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  1. Article: Marked Atrophic Changes of the Brain in a Patient with Subacute Sclerosing Panencephalitis.

    Yasin, Faizan / Assad, Salman / Nadeem, Muhammad / Zahid, Mehr

    Cureus

    2017  Volume 9, Issue 8, Page(s) e1585

    Abstract: Subacute Sclerosing Panencephalitis (SSPE) is a debilitating disorder associated with the measles infection in childhood. It is a very rare manifestation in children. It usually presents with measles before the age of two. We report a similar case of ... ...

    Abstract Subacute Sclerosing Panencephalitis (SSPE) is a debilitating disorder associated with the measles infection in childhood. It is a very rare manifestation in children. It usually presents with measles before the age of two. We report a similar case of SSPE in a 14-year-old girl who developed this life-threatening condition in spite of receiving the measles vaccination. Despite the vaccination, the patient had suffered from measles before the age of two. This highlights the dilemma of ineffective vaccinations in developing countries. We also describe the radiologic features of SSPE in this patient, with marked atrophy seen in the occipital region following hyperintensities noticed at a relatively earlier stage.
    Language English
    Publishing date 2017-08-21
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.1585
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Management of Massively Enlarged Multiple Hydatid Cysts in the Liver of a Pediatric Patient.

    Yasin, Faizan / Ghazanfar, Haider / Assad, Salman / Bhatti, Sumbal A

    Cureus

    2017  Volume 9, Issue 9, Page(s) e1643

    Abstract: Multiple hydatid cysts in the liver are a very rare occurrence in childhood. We present a similar case in a nine-year-old girl, a resident in a rural community, who presented with two hydatid cysts in her liver. The cysts were operated upon by a ... ...

    Abstract Multiple hydatid cysts in the liver are a very rare occurrence in childhood. We present a similar case in a nine-year-old girl, a resident in a rural community, who presented with two hydatid cysts in her liver. The cysts were operated upon by a pediatric surgeon. The laboratory findings of this patient showed peripheral blood eosinophilia, elevated white blood cells, and liver enzymes. The serology was positive. The ultrasonography showed cystic masses in the liver, and the diagnosis of hydatid cysts was eventually confirmed by computed tomography (CT) of the abdomen.
    Language English
    Publishing date 2017-09-02
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.1643
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Simulation and Experimental Investigation on Carbonized Tracking Failure of EPDM/BN-based Electrical Insulation.

    Nazir, Muhammad Tariq / Butt, Faizan Tahir / Phung, Bao Toan / Yeoh, Guan Heng / Yasin, Ghulam / Akram, Shakeel / Bhutta, Muhammad Shoaib / Hussain, Shahid / Anh Nguyen, Tuan

    Polymers

    2020  Volume 12, Issue 3

    Abstract: ...

    Abstract *
    Language English
    Publishing date 2020-03-05
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527146-5
    ISSN 2073-4360 ; 2073-4360
    ISSN (online) 2073-4360
    ISSN 2073-4360
    DOI 10.3390/polym12030582
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Extensive Pyoderma Gangrenosum: A Challenging Diagnosis and Literature Review of Management.

    Yasin, Faizan / Assad, Salman / Zahid, Mehr / Malik, Shuja A

    Cureus

    2017  Volume 9, Issue 7, Page(s) e1486

    Abstract: Pyoderma gangrenosum is a very rare, non-infectious leukocytic dermatosis, which is often associated with an underlying systemic disease. It is usually diagnosed based on the apparent clinical findings and by excluding other causes of ulcerative skin ... ...

    Abstract Pyoderma gangrenosum is a very rare, non-infectious leukocytic dermatosis, which is often associated with an underlying systemic disease. It is usually diagnosed based on the apparent clinical findings and by excluding other causes of ulcerative skin diseases. Treatment modality includes the use of systemic steroids and oral steroids. Immunosuppressive agents, such as cyclosporine and mycophenolate mofetil, can also be added if it fails to respond to steroids. We report a case of pyoderma gangrenosum in an 85-year-old female who presented in the inpatient facility with rapidly enlarging necrotic, ulcerative lesions with accompanying fever. She was managed with systemic steroids to which she responded well. This led to the arrest of the initially progressive lesions with some residual scarring.
    Language English
    Publishing date 2017-07-18
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.1486
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Combination Therapy for Multidrug-Resistant Klebsiella Pneumoniae Urinary Tract Infection.

    Yasin, Faizan / Assad, Salman / Talpur, Abdul Subhan / Zahid, Mehr / Malik, Shuja A

    Cureus

    2017  Volume 9, Issue 7, Page(s) e1503

    Abstract: Hospital-acquired multidrug-resistant (MDR) Klebsiella infection is posing a significant challenge to physicians all around the world. The spread of multiple antibiotic resistance among various members of bacteria continues to be a significant clinical ... ...

    Abstract Hospital-acquired multidrug-resistant (MDR) Klebsiella infection is posing a significant challenge to physicians all around the world. The spread of multiple antibiotic resistance among various members of bacteria continues to be a significant clinical threat. Antibiotic susceptibility testing is the initial step in optimizing the appropriate antibiotic therapy for infections with MDR Klebsiella. We report a case of MDR Klebsiella urinary tract infection (UTI) in a patient following a trimalleolar fracture, which was appropriately treated with a combination of amikacin and meropenem.
    Language English
    Publishing date 2017-07-22
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.1503
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Simulation and Experimental Investigation on Carbonized Tracking Failure of EPDM/BN-based Electrical Insulation

    Muhammad Tariq Nazir / Faizan Tahir Butt / Bao Toan Phung / Guan Heng Yeoh / Ghulam Yasin / Shakeel Akram / Muhammad Shoaib Bhutta / Shahid Hussain / Tuan Anh Nguyen

    Polymers, Vol 12, Iss 3, p

    2020  Volume 582

    Abstract: Correspondence: tariq [.] ...

    Abstract * Correspondence: tariq [.]
    Keywords n/a ; Organic chemistry ; QD241-441
    Language English
    Publishing date 2020-03-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article: Acute Liver Injury Induced by Synthetic Cannabinoid Abuse.

    Shahbaz, Amir / Gaviria, Rafael Eduardo Eee / Shahid, Muhammad Faizan / Yasin, Muhammad Awais / Ashraf, Attique / Zaman, Muhammad A

    Cureus

    2018  Volume 10, Issue 9, Page(s) e3257

    Abstract: Synthetic cannabinoid abuse can manifest with an array of unpredictable reactions ranging from sedation to hallucinations, psychosis, and seizures. Acute liver injury associated with the synthetic cannabinoid use is a rare complication. We present a case ...

    Abstract Synthetic cannabinoid abuse can manifest with an array of unpredictable reactions ranging from sedation to hallucinations, psychosis, and seizures. Acute liver injury associated with the synthetic cannabinoid use is a rare complication. We present a case of a 22-year-old homeless male presented with abdominal pain and vomiting. He admitted regular synthetic cannabinoid use, and binge alcohol use once a week. Physical examination was remarkable only for mild icterus. The laboratory result shows abnormal liver functions tests. Viral, autoimmune, metabolic and other toxic etiologies of liver injury were ruled out. The acute liver injury was deemed to be secondary to synthetic cannabinoids toxicity. Spice-induced liver injury remains a diagnosis of exclusion after all other identifiable causes ruled out. Clinicians should have a high index of suspicion for synthetic cannabinoid abuse in a patient with acute hepatotoxicity who had a history of polysubstance abuse.
    Language English
    Publishing date 2018-09-04
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.3257
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Quantifying cognition and fatigue to enhance the sensitivity of the EDSS during relapses.

    Morrow, Sarah A / Conway, Devon / Fuchs, Tom / Wojcik, Curtis / Unverdi, Mahmut / Yasin, Faizan / Pol, Jeta / Eckert, Sveltlana / Hojnacki, David H / Dwyer, Michael / Zivadinov, Robert / Weinstock-Guttman, Bianca / Benedict, Ralph Hb

    Multiple sclerosis (Houndmills, Basingstoke, England)

    2020  Volume 27, Issue 7, Page(s) 1077–1087

    Abstract: Background: Cognition is affected by relapses in persons with multiple sclerosis (PwMS), yet the Expanded Disability Status Scale (EDSS) does not readily detect cognitive changes.: Objective: The objective of this study is to improve the detection of ...

    Abstract Background: Cognition is affected by relapses in persons with multiple sclerosis (PwMS), yet the Expanded Disability Status Scale (EDSS) does not readily detect cognitive changes.
    Objective: The objective of this study is to improve the detection of cognitive decline during relapses, by incorporating the Symbol Digit Modalities Test (SDMT) into the cerebral Functional System Score (CFSS) of the EDSS.
    Methods: This prospective study recruited PwMS from three dedicated MS centers. All subjects had EDSS, SDMT, and Fatigue Severity Scale (FSS) administered. Subjects experiencing a relapse were assigned to the relapse group (RG). Matched controls from the larger cohort were assigned to the stable group (SG). RG and SG subjects underwent the same evaluation at relapse and 3 months later. Our main outcomes were a modified CFSS (m-CFSS) and modified EDSS (m-EDSS), incorporating SDMT and FSS, accounting for cognitive performance and fatigue rating, during relapse.
    Results: The full cohort included 592 subjects; 80 qualified for RG and 72 were matched to the SG. The m-CFSS was significantly higher than CFSS at baseline (median = 2 vs. median = 0,
    Conclusion: This study demonstrates that incorporating the SDMT and FSS improves the accuracy of the EDSS, by accounting for cognitive changes, during relapse activity.
    MeSH term(s) Cognition ; Disability Evaluation ; Fatigue/diagnosis ; Humans ; Multiple Sclerosis ; Neuropsychological Tests ; Prospective Studies ; Recurrence
    Language English
    Publishing date 2020-12-01
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1290669-4
    ISSN 1477-0970 ; 1352-4585
    ISSN (online) 1477-0970
    ISSN 1352-4585
    DOI 10.1177/1352458520973618
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Breast Cancer Metastases to the Gastrointestinal Tract Presenting with Anemia and Intra-abdominal Bleed.

    Khan, Idrees / Malik, Rehan / Khan, Amina / Assad, Salman / Zahid, Mehr / Sohail, Muhammad Saad / Yasin, Faizan / Qavi, Ahmed H

    Cureus

    2017  Volume 9, Issue 7, Page(s) e1429

    Abstract: Signet ring adenocarcinoma of the breast with synchronous metastasis to the gastrointestinal (GI) tract is a rare occurrence, typically presenting with abdominal pain, dyspepsia, or GI bleed. We report a case of metastatic breast cancer presenting with a ...

    Abstract Signet ring adenocarcinoma of the breast with synchronous metastasis to the gastrointestinal (GI) tract is a rare occurrence, typically presenting with abdominal pain, dyspepsia, or GI bleed. We report a case of metastatic breast cancer presenting with a complaint of anemia. A further diagnostic evaluation revealed generalized lymphadenopathy, nodular thickening of the urinary bladder wall, bone lesions, and enlarged pancreas. Biopsies from the lymph nodes, pancreatic biopsy, and bladder nodule all revealed a signet cell carcinoma. An upper and lower GI endoscopy revealed multiple ulcerated gastric mucosal nodules and polypoid folds in the cecum and proximal ascending colon; the biopsies from these lesions were also positive for signet ring cell adenocarcinoma.
    Language English
    Publishing date 2017-07-06
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.1429
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Recovery of cognitive function after relapse in multiple sclerosis.

    Benedict, Ralph Hb / Pol, Jeta / Yasin, Faizan / Hojnacki, David / Kolb, Channa / Eckert, Svetlana / Tacca, Beth / Drake, Allison / Wojcik, Curtis / Morrow, Sarah A / Jakimovski, Dejan / Fuchs, Tom A / Dwyer, Michael G / Zivadinov, Robert / Weinstock-Guttman, Bianca

    Multiple sclerosis (Houndmills, Basingstoke, England)

    2020  Volume 27, Issue 1, Page(s) 71–78

    Abstract: Background: Cognitive impairment is common in multiple sclerosis (MS) but its manifestation as acute disease activity is underappreciated.: Objective: The aim of this study is to examine recovery after MS relapse on multiple tests of cognitive and ... ...

    Abstract Background: Cognitive impairment is common in multiple sclerosis (MS) but its manifestation as acute disease activity is underappreciated.
    Objective: The aim of this study is to examine recovery after MS relapse on multiple tests of cognitive and motor function and explore correlates of change with Expanded Disability Status Scale (EDSS), magnetic resonance imaging (MRI), and cognitive reserve.
    Methods: Fifty relapsing group (RG) and matched stable participants were examined at baseline, during relapse, and at 3-month follow-up. Tests of cognitive processing speed (Symbol Digit Modalities Test (SDMT)) and consensus opinion measures of memory, ambulation, and manual dexterity were administered. All RG patients were treated with a 5-day course of Acthar Gel (5 mL/80 IU).
    Results: In RG patients, SDMT declined from 55.2 to 44.6 at relapse and recovered to 51.7, a slope differing from stable controls (
    Conclusion: These results replicate earlier reports of cognitive worsening during relapse in MS. Clinically meaningful improvements followed relapse on SDMT and ambulation. Cognitive decline during relapse can be appreciated on neurological exam but not patient-reported outcomes.
    MeSH term(s) Cognition ; Cognition Disorders ; Cognitive Dysfunction/etiology ; Humans ; Multiple Sclerosis/complications ; Multiple Sclerosis, Relapsing-Remitting/complications ; Multiple Sclerosis, Relapsing-Remitting/drug therapy ; Neuropsychological Tests ; Recurrence
    Language English
    Publishing date 2020-01-23
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1290669-4
    ISSN 1477-0970 ; 1352-4585
    ISSN (online) 1477-0970
    ISSN 1352-4585
    DOI 10.1177/1352458519898108
    Database MEDical Literature Analysis and Retrieval System OnLINE

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