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  1. Book ; Online: COVID-19 in Southeast Asia : Insights for a post-pandemic world

    Mckenzie, Murray / Bang Shin, Hyun / OH, DO YOUNG

    2022  

    Keywords Anthropology ; Economic geography ; Sociology ; East & Southeast Asian languages ; City & town planning - architectural aspects ; Economy ; Urbanization ; Migrants ; Mobilities ; Communities ; Southeast Asia ; COVID-19
    Size 1 electronic resource (342 pages)
    Publisher LSE Press
    Publishing place London
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021290905
    ISBN 9781909890763 ; 1909890766
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online: Preventive and Acute Intervention for Intracranial Atherosclerotic Disease

    Moon Kim, Byung / Young Bang, Oh / Chun-Ho Yu, Simon

    2020  

    Keywords Medicine ; Neurology & clinical neurophysiology ; intracranial atherosclerosis ; endovascular treatment ; large vessel occlusion ; preventive treatment ; ischemic stroke
    Size 1 electronic resource (109 pages)
    Publisher Frontiers Media SA
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021230865
    ISBN 9782889639243 ; 288963924X
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Article ; Online: Message from the editors to our reviewers

    Oh Young Bang

    Precision and Future Medicine, Vol 6, Iss 1, Pp 1-

    2022  Volume 1

    Keywords Medicine ; R
    Language English
    Publishing date 2022-03-01T00:00:00Z
    Publisher Sungkyunkwan University School of Medi
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Real-time online point-of-view filming education for teaching clinical skills to medical students.

    Bang, Gwanwook / Kwon, Oh Young

    Korean journal of medical education

    2022  Volume 34, Issue 3, Page(s) 231–237

    Abstract: Purpose: This study aimed to measure the educational satisfaction with and effectiveness of real-time online point-of-view filming (POVF) clinical skills education in medical students.: Methods: Medical students participated in a 120-minute clinical ... ...

    Abstract Purpose: This study aimed to measure the educational satisfaction with and effectiveness of real-time online point-of-view filming (POVF) clinical skills education in medical students.
    Methods: Medical students participated in a 120-minute clinical skills education session. The session consisted of emergency procedures, wound management, and vascular access. The authors provided real-time online POVF using a smartphone. A questionnaire survey was issued to the students after the class, and their satisfaction with education, educational environment, and effectiveness were analyzed.
    Results: Responses about satisfaction with POVF education were very positive in all grades. However, approximately half of the students were satisfied with the smoothness of listening to a lecture and the video quality. More than half of the students responded positively to the question about educational effectiveness.
    Conclusion: In these times of non-classroom teaching brought on by the coronavirus disease 2019 (COVID-19) pandemic, POVF clinical skills education is likely to be a very useful educational tool. If disadvantages such as insufficient feedback or environmental problems can be addressed, it could serve as an alternative method of clinical skills education even after the COVID-19 pandemic.
    MeSH term(s) COVID-19 ; Clinical Competence ; Education, Distance ; Humans ; Pandemics ; Students, Medical
    Language English
    Publishing date 2022-08-26
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2846769-3
    ISSN 2005-7288 ; 2005-2367 ; 2005-727X ; 1225-8067
    ISSN (online) 2005-7288 ; 2005-2367
    ISSN 2005-727X ; 1225-8067
    DOI 10.3946/kjme.2022.233
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Collateral Status and Outcomes after Thrombectomy.

    Lee, Jin Soo / Bang, Oh Young

    Translational stroke research

    2022  Volume 14, Issue 1, Page(s) 22–37

    Abstract: Endovascular treatment (EVT) using novel mechanical thrombectomy devices has been the gold standard for patients with acute ischemic stroke caused by large vessel occlusion. Selection criteria of randomized control trials commonly include baseline ... ...

    Abstract Endovascular treatment (EVT) using novel mechanical thrombectomy devices has been the gold standard for patients with acute ischemic stroke caused by large vessel occlusion. Selection criteria of randomized control trials commonly include baseline infarct volume with or without penumbra evaluation. Although the collateral status has been studied and is known to modify imaging results and clinical course, it has not been commonly used for trials. Many post hoc studies, however, revealed that collateral status can help predict infarct growth, recanalization success, decreased hemorrhagic transformation after EVT, and extension of the therapeutic time window for revascularization. Here, we systematically review the recent literature and summarized the outcomes of EVT according to the collateral status of patients with acute ischemic stroke caused by large vessel occlusion. The studies reviewed indicate that pretreatment collateral circulation is associated with both clinical and imaging outcomes after EVT in patients with acute ischemic stroke due to large vessel occlusion although most patients were already selected by other imaging or clinical criteria. However, treatment decisions using information on patients' collateral status have not progressed in clinical practice. Further randomized trials are needed to evaluate the risks and benefits of EVT in consideration of collateral status.
    MeSH term(s) Humans ; Brain Ischemia/diagnostic imaging ; Brain Ischemia/surgery ; Stroke/diagnostic imaging ; Stroke/surgery ; Ischemic Stroke/complications ; Endovascular Procedures/methods ; Thrombectomy/methods ; Infarction/complications ; Treatment Outcome
    Language English
    Publishing date 2022-06-10
    Publishing country United States
    Document type Systematic Review ; Journal Article ; Review
    ZDB-ID 2541897-X
    ISSN 1868-601X ; 1868-4483
    ISSN (online) 1868-601X
    ISSN 1868-4483
    DOI 10.1007/s12975-022-01046-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Erratum to: Stem cell-derived extracellular vesicle therapy for acute brain insults and neurodegenerative diseases.

    Bang, Oh Young / Kim, Ji-Eun

    BMB reports

    2022  Volume 55, Issue 4, Page(s) 204

    Abstract: ... mesenchymal stem cell (MSC) injection. Modified from Bang et al. (10) 3. Adding a Reference 10. Bang OY, Kim EH, Cho YH ...

    Abstract [Erratum to: BMB Reports 2022; 55(1): 20-29, PMID: 35000673] This article was republished on 30 April 2022, to correct the online version of the article which displayed an incorrect References. After online publication of this article, the authors noticed an error in the missing reference section for the page 21 and the Figure 1. The correct statement of this article should have read as below. 1. Our pre-specified biomarker sub-study showed that circulating EVs were markedly increased immediately after intravenous injection of MSCs (10). In this study, the number of the circulating EVs varied among patients after the application of the same dose of MSCs, and was associated with motor function improvement, as assessed by clinical assessment and multimodal magnetic resonance imaging (MRI) as shown in Fig. 1 (10). 2. Fig. 1. Association between elevated levels of circular extracellular vesicles (EVs) and stroke outcome after mesenchymal stem cell (MSC) injection. Modified from Bang et al. (10) 3. Adding a Reference 10. Bang OY, Kim EH, Cho YH et al (2022) Circulating extracellular vesicles in stroke patients treated with mesenchymal stem cells: a biomarker analysis of a randomized trial. Stroke [Epub Ahead of Print], https://doi.org/10.1161/STROKEAHA.121.036545 The authors apologize for any inconvenience caused. The References of Original PDF version have been corrected.
    Language English
    Publishing date 2022-05-04
    Publishing country Korea (South)
    Document type Published Erratum
    ZDB-ID 2410389-5
    ISSN 1976-670X ; 1976-6696
    ISSN (online) 1976-670X
    ISSN 1976-6696
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Stem cell-derived extracellular vesicle therapy for acute brain insults and neurodegenerative diseases.

    Bang, Oh Young / Kim, Ji-Eun

    BMB reports

    2022  Volume 55, Issue 1, Page(s) 20–29

    Abstract: Stem cell-based therapy is a promising approach for treating a variety of disorders, including acute brain insults and neurodegenerative diseases. Stem cells such as mesenchymal stem cells (MSCs) secrete extracellular vesicles (EVs), circular membrane ... ...

    Abstract Stem cell-based therapy is a promising approach for treating a variety of disorders, including acute brain insults and neurodegenerative diseases. Stem cells such as mesenchymal stem cells (MSCs) secrete extracellular vesicles (EVs), circular membrane fragments (30 nm-1 μm) that are shed from the cell surface, carrying several therapeutic molecules such as proteins and microRNAs. Because EV-based therapy is superior to cell therapy in terms of scalable production, biodistribution, and safety profiles, it can be used to treat brain diseases as an alternative to stem cell therapy. This review presents evidences evaluating the role of stem cell-derived EVs in stroke, traumatic brain injury, and degenerative brain diseases, such as Alzheimer's disease and Parkinson' disease. In addition, stem cell-derived EVs have better profiles in biocompatibility, immunogenicity, and safety than those of small chemical and macromolecules. The advantages and disadvantages of EVs compared with other strategies are discussed. Even though EVs obtained from native stem cells have potential in the treatment of brain diseases, the successful clinical application is limited by the short half-life, limited targeting, rapid clearance after application, and insufficient payload. We discuss the strategies to enhance the efficacy of EV therapeutics. Finally, EV therapies have yet to be approved by the regulatory authorities. Major issues are discussed together with relevant advances in the clinical application of EV therapeutics. [BMB Reports 2022; 55(1): 20-29].
    MeSH term(s) Brain/metabolism ; Extracellular Vesicles/metabolism ; Humans ; Mesenchymal Stem Cells ; Neurodegenerative Diseases/metabolism ; Neurodegenerative Diseases/therapy ; Tissue Distribution
    Language English
    Publishing date 2022-01-08
    Publishing country Korea (South)
    Document type News ; Review
    ZDB-ID 2410389-5
    ISSN 1976-670X ; 1976-6696
    ISSN (online) 1976-670X
    ISSN 1976-6696
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Lyoprotectant Constituents Suited for Lyophilization and Reconstitution of Stem-Cell-Derived Extracellular Vesicles.

    Kang, Wu Young / Shin, Eun Kyoung / Kim, Eun Hee / Kang, Min-Ho / Bang, Chi Young / Bang, Oh Young / Cha, Jae Min

    Biomaterials research

    2024  Volume 28, Page(s) 5

    Abstract: Stem-cell-derived extracellular vesicles (EVs) are emerging as an alternative approach to stem cell therapy. Successful lyophilization of EVs could enable convenient storage and distribution of EV medicinal products at room temperature for long periods, ... ...

    Abstract Stem-cell-derived extracellular vesicles (EVs) are emerging as an alternative approach to stem cell therapy. Successful lyophilization of EVs could enable convenient storage and distribution of EV medicinal products at room temperature for long periods, thus considerably increasing the accessibility of EV therapeutics to patients. In this study, we aimed to identify an appropriate lyoprotectant composition for the lyophilization and reconstitution of stem-cell-derived EVs. MSC-derived EVs were lyophilized using different lyoprotectants, such as dimethyl sulfoxide, mannitol, trehalose, and sucrose, at varying concentrations. Our results revealed that a mixture of trehalose and sucrose at high concentrations could support the formation of amorphous ice by enriching the amorphous phase of the solution, which successfully inhibited the acceleration of buffer component crystallization during lyophilization. Lyophilized and reconstituted EVs were thoroughly evaluated for concentration and size, morphology, and protein and RNA content. The therapeutic effects of the reconstituted EVs were examined using a tube formation assay with human umbilical vein endothelial cells. After rehydration of the lyophilized EVs, most of their generic characteristics were well-maintained, and their therapeutic capacity recovered to levels similar to those of freshly collected EVs. The concentrations and morphologies of the lyophilized EVs were similar to the initial features of the fresh EV group until day 30 at room temperature, although their therapeutic capacity appeared to decrease after 7 days. Our study suggests an appropriate composition of lyoprotectants, particularly for EV lyophilization, which could encourage the applications of stem-cell-derived EV therapeutics in the health industry.
    Language English
    Publishing date 2024-02-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 2775188-0
    ISSN 2055-7124 ; 1226-4601
    ISSN (online) 2055-7124
    ISSN 1226-4601
    DOI 10.34133/bmr.0005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Coronavirus disease in 2020 and Precision and Future Medicine

    Oh Young Bang

    Precision and Future Medicine, Vol 4, Iss 3, Pp 81-

    2020  Volume 82

    Keywords Medicine ; R
    Language English
    Publishing date 2020-09-01T00:00:00Z
    Publisher Sungkyunkwan University School of Medi
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Message from the P&FM Editors to our ad hoc Reviewers

    Oh Young Bang

    Precision and Future Medicine, Vol 4, Iss 1, Pp 1-

    2020  Volume 1

    Keywords Medicine ; R
    Language English
    Publishing date 2020-03-01T00:00:00Z
    Publisher Sungkyunkwan University School of Medi
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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