic advances. The review includes information about the origin of the name "lupus," the first clear description of the skin lesions, the discovery of the systemic and discoid forms, and further advances which define our current view of this illness. The classical descriptions of Hippocrates, Paracelsus, Manardi, Rudolph Virchow, Cazenave, Robert Willan, and Moritz Kaposi are chronologically described. Later, the contributions of Sir William Osler, Jonathan Hutchinson, Sequira and Balean, Kraus and Bohac, Libman and Sacks, Malcolm Hargraves, and Edmund L. Dubois are highlighted. The major breakthroughs of the modern period, including the diagnostic tests, animal models, and genetics, are briefly described. The article ends with the history of drug-induced lupus, diagnostic criteria, and the history of the therapy of lupus erythematosus. With modern therapeutic advances, the mortality rate from lupus erythematosus has decreased substantially. It is hoped that current research will further improve the prognosis of this disease in the near future.
    MeSH term(s) History, 16th Century ; History, 18th Century ; History, 19th Century ; History, 20th Century ; History, Ancient ; History, Medieval ; Humans ; Lupus Erythematosus, Cutaneous/history ; Lupus Erythematosus, Systemic/diagnosis ; Lupus Erythematosus, Systemic/history ; Lupus Erythematosus, Systemic/therapy ; Terminology as Topic
    Language English
    Publishing date 2007-09
    Publishing country United States
    Document type Historical Article ; Journal Article
    ZDB-ID 185329-6
    ISSN 1541-8243 ; 0038-4348
    ISSN (online) 1541-8243
    ISSN 0038-4348
    DOI 10.1097/SMJ.0b013e318073c9eb
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    Zs.MO 336: Show issues

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  10. Article: Collapsing glomerulopathy presenting as the initial manifestation of systemic lupus erythematosus.

    Mallavarapu, Ravi K / Nandigam, Sitharam C / Peskoe, Stanley T

    NDT plus

    2008  Volume 1, Issue 6, Page(s) 452–453

    Language English
    Publishing date 2008-07-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 2410383-4
    ISSN 1753-0784
    ISSN 1753-0784
    DOI 10.1093/ndtplus/sfn100
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    Zs.MO 562: Show issues

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