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  1. Article ; Online: Piezo channels in the urinary system: Correspondence.

    Hu, Shuaishuai / Yao, Xudong

    Experimental & molecular medicine

    2023  Volume 55, Issue 12, Page(s) 2608

    MeSH term(s) Ion Channels ; Urinary Tract
    Chemical Substances Ion Channels
    Language English
    Publishing date 2023-12-01
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1328915-9
    ISSN 2092-6413 ; 1226-3613 ; 0378-8512
    ISSN (online) 2092-6413
    ISSN 1226-3613 ; 0378-8512
    DOI 10.1038/s12276-023-01124-8
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  2. Article ; Online: Piezo channels in the urinary system

    Shuaishuai Hu / Xudong Yao

    Experimental and Molecular Medicine, Vol 55, Iss 12, Pp 2608-

    Correspondence

    2023  Volume 2608

    Keywords Medicine ; R ; Biochemistry ; QD415-436
    Language English
    Publishing date 2023-12-01T00:00:00Z
    Publisher Nature Publishing Group
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Comment on "Organ-protective effect of angiotensin-converting enzyme 2 and its effect on the prognosis of COVID-19".

    Hu, Shuaishuai

    Journal of medical virology

    2020  Volume 92, Issue 9, Page(s) 1425–1426

    MeSH term(s) Angiotensin-Converting Enzyme 2 ; COVID-19 ; Humans ; Pandemics ; Prognosis ; SARS-CoV-2
    Chemical Substances Angiotensin-Converting Enzyme 2 (EC 3.4.17.23)
    Keywords covid19
    Language English
    Publishing date 2020-06-02
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 752392-0
    ISSN 1096-9071 ; 0146-6615
    ISSN (online) 1096-9071
    ISSN 0146-6615
    DOI 10.1002/jmv.25937
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  4. Article ; Online: The potential role of ubiquitination and deubiquitination in melanogenesis.

    Hu, Shuaishuai / Wang, Lu

    Experimental dermatology

    2023  Volume 32, Issue 12, Page(s) 2062–2071

    Abstract: Melanogenesis is a critical biochemical process in which melanocytes produce melanin, a crucial element involved in the formation of coat colour in mammals. According to several earlier studies, melanocytes' post-translational modifications of proteins ... ...

    Abstract Melanogenesis is a critical biochemical process in which melanocytes produce melanin, a crucial element involved in the formation of coat colour in mammals. According to several earlier studies, melanocytes' post-translational modifications of proteins primarily control melanogenesis. Among the many post-translational changes that can affect melanin production, ubiquitination and deubiquitination can keep melanin production going by changing how proteins that are related to melanin are broken down or kept stable. Ubiquitination and deubiquitination maintain ubiquitin homeostasis, which is a highly dynamic process in balance under the action of E3 ubiquitin ligase and deubiquitinating enzymes. However, the regulatory mechanisms underlying ubiquitination and deubiquitination in melanogenesis are yet to be thoroughly investigated. As a result, there has been a growing focus on exploring the potential correlation between melanogenesis, ubiquitination and deubiquitination. This study discusses the mechanisms of ubiquitination and deubiquitination in the context of melanogenesis, a crucial process for enhancing mammalian coat coloration and addressing pigment-related diseases.
    MeSH term(s) Animals ; Melanins/metabolism ; Ubiquitination ; Protein Processing, Post-Translational ; Ubiquitin-Protein Ligases/genetics ; Melanocytes/metabolism ; Mammals
    Chemical Substances Melanins ; Ubiquitin-Protein Ligases (EC 2.3.2.27)
    Language English
    Publishing date 2023-10-17
    Publishing country Denmark
    Document type Journal Article ; Review
    ZDB-ID 1130936-2
    ISSN 1600-0625 ; 0906-6705
    ISSN (online) 1600-0625
    ISSN 0906-6705
    DOI 10.1111/exd.14953
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  6. Article ; Online: Comment on “Organ‐protective effect of angiotensin‐converting enzyme 2 and its effect on the prognosis of COVID‐19”

    Hu, Shuaishuai

    Journal of Medical Virology

    2020  Volume 92, Issue 9, Page(s) 1425–1426

    Keywords Virology ; Infectious Diseases ; covid19
    Language English
    Publisher Wiley
    Publishing country us
    Document type Article ; Online
    ZDB-ID 752392-0
    ISSN 1096-9071 ; 0146-6615
    ISSN (online) 1096-9071
    ISSN 0146-6615
    DOI 10.1002/jmv.25937
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  7. Article ; Online: How Chromatin Stiffens Fibroblasts.

    Hu, Shuaishuai / Vondriska, Thomas M

    Current opinion in physiology

    2022  Volume 26

    Abstract: Fibroblasts are central to the acute and chronic response of tissues to stress: they are necessary for wound healing, involved in inflammatory responses and critical for long term remodeling of tissue. These diverse roles of fibroblasts arise from the ... ...

    Abstract Fibroblasts are central to the acute and chronic response of tissues to stress: they are necessary for wound healing, involved in inflammatory responses and critical for long term remodeling of tissue. These diverse roles of fibroblasts arise from the cells' ability to respond to internal and extracellular cues regarding the physical state of the host tissue. In this article, we review recent evidence for the role of chromatin as a sensor of cellular stress and chromatin-dependent gene regulatory events that may be essential for fibroblast activation in the setting of injury. This emerging evidence highlights chromatin structure and accessibility as features necessary for our understanding of how cell type-specific epigenomes sense and respond to stress.
    Language English
    Publishing date 2022-04-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 2918626-2
    ISSN 2468-8673 ; 2468-8681
    ISSN (online) 2468-8673
    ISSN 2468-8681
    DOI 10.1016/j.cophys.2022.100537
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  8. Article ; Online: Dipole moment regulation for enhancing internal electric field in covalent organic frameworks photocatalysts.

    Zhao, Xiaoying / Shang, Shuaishuai / Liu, Honglai / Peng, Changjun / Hu, Jun

    Chemosphere

    2024  Volume 356, Page(s) 141947

    Abstract: Covalent organic frameworks (COFs) have recently emerged as a kind of promising photocatalytic platform in addressing the growing threat of trace pollutants in aquatic environments. Along this, we propose a strategy of constructing internal electric ... ...

    Abstract Covalent organic frameworks (COFs) have recently emerged as a kind of promising photocatalytic platform in addressing the growing threat of trace pollutants in aquatic environments. Along this, we propose a strategy of constructing internal electric field (IEF) in COFs through the dipole moment regulation, which intrinsically facilitates the separation and transfer of photogenerated excitons. Two COFs of BTT-TZ-COF and BTT-TB-COF are developed by linking the electron-donor of benzotrithiophene (BTT) block and the electron-acceptor of triazine (TZ) or tribenzene (TB) block, respectively. DFT calculations demonstrate TZ block with larger dipole moment can achieve more efficient IEF due to the stronger electron-attractive force and hence narrower bandgap. Moreover, featuring the highly-order crystalline structure for accelerating photo-excitons transfer and rich porosity for facilitating the adsorption, BTT-TZ-COF exhibited an excellent universal performance of photocatalytic degradations of various dyes. Specifically, a superior photodegradation efficiency of 99% Rhodamine B (RhB) is achieved within 20 min under the simulated sunlight. Therefore, this convenient construction approach of enhanced IEF in COFs through rational regulation of the dipole moment can be a promising way to realize high photocatalytic activity.
    MeSH term(s) Catalysis ; Rhodamines/chemistry ; Metal-Organic Frameworks/chemistry ; Photolysis ; Photochemical Processes ; Adsorption ; Water Pollutants, Chemical/chemistry ; Electricity
    Chemical Substances Rhodamines ; rhodamine B (K7G5SCF8IL) ; Metal-Organic Frameworks ; Water Pollutants, Chemical
    Language English
    Publishing date 2024-04-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 120089-6
    ISSN 1879-1298 ; 0045-6535 ; 0366-7111
    ISSN (online) 1879-1298
    ISSN 0045-6535 ; 0366-7111
    DOI 10.1016/j.chemosphere.2024.141947
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  9. Article ; Online: Modulating the Primary and Secondary Coordination Spheres of Single Ni(II) Sites in Metal-Organic Frameworks for Boosting Photocatalysis.

    Yang, Ge / Wang, Denan / Wang, Yang / Hu, Wenhui / Hu, Shuaishuai / Jiang, Jun / Huang, Jier / Jiang, Hai-Long

    Journal of the American Chemical Society

    2024  Volume 146, Issue 15, Page(s) 10798–10805

    Abstract: Though the coordination environment of single metal sites has been recognized to be of great importance in promoting catalysis, the influence of simultaneous precise modulation of primary and secondary coordination spheres on catalysis remains largely ... ...

    Abstract Though the coordination environment of single metal sites has been recognized to be of great importance in promoting catalysis, the influence of simultaneous precise modulation of primary and secondary coordination spheres on catalysis remains largely unknown. Herein, a series of single Ni(II) sites with altered primary and secondary coordination spheres have been installed onto metal-organic frameworks (MOFs) with UiO-67 skeleton, affording UiO-Ni-X-Y (X = S, O; Y = H, Cl, CF
    Language English
    Publishing date 2024-04-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3155-0
    ISSN 1520-5126 ; 0002-7863
    ISSN (online) 1520-5126
    ISSN 0002-7863
    DOI 10.1021/jacs.4c00972
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  10. Article ; Online: Differential intestinal effects of water and foodborne exposures of nano-TiO

    Wei, Shuaishuai / Xu, Peng / Mao, Yiran / Shi, Yuntian / Liu, Wei / Li, Saishuai / Tu, Zhihan / Chen, Liming / Hu, Menghong / Wang, Youji

    Chemosphere

    2024  Volume 355, Page(s) 141777

    Abstract: With the wide use of nanomaterials in daily life, nano-titanium dioxide (nano- ... ...

    Abstract With the wide use of nanomaterials in daily life, nano-titanium dioxide (nano-TiO
    MeSH term(s) Animals ; Mytilus/metabolism ; Antioxidants/metabolism ; Water/metabolism ; Ecosystem ; Protein Carbonylation ; Temperature ; Intestines ; Water Pollutants, Chemical/metabolism ; Titanium/pharmacology
    Chemical Substances Antioxidants ; Water (059QF0KO0R) ; Water Pollutants, Chemical ; Titanium (D1JT611TNE)
    Language English
    Publishing date 2024-03-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 120089-6
    ISSN 1879-1298 ; 0045-6535 ; 0366-7111
    ISSN (online) 1879-1298
    ISSN 0045-6535 ; 0366-7111
    DOI 10.1016/j.chemosphere.2024.141777
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