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  1. Article ; Online: Cutting investment in the social care workforce will undermine the NHS recovery plan.

    Gordon, Adam L / Elder, Andrew

    BMJ (Clinical research ed.)

    2023  Volume 381, Page(s) 861

    MeSH term(s) Humans ; State Medicine ; Workforce ; Investments
    Language English
    Publishing date 2023-04-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 1362901-3
    ISSN 1756-1833 ; 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    ISSN (online) 1756-1833
    ISSN 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    DOI 10.1136/bmj.p861
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Resolving the health and social care crisis requires a focus on care for older people.

    Gordon, Adam L / Dhesi, Jugdeep

    BMJ (Clinical research ed.)

    2023  Volume 380, Page(s) 97

    MeSH term(s) Humans ; Aged ; Social Support ; Crisis Intervention ; Focus Groups
    Language English
    Publishing date 2023-01-13
    Publishing country England
    Document type Editorial
    ZDB-ID 1362901-3
    ISSN 1756-1833 ; 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    ISSN (online) 1756-1833
    ISSN 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    DOI 10.1136/bmj.p97
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  3. Article ; Online: We know the skills doctors need to work with care home residents: now we need to think about how to deliver them.

    Gordon, Adam L / McCarthy, Lauren / Borley, Kayla / Carroll, Rachael

    The British journal of general practice : the journal of the Royal College of General Practitioners

    2024  Volume 74, Issue 741, Page(s) 148–149

    MeSH term(s) Humans ; Physicians ; Surveys and Questionnaires ; Internship and Residency
    Language English
    Publishing date 2024-03-27
    Publishing country England
    Document type Editorial
    ZDB-ID 1043148-2
    ISSN 1478-5242 ; 0035-8797 ; 0960-1643
    ISSN (online) 1478-5242
    ISSN 0035-8797 ; 0960-1643
    DOI 10.3399/bjgp24X736737
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    Zs.B 576: Show issues Location:
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  4. Article ; Online: Prescribing medications with indications: time to flip the script.

    Schiff, Gordon D / Lambert, Bruce L / Wright, Adam

    BMJ quality & safety

    2023  Volume 32, Issue 6, Page(s) 315–318

    MeSH term(s) Humans ; Patient Safety ; Ambulatory Care ; Publications
    Language English
    Publishing date 2023-03-22
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 2592909-4
    ISSN 2044-5423 ; 2044-5415
    ISSN (online) 2044-5423
    ISSN 2044-5415
    DOI 10.1136/bmjqs-2023-015923
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  5. Article ; Online: The use of frailty questionnaires in inpatients in two neurorehabilitation units in the East Midlands - A cross-sectional cohort study with follow-up to 1-year after discharge from inpatient rehabilitation.

    Edwards, Laura / Tesorero, Vina / Zonouzi, Fattaneh / Santullo, Piera / Owen, Phoebe / Gordon, Adam L

    The journal of the Royal College of Physicians of Edinburgh

    2024  , Page(s) 14782715241242509

    Abstract: Background: Frailty correlates with poor clinical outcomes and is not routinely assessed in neurorehabilitation inpatient settings.: Methods: We recruited adults from two neurorehabilitation units. We administered six validated tools for assessing ... ...

    Abstract Background: Frailty correlates with poor clinical outcomes and is not routinely assessed in neurorehabilitation inpatient settings.
    Methods: We recruited adults from two neurorehabilitation units. We administered six validated tools for assessing frailty and collected data around length of stay, discharge, readmission and change in rehabilitation outcome measures.
    Results: Seventy-eight participants aged between 31 and 84 years were recruited with a range of neurological diagnoses. Frailty prevalence ranged between 23% and 46%, depending on the scale used, with little agreement between tools. Frailty status did not correlate with age, gender, length of stay, discharge destination and rehabilitation outcome measures. One-year readmission was higher in participants rated as frail by the Frail-Non-Disabled Questionnaire, the FRESH-screening questionnaire and the Clinical Frailty Scale.
    Discussion: Frailty ascertainment was variable depending on the tool used. Three frailty indices predicted readmission rate at 1 year but no other outcome measures. Therefore, frailty tools may have limited utility in this clinical population.
    Language English
    Publishing date 2024-04-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 2866363-9
    ISSN 2042-8189 ; 0953-0932
    ISSN (online) 2042-8189
    ISSN 0953-0932
    DOI 10.1177/14782715241242509
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  6. Article ; Online: Whether from a position of strength or weakness, geriatric medicine has work to do to drive up standards in health care for older people.

    Gordon, Adam L / Martin, Finbarr / Mistry, Sarah / Harwood, Rowan H / Dhesi, Jugdeep

    Age and ageing

    2023  Volume 52, Issue 11

    MeSH term(s) Humans ; Aged ; Geriatrics ; Frailty ; Delivery of Health Care
    Language English
    Publishing date 2023-11-05
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 186788-x
    ISSN 1468-2834 ; 0002-0729
    ISSN (online) 1468-2834
    ISSN 0002-0729
    DOI 10.1093/ageing/afad208
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    Zs.A 877: Show issues Location:
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    Zs.MO 448: Show issues

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  7. Article ; Online: Preoperative Depression Screening for Primary Total Knee Arthroplasty: An Evaluation of Its Modifiability on Outcomes in Patients Who Have Depression.

    Gordon, Adam M / Magruder, Matthew L / Schwartz, Jake / Ng, Mitchell K / Erez, Orry / Mont, Michael A

    The Journal of arthroplasty

    2024  

    Abstract: Background: Few studies have evaluated preoperative depression screenings in patients who have depression. We studied whether depression screenings before total knee arthroplasty (TKA) were associated with lower: 1) medical complications; 2) emergency ... ...

    Abstract Background: Few studies have evaluated preoperative depression screenings in patients who have depression. We studied whether depression screenings before total knee arthroplasty (TKA) were associated with lower: 1) medical complications; 2) emergency department (ED) utilizations and readmissions; 3) implant complications; and 4) costs.
    Methods: A nationwide sample from January 1, 2010, to April 30, 2021, was collected using an insurance database. Depression patients were 1:1 propensity-score matched based on those who had (n = 29,009) and did not have (n = 29,009) preoperative depression screenings or psychotherapy visits within 3 months of TKA. A case-matched population who did not have depression was compared (n = 144,994). A 90-day period was used to compare complications and health-care utilization and 2-year follow-up for periprosthetic joint infections (PJIs) and implant survivorship. Costs were 90-day reimbursements. Logistic regression models computed odds ratios (ORs) of depression screening on dependent variables. P values less than .001 were significant.
    Results: Patients who did not receive preoperative screening were associated with higher medical complications (18.7 versus 5.2%, OR: 4.15, P < .0001) and ED utilizations (11.5 versus 3.2%, OR: 3.93, P < .0001) than depressed patients who received screening. Patients who had screening had lower medical complications (5.2 versus 5.9%, OR: 0.88, P < .0001) and ED utilizations compared to patients who did not have depression (3.2 versus 3.8%, OR: 0.87, P = .0001). Two-year PJI incidences (3.0 versus 1.3%, OR: 2.63, P < .0001) and TKA revisions (4.3 versus 2.1%, OR: 2.46, P < .0001) were greater in depression patients who were not screened preoperatively versus screened patients. Depression patients who had screening had lower PJIs (1.3 versus 1.8%, OR: 0.74, P < .0001) compared to nondepressed patients. Reimbursements ($13,949 versus $11,982; P < .0001) were higher in depression patients who did not have screening.
    Conclusions: Preoperative screening was associated with improved outcomes in depression patients.
    Level of evidence: III.
    Language English
    Publishing date 2024-02-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 632770-9
    ISSN 1532-8406 ; 0883-5403
    ISSN (online) 1532-8406
    ISSN 0883-5403
    DOI 10.1016/j.arth.2024.02.035
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    Zs.A 2134: Show issues Location:
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  8. Article ; Online: Impact of Provider-Facing Interventions to Reduce Opioid Use on Pain Related Outcomes in Primary Care: A Cluster Randomized Trial.

    Hardy, Clinton J / Cochran, Gerald / Howey, Whitney / Wright, Eric / Wasan, Ajay D / Gordon, Adam J / Kraemer, Kevin L

    Health services research and managerial epidemiology

    2024  Volume 11, Page(s) 23333928241240957

    Language English
    Publishing date 2024-04-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2805732-6
    ISSN 2333-3928 ; 2333-3928
    ISSN (online) 2333-3928
    ISSN 2333-3928
    DOI 10.1177/23333928241240957
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  9. Article ; Online: The Difficulties of Managing Pain in People Living with Frailty: The Potential for Digital Phenotyping.

    Collins, Jemima T / Walsh, David A / Gladman, John R F / Patrascu, Monica / Husebo, Bettina S / Adam, Esmee / Cowley, Alison / Gordon, Adam L / Ogliari, Giulia / Smaling, Hanneke / Achterberg, Wilco

    Drugs & aging

    2024  Volume 41, Issue 3, Page(s) 199–208

    Abstract: Pain and frailty are closely linked. Chronic pain is a risk factor for frailty, and frailty is a risk factor for pain. People living with frailty also commonly have cognitive impairment, which can make assessment of pain and monitoring of pain management ...

    Abstract Pain and frailty are closely linked. Chronic pain is a risk factor for frailty, and frailty is a risk factor for pain. People living with frailty also commonly have cognitive impairment, which can make assessment of pain and monitoring of pain management even more difficult. Pain may be sub-optimally treated in people living with frailty, people living with cognitive impairment and those with both these factors. Reasons for sub-optimal treatment in these groups are pharmacological (increased drug side effects, drug-drug interactions, polypharmacy), non-pharmacological (erroneous beliefs about pain, ageism, bidirectional communication challenges), logistical (difficulty in accessing primary care practitioners and unaffordable cost of drugs), and, particularly in cognitive impairment, related to communication difficulties. Thorough assessment and characterisation of pain, related sensations, and their functional, emotional, and behavioural consequences ("phenotyping") may help to enhance the assessment of pain, particularly in people with frailty and cognitive impairment, as this may help to identify who is most likely to respond to certain types of treatment. This paper discusses the potential role of "digital phenotyping" in the assessment and management of pain in people with frailty. Digital phenotyping is concerned with observable characteristics in digital form, such as those obtained from sensing-capable devices, and may provide novel and more informative data than existing clinical approaches regarding how pain manifests and how treatment strategies affect it. The processing of extensive digital and usual data may require powerful algorithms, but processing these data could lead to a better understanding of who is most likely to benefit from specific and targeted treatments.
    MeSH term(s) Humans ; Pain Management ; Frailty/complications ; Chronic Pain ; Cognitive Dysfunction ; Risk Factors
    Language English
    Publishing date 2024-02-24
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 1075770-3
    ISSN 1179-1969 ; 1170-229X
    ISSN (online) 1179-1969
    ISSN 1170-229X
    DOI 10.1007/s40266-024-01101-4
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  10. Article ; Online: Cyclable Variable Path Length Multilevel Structures for Lossless Ion Manipulations (SLIM) Platform for Enhanced Ion Mobility Separations.

    Huntley, Adam P / Hollerbach, Adam L / Norheim, Randolph V / Hamid, Ahmed M / Anderson, Gordon A / Garimella, Sandilya V B / Ibrahim, Yehia M

    Analytical chemistry

    2024  

    Abstract: Ion mobility-mass spectrometry (IMS-MS) is used to analyze complex samples and provide structural information on unknown compounds. As the complexity of samples increases, there is a need to improve the resolution of IMS-MS instruments to increase the ... ...

    Abstract Ion mobility-mass spectrometry (IMS-MS) is used to analyze complex samples and provide structural information on unknown compounds. As the complexity of samples increases, there is a need to improve the resolution of IMS-MS instruments to increase the rate of molecular identification. This work evaluated a cyclable and variable path length (and hence resolving power) multilevel Structures for Lossless Ion Manipulations (SLIM) platform to achieve a higher resolving power than what was previously possible. This new multilevel SLIM platform has eight separation levels connected by ion escalators, yielding a total path length of ∼88 m (∼11 m per level). Our new multilevel SLIM can also be operated in an "ion cycling" mode by utilizing a set of return ion escalators that transport ions from the eighth level back to the first, allowing even extendable path lengths (and higher IMS resolution). The platform has been improved to enhance ion transmission and IMS separation quality by reducing the spacing between SLIM boards. The board thickness was reduced to minimize the ions' escalator residence time. Compared to the previous generation, the new multilevel SLIM demonstrated better transmission for a set of phosphazene ions, especially for the low-mobility ions. For example, the transmission of
    Language English
    Publishing date 2024-02-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1508-8
    ISSN 1520-6882 ; 0003-2700
    ISSN (online) 1520-6882
    ISSN 0003-2700
    DOI 10.1021/acs.analchem.3c05594
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