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  1. Article ; Online: Applying radiobiology to clinical molecular radiotherapy.

    Murray, Iain / Flux, Glenn

    Nuclear medicine and biology

    2021  Volume 100-101, Page(s) 1–3

    MeSH term(s) Radiobiology
    Language English
    Publishing date 2021-05-25
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 1138098-6
    ISSN 1872-9614 ; 0883-2897 ; 0969-8051
    ISSN (online) 1872-9614
    ISSN 0883-2897 ; 0969-8051
    DOI 10.1016/j.nucmedbio.2021.05.005
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1090: Show issues Location:
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  2. Article ; Online: Joint preservation techniques

    Iain R. Murray / Rachel Frank / Seth L. Sherman

    Journal of Cartilage & Joint Preservation, Vol 3, Iss 1, Pp 100116- (2023)

    where are we in 2023?

    2023  

    Keywords Diseases of the musculoskeletal system ; RC925-935 ; Other systems of medicine ; RZ201-999 ; Sports medicine ; RC1200-1245
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Human Gait Modeling, Prediction and Classification for Level Walking Using Harmonic Models Derived from a Single Thigh-Mounted IMU.

    Abhayasinghe, Nimsiri / Murray, Iain

    Sensors (Basel, Switzerland)

    2022  Volume 22, Issue 6

    Abstract: The majority of human gait modeling is based on hip, foot or thigh acceleration. The regeneration accuracy of these modeling approaches is not very high. This paper presents a harmonic approach to modeling human gait during level walking based on ... ...

    Abstract The majority of human gait modeling is based on hip, foot or thigh acceleration. The regeneration accuracy of these modeling approaches is not very high. This paper presents a harmonic approach to modeling human gait during level walking based on gyroscopic signals for a single thigh-mounted Inertial Measurement Unit (IMU) and the flexion-extension derived from a single thigh-mounted IMU. The thigh angle can be modeled with five significant harmonics, with a regeneration accuracy of over 0.999 correlation and less than 0.5° RMSE per stride cycle. Comparable regeneration accuracies can be achieved with nine significant harmonics for the gyro signal. The fundamental frequency of the harmonic model can be estimated using the stride time, with an error level of 0.0479% (±0.0029%). Six commonly observed stride patterns, and harmonic models of thigh angle and gyro signal for those stride patterns, are presented in this paper. These harmonic models can be used to predict or classify the strides of walking trials, and the results are presented herein. Harmonic models may also be used for activity recognition. It has shown that human gait in level walking can be modeled with a harmonic model of thigh angle or gyro signal, using a single thigh-mounted IMU, to higher accuracies than existing techniques.
    MeSH term(s) Acceleration ; Foot ; Gait ; Humans ; Thigh ; Walking
    Language English
    Publishing date 2022-03-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s22062164
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  4. Article ; Online: Consensus statements: when and how?

    Murray, Iain R / Makaram, Navnit S / LaPrade, Robert F / Haddad, Fares S

    The bone & joint journal

    2023  Volume 105-B, Issue 4, Page(s) 343–346

    Abstract: The Bone & Joint ... ...

    Abstract The Bone & Joint Journal
    MeSH term(s) Consensus ; Periodicals as Topic
    Language English
    Publishing date 2023-03-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 2697156-2
    ISSN 2049-4408 ; 2049-4394
    ISSN (online) 2049-4408
    ISSN 2049-4394
    DOI 10.1302/0301-620X.105B4.BJJ-2023-0048
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6989: Show issues Location:
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  5. Article ; Online: Design and Evaluation of an Alternative Control for a Quad-Rotor Drone Using Hand-Gesture Recognition.

    Khaksar, Siavash / Checker, Luke / Borazjan, Bita / Murray, Iain

    Sensors (Basel, Switzerland)

    2023  Volume 23, Issue 12

    Abstract: Gesture recognition is a mechanism by which a system recognizes an expressive and purposeful action made by a user's body. Hand-gesture recognition (HGR) is a staple piece of gesture-recognition literature and has been keenly researched over the past 40 ... ...

    Abstract Gesture recognition is a mechanism by which a system recognizes an expressive and purposeful action made by a user's body. Hand-gesture recognition (HGR) is a staple piece of gesture-recognition literature and has been keenly researched over the past 40 years. Over this time, HGR solutions have varied in medium, method, and application. Modern developments in the areas of machine perception have seen the rise of single-camera, skeletal model, hand-gesture identification algorithms, such as media pipe hands (MPH). This paper evaluates the applicability of these modern HGR algorithms within the context of alternative control. Specifically, this is achieved through the development of an HGR-based alternative-control system capable of controlling of a quad-rotor drone. The technical importance of this paper stems from the results produced during the novel and clinically sound evaluation of MPH, alongside the investigatory framework used to develop the final HGR algorithm. The evaluation of MPH highlighted the Z-axis instability of its modelling system which reduced the landmark accuracy of its output from 86.7% to 41.5%. The selection of an appropriate classifier complimented the computationally lightweight nature of MPH whilst compensating for its instability, achieving a classification accuracy of 96.25% for eight single-hand static gestures. The success of the developed HGR algorithm ensured that the proposed alternative-control system could facilitate intuitive, computationally inexpensive, and repeatable drone control without requiring specialised equipment.
    MeSH term(s) Gestures ; Unmanned Aerial Devices ; Hand ; Algorithms
    Language English
    Publishing date 2023-06-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s23125462
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  6. Article ; Online: Colonoscopy as best screening test not proven.

    Murray, Iain

    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne

    2016  Volume 188, Issue 13, Page(s) 973

    MeSH term(s) Colonoscopy ; Colorectal Neoplasms/diagnosis ; Humans ; Mass Screening ; Occult Blood
    Language English
    Publishing date 2016--20
    Publishing country Canada
    Document type Letter ; Comment
    ZDB-ID 215506-0
    ISSN 1488-2329 ; 0008-4409 ; 0820-3946
    ISSN (online) 1488-2329
    ISSN 0008-4409 ; 0820-3946
    DOI 10.1503/cmaj.1150117
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    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.136: Show issues Location:
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  7. Article ; Online: Radiation protection aspects for alpha therapies.

    Craig, Allison J / Taprogge, Jan / Flux, Glenn D / Murray, Iain

    The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of...

    2023  Volume 67, Issue 1, Page(s) 4–13

    Abstract: The use of alpha emitting radiotherapeutics is increasing, with further growth expected due to a number of clinical trials currently running involving new alpha emitters. However, literature concerning radiation safety aspects of alpha emitting ... ...

    Abstract The use of alpha emitting radiotherapeutics is increasing, with further growth expected due to a number of clinical trials currently running involving new alpha emitters. However, literature concerning radiation safety aspects of alpha emitting radionuclides is limited and most of the available literature concerns
    MeSH term(s) Humans ; Radiation Protection ; Radioisotopes/adverse effects ; Risk Assessment ; Alpha Particles/adverse effects ; Radiation Dosage
    Chemical Substances Radioisotopes
    Language English
    Publishing date 2023-01-12
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 1281687-5
    ISSN 1827-1936 ; 0392-0208 ; 1125-0135 ; 1824-4661 ; 1824-4785
    ISSN (online) 1827-1936
    ISSN 0392-0208 ; 1125-0135 ; 1824-4661 ; 1824-4785
    DOI 10.23736/S1824-4785.22.03501-4
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    Zs.A 18: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  8. Article ; Online: Immune cell-intrinsic Ah receptor facilitates the expression of antimicrobial REG3G in the small intestine.

    Chakraborty, Debopriya / Coslo, Denise M / Murray, Iain A / Vijay, Anitha / Patterson, Andrew D / Perdew, Gary H

    FASEB journal : official publication of the Federation of American Societies for Experimental Biology

    2024  Volume 38, Issue 4, Page(s) e23471

    Abstract: The intestinal epithelial layer is susceptible to damage by chemical, physiological and mechanical stress. While it is essential to maintain the integrity of epithelium, the biochemical pathways that contribute to the barrier function have not been ... ...

    Abstract The intestinal epithelial layer is susceptible to damage by chemical, physiological and mechanical stress. While it is essential to maintain the integrity of epithelium, the biochemical pathways that contribute to the barrier function have not been completely investigated. Here we demonstrate an aryl hydrocarbon receptor (AHR)-dependent mechanism facilitating the production of the antimicrobial peptide AMP regenerating islet-derived protein 3 gamma (REG3G), which is essential for intestinal homeostasis. Genetic ablation of AHR in mice impairs pSTAT3-mediated REG3G expression and increases bacterial numbers of Segmented filamentous bacteria (SFB) and Akkermansia muciniphila in the small intestine. Studies with tissue-specific conditional knockout mice revealed that the presence of AHR in the epithelial cells of the small intestine is not required for the production of REG3G through the phosphorylated STAT3-mediated pathway. However, immune-cell-specific AHR activity is necessary for normal expression of REG3G in all regions of the small intestine. A diet rich in broccoli, capable of inducing AHR activity, increases REG3G production when compared to a semi-purified diet that is devoid of ligands that can potentially activate the AHR, thus highlighting the importance of AHR in antimicrobial function. Overall, these data suggest that homeostatic antimicrobial REG3G production is increased by an AHR pathway intrinsic to the immune cells in the small intestine.
    MeSH term(s) Animals ; Mice ; Anti-Infective Agents ; Cytoskeleton ; Epithelial Cells ; Intestine, Small ; Mice, Knockout ; Receptors, Aryl Hydrocarbon/genetics
    Chemical Substances Anti-Infective Agents ; Receptors, Aryl Hydrocarbon ; Reg3g protein, mouse ; Ahr protein, mouse
    Language English
    Publishing date 2024-02-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639186-2
    ISSN 1530-6860 ; 0892-6638
    ISSN (online) 1530-6860
    ISSN 0892-6638
    DOI 10.1096/fj.202302319R
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    Zs.A 2266: Show issues Location:
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    Zs.MO 296: Show issues

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  9. Article ; Online: Native knee kinematics are reproduced during the golf swing after total knee arthroplasty apart from rotation: A case control study of hip and knee kinematics of patients returning to golf compared to match controls.

    Rankin, Conor S / Coleman, Simon / Murray, Iain R / Robinson, Patrick G / Clement, Nick D

    Journal of ISAKOS : joint disorders & orthopaedic sports medicine

    2024  

    Abstract: Objectives: Golf is a popular sport in older adults and this same population has an increasing prevalence of osteoarthritis affecting major joints such as the knee. To the authors' knowledge, the effect of Total Knee Arthroplasty (TKA) on the movements ... ...

    Abstract Objectives: Golf is a popular sport in older adults and this same population has an increasing prevalence of osteoarthritis affecting major joints such as the knee. To the authors' knowledge, the effect of Total Knee Arthroplasty (TKA) on the movements in the golf swing has not been extensively investigated despite the large prevalence of golfers who have undergone TKA. We aimed to determine lower limb joint kinematics during the golf swing and whether these are influenced following TKA.
    Methods: A case- control study was undertaken with ten right-handed golfers who had undergone TKA (cruciate-retaining single radius implant) and five matched golfers with native knees. Each golfer performed five swings with a driver whilst being recorded at 200 ​Hz by a ten-camera motion capture system. Knee and hip three-dimensional joint angles (JA) and joint angular velocities (JAV) were calculated and statistically compared between the groups at six swing events.
    Results: The left knee demonstrated large effect sizes for lower external rotation during take away, mid (p ​= ​0.01) and top of backswing in the TKA group. In contrast, the right knee demonstrated large effect sizes for lower external rotation in the TKA group during the downswing, contact and follow-through phases. There were no differences in knee flexion/extension, ab/adduction, or JAV between the groups. Both hips demonstrated statistically significantly (p ​= ​0.02 for left and p ​= ​0.04 for right) lower flexion in the TKA group during the takeaway swing event, and lower internal rotation in the backswing and greater external rotation in the downswing of the right hip.
    Conclusion: Normal knee kinematics were observed during the golf swing following TKA, with the exception of reduced external rotation in the left knee during the backswing and the right during the down swing. The differences demonstrated in the hip motion indicate that they may make compensatory movements to adjust to the reduced external rotation demonstrated in the knee.
    Level of evidence: IV.
    Language English
    Publishing date 2024-03-12
    Publishing country England
    Document type Journal Article
    ISSN 2059-7762
    ISSN (online) 2059-7762
    DOI 10.1016/j.jisako.2024.03.004
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  10. Article: Molecular networking identifies an AHR-modulating benzothiazole from white button mushrooms (

    Chen, Xiaoling / Patterson, Andrew D / Perdew, Gary H / Murray, Iain A / Kellogg, Joshua J

    Journal of functional foods

    2023  Volume 106

    Abstract: Diet-derived aryl hydrocarbon receptor (AHR) ligands have potential to maintain gut health. However, among the myriad bioactive compounds from foods, identifying novel functional ligands which would significantly impact gastrointestinal health is a ... ...

    Abstract Diet-derived aryl hydrocarbon receptor (AHR) ligands have potential to maintain gut health. However, among the myriad bioactive compounds from foods, identifying novel functional ligands which would significantly impact gastrointestinal health is a challenge. In this study, a novel AHR modulator is predicted, identified, and characterized in the white button mushroom (
    Language English
    Publishing date 2023-06-07
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2511964-3
    ISSN 1756-4646
    ISSN 1756-4646
    DOI 10.1016/j.jff.2023.105602
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    In stock of ZB MED Bonn / Germany

    Z 7830: Show issues

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