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Book ; Online: Stacked Tensegrity Mechanism for Medical Application

Khanzode, Dhruva / Jha, Ranjan / Duchalais, Emilie / Chablat, Damien

2022

Abstract: In this article a multi-segmented planar tensegrity mechanism was presented. This mechanism has a three-segment structure with each segment residing on top of another. The size of the segments may decrease proportionally from base to top, resulting in a ... ...

Abstract	In this article a multi-segmented planar tensegrity mechanism was presented. This mechanism has a three-segment structure with each segment residing on top of another. The size of the segments may decrease proportionally from base to top, resulting in a tapered shape from base to tip like an elephant trunk. The system was mechanically formulated as having linear springs and cables functioning as actuators. The singularities, as well as the stability of the parallel mechanism, were analyzed by using the principle of minimum energy. Optimization was also done to obtain the greatest angular deflection for a segment according to a ratio between the size of the base and the moving platform of the robotic system. The result of this work is a family of mechanisms that can generate the same workspace for different stability properties.
Keywords	Computer Science - Robotics
Publishing date	2022-04-04
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Short-Term Outcomes with Robotic Right Colectomy.

Kelley, Scott R / Duchalais, Emilie / Larson, David W

The American surgeon

2019 Volume 84, Issue 11, Page(s) 1768–1773

Abstract: Few series have reported on the impact of robotic right colectomy compared with conventional laparoscopy. Even fewer have reported on the outcomes of intracorporeal anastomoses. The aim of our study was to determine the impact of robotic surgery on short- ...

Abstract	Few series have reported on the impact of robotic right colectomy compared with conventional laparoscopy. Even fewer have reported on the outcomes of intracorporeal anastomoses. The aim of our study was to determine the impact of robotic surgery on short-term operative outcomes in patients undergoing right colectomy with intracorporeal anastomosis. One hundred and fourteen consecutive patients who underwent a right colectomy by two colorectal surgeons between 2012 and 2017 were included. Patients were separated into two groups: laparoscopic technique with extracorporeal anastomosis (n = 87) and robotic technique with intracorporeal anastomosis (n = 27). Univariate analysis was performed to determine differences in outcomes. Differences between cohorts were only identified with regard to gender (62
MeSH term(s)	Aged ; Analysis of Variance ; Anastomosis, Surgical/methods ; Cohort Studies ; Colectomy/adverse effects ; Colectomy/methods ; Colonic Neoplasms/mortality ; Colonic Neoplasms/pathology ; Colonic Neoplasms/surgery ; Female ; Humans ; Laparoscopy/adverse effects ; Laparoscopy/methods ; Length of Stay ; Male ; Middle Aged ; Operative Time ; Pain, Postoperative/epidemiology ; Pain, Postoperative/physiopathology ; Patient Safety ; Postoperative Complications/epidemiology ; Postoperative Complications/physiopathology ; Prognosis ; Retrospective Studies ; Risk Assessment ; Robotic Surgical Procedures/adverse effects ; Robotic Surgical Procedures/methods ; Statistics, Nonparametric ; Survival Rate ; Treatment Outcome
Language	English
Publishing date	2019-02-12
Publishing country	United States
Document type	Comparative Study ; Journal Article
ZDB-ID	202465-2
ISSN	1555-9823 ; 0003-1348
ISSN (online)	1555-9823
ISSN	0003-1348
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Article ; Online: Obstructed defaecation associated with lateral perineal postoperative hernia: Robotic mesh positioning for pelvic floor reinforcement - A video vignette.

de la Codre, Frédéric / Korkmaz, Carine / Duchalais, Emilie / Regenet, Nicolas / Meurette, Guillaume

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

2021 Volume 24, Issue 1, Page(s) 143–144

MeSH term(s)	Defecation ; Hernia/etiology ; Herniorrhaphy ; Humans ; Incisional Hernia/surgery ; Pelvic Floor/surgery ; Perineum/surgery ; Robotic Surgical Procedures ; Surgical Mesh/adverse effects
Language	English
Publishing date	2021-10-10
Publishing country	England
Document type	Letter ; Video-Audio Media
ZDB-ID	1440017-0
ISSN	1463-1318 ; 1462-8910
ISSN (online)	1463-1318
ISSN	1462-8910
DOI	10.1111/codi.15931
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Article: Defining the Immune Checkpoint Landscape in Human Colorectal Cancer Highlights the Relevance of the TIGIT/CD155 Axis for Optimizing Immunotherapy.

Ducoin, Kathleen / Bilonda-Mutala, Linda / Deleine, Cécile / Oger, Romain / Duchalais, Emilie / Jouand, Nicolas / Bossard, Céline / Jarry, Anne / Gervois-Segain, Nadine

Cancers

2022 Volume 14, Issue 17

Abstract: While immune checkpoint (IC) therapies, particularly those targeting the PD-1/PD-L1 axis, have revolutionized the treatment of melanoma and several other cancers, their effect remains very limited in colorectal cancer (CRC). To define a comprehensive ... ...

Abstract	While immune checkpoint (IC) therapies, particularly those targeting the PD-1/PD-L1 axis, have revolutionized the treatment of melanoma and several other cancers, their effect remains very limited in colorectal cancer (CRC). To define a comprehensive landscape of ICs in the human CRC tumor microenvironment (TME), we evaluated, using multiparametric flow cytometry, their ex vivo expression via tumor-infiltrating lymphocytes (TILs) (n = 40 CRCs) as well as that of their respective ligands on tumor and myeloid cells (n = 29). Supervised flow cytometry analyses showed that (i) most CD3
Language	English
Publishing date	2022-08-31
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2527080-1
ISSN	2072-6694
ISSN	2072-6694
DOI	10.3390/cancers14174261
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Article ; Online: Author's reply: Outcomes of first-line endoscopic management for patients with sigmoid volvulus.

Quénéhervé, Lucille / Duchalais, Emilie / Le Rhun, Marianne / Coron, Emmanuel

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

2019 Volume 51, Issue 7, Page(s) 1066

MeSH term(s)	Colon, Sigmoid ; Endoscopy ; Humans ; Intestinal Volvulus ; Sigmoid Diseases
Language	English
Publishing date	2019-06-03
Publishing country	Netherlands
Document type	Letter ; Comment
ZDB-ID	1459373-7
ISSN	1878-3562 ; 1125-8055
ISSN (online)	1878-3562
ISSN	1125-8055
DOI	10.1016/j.dld.2019.05.021
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Article ; Online: Management of adult intestinal stomas: The 2023 French guidelines.

Aubert, Mathilde / Buscail, Etienne / Duchalais, Emilie / Cazelles, Antoine / Collard, Maxime / Charleux-Muller, Diane / Jeune, Florence / Nuzzo, Alexandre / Pellegrin, Alexandra / Theuil, Luca / Toutain, Amandine / Trilling, Bertrand / Siproudhis, Laurent / Meurette, Guillaume / Lefevre, Jérémie H / Maggiori, Léon / Mege, Diane

Journal of visceral surgery

2024 Volume 161, Issue 2, Page(s) 106–128

Abstract: Aim: Digestive stoma are frequently performed. The last French guidelines have been published twenty years ago. Our aim was to update French clinical practice guidelines for the perioperative management of digestive stoma and stoma-related complications. ...

Abstract	Aim: Digestive stoma are frequently performed. The last French guidelines have been published twenty years ago. Our aim was to update French clinical practice guidelines for the perioperative management of digestive stoma and stoma-related complications. Methods: A systematic literature review of French and English articles published between January 2000 and May 2022 was performed. Only digestive stoma for fecal evacuation in adults were considered. Stoma in children, urinary stoma, digestive stoma for enteral nutrition, and rare stoma (Koch, perineal) were not included. Results: Guidelines include the surgical landmarks to create digestive stoma (ideal location, mucocutaneous anastomosis, utility of support rods, use of prophylactic mesh), the perioperative clinical practice guidelines (patient education, preoperative ostomy site marking, postoperative equipment, prescriptions, and follow-up), the management of early stoma-related complications (difficulties for nursing, high output, stoma necrosis, retraction, abscess and peristomal skin complications), and the management of late stoma-related complications (stoma prolapse, parastomal hernia, stoma stenosis, late stoma retraction). A level of evidence was assigned to each statement. Conclusion: These guidelines will be very useful in clinical practice, and allow to delete some outdated dogma.
MeSH term(s)	Humans ; France ; Surgical Stomas/adverse effects ; Adult ; Postoperative Complications/prevention & control ; Practice Guidelines as Topic ; Colostomy
Language	English
Publishing date	2024-03-05
Publishing country	France
Document type	Journal Article ; Systematic Review ; Practice Guideline
ISSN	1878-7886
ISSN (online)	1878-7886
DOI	10.1016/j.jviscsurg.2024.02.002
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Article ; Online: Multi-professional development of a competency framework for patients with a Port-a-Cath (PAC).

Nizet, Pierre / Grivel, Charlotte / Feldman, David / Brochet, Elodie / Le Gouill, Christèle / Lindenberg, Fabien / Corbineau, Erwan / Cormier, Nicolas / Clouet, Johann / Duchalais, Emilie / Huon, Jean-François

Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners

2023 Volume 30, Issue 1, Page(s) 100–104

Abstract: Purpose: In France, 40,000 Port-a-Cath (PAC) are inserted each year. These medical devices are prone to complications during their insertion or use. The education of patients wearing these devices could be a lever to reduce the risk of complications. ... ...

Abstract	Purpose: In France, 40,000 Port-a-Cath (PAC) are inserted each year. These medical devices are prone to complications during their insertion or use. The education of patients wearing these devices could be a lever to reduce the risk of complications. The objective of this work was to develop, in a multi-professional and consensual manner, a unique and specific skills reference framework for patients with PAC and to propose it as a reference tool for health professionals. Methods: A multidisciplinary working group was set up to draw up this reference framework of skills. The first stage of the work consisted of a reflection leading to an exhaustive list of competencies necessary for the patient. These skills were then classified according to three different fields of knowledge (theoretical, know-how and attitudes). Finally, the working group identified priority competencies and established a grid that can be used to evaluate the level of acquisition of these competencies. Results: Fifteen competencies were identified: five relating to theoretical knowledge, six relating to know-how and four relating to attitudes. These competencies were broken down into sub-competences. Seven competencies or sub-competencies were selected to constitute the list of priority competencies. Discussion: This competency framework provides a reference framework for the education of patients with PAC and will help to harmonise practices within the different teams that care for patients with PAC.
MeSH term(s)	Humans ; Health Personnel/education ; Clinical Competence
Language	English
Publishing date	2023-04-06
Publishing country	England
Document type	Journal Article
ZDB-ID	1330764-2
ISSN	1477-092X ; 1078-1552
ISSN (online)	1477-092X
ISSN	1078-1552
DOI	10.1177/10781552231168573
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Zs.A 4488: Show issues

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Article ; Online: Nationwide Analysis of Urinary Retention Following Inguinal Hernia Repair: Results from the National Prospective Hernia Registry.

Drissi, Farouk / Gillion, Jean-François / Roquilly, Antoine / Luyckx, François / Duchalais, Emilie

World journal of surgery

2020 Volume 44, Issue 8, Page(s) 2638–2646

Abstract: Background: Urinary retention is one of the most common early postoperative complications following inguinal hernia repair (IHR). The aim of this study was to assess the incidence of postoperative urinary retention (POUR) and to identify associated risk ...

Abstract	Background: Urinary retention is one of the most common early postoperative complications following inguinal hernia repair (IHR). The aim of this study was to assess the incidence of postoperative urinary retention (POUR) and to identify associated risk factors. Method: Data of consecutive patients undergoing IHR from 2011 to 2017 were collected from a national multicenter cohort. POUR was defined as the inability to void requiring urinary catheterization. A multivariate analysis was conducted to identify independent risk factors for POUR. Results: Of 13,736 patients, 109 (0.8%) developed POUR. Patients with POUR had longer hospital length of stay (p < 0.001). IHR was performed by a laparoscopic or an open approach in 7012 (51.3%) and 6655 (48.7%) patients, respectively, and spinal anesthesia was realized in 591 (4.3%) patients. Ambulatory surgery was performed in 10,466 (76.6%) patients. Multivariate analysis identified preoperative dysuria (0R 3.73, p < 0.001), diabetes mellitus (OR 1.98, p = 0.029) and spinal anesthesia (OR 7.56, p < 0.001) as independent preoperative risk factors associated with POUR. POUR was the cause of ambulatory failure in 35 (10.2%) patients who required unanticipated admission. Conclusion: The incidence of POUR following IHR remains low but impacts hospitalization settings. Preoperative risk factors for POUR should be considered for the choice of the anesthetic technique.
MeSH term(s)	Aged ; Aged, 80 and over ; Ambulatory Surgical Procedures/adverse effects ; Ambulatory Surgical Procedures/statistics & numerical data ; Anesthesia, Spinal/statistics & numerical data ; Diabetes Mellitus/epidemiology ; Dysuria/epidemiology ; Female ; France/epidemiology ; Hernia, Inguinal/surgery ; Herniorrhaphy/adverse effects ; Herniorrhaphy/statistics & numerical data ; Humans ; Incidence ; Laparoscopy/statistics & numerical data ; Length of Stay ; Male ; Middle Aged ; Patient Admission ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Preoperative Period ; Registries ; Retrospective Studies ; Risk Factors ; Urinary Retention/epidemiology ; Urinary Retention/etiology
Language	English
Publishing date	2020-05-11
Publishing country	United States
Document type	Journal Article ; Multicenter Study
ZDB-ID	224043-9
ISSN	1432-2323 ; 0364-2313
ISSN (online)	1432-2323
ISSN	0364-2313
DOI	10.1007/s00268-020-05538-7
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Article ; Online: Robotic right colectomy with intracorporeal anastomosis for malignancy.

Kelley, Scott R / Duchalais, Emilie / Larson, David W

Journal of robotic surgery

2017 Volume 12, Issue 3, Page(s) 461–466

Abstract: Techniques for robotic resection of the right colon have not been extensively published or adopted. We report our initial experience of robotic right colectomy with intracorporeal anastomosis and specimen extraction through a Pfannenstiel incision ... ...

Abstract	Techniques for robotic resection of the right colon have not been extensively published or adopted. We report our initial experience of robotic right colectomy with intracorporeal anastomosis and specimen extraction through a Pfannenstiel incision retrospectively. Twenty-one consecutive patients with a right colon cancer (n = 18) or polyp too large to remove endoscopically (n = 3) were treated at Mayo Clinic Rochester, Minnesota. Main outcomes measured were estimated blood loss, operative time, conversion rate, return of gastrointestinal function, length of stay, overall and severe complications, discharge status, and pathology. All 21 procedures were technically successful without the need for conversion. The mean total operative time was 250 ± 56 min, estimated blood loss was less than 100 mL in 19 (90%), only 1 (5%) ileus occurred, mean length of stay and return of gastrointestinal function was 4 ± 1.3 and 1 ± 0.6 days, respectively, only 1 (5%) patient experienced a Dindo grade ≥ 3 complication, and 20 (95%) were discharged to home. Mean number of nodes resected was 26 ± 12. Tumors were diagnosed as stage 0 in 3 (14%), stage I in 7 (33%), stage II in 4 (19%), stage III in 6 (28%), and stage IV in 1 (5%). Main limitations were nonrandomized nature, single institution experience, small patient sample size, and procedures only being performed by two surgeons. Finally, we conclude that robotic right colectomy with central mesocolic excision, intracorporeal anastomosis, and extraction through a Pfannenstiel incision is technically feasible, efficacious, oncologically acceptable, and safe to perform.
MeSH term(s)	Aged ; Anastomosis, Surgical/adverse effects ; Anastomosis, Surgical/methods ; Colectomy/adverse effects ; Colectomy/methods ; Colonic Neoplasms/surgery ; Female ; Humans ; Male ; Middle Aged ; Postoperative Complications ; Retrospective Studies ; Robotic Surgical Procedures/adverse effects ; Robotic Surgical Procedures/methods
Language	English
Publishing date	2017-10-25
Publishing country	England
Document type	Journal Article
ZDB-ID	2268283-1
ISSN	1863-2491 ; 1863-2483
ISSN (online)	1863-2491
ISSN	1863-2483
DOI	10.1007/s11701-017-0759-0
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Article ; Online: Long-term Oncological Outcomes Following Anastomotic Leak in Rectal Cancer Surgery.

Crippa, Jacopo / Duchalais, Emilie / Machairas, Nikolaos / Merchea, Amit / Kelley, Scott R / Larson, David W

Diseases of the colon and rectum

2020 Volume 63, Issue 6, Page(s) 769–777

Abstract: Background: Anastomotic leak remains a critical complication after restorative rectal cancer surgery and is associated with significant morbidity and mortality rates, whereas reported rates range from 4% to 29%. Whether the occurrence of leak may have ... ...

Abstract	Background: Anastomotic leak remains a critical complication after restorative rectal cancer surgery and is associated with significant morbidity and mortality rates, whereas reported rates range from 4% to 29%. Whether the occurrence of leak may have an impact on long-term oncological outcomes is under debate. Objective: This study aimed to describe the oncological impact of anastomotic leak on patients undergoing sphincter-preserving surgery for rectal adenocarcinoma. Design: This is a retrospective review of a prospectively maintained database. Settings: The study was conducted at a high-volume colorectal center. Patients: Data on patients who underwent restorative surgery for rectal adenocarcinoma from January 2000 until December 2013 were retrospectively analyzed. Main outcome measures: The primary outcome measured was the impact of anastomotic leak, defined according to the classification proposed by the International Study Group of Rectal Cancer, on long-term overall survival, disease-free survival, disease-specific survival, and local recurrence. Results: A total of 787 patients undergoing sphincter-preserving surgery for rectal cancer met the inclusion criteria. Forty-two (5.3%) patients presented a symptomatic anastomotic leak. The median follow-up period was 64 months. Fifty-one (6.5%) patients experienced a cancer-related death, 2 of 42 in the anastomotic leak group. Five-year overall survival, disease-specific survival, and disease-free survival were 88%, 94.7%, and 85.3%. Local recurrence rate was 2%. There was no difference in long-term overall survival, disease-specific survival, disease-free survival, and local recurrence rate between groups. On a multivariable analysis, anastomotic leak did not impact oncological outcomes. Limitations: This study was limited by retrospective analysis. Conclusions: The occurrence of anastomotic leak after restorative resection for rectal cancer did not impact long-term oncological outcomes in our cohort of patients. See Video Abstract at http://links.lww.com/DCR/B187. RESULTADOS ONCOLÓGICOS A LARGO PLAZO DESPUÉS DE UNA FUGA ANASTOMÓTICA EN CIRUGÍA DE CÁNCER RECTAL: La fuga anastomótica sigue siendo una complicación crítica después de la cirugía restauradora del cáncer rectal y se asocia con tasas significativas de morbilidad y mortalidad, mientras que las tasas reportadas varían del 4% al 29%. Se está debatiendo si la aparición de fugas puede tener un impacto en los resultados oncológicos a largo plazo.Describir el impacto oncológico de la fuga anastomótica en pacientes sometidos a cirugía de preservación del esfínter para adenocarcinoma rectal.Revisión retrospectiva de una base de datos mantenida prospectivamente.El estudio se realizó en un centro colorrectal de alto volumen.Se analizaron retrospectivamente los datos de pacientes que se sometieron a cirugía reparadora por adenocarcinoma rectal desde Enero de 2000 hasta Diciembre de 2013.Impacto de la fuga anastomótica, definida de acuerdo con la clasificación propuesta por el Grupo de Estudio Internacional del Cáncer Rectal (International Study Group of Rectal Cancer), sobre la supervivencia general a largo plazo, la supervivencia libre de enfermedad, la supervivencia específica de la enfermedad y la recurrencia local.Un total de 787 pacientes sometidos a cirugía para preservar el esfínter por cáncer rectal cumplieron con los criterios de inclusión. Cuarenta y dos (5.3%) pacientes presentaron una fuga anastomótica sintomática. El tiempo mediano del período de seguimiento fue de 64 meses. Cincuenta y un (6.5%) pacientes sufrieron muerte relacionada con el cáncer, 2 de 42 en el grupo de fuga anastomótica. La supervivencia global a cinco años, la supervivencia específica de la enfermedad y la supervivencia libre de enfermedad fueron del 88%, 94.7% y 85.3%, respectivamente. La tasa de recurrencia local fue del 2%. No hubo diferencias en la supervivencia global a largo plazo, la supervivencia específica de la enfermedad, la supervivencia libre de enfermedad y la tasa de recurrencia local entre los grupos. En un análisis multivariable, la fuga anastomótica no afectó los resultados oncológicos.Este estudio fue limitado por análisis retrospectivo.La aparición de fuga anastomótica después de la resección restauradora para el cáncer rectal no afectó los resultados oncológicos a largo plazo en nuestra cohorte de pacientes. Consulte Video Resumen en http://links.lww.com/DCR/B187. (Traducción-Dr. Yesenia Rojas-Kahlil).
MeSH term(s)	Adenocarcinoma/surgery ; Adult ; Aged ; Aged, 80 and over ; Anastomotic Leak/etiology ; Data Management ; Disease-Free Survival ; Female ; Follow-Up Studies ; Humans ; Ileostomy/adverse effects ; Ileostomy/methods ; Male ; Middle Aged ; Neoplasm Recurrence, Local/epidemiology ; Non-Randomized Controlled Trials as Topic/methods ; Outcome Assessment, Health Care ; Rectal Neoplasms/complications ; Rectal Neoplasms/mortality ; Rectal Neoplasms/surgery ; Retrospective Studies
Language	English
Publishing date	2020-01-07
Publishing country	United States
Document type	Journal Article ; Video-Audio Media
ZDB-ID	212581-x
ISSN	1530-0358 ; 0012-3706
ISSN (online)	1530-0358
ISSN	0012-3706
DOI	10.1097/DCR.0000000000001634
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