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Article ; Online: Training in medical communication competence through video-based e-learning: How effective are video modeling and video reflection?

Schick, Kristina / Reiser, Sabine / Janssen, Laura / Schacht, Laura / Pittroff, Sylvia Irene Donata / Dörfler, Eva / Klein, Evelyn / Roenneberg, Casper / Dinkel, Andreas / Fleischmann, Andreas / Berberat, Pascal O / Bauer, Johannes / Gartmeier, Martin

Patient education and counseling

2023 Volume 121, Page(s) 108132

Abstract: Objective: The present study investigated the efficacy of the didactic approaches of video modeling (VM, best-practice examples), video reflection (VR, problem-based approach), and the combination of both (VMR) in fostering medical communication ... ...

Abstract	Objective: The present study investigated the efficacy of the didactic approaches of video modeling (VM, best-practice examples), video reflection (VR, problem-based approach), and the combination of both (VMR) in fostering medical communication competence in a video-based digital learning environment. Methods: N = 126 third-year medical students who participated in the pre-post study were assigned to either the intervention groups (VM, VR, and VMR) or the wait-list control group. The efficacy of the three approaches was assessed by means of a situational judgment test (SJT) of medical communication competence. To investigate the differences between the wait-list control and the intervention groups (H Results: The planned contrasts showed that the VR condition significantly improved learning outcomes in comparison to the VM condition (H Conclusions: Our study provides promising evidence that VR fosters medical communication competence more effectively than VM. Practical implications: Medical students' learning in video-based digital environments can be facilitated by the use of interactive VR.
MeSH term(s)	Humans ; Computer-Assisted Instruction ; Clinical Competence ; Learning ; Students, Medical ; Communication
Language	English
Publishing date	2023-12-29
Publishing country	Ireland
Document type	Journal Article
ZDB-ID	605590-4
ISSN	1873-5134 ; 0738-3991
ISSN (online)	1873-5134
ISSN	0738-3991
DOI	10.1016/j.pec.2023.108132
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Article ; Online: Management-intensive grazing impacts on total Escherichia coli, E. coli O157:H7, and antibiotic resistance genes in a riparian stream.

Rubeck, Laura M / Wells, James E / Hanford, Kathryn J / Durso, Lisa M / Schacht, Walter H / Berry, Elaine D

The Science of the total environment

2022 Volume 817, Page(s) 152611

Abstract: The impacts of management-intensive grazing (MIG) of cattle on concentrations of total Escherichia coli, total suspended solids (TSS), and nitrate-nitrite nitrogen ( ... ...

Abstract	The impacts of management-intensive grazing (MIG) of cattle on concentrations of total Escherichia coli, total suspended solids (TSS), and nitrate-nitrite nitrogen (NO
MeSH term(s)	Animals ; Anti-Bacterial Agents/pharmacology ; Cattle ; Drug Resistance, Microbial/genetics ; Escherichia coli O157/genetics ; Feces
Chemical Substances	Anti-Bacterial Agents
Language	English
Publishing date	2022-01-04
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	121506-1
ISSN	1879-1026 ; 0048-9697
ISSN (online)	1879-1026
ISSN	0048-9697
DOI	10.1016/j.scitotenv.2021.152611
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Article: Management-intensive grazing impacts on total Escherichia coli, E. coli O157:H7, and antibiotic resistance genes in a riparian stream

Rubeck, Laura M. / Wells, James E. / Hanford, Kathryn J. / Durso, Lisa M. / Schacht, Walter H. / Berry, Elaine D.

Science of the total environment. 2022 Apr. 15, v. 817

2022

Abstract: ... Escherichia coli, total suspended solids (TSS), and nitrate-nitrite nitrogen (NO₃ + NO₂-N), and occurrence of E ... total E. coli in downstream water by 0.89 log₁₀ MPN/100 mL (p < 0.0001), and downstream total E. coli ... total E. coli and TSS concentrations in January and February (p < 0.05). For precipitation events during ...

Abstract	The impacts of management-intensive grazing (MIG) of cattle on concentrations of total Escherichia coli, total suspended solids (TSS), and nitrate-nitrite nitrogen (NO₃ + NO₂-N), and occurrence of E. coli O157:H7 and selected antibiotic resistance genes (ARGs) in stream water and/or sediments were evaluated. Cattle were grazed for two-week periods in May in each of three years. Overall, grazing increased total E. coli in downstream water by 0.89 log₁₀ MPN/100 mL (p < 0.0001), and downstream total E. coli concentrations were higher than upstream over all sampling intervals. Downstream TSS levels also increased (p ≤ 0.0294) during grazing. In contrast, there was a main effect of treatment for downstream NO₃ + NO₂-N to be lower than upstream (3.59 versus 3.70 mg/L; p = 0.0323). Overwintering mallard ducks increased total E. coli and TSS concentrations in January and February (p < 0.05). For precipitation events during the 24 h before sampling, each increase of 1.00 cm of rainfall increased total E. coli by 0.49 log₁₀ MPN/100 mL (p = 0.0005). In contrast, there was no association of previous 24 h precipitation volume on TSS (p = 0.1540), and there was a negative linear effect on NO₃ + NO₂-N (p = 0.0002). E. coli O157:H7 prevalence was low, but the pathogen was detected downstream up to 2½ months after grazing. Examination of ARGs sul1, ermB, blacₜₓ₋ₘ₋₃₂, and intI1 identified the need for additional research to understand the impact of grazing on the ecology of these resistance determinants in pasture-based cattle production. While E. coli remained higher in downstream water compared to upstream, MIG may reduce the magnitude of the downstream E. coli concentrations. Likewise, the MIG strategy may prevent large increases in TSS and NO₃ + NO₂-N concentrations during heavy rain events. Results indicate that MIG can limit the negative effects of cattle grazing on stream water quality.
Keywords	Anas platyrhynchos ; Escherichia coli O157 ; antibiotic resistance ; cattle ; cattle production ; ecology ; environment ; nitrogen ; overwintering ; pathogens ; rain ; streams ; water quality
Language	English
Dates of publication	2022-0415
Publishing place	Elsevier B.V.
Document type	Article
ZDB-ID	121506-1
ISSN	1879-1026 ; 0048-9697
ISSN (online)	1879-1026
ISSN	0048-9697
DOI	10.1016/j.scitotenv.2021.152611
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Article: Does vitamin E prevent gentamicin-induced ototoxicity?

Kharkheli, E / Kevanishvili, Z / Maglakelidze, T / Davitashvili, O / Schacht, J

Georgian medical news

2007 , Issue 146, Page(s) 14–17

Abstract: A randomized double-blind study was performed to check the protective efficacy of vitamin E against ... have been tested. Volunteers were randomly assigned to receive additionally either vitamin E or placebo ... The daily dosage of gentamicin amounted to 240 mg and that of vitamin E to 2800 mg. The treatment lasted 7 ...

Abstract	A randomized double-blind study was performed to check the protective efficacy of vitamin E against aminoglycoside ototoxicity. 52 patients scheduled for gentamicin therapy because of acute pulmonary infections have been tested. Volunteers were randomly assigned to receive additionally either vitamin E or placebo. The daily dosage of gentamicin amounted to 240 mg and that of vitamin E to 2800 mg. The treatment lasted 7 days. Hearing function was assessed before the start of medication and at the follow-up visit 6 to 8 weeks afterwards. Elevation of auditory thresholds occurred in similar number of patients in the vitamin-E and placebo groups and no statistically significant differences were found between. Vitamin E has been not confirmed thus to possess any protective action against gentamicin-induced ototoxicity.
MeSH term(s)	Adolescent ; Adult ; Aged ; Anti-Bacterial Agents/adverse effects ; Anti-Bacterial Agents/antagonists & inhibitors ; Anti-Bacterial Agents/therapeutic use ; Double-Blind Method ; Female ; Gentamicins/adverse effects ; Gentamicins/antagonists & inhibitors ; Gentamicins/therapeutic use ; Hearing Loss/chemically induced ; Hearing Loss/prevention & control ; Humans ; Male ; Middle Aged ; Placebos ; Pneumonia, Bacterial/drug therapy ; Vitamin E/therapeutic use
Chemical Substances	Anti-Bacterial Agents ; Gentamicins ; Placebos ; Vitamin E (1406-18-4)
Language	English
Publishing date	2007-05
Publishing country	Georgia (Republic)
Document type	Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
ZDB-ID	2443648-3
ISSN	1512-0112
ISSN	1512-0112
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Article ; Online: Characterisation of Prognosis and Invasion of Cutaneous Squamous Cell Carcinoma by Podoplanin and E-Cadherin Expression.

Hesse, Kristina / Satzger, Imke / Schacht, Vivien / Köther, Brigitta / Hillen, Uwe / Klode, Joachim / Schaper, Katrin / Gutzmer, Ralf

Dermatology (Basel, Switzerland)

2016 Volume 232, Issue 5, Page(s) 558–565

Abstract: ... immunohistochemical analyses of E-cadherin (marker for collective cancer invasion) and podoplanin (marker ... Immunohistochemical results were retrospectively correlated with clinical data.: Results: E-cadherin was highly ... invasion. However, E-cadherin was downregulated in poorly differentiated cSCC and lymph node metastases ...

Abstract	Background: Around 5% of all cutaneous squamous cell carcinoma (cSCC) metastasise. Metastases usually locate in regional skin and lymph nodes, suggesting collective cancer invasion. The cellular level of tumour invasion and prognostic parameters remain to be characterised. Methods: We performed immunohistochemical analyses of E-cadherin (marker for collective cancer invasion) and podoplanin (marker for epithelial-mesenchymal transition [EMT], single-cell invasion) expression in 102 samples of metastatic and non-metastatic cSCC and 18 corresponding skin and lymph node metastases to characterise the invasion of cSCC. Immunohistochemical results were retrospectively correlated with clinical data. Results: E-cadherin was highly expressed in metastatic and non-metastatic cSCC and skin metastases. This suggests collective cancer invasion. However, E-cadherin was downregulated in poorly differentiated cSCC and lymph node metastases, suggesting partial EMT. Podoplanin was significantly upregulated in metastatic (p = 0.002) and poorly differentiated (p = 0.003) cSCC. Overexpression of podoplanin represented a statistically independent prognostic factor for disease-free survival (p = 0.014). Conclusion: Collective cancer invasion is likely in cSCC. In lymph node metastases and poorly differentiated cSCC, partial EMT is possible. Podoplanin is an independent prognostic parameter for metastasis.
MeSH term(s)	Biomarkers, Tumor/analysis ; Cadherins/analysis ; Carcinoma, Squamous Cell/chemistry ; Carcinoma, Squamous Cell/secondary ; Down-Regulation ; Epithelial-Mesenchymal Transition ; Humans ; Immunohistochemistry ; Lymphatic Metastasis ; Membrane Glycoproteins/analysis ; Neoplasm Grading ; Neoplasm Invasiveness ; Prognosis ; Retrospective Studies ; Skin Neoplasms/chemistry ; Skin Neoplasms/pathology ; Up-Regulation
Chemical Substances	Biomarkers, Tumor ; Cadherins ; Membrane Glycoproteins ; PDPN protein, human
Language	English
Publishing date	2016
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	1099692-8
ISSN	1421-9832 ; 1018-8665
ISSN (online)	1421-9832
ISSN	1018-8665
DOI	10.1159/000450920
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Book ; Conference proceedings: Geburtshilfe im Wandel

Hildebrandt, Sven / Schacht, Johanna / Cotiga, Alin

traumatische Geburtserfahrung als lebenslanger Belastungsfaktor - gesunde Geburtserfahrung als lebenslange Ressource : Berichte von der Jahrestagung der ISPPM in Kooperation mit dem Fachbereich Pflege und Gesundheit der Hochschule Fulda, 25.-27. Oktober 2019

2021

Institution	International Society for Pre- and Perinatal Psychology and Medicine
Event/congress	Annual Meeting of ISPPM (31., 2019, Fulda)
Author's details	herausgegeben von Sven Hildebrandt, Johanna Schacht und Alin Cotiga
Keywords	Geburt ; Psychisches Trauma
Subject	Psychische Traumatisierung ; Psychotrauma ; Trauma ; Entbindung ; Geburtsvorgang ; Niederkunft
Subject code	618.4019
Language	German ; English
Size	199 Seiten, Illustrationen, Diagramme, 21 cm
Publisher	Mattes Verlag
Publishing place	Heidelberg
Publishing country	Germany
Document type	Book ; Conference proceedings
HBZ-ID	HT021128916
ISBN	978-3-86809-167-0 ; 3-86809-167-X
Database	Catalogue ZB MED Medicine, Health

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Article: Characterisation of Prognosis and Invasion of Cutaneous Squamous Cell Carcinoma by Podoplanin and E-Cadherin Expression

Hesse, Kristina / Satzger, Imke / Schacht, Vivien / Köther, Brigitta / Hillen, Uwe / Klode, Joachim / Schaper, Katrin / Gutzmer, Ralf

Dermatology

2016 Volume 232, Issue 5, Page(s) 558–565

Abstract: ... immunohistochemical analyses of E-cadherin (marker for collective cancer invasion) and podoplanin (marker ... Immunohistochemical results were retrospectively correlated with clinical data. Results: E-cadherin was highly ... invasion. However, E-cadherin was downregulated in poorly differentiated cSCC and lymph node metastases ...

Institution	Skin Cancer Center Hannover, Department for Dermatology and Allergy, Hannover Medical School, Hannover, and Department for Dermatology, University Medical Center Essen, Essen, Germany
Abstract	Background: Around 5% of all cutaneous squamous cell carcinoma (cSCC) metastasise. Metastases usually locate in regional skin and lymph nodes, suggesting collective cancer invasion. The cellular level of tumour invasion and prognostic parameters remain to be characterised. Methods: We performed immunohistochemical analyses of E-cadherin (marker for collective cancer invasion) and podoplanin (marker for epithelial-mesenchymal transition [EMT], single-cell invasion) expression in 102 samples of metastatic and non-metastatic cSCC and 18 corresponding skin and lymph node metastases to characterise the invasion of cSCC. Immunohistochemical results were retrospectively correlated with clinical data. Results: E-cadherin was highly expressed in metastatic and non-metastatic cSCC and skin metastases. This suggests collective cancer invasion. However, E-cadherin was downregulated in poorly differentiated cSCC and lymph node metastases, suggesting partial EMT. Podoplanin was significantly upregulated in metastatic (p = 0.002) and poorly differentiated (p = 0.003) cSCC. Overexpression of podoplanin represented a statistically independent prognostic factor for disease-free survival (p = 0.014). Conclusion: Collective cancer invasion is likely in cSCC. In lymph node metastases and poorly differentiated cSCC, partial EMT is possible. Podoplanin is an independent prognostic parameter for metastasis.
Keywords	E-cadherin ; Metastasis ; Collective invasion ; Epithelial-mesenchymal transition ; Podoplanin ; Cutaneous squamous cell carcinoma
Language	English
Publishing date	2016-11-23
Publisher	S. Karger AG
Publishing place	Basel, Switzerland
Document type	Article
Note	Original Paper
ZDB-ID	1099692-8
ISSN	1421-9832 ; 1018-8665
ISSN (online)	1421-9832
ISSN	1018-8665
DOI	10.1159/000450920
Database	Karger publisher's database

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Article ; Online: Motivated attention and task relevance in the processing of cross-modally associated faces: Behavioral and electrophysiological evidence.

Ziereis, Annika / Schacht, Anne

Cognitive, affective & behavioral neuroscience

2023 Volume 23, Issue 5, Page(s) 1244–1266

Abstract: ... restricted to the explicit, i.e., valence-classification, task. These findings highlight the importance ...

Abstract	It has repeatedly been shown that visually presented stimuli can gain additional relevance by their association with affective stimuli. Studies have shown effects of associated affect in event-related potentials (ERP) like the early posterior negativity (EPN), late positive complex (LPC), and even earlier components as the P1 or N170. However, findings are mixed as to the extent associated affect requires directed attention to the emotional quality of a stimulus and which ERP components are sensitive to task instructions during retrieval. In this preregistered study ( https://osf.io/ts4pb ), we tested cross-modal associations of vocal affect-bursts (positive, negative, neutral) to faces displaying neutral expressions in a flash-card-like learning task, in which participants studied face-voice pairs and learned to correctly assign them to each other. In the subsequent EEG test session, we applied both an implicit ("old-new") and explicit ("valence-classification") task to investigate whether the behavior at retrieval and neurophysiological activation of the affect-based associations were dependent on the type of motivated attention. We collected behavioral and neurophysiological data from 40 participants who reached the preregistered learning criterium. Results showed EPN effects of associated negative valence after learning and independent of the task. In contrast, modulations of later stages (LPC) by positive and negative associated valence were restricted to the explicit, i.e., valence-classification, task. These findings highlight the importance of the task at different processing stages and show that cross-modal affect can successfully be associated to faces.
MeSH term(s)	Humans ; Electroencephalography/methods ; Evoked Potentials/physiology ; Emotions/physiology ; Learning/physiology ; Facial Expression
Language	English
Publishing date	2023-06-23
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2029088-3
ISSN	1531-135X ; 1530-7026
ISSN (online)	1531-135X
ISSN	1530-7026
DOI	10.3758/s13415-023-01112-5
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Book ; Conference proceedings: Bindung und Geburt im transgenerationalen Kontext

Hildebrandt, Sven / Schacht, Johanna

Geburt als Resilienzfaktor seelischer Gesundheit - seelische Gesundheit als Resilienzfaktor der Geburt

2017

Institution	International Society for Pre- and Perinatal Psychology and Medicine
Event/congress	Bindung und Geburt im Transgenerationalen Kontext. Geburt als Resilienzfaktor Seelischer Gesundheit, Seelische Gesundheit als Resilienzfaktor der Geburt (2016, Stolpen)
Author's details	herausgegeben von Sven Hildebrandt, Johann Schacht, Helga Blazy und Wolfgang Bott
Language	German
Size	201 Seiten
Publisher	Mattes Verlag
Publishing place	Heidelberg
Publishing country	Germany
Document type	Book ; Conference proceedings
Note	Dokumentation der 28. Jahrestagung der ISPPM 2016 in Stolpen (Vortitelseite und Einführung)
HBZ-ID	HT019458761
ISBN	978-3-86809-116-8 ; 3-86809-116-5
Database	Catalogue ZB MED Medicine, Health

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2017 A 1621	available for loan (reading room)	Lesesaal EG

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Article ; Online: German fishery's adaptation to historic events, Western Baltic Sea, 1890-1950.

Schacht, Karoline / Voss, Rudi

Ambio

2022 Volume 52, Issue 1, Page(s) 155–170

Abstract: ... e.g. climate change) have emerged instead. We conclude that today's fisheries management needs ...

Abstract	Marine social-ecological systems (SES) have been providing important cultural, social, and economic services for many centuries. They are, however, increasingly threatened by fast changing environmental, ecological, and socio-economic conditions. As historical marine research is increasingly developing into a multidisciplinary endeavour, it offers outstanding points of departure to analyse historic events and the response and adaptation of the respective SES. Such knowledge helps to inform today's fisheries management and promotes successful management of changing ecosystems. Here, we compile and analyse historical data (1890-1950) of the German Western Baltic Sea fishery SES. This period is characterised by a series of strong impacts due to political, technological, economic, and ecological changes, such as two world wars, a global economic crisis, and other economic or ecological disasters. In our opinion, potential negative effects of those events were in the past attenuated by the system's high capacity to adapt. However, most of the fishers´ historic options on how to respond and adapt have recently become no longer available. New threats (e.g. climate change) have emerged instead. We conclude that today's fisheries management needs to integrate options of adaptation by exhausting all present or future opportunities. Adaptive fisheries management should not only focus on environmental change but need to include socio-economic change as well.
MeSH term(s)	Climate Change ; Ecosystem ; Fisheries/history ; Fisheries/trends ; Oceans and Seas ; Socioeconomic Factors
Language	English
Publishing date	2022-09-22
Publishing country	Sweden
Document type	Journal Article
ZDB-ID	120759-3
ISSN	1654-7209 ; 0044-7447
ISSN (online)	1654-7209
ISSN	0044-7447
DOI	10.1007/s13280-022-01768-2
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