Article ; Online: Combined IL-6 and JAK/STAT inhibition therapy in COVID-19-related sHLH, potential game changer.
British journal of haematology
2020 Volume 190, Issue 4, Page(s) 525–528
| MeSH term(s) | Aged ; Antibodies, Monoclonal, Humanized/administration & dosage ; COVID-19/blood ; COVID-19/complications ; COVID-19/diagnostic imaging ; COVID-19/drug therapy ; Drug Therapy, Combination ; Female ; Humans ; Interleukin-6/antagonists & inhibitors ; Janus Kinases/antagonists & inhibitors ; Lymphohistiocytosis, Hemophagocytic/blood ; Lymphohistiocytosis, Hemophagocytic/diagnostic imaging ; Lymphohistiocytosis, Hemophagocytic/drug therapy ; Lymphohistiocytosis, Hemophagocytic/etiology ; Male ; Middle Aged ; Nitriles ; Pyrazoles/administration & dosage ; Pyrimidines ; SARS-CoV-2 ; STAT Transcription Factors/analysis |
|---|---|
| Chemical Substances | Antibodies, Monoclonal, Humanized ; IL6 protein, human ; Interleukin-6 ; Nitriles ; Pyrazoles ; Pyrimidines ; STAT Transcription Factors ; ruxolitinib (82S8X8XX8H) ; Janus Kinases (EC 2.7.10.2) ; tocilizumab (I031V2H011) |
| Keywords | covid19 |
| Language | English |
| Publishing date | 2020-07-22 |
| Publishing country | England |
| Document type | Case Reports ; Journal Article |
| ZDB-ID | 80077-6 |
| ISSN | 1365-2141 ; 0007-1048 |
| ISSN (online) | 1365-2141 |
| ISSN | 0007-1048 |
| DOI | 10.1111/bjh.16966 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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