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  1. Article: Wm. Lloyd Stackhouse & Robert E. Kinsman: A tale of two chiropractors.

    Brown, Douglas M

    The Journal of the Canadian Chiropractic Association

    2013  Volume 57, Issue 3, Page(s) 233–242

    Abstract: This paper reviews the story of two childhood friends, Dr. Wm. Lloyd Stackhouse and Dr. Robert E ...

    Abstract This paper reviews the story of two childhood friends, Dr. Wm. Lloyd Stackhouse and Dr. Robert E. Kinsman, who attended the Canadian Memorial Chiropractic College (CMCC) together, graduated in 1953 to form an enduring partnership that included their immediate relatives, and to this day persists as a supportive tribe.
    Language English
    Publishing date 2013-11-07
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 2093945-0
    ISSN 1715-6181 ; 0008-3194
    ISSN (online) 1715-6181
    ISSN 0008-3194
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: [Rezension von: Issues in US-EC trade relations, ed. by Robert E. Baldwin ..]

    Brown, Drusilla K

    Southern economic journal 56 ,1, S. 255-256

    1989  

    Author's details Drusilla K. Brown
    Keywords 49;40
    Language English
    Publisher Wiley Subscription Services, Inc
    Publishing place Hoboken, NJ
    Document type Article
    ZDB-ID 219272x ; 2067038-2
    ISSN 2325-8012 ; 0038-4038
    ISSN (online) 2325-8012
    ISSN 0038-4038
    Database ECONomics Information System

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  3. Article ; Online: COVID-19 and Early Post-Primary TB: Commonalities of Pathobiology in Pneumonitis and Therapies.

    Brown, Robert E / Hunter, Robert L

    Annals of clinical and laboratory science

    2023  Volume 53, Issue 1, Page(s) 153–158

    Abstract: Objective: Concurrent infection with COVID-19 and : Methods: Since morphoproteomics combines the disciplines of histopathology, molecular biology and protein chemistry to paint a portrait of the protein circuitry in diseased cells for the purpose of ... ...

    Abstract Objective: Concurrent infection with COVID-19 and
    Methods: Since morphoproteomics combines the disciplines of histopathology, molecular biology and protein chemistry to paint a portrait of the protein circuitry in diseased cells for the purpose of uncovering targets amenable to specific intervention [1], we used morphoproteomic analyses to study lung tissues of patients with early post-primary tuberculosis or COVID-19 infection.
    Results: These studies showed co-localization of the COVID-19 virus and
    Conclusion: The commonalities in these pathways suggest that they might be susceptible to adjunctive therapies with metformin and vitamin D3. This is supported by published studies that metformin and vitamin D3 could reduce the severity of both COVID-19 and early post-primary TB infections.
    MeSH term(s) Humans ; COVID-19 ; Mycobacterium tuberculosis ; Lung ; Tuberculosis/drug therapy ; Cholecalciferol
    Chemical Substances Cholecalciferol (1C6V77QF41)
    Language English
    Publishing date 2023-03-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 193092-8
    ISSN 1550-8080 ; 0091-7370 ; 0095-8905
    ISSN (online) 1550-8080
    ISSN 0091-7370 ; 0095-8905
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 942: Show issues Location:
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  4. Article ; Online: Letter to the Editor:

    Brown, Robert E

    Annals of clinical and laboratory science

    2021  Volume 51, Issue 4, Page(s) 587–588

    MeSH term(s) Alveolar Epithelial Cells/enzymology ; Alveolar Epithelial Cells/virology ; COVID-19/enzymology ; COVID-19/pathology ; Fatty Acid Synthase, Type I/metabolism ; Humans
    Chemical Substances FASN protein, human (EC 2.3.1.85) ; Fatty Acid Synthase, Type I (EC 2.3.1.85)
    Language English
    Publishing date 2021-03-02
    Publishing country United States
    Document type Letter
    ZDB-ID 193092-8
    ISSN 1550-8080 ; 0091-7370 ; 0095-8905
    ISSN (online) 1550-8080
    ISSN 0091-7370 ; 0095-8905
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  5. Article ; Online: Commentary:

    Brown, Robert E

    Annals of clinical and laboratory science

    2021  Volume 51, Issue 6, Page(s) 890–893

    Abstract: Due to the resurgence of COVID-19, understanding the biology of SARS-CoV-2 is an opportunity to develop adjuvant therapies that could target its pathobiology and lessen the severity of the COVID-19 infection so that our patients could survive. This ... ...

    Abstract Due to the resurgence of COVID-19, understanding the biology of SARS-CoV-2 is an opportunity to develop adjuvant therapies that could target its pathobiology and lessen the severity of the COVID-19 infection so that our patients could survive. This commentary serves to accomplish this by using published morphoproteomic findings with data mining of the medical literature to define the pathobiology of COVID-19 pneumonitis and provide combinatorial and relatively non-toxic adjuvant therapies that have been successful against this viral infection.
    MeSH term(s) COVID-19/diagnosis ; COVID-19/metabolism ; COVID-19/pathology ; Combined Modality Therapy/methods ; Combined Modality Therapy/trends ; Data Mining ; Diagnostic Tests, Routine/trends ; Humans ; Pneumonia/diagnosis ; Proteomics/methods ; SARS-CoV-2/metabolism ; SARS-CoV-2/pathogenicity
    Language English
    Publishing date 2021-12-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 193092-8
    ISSN 1550-8080 ; 0091-7370 ; 0095-8905
    ISSN (online) 1550-8080
    ISSN 0091-7370 ; 0095-8905
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  6. Book: Analysis of neural data

    Kass, Robert E. / Eden, Uri T. / Brown, Emery N.

    (Springer series in statistics)

    2014  

    Author's details Robert E. Kass ; Uri T. Eden ; Emery N. Brown
    Series title Springer series in statistics
    Keywords Neurosciences/Data processing ; Numerical analysis/Data processing
    Subject code 612.80285
    Language English
    Size XXV, 648 S. : Ill., graph. Darst., 24 cm
    Publisher Springer
    Publishing place New York u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT018211613
    ISBN 978-1-4614-9601-4 ; 9781461496021 ; 1-4614-9601-2 ; 1461496020
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2014 A 1147 available for loan (reading room) Lesesaal EG

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  7. Article ; Online: Introducing the new Controversies in Liver Transplantation Corner.

    Serper, Marina / Fortune, Brett E / Cardenas, Andres / Brown, Robert S

    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

    2024  

    Language English
    Publishing date 2024-04-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2006866-9
    ISSN 1527-6473 ; 1527-6465
    ISSN (online) 1527-6473
    ISSN 1527-6465
    DOI 10.1097/LVT.0000000000000371
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    Zs.A 4702: Show issues Location:
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  8. Article: The American Histories of President Trump: Beyond the Jacksonian Parallel

    Brown, Robert E.

    American behavioral scientist. 2022 Jan., v. 66, no. 1

    2022  

    Abstract: This article begins with a consideration of the putative parallels between the presidencies of Andrew Jackson, the nation’s 7th president, and Donald Trump, the 45th. Underlying Trump’s and his supporters’ partisan case for his Jacksonian populism and ... ...

    Abstract This article begins with a consideration of the putative parallels between the presidencies of Andrew Jackson, the nation’s 7th president, and Donald Trump, the 45th. Underlying Trump’s and his supporters’ partisan case for his Jacksonian populism and similarly volatile temperament is another argument explored in this article: that such a Jacksonian framing implicitly situates Trump in the pantheon of the nation’s greatest, most consequential presidents who have expanded the powers of the office itself. Several standards of judgment are adduced for the critical consideration of the Trump presidency as it nears the completion of its first term. The consequentialism of the Trump presidency is weighed against standards of ethics and the personality trait known as Machiavellianism.
    Keywords ethics ; personality ; scientists ; temperament
    Language English
    Dates of publication 2022-01
    Size p. 43-60.
    Publishing place SAGE Publications
    Document type Article
    ISSN 1552-3381
    DOI 10.1177/0002764220978270
    Database NAL-Catalogue (AGRICOLA)

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  9. Article: Early Lesion of Post-Primary Tuberculosis: Subclinical Driver of Disease and Target for Vaccines and Host-Directed Therapies.

    Brown, Robert E / Hunter, Robert L

    Pathogens (Basel, Switzerland)

    2021  Volume 10, Issue 12

    Abstract: The characteristic lesion of primary tuberculosis is the granuloma as is widely studied in human tissues and animal models. Post-primary tuberculosis is different. It develops only in human lungs and begins as a prolonged subclinical obstructive lobular ... ...

    Abstract The characteristic lesion of primary tuberculosis is the granuloma as is widely studied in human tissues and animal models. Post-primary tuberculosis is different. It develops only in human lungs and begins as a prolonged subclinical obstructive lobular pneumonia that slowly accumulates mycobacterial antigens and host lipids in alveolar macrophages with nearby highly sensitized T cells. After several months, the lesions undergo necrosis to produce a mass of caseous pneumonia large enough to fragment and be coughed out to produce a cavity or be retained as the focus of a post-primary granuloma. Bacteria grow massively on the cavity wall where they can be coughed out to infect new people. Here we extend these findings with the demonstration of secreted mycobacterial antigens, but not acid fast bacilli (AFB) of
    Language English
    Publishing date 2021-12-02
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2695572-6
    ISSN 2076-0817
    ISSN 2076-0817
    DOI 10.3390/pathogens10121572
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  10. Article ; Online: Approaches to Gene Modulation Therapy for ALS.

    Meijboom, Katharina E / Brown, Robert H

    Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics

    2022  Volume 19, Issue 4, Page(s) 1159–1179

    Abstract: Amyotrophic lateral sclerosis (ALS) is a devastating motor neuron disease for which there is currently no robust therapy. Recent progress in understanding ALS disease mechanisms and genetics in combination with innovations in gene modulation strategies ... ...

    Abstract Amyotrophic lateral sclerosis (ALS) is a devastating motor neuron disease for which there is currently no robust therapy. Recent progress in understanding ALS disease mechanisms and genetics in combination with innovations in gene modulation strategies creates promising new options for the development of ALS therapies. In recent years, six gene modulation therapies have been tested in ALS patients. These target gain-of-function pathology of the most common ALS genes, SOD1, C9ORF72, FUS, and ATXN2, using adeno-associated virus (AAV)-mediated microRNAs and antisense oligonucleotides (ASOs). Here, we review the latest clinical and preclinical advances in gene modulation approaches for ALS, including gene silencing, gene correction, and gene augmentation. These techniques have the potential to positively impact the direction of future research trials and transform ALS treatments for this grave disease.
    MeSH term(s) Humans ; Amyotrophic Lateral Sclerosis/genetics ; Amyotrophic Lateral Sclerosis/therapy ; Superoxide Dismutase-1/genetics ; C9orf72 Protein/genetics ; Oligonucleotides, Antisense/genetics ; Oligonucleotides, Antisense/therapeutic use ; MicroRNAs
    Chemical Substances Superoxide Dismutase-1 (EC 1.15.1.1) ; C9orf72 Protein ; Oligonucleotides, Antisense ; MicroRNAs
    Language English
    Publishing date 2022-09-06
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
    ZDB-ID 2316693-9
    ISSN 1878-7479 ; 1933-7213
    ISSN (online) 1878-7479
    ISSN 1933-7213
    DOI 10.1007/s13311-022-01285-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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