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Article ; Online: Asociación entre la variación de glóbulos blancos y las manifestaciones clínicas, anticuerpos e infecciones en adultos con lupus eritematoso sistémico

Belén María Virasoro / Cecilia Pisoni

Revista Argentina de Reumatología, Vol 33, Iss

2022 Volume 3

Abstract: ... de autoanticuerpos, manifestaciones clínicas e infecciones en pacientes con lupus eritematoso sistémico ...

Abstract	Introducción: la asociación de leucopenia, linfopenia y neutropenia con la presencia de autoanticuerpos, manifestaciones clínicas e infecciones en pacientes con lupus eritematoso sistémico (LES) no está bien establecida. Los objetivos de este estudio fueron analizar los cambios en los recuentos de leucocitos y linfocitos en pacientes con LES y su asociación con manifestaciones clínicas, autoanticuerpos y riesgo de infecciones. Materiales y métodos: se recolectaron retrospectivamente los valores de leucocitos, linfocitos y neutrófilos. Se agruparon a los pacientes en cinco categorías: recuento de glóbulos blancos normales, leucopenia (persistente o intermitente) y linfopenia (persistente o intermitente). Se registraron las manifestaciones clínicas, los autoanticuerpos acumulados, el daño, la mortalidad, las infecciones y los tratamientos inmunosupresores recibidos de cada paciente.
Keywords	leucopenia ; linfopenia ; neutropenia ; glóbulos blancos ; lupus eritematoso sistémico ; Medicine ; R
Language	English
Publishing date	2022-09-01T00:00:00Z
Publisher	Sociedad Argentina de Reumatologia
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Ecografia e artroscopia in contemporanea per lo studio dell'ambiente articolare: indicazioni e limiti.

De Lucia, O / Paresce, E / Murgo, A / Epis, O / Pisoni, L / Schito, E / Valcamonica, E / Piana, C / Fantini, F

Reumatismo

2007 Volume 59, Issue 2, Page(s) 146–152

Abstract: Arthroscopy is a mini-invasive technique that allows the direct observation of the joint cavity and the execution of diagnostic and therapeutic procedures; arthroscopy needs a very long learning-time curve as well as dedicated spaces and instruments. ... ...

Title translation	Simultaneous ultrasonography and arthroscopy for the study of the joint environment: indications and limits.
Abstract	Arthroscopy is a mini-invasive technique that allows the direct observation of the joint cavity and the execution of diagnostic and therapeutic procedures; arthroscopy needs a very long learning-time curve as well as dedicated spaces and instruments. Ultrasonography is an imaging technique that enables to perform an immediate extension of the standard physical examination. The opportunity to visualize soft tissues, to obtain multiplanar and dynamic images in real time makes this practice easy repeatable at low costs. Ultrasonography allows to detect a variety of changes during inflammatory processes. The wide experience in arthroscopy of rheumatic patients acquired through the years by our team at the G. Pini Institute led us to study in vivo, during arthroscopy, the correspondence between arthroscopic and ultrasonographic images. Up to now three knee arthroscopies have been conducted with the double equipment (ultrasonographic and arthroscopic devices) in operating room. In our experience, the combination of the two methods in operating room may improve the validation of ultrasonography with arthroscopy as gold standard, helps to train the ultrasonographer to give immediate answers in order to clear the doubts aroused by ultrasonographic images; it also allows the arthroscopist to visualize the deeper layers of the synovial membrane making double guided targeted biopsies possible. Limits are the complexity of the procedure (instruments, operators, spaces, training of the doctors), the loose of power-doppler signal with the blood tourniquet and the always difficult evaluation of cartilage.
MeSH term(s)	Arthroscopy ; Female ; Humans ; Joint Diseases/diagnostic imaging ; Joint Diseases/pathology ; Knee Joint/diagnostic imaging ; Knee Joint/pathology ; Male ; Middle Aged ; Ultrasonography
Language	Italian
Publishing date	2007-05-16
Publishing country	Italy
Document type	Journal Article
ZDB-ID	414816-2
ISSN	2240-2683 ; 0048-7449
ISSN (online)	2240-2683
ISSN	0048-7449
DOI	10.4081/reumatismo.2007.146
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Article ; Online: Addressing the different paces of climate and air quality combustion emissions across the world.

Monforti-Ferrario, Fabio / Crippa, Monica / Pisoni, Enrico

iScience

2023 Volume 27, Issue 1, Page(s) 108686

Abstract: Greenhouse gases (GHG) and air pollutants (AP) share several anthropic sources but evolve differently in time across the various regions of the globe. Fossil and biological fuel combustion is by far the single process producing the highest amounts of ... ...

Abstract	Greenhouse gases (GHG) and air pollutants (AP) share several anthropic sources but evolve differently in time across the various regions of the globe. Fossil and biological fuel combustion is by far the single process producing the highest amounts of both types of compounds. We have analyzed the paces of change of both GHG and AP emissions across the world and in some selected highly emitting regions using purposely designed indicators. We have observed that, overall, combustion processes are generally producing a lower amount of pollutants per unit of GHG emitted in 2018 than in 1970, with the noticeable exception of ammonia emissions in transport. Nevertheless, comparing countries at different development levels, evidence of possible further improvement clearly emerges, depending on the technological evolution of the most important emitting sectors and on the implementation of appropriate control measures and policies.
Language	English
Publishing date	2023-12-07
Publishing country	United States
Document type	Journal Article
ISSN	2589-0042
ISSN (online)	2589-0042
DOI	10.1016/j.isci.2023.108686
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Article: Active mobility versus motorized transport? User choices and benefits for the society

Pisoni, E. / Christidis, P. / Navajas Cawood, E.

Science of the total environment. 2022 Feb. 01, v. 806

2022

Abstract: Measures promoting active mobility – walking or cycling – are often seen as an effective strategy to meet multiple urban objectives. The advantages of such behavioural changes cover multiple dimensions at public and individual level, including positive ... ...

Abstract	Measures promoting active mobility – walking or cycling – are often seen as an effective strategy to meet multiple urban objectives. The advantages of such behavioural changes cover multiple dimensions at public and individual level, including positive impacts on health, safety, climate, economy, environment and air quality. However, there is still a considerable potential for increasing the uptake of active mobility in urban areas. This paper explores the determinants of active mobility choice and compares the demographic, socio-economic and cultural factors that influence it. The methodology combines extensive survey data, an EU-wide transport model and detailed indicators of external costs of transport with a Gradient Boosting Machine Learning approach. The model based scenarios quantify the benefit in terms of external costs savings from increasing active mobility shares. Such savings – at EU level, can reach the amount of 15 billion euro per year for a shift of 10% of trips to active mobility modes.
Keywords	air quality ; climate ; environment ; models ; society ; socioeconomics ; surveys
Language	English
Dates of publication	2022-0201
Publishing place	Elsevier B.V.
Document type	Article
ZDB-ID	121506-1
ISSN	1879-1026 ; 0048-9697
ISSN (online)	1879-1026
ISSN	0048-9697
DOI	10.1016/j.scitotenv.2021.150627
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Article ; Online: Audiovisual Processing Skills Before Cochlear Implantation Predict Postoperative Speech Recognition in Adults.

Moberly, Aaron C / Pisoni, David B / Tamati, Terrin N

Ear and hearing

2023 Volume 45, Issue 3, Page(s) 617–625

Abstract: ... to auditory cues (i.e., "visual enhancement" [VE]) during recognition of speech presented in a combined ...

Abstract	Objectives: Adults with hearing loss (HL) demonstrate greater benefits of adding visual cues to auditory cues (i.e., "visual enhancement" [VE]) during recognition of speech presented in a combined audiovisual (AV) fashion when compared with normal-hearing peers. For patients with moderate-to-profound sensorineural HL who receive cochlear implants (CIs), it is unclear whether the restoration of audibility results in a decrease in the VE provided by visual cues during AV speech recognition. Moreover, it is unclear whether increased VE during the experience of HL before CI is beneficial or maladaptive to ultimate speech recognition abilities after implantation. It is conceivable that greater VE before implantation contributes to the enormous variability in speech recognition outcomes demonstrated among patients with CIs. This study took a longitudinal approach to test two hypotheses: (H1) Adult listeners with HL who receive CIs would demonstrate a decrease in VE after implantation; and (H2) The magnitude of pre-CI VE would predict post-CI auditory-only speech recognition abilities 6 months after implantation, with the direction of that relation supporting a beneficial, redundant, or maladaptive effect on outcomes. Design: Data were collected from 30 adults at two time points: immediately before CI surgery and 6 months after device activation. Pre-CI speech recognition performance was measured in auditory-only (A-only), visual-only, and combined AV fashion for City University of New York (CUNY) sentences. Scores of VE during AV sentence recognition were computed. At 6 months after CI activation, participants were again tested on CUNY sentence recognition in the same conditions as pre-CI. H1 was tested by comparing post- versus pre-CI VE scores. At 6 months of CI use, additional open-set speech recognition measures were also obtained in the A-only condition, including isolated words, words in meaningful AzBio sentences, and words in AzBio sentences in multitalker babble. To test H2, correlation analyses were performed to assess the relation between post-CI A-only speech recognition scores and pre-CI VE scores. Results: Inconsistent with H1, after CI, participants did not demonstrate a significant decrease in VE scores. Consistent with H2, preoperative VE scores positively predicted postoperative scores of A-only sentence recognition for both sentences in quiet and in babble (rho = 0.40 to 0.45, p < 0.05), supporting a beneficial effect of pre-CI VE on post-CI auditory outcomes. Pre-CI VE was not significantly related to post-CI isolated word recognition. The raw pre-CI CUNY AV scores also predicted post-CI A-only speech recognition scores to a similar degree as VE scores. Conclusions: After implantation, CI users do not demonstrate a decrease in VE from before surgery. The degree of VE during AV speech recognition before CI positively predicts A-only sentence recognition outcomes after implantation, suggesting the potential value of AV testing of CI patients preoperatively to help predict and set expectations for postoperative outcomes.
MeSH term(s)	Adult ; Humans ; Cochlear Implantation ; Speech Perception/physiology ; Speech ; Cochlear Implants ; Hearing Loss, Sensorineural/surgery ; Hearing Loss/surgery ; Deafness/surgery
Language	English
Publishing date	2023-12-25
Publishing country	United States
Document type	Journal Article
ZDB-ID	603093-2
ISSN	1538-4667 ; 0196-0202
ISSN (online)	1538-4667
ISSN	0196-0202
DOI	10.1097/AUD.0000000000001450
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Article ; Online: Inequality in exposure to air pollutants: A new perspective.

Pisoni, E / Dominguez-Torreiro, M / Thunis, P

Environmental research

2022 Volume 212, Issue Pt B, Page(s) 113358

Abstract: In research and policy design we mainly use a 'population weighted average concentrations' perspective to study changes in air quality, to evaluate if past policies have been effective, or to assess the impact of future air quality plans. This angle is ... ...

Abstract	In research and policy design we mainly use a 'population weighted average concentrations' perspective to study changes in air quality, to evaluate if past policies have been effective, or to assess the impact of future air quality plans. This angle is useful and informative, but sometimes masks other important patterns. In this paper we propose to add, to the existing population weighted average point of view, a new indicator that brings to the fore the 'inequalities' in exposure. This inequality indicator is based on the Gini coefficient, usually applied in Economics and here considered to evaluate if exposure to air pollutants is equally distributed among population. A case study for this new indicator is then proposed, to assess the evolution of exposure to air pollutants in Europe from 2000 to 2018, in terms of both average exposure and inequality levels. The results show that using only average exposure metrics can mask other interesting patterns, and confirm the benefits of including this alternative perspective into the analysis.
MeSH term(s)	Air Pollutants/analysis ; Air Pollution/analysis ; Environmental Exposure/analysis ; Europe
Chemical Substances	Air Pollutants
Language	English
Publishing date	2022-04-23
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	205699-9
ISSN	1096-0953 ; 0013-9351
ISSN (online)	1096-0953
ISSN	0013-9351
DOI	10.1016/j.envres.2022.113358
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Article: Inequality in exposure to air pollutants: A new perspective

Pisoni, E. / Dominguez Torreiro, M. / Thunis, P.

Environmental research. 2022 Apr. 20,

2022

Abstract: In research and policy design we mainly use a ‘population weighted average concentrations’ perspective to study changes in air quality, to evaluate if past policies have been effective, or to assess the impact of future air quality plans. This angle is ... ...

Abstract	In research and policy design we mainly use a ‘population weighted average concentrations’ perspective to study changes in air quality, to evaluate if past policies have been effective, or to assess the impact of future air quality plans. This angle is useful and informative, but sometimes masks other important patterns. In this paper we propose to add, to the existing population weighted average point of view, a new indicator that brings to the fore the ‘inequalities’ in exposure. This inequality indicator is based on the Gini coefficient, usually applied in Economics and here considered to evaluate if exposure to air pollutants is equally distributed among population. A case study for this new indicator is then proposed, to assess the evolution of exposure to air pollutants in Europe from 2000 to 2018, in terms of both average exposure and inequality levels. The results show that using only average exposure metrics can mask other interesting patterns, and confirm the benefits of including this alternative perspective into the analysis.
Keywords	air quality ; case studies ; economics ; issues and policy ; research ; Europe
Language	English
Dates of publication	2022-0420
Publishing place	Elsevier Inc.
Document type	Article
Note	Pre-press version
ZDB-ID	205699-9
ISSN	1096-0953 ; 0013-9351
ISSN (online)	1096-0953
ISSN	0013-9351
DOI	10.1016/j.envres.2022.113358
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Article ; Online: Comment to the paper "Assessing nitrogen dioxide (NO

Pisoni, E / Van Dingenen, R

The Science of the total environment

2020 Volume 738, Page(s) 139853

Abstract: In this paper we critically review the work "Assessing nitrogen dioxide ( ... ...

Abstract	In this paper we critically review the work "Assessing nitrogen dioxide (NO
MeSH term(s)	Air Pollutants/analysis ; Air Pollution/analysis ; Betacoronavirus ; COVID-19 ; Coronavirus ; Coronavirus Infections ; Estrone/analogs & derivatives ; Humans ; Nitrogen Dioxide/analysis ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2
Chemical Substances	Air Pollutants ; Estrone (2DI9HA706A) ; Nitrogen Dioxide (S7G510RUBH) ; estropipate (SVI38UY019)
Keywords	covid19
Language	English
Publishing date	2020-06-01
Publishing country	Netherlands
Document type	Letter
ZDB-ID	121506-1
ISSN	1879-1026 ; 0048-9697
ISSN (online)	1879-1026
ISSN	0048-9697
DOI	10.1016/j.scitotenv.2020.139853
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Article ; Online: Neural Correlates of Semantic Interference and Phonological Facilitation in Picture Naming: A Systematic Review and Coordinate-Based Meta-analysis.

Arrigoni, Eleonora / Rappo, Eleonora / Papagno, Costanza / Romero Lauro, Leonor J / Pisoni, Alberto

Neuropsychology review

2024

Abstract: Semantic interference (SI) and phonological facilitation (PF) effects occur when multiple representations are co-activated simultaneously in complex naming paradigms, manipulating the context in which word production is set. Although the behavioral ... ...

Abstract	Semantic interference (SI) and phonological facilitation (PF) effects occur when multiple representations are co-activated simultaneously in complex naming paradigms, manipulating the context in which word production is set. Although the behavioral consequences of these psycholinguistic effects are well-known, the involved brain structures are still controversial. This paper aims to provide a systematic review and a coordinate-based meta-analysis of the available functional neuroimaging studies investigating SI and PF in picture naming paradigms. The included studies were fMRI experiments on healthy subjects, employing paradigms in which co-activations of representations were obtained by manipulating the naming context using semantically or phonologically related items. We examined the principal methodological aspects of the included studies, emphasizing the existing commonalities and discrepancies across single investigations. We then performed an exploratory coordinate-based meta-analysis of the reported activation peaks of neural response related to SI and PF. Our results consolidated previous findings regarding the involvement of the left inferior frontal gyrus and the left middle temporal gyrus in SI and brought out the role of bilateral inferior parietal regions in PF.
Language	English
Publishing date	2024-02-06
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	1062572-0
ISSN	1573-6660 ; 1040-7308
ISSN (online)	1573-6660
ISSN	1040-7308
DOI	10.1007/s11065-024-09631-9
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Article ; Online: Neural alterations underlying executive dysfunction in Parkinson's disease: A systematic review and coordinate-based meta-analysis of functional neuroimaging studies.

Arrigoni, Eleonora / Antoniotti, Paola / Bellocchio, Virginia / Veronelli, Laura / Corbo, Massimo / Pisoni, Alberto

Ageing research reviews

2024 Volume 95, Page(s) 102207

Abstract: Parkinson's Disease's (PD) neuropsychological profile is often characterized by altered performance in executive functions (EF) tasks, with a remarkable impact on patients' quality of life. To date, the available neuroimaging literature lacks conclusive ... ...

Abstract	Parkinson's Disease's (PD) neuropsychological profile is often characterized by altered performance in executive functions (EF) tasks, with a remarkable impact on patients' quality of life. To date, the available neuroimaging literature lacks conclusive evidence about neural patterns underlying EF deficits in PD. Here, we aimed to synthesize the results of PET/fMRI studies examining the differences in brain activation between PD patients and controls during EF tasks, focusing on the three main EF sub-components: cognitive flexibility, working memory, and response inhibition. We conducted a coordinate-based meta-analysis to assess the converging alterations in brain activity in PD patients compared to controls. We assessed the association between aberrant patterns of activity and the EF sub-domains. We found a significant association between hypoactivation patterns in PD converging at the level of the right inferior frontal gyrus in response inhibition tasks, whereas hypoactivation in the left inferior frontal gyrus was found in association with the cognitive flexibility domain. Our results confirm the existence of neural alterations in PD patients in relation to specific EF sub-domains.
MeSH term(s)	Humans ; Parkinson Disease/diagnostic imaging ; Quality of Life ; Cognitive Dysfunction/diagnostic imaging ; Cognitive Dysfunction/etiology ; Brain/diagnostic imaging ; Executive Function/physiology ; Functional Neuroimaging
Language	English
Publishing date	2024-01-26
Publishing country	England
Document type	Systematic Review ; Meta-Analysis ; Journal Article ; Review
ZDB-ID	2075672-0
ISSN	1872-9649 ; 1568-1637
ISSN (online)	1872-9649
ISSN	1568-1637
DOI	10.1016/j.arr.2024.102207
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