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  1. Article ; Online: FUS maintains TAZ fluidity and function.

    Hong, Wanjin

    Nature cell biology

    2024  Volume 26, Issue 1, Page(s) 34–36

    MeSH term(s) Transcription Factors
    Chemical Substances Transcription Factors
    Language English
    Publishing date 2024-01-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 1474722-4
    ISSN 1476-4679 ; 1465-7392
    ISSN (online) 1476-4679
    ISSN 1465-7392
    DOI 10.1038/s41556-023-01318-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5169: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 12: Show issues

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  2. Article ; Online: Hippo Signaling at the Hallmarks of Cancer and Drug Resistance.

    Kumar, Ramesh / Hong, Wanjin

    Cells

    2024  Volume 13, Issue 7

    Abstract: Originally identified ... ...

    Abstract Originally identified in
    MeSH term(s) United States ; Animals ; Humans ; Hippo Signaling Pathway ; Drosophila melanogaster/metabolism ; Trans-Activators/metabolism ; YAP-Signaling Proteins ; Neoplasms/drug therapy ; Neoplasms/pathology ; Intracellular Signaling Peptides and Proteins/metabolism ; Drug Resistance
    Chemical Substances Trans-Activators ; YAP-Signaling Proteins ; Intracellular Signaling Peptides and Proteins
    Language English
    Publishing date 2024-03-22
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2661518-6
    ISSN 2073-4409 ; 2073-4409
    ISSN (online) 2073-4409
    ISSN 2073-4409
    DOI 10.3390/cells13070564
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Combating COVID-19 with Chloroquine.

    Hong, Wanjin

    Journal of molecular cell biology

    2020  Volume 12, Issue 4, Page(s) 249–250

    MeSH term(s) Betacoronavirus/physiology ; COVID-19 ; Chloroquine/therapeutic use ; Coronavirus Infections/drug therapy ; Drug Combinations ; Endocytosis/drug effects ; Humans ; Lopinavir/therapeutic use ; Pandemics ; Pneumonia, Viral/drug therapy ; Ritonavir/therapeutic use ; SARS-CoV-2
    Chemical Substances Drug Combinations ; lopinavir-ritonavir drug combination ; Lopinavir (2494G1JF75) ; Chloroquine (886U3H6UFF) ; Ritonavir (O3J8G9O825)
    Keywords covid19
    Language English
    Publishing date 2020-06-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2500949-7
    ISSN 1759-4685 ; 1674-2788
    ISSN (online) 1759-4685
    ISSN 1674-2788
    DOI 10.1093/jmcb/mjaa015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: SNXs take center stage in endosomal sorting.

    Hong, Wanjin

    Nature cell biology

    2019  Volume 21, Issue 10, Page(s) 1175–1177

    MeSH term(s) Animals ; Endosomal Sorting Complexes Required for Transport/metabolism ; Endosomes/metabolism ; Humans ; Protein Transport ; Sorting Nexins/chemistry ; Sorting Nexins/genetics ; Sorting Nexins/metabolism
    Chemical Substances Endosomal Sorting Complexes Required for Transport ; SNX5 protein, human ; SNX6 protein, human ; Sorting Nexins
    Language English
    Publishing date 2019-10-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 1474722-4
    ISSN 1476-4679 ; 1465-7392
    ISSN (online) 1476-4679
    ISSN 1465-7392
    DOI 10.1038/s41556-019-0401-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5169: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 12: Show issues

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  6. Article ; Online: Combating COVID-19 with Chloroquine

    Hong, Wanjin

    Journal of Molecular Cell Biology

    2020  Volume 12, Issue 4, Page(s) 249–250

    Keywords Genetics ; Cell Biology ; Molecular Biology ; General Medicine ; covid19
    Language English
    Publisher Oxford University Press (OUP)
    Publishing country uk
    Document type Article ; Online
    ZDB-ID 2500949-7
    ISSN 1759-4685 ; 1674-2788
    ISSN (online) 1759-4685
    ISSN 1674-2788
    DOI 10.1093/jmcb/mjaa015
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  7. Article: Oncogenetic engagement with mechanosensing.

    Chakraborty, Sayan / Hong, Wanjin

    Nature materials

    2020  Volume 19, Issue 7, Page(s) 707–709

    MeSH term(s) Carcinogenesis ; Humans ; Mechanotransduction, Cellular ; Neoplasms/therapy ; Oncogenes
    Language English
    Publishing date 2020-06-24
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 2088679-2
    ISSN 1476-4660 ; 1476-1122
    ISSN (online) 1476-4660
    ISSN 1476-1122
    DOI 10.1038/s41563-020-0700-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Editorial: A Hippo's View: From Molecular Basis to Translational Medicine.

    Zhou, Zhaocai / Yuan, Zengqiang / Hong, Wanjin / Wang, Wenqi

    Frontiers in cell and developmental biology

    2021  Volume 9, Page(s) 729155

    Language English
    Publishing date 2021-07-23
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2737824-X
    ISSN 2296-634X
    ISSN 2296-634X
    DOI 10.3389/fcell.2021.729155
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Therapeutic targeting of TEAD transcription factors in cancer.

    Pobbati, Ajaybabu V / Kumar, Ramesh / Rubin, Brian P / Hong, Wanjin

    Trends in biochemical sciences

    2023  Volume 48, Issue 5, Page(s) 450–462

    Abstract: The Hippo signaling pathway inhibits the activity of the oncogenic YAP (Yes-associated protein)/TAZ (transcriptional co-activator with PDZ-binding motif)-TEAD (TEA/ATTS domain) transcriptional complex. In cancers, inactivating mutations in upstream Hippo ...

    Abstract The Hippo signaling pathway inhibits the activity of the oncogenic YAP (Yes-associated protein)/TAZ (transcriptional co-activator with PDZ-binding motif)-TEAD (TEA/ATTS domain) transcriptional complex. In cancers, inactivating mutations in upstream Hippo components and/or enhanced activity of YAP/TAZ and TEAD have been observed. The activity of this transcriptional complex can be effectively inhibited by targeting the TEAD family of transcription factors. The development of TEAD inhibitors has been driven by the discovery that TEAD has druggable hydrophobic pockets, and is currently at the clinical development stage. Three small molecule TEAD inhibitors are currently being tested in Phase I clinical trials. In this review, we highlight the role of TEADs in cancer, discuss various avenues through which TEAD activity can be inhibited, and outline the opportunities for the administration of TEAD inhibitors.
    MeSH term(s) Humans ; TEA Domain Transcription Factors ; Transcription Factors/metabolism ; Neoplasms/drug therapy ; Hippo Signaling Pathway
    Chemical Substances TEA Domain Transcription Factors ; Transcription Factors
    Language English
    Publishing date 2023-01-26
    Publishing country England
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 194216-5
    ISSN 1362-4326 ; 0968-0004 ; 0376-5067
    ISSN (online) 1362-4326
    ISSN 0968-0004 ; 0376-5067
    DOI 10.1016/j.tibs.2022.12.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1207: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  10. Book: Protein trafficking along the exocytotic pathway

    Hong, Wanjin

    1996  

    Author's details Wanjin Hong
    Keywords Proteins / secretion ; Exocytosis ; Biological Transport ; Protein Processing, Post-Translational ; Endoplasmic Reticulum / physiology ; Golgi Apparatus / physiology ; Lysosomes / physiology ; Cell Membrane / physiology ; Exocytose ; Carrier-Proteine
    Subject Transportproteine ; Translokatoren ; Membrantransportproteine ; Exozytose
    Language English
    Size 197 S. : graph. Darst.
    Publisher Springer u.a.
    Publishing place New York u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT007429723
    ISBN 3-540-61241-6 ; 978-3-540-61241-4
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1997 A 1115 order for loan Magazin

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