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  1. Article: Inflammation and Vascular Injury as the Basis of COVID-19 Skin Changes: Preliminary Analysis of 23 Patients from the Literature [Letter].

    Tatu, Alin Laurentiu / Nadasdy, Thomas / Bujoreanu, Florin Ciprian

    Clinical, cosmetic and investigational dermatology

    2021  Volume 14, Page(s) 185–186

    Language English
    Publishing date 2021-02-26
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2494852-4
    ISSN 1178-7015
    ISSN 1178-7015
    DOI 10.2147/CCID.S305847
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Chitin-lipid interactions and the potential relationship between Demodex and SARS-CoV-2.

    Tatu, Alin Laurentiu / Nadasdy, Thomas / Nwabudike, Lawrence Chukwudi

    Dermatologic therapy

    2021  Volume 34, Issue 3, Page(s) e14935

    Abstract: Already from the early days of the COVID-19 pandemic, regulatory agencies have attempted to ascertain the possible routes of SARS-CoV-2 viral transmission. It is hypothesized that the lipid bilayer that surrounds the SARS-CoV-2 improves its ability to ... ...

    Abstract Already from the early days of the COVID-19 pandemic, regulatory agencies have attempted to ascertain the possible routes of SARS-CoV-2 viral transmission. It is hypothesized that the lipid bilayer that surrounds the SARS-CoV-2 improves its ability to remain stable on sebum-rich skin and serves as another possible route of contracting the virus. One possible aspect of these observations that has yet to be explored in detail is what role arthropods that have been associated with human skin infestation, such as Demodecidae or Pyemotidae species, play in viral transmission. It seems likely that arthropod-coronavirus interactions may take place through the molecular attraction forces between the chitin found on the exoskeleton of mites commonly found on human skin and the lipids present on the viral envelope of the SARS-CoV-2. We believe this may mean that arthropods are currently an overlooked cofactor in viral infection which may have some important biomedical implications for both prevention and treatment.
    MeSH term(s) COVID-19 ; Chitin ; Humans ; Lipids ; Pandemics ; SARS-CoV-2
    Chemical Substances Lipids ; Chitin (1398-61-4)
    Language English
    Publishing date 2021-03-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1354801-3
    ISSN 1529-8019 ; 1396-0296
    ISSN (online) 1529-8019
    ISSN 1396-0296
    DOI 10.1111/dth.14935
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: New data about sexually transmitted COVID-19.

    Tatu, Alin Laurentiu / Nadasdy, Thomas / Nwabudike, Lawrence Chukwudi

    Dermatologic therapy

    2020  Volume 33, Issue 6, Page(s) e14426

    MeSH term(s) COVID-19 ; Female ; Humans ; Pregnancy ; Pregnant Women ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-11-01
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1354801-3
    ISSN 1529-8019 ; 1396-0296
    ISSN (online) 1529-8019
    ISSN 1396-0296
    DOI 10.1111/dth.14426
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Familial clustering of COVID-19 skin manifestations.

    Tatu, Alin Laurentiu / Nadasdy, Thomas / Bujoreanu, Florin Ciprian

    Dermatologic therapy

    2020  Volume 33, Issue 6, Page(s) e14181

    Abstract: The medical community in the past months has seen a flourishing of information related to the SARS-CoV-2 virus responsible for the COVID-19 pandemic. From the early days of the pandemic, the SARS-CoV-2 virus has been linked to multiple different types of ...

    Abstract The medical community in the past months has seen a flourishing of information related to the SARS-CoV-2 virus responsible for the COVID-19 pandemic. From the early days of the pandemic, the SARS-CoV-2 virus has been linked to multiple different types of skin involvement. To the best of our knowledge, we are the first to report on a case of familial clustering of a maculopapular COVID-19 rash. Eight persons presented COVID-19 symptoms, six were confirmed via SAR-CoV-2 chemoluminescent immunoassays, and the four related by blood presented skin manifestations. Although, it has not been fully established if the SARS-CoV-2 can in fact cause viral exanthems, our observations regarding the familial clustering and the temporal evolution seen in this family seem to present strong evidence of a viral exanthema related to SARS-CoV-2 infection.
    MeSH term(s) Adult ; Aged, 80 and over ; COVID-19/complications ; COVID-19/diagnosis ; COVID-19 Testing ; Family Health ; Female ; Humans ; Infant ; Luminescent Measurements ; Male ; Middle Aged ; SARS-CoV-2/isolation & purification ; Skin Diseases, Viral/diagnosis ; Skin Diseases, Viral/physiopathology
    Keywords covid19
    Language English
    Publishing date 2020-09-04
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 1354801-3
    ISSN 1529-8019 ; 1396-0296
    ISSN (online) 1529-8019
    ISSN 1396-0296
    DOI 10.1111/dth.14181
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Comments on "Does COVID-19 influence sexual behaviours?"

    Nadasdy, Thomas / Clatici, Victor Gabriel / Barinova, Elena / Tatu, Alin Laurentiu

    Dermatologic therapy

    2020  Volume 33, Issue 6, Page(s) e14083

    MeSH term(s) COVID-19 ; Health Behavior ; Humans ; SARS-CoV-2 ; Sexual Behavior
    Keywords covid19
    Language English
    Publishing date 2020-08-13
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1354801-3
    ISSN 1529-8019 ; 1396-0296
    ISSN (online) 1529-8019
    ISSN 1396-0296
    DOI 10.1111/dth.14083
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: New Antifibroblastic Medication in Dermatology: Could Nintedanib Treat Scarring?

    Cristodor, Patricia Liana / Nechifor, Alexandru / Fotea, Silvia / Nadasdy, Thomas / Bahloul, Yousef / Nicolescu, Alin Codrut / Tatu, Alin Laurentiu

    International journal of general medicine

    2022  Volume 15, Page(s) 7169–7172

    Abstract: There are a wide variety of disfiguring dermatological conditions whose pathologic substrate is represented by the unwanted deposition of collagen from dermal fibroblasts. Pirfenidone has demonstrated efficiency in the treatment of disordered collagen ... ...

    Abstract There are a wide variety of disfiguring dermatological conditions whose pathologic substrate is represented by the unwanted deposition of collagen from dermal fibroblasts. Pirfenidone has demonstrated efficiency in the treatment of disordered collagen production when applied topically. Due to a similar mechanism of action, we also hypothesize that a similar medication, nintedanib, might have similar applications. We also propose that a liposomal technology may assist in the penetration of nintedanib and enhance its clinical effects.
    Language English
    Publishing date 2022-09-12
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2452220-X
    ISSN 1178-7074
    ISSN 1178-7074
    DOI 10.2147/IJGM.S377073
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Familial clustering of COVID ‐19 skin manifestations

    Tatu, Alin Laurentiu / Nadasdy, Thomas / Bujoreanu, Florin Ciprian

    Dermatologic Therapy ; ISSN 1396-0296 1529-8019

    2020  

    Keywords Dermatology ; General Medicine ; covid19
    Language English
    Publisher Wiley
    Publishing country us
    Document type Article ; Online
    DOI 10.1111/dth.14181
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article: Familial clustering of COVID-19 skin manifestations

    Tatu, Alin Laurentiu / Nadasdy, Thomas / Bujoreanu, Florin Ciprian

    Dermatol Ther

    Abstract: The medical community in the past months has seen a flourishing of information related to the SARS-CoV-2 virus responsible for the COVID-19 pandemic. From the early days of the pandemic, the SARS-CoV-2 virus has been linked to multiple different types of ...

    Abstract The medical community in the past months has seen a flourishing of information related to the SARS-CoV-2 virus responsible for the COVID-19 pandemic. From the early days of the pandemic, the SARS-CoV-2 virus has been linked to multiple different types of skin involvement. To the best of our knowledge, we are the first to report on a case of familial clustering of a maculopapular COVID-19 rash. Eight persons presented COVID-19 symptoms, six were confirmed via SAR-CoV-2 chemoluminescent immunoassays, and the four related by blood presented skin manifestations. Although, it has not been fully established if the SARS-CoV-2 can in fact cause viral exanthems, our observations regarding the familial clustering and the temporal evolution seen in this family seem to present strong evidence of a viral exanthema related to SARS-CoV-2 infection.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #721122
    Database COVID19

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