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  1. Book ; Online ; E-Book: Practical biostatistics in translational healthcare

    Khakshooy, Allen M. / Chiappelli, Francesco

    2018  

    Author's details Allen M. Khakshooy, Francesco Chiappelli
    Keywords Dentistry ; Medicine ; General practice (Medicine) ; Nursing
    Subject code 610
    Language English
    Size 1 Online-Ressource (xviii, 227 Seiten), Illustrationen
    Publisher Springer
    Publishing place Berlin
    Publishing country Germany
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019761382
    ISBN 978-3-662-57437-9 ; 9783662574355 ; 3-662-57437-3 ; 3662574357
    DOI 10.1007/978-3-662-57437-9
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    Full text online

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  2. Book: Fundamentals of evidence-based health care and translational science

    Chiappelli, Francesco

    2014  

    Title variant Fundamentals of evidence-based health care and translational science
    Author's details Francesco Chiappelli
    Keywords Evidenz-basierte Medizin ; Klinische Medizin ; Grundlagenforschung
    Subject Evidence-based medicine ; Gutachtenbasierte Medizin ; Evidenzbasierte Medizin ; Grundlagentheorie
    Language English
    Size XXVII, 394 S. : Ill., graph. Darst., 235 mm x 155 mm
    Publisher Springer
    Publishing place Heidelberg u.a.
    Publishing country Germany
    Document type Book
    HBZ-ID HT018167589
    ISBN 978-3-642-41856-3 ; 3-642-41856-2 ; 9783642418570 ; 3642418570
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2014 A 1795 available for loan (reading room) Lesesaal EG

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  3. Book: Osteoimmunopathology

    Chiappelli, Francesco

    evidence-based perspectives from molecular biology to systems biology

    2011  

    Author's details Francesco Chiappelli
    Language English
    Size XII, 137 S. : Ill., graph. Darst.
    Publisher Springer
    Publishing place New York u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT016873863
    ISBN 978-1-4419-9495-0 ; 1-4419-9495-5
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2011 A 2486 order for loan Magazin

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  4. Book: Comparative effectiveness and efficacy research and analysis for practice (CEERAP)

    Chiappelli, Francesco

    applications in health care

    2012  

    Author's details Francesco Chiappelli ed
    Keywords Evidenz-basierte Medizin ; Therapieerfolg ; Evaluation
    Subject Evaluierung ; Therapie ; Behandlungserfolg ; Heilungserfolg ; Heilerfolg ; Evidence-based medicine ; Gutachtenbasierte Medizin ; Evidenzbasierte Medizin
    Language English
    Size XII, 194 S. : Ill., 24 cm
    Publisher Springer
    Publishing place Heidelberg u.a.
    Publishing country Germany
    Document type Book
    HBZ-ID HT017191894
    ISBN 978-3-642-23143-8 ; 3-642-23143-8 ; 9783642231445 ; 3642231446
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2012 A 1468 order for loan Magazin

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  5. Article: Evidence-based modalities in the management of Psoriasis and Psoriatic arthritis.

    Francesco, Chiappelli

    Bioinformation

    2023  Volume 19, Issue 6, Page(s) 679–684

    Abstract: Psoriasis is a waxing and waning skin disorder, often associated with a plethora of co-morbidities, including psoriatic arthritis (PsA), a severe form of chronic inflammatory arthritis. All forms of psoriasis and PsA are immune-mediated diseases where ... ...

    Abstract Psoriasis is a waxing and waning skin disorder, often associated with a plethora of co-morbidities, including psoriatic arthritis (PsA), a severe form of chronic inflammatory arthritis. All forms of psoriasis and PsA are immune-mediated diseases where the patient's immune system is overactive in the production of certain factors that stimulate and activate the function of certain immune cells. Recent evidence has uncovered an important role for cell-mediated immunity in the aetiology and course of psoriasis and PsA, with a critical role played by the pro-inflammatory IL-23/TH17 axis. Taken together, these new lines of evidence suggest new and improved therapeutic interventions for patients with psoriasis and PsA. The hypothesis-driven process of inquiry of the best available evidence and its implication, application and evaluation in the context of clinical practice pertains to the meta-science of evidence-based health care (EBHC). EBHC consists in the initial step of research synthesis and generation of the systematic review of the best available evidence, estimated both qualitatively and quantitatively (i.e., meta-analysis). Evidence-based decision-making, a process driven and controlled by the expertise of the clinician and by the clinical needs and personal wants of the patient, is the principal, most timely and critical aspect of evidence-based practice. Recent and systematic reviews for the treatment of psoriasis and PsA consistently updated for emerging new and revised data (i.e., living systematic reviews) confirm the efficacy and the effectiveness of methotrexate (MTX) in containing and controlling psoriasis. The outcomes of MTX intervention for PsA remain mixed and inconclusive.
    Language English
    Publishing date 2023-06-30
    Publishing country Singapore
    Document type Journal Article
    ZDB-ID 2203786-X
    ISSN 0973-2063
    ISSN 0973-2063
    DOI 10.6026/97320630019679
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book: Evidence-based practice: Toward optimizing clinical outcomes

    Chiappelli, Francesco

    2010  

    Author's details Francesco Chiappelli ... (ed.)
    Keywords Evidenz-basierte Medizin ; Therapieplan
    Subject Behandlungsplan ; Heilplan ; Algorithmus ; Entscheidungsfindung ; Entscheidungsprozess ; Clinical reasoning ; Evidence-based medicine ; Gutachtenbasierte Medizin ; Evidenzbasierte Medizin
    Language English
    Size XIV, 251 S. : Ill., graph. Darst.
    Publisher Springer
    Publishing place Heidelberg u.a.
    Publishing country Germany
    Document type Book
    HBZ-ID HT016463569
    ISBN 978-3-642-05024-4 ; 9783642050251 ; 3-642-05024-7 ; 3642050255
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2010 A 4059 order for loan Magazin

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  7. Article: Nipah: The looming post-covid pandemic.

    Sekimoto, Olivia / Chiappelli, Francesco

    Bioinformation

    2024  Volume 20, Issue 1, Page(s) 1–3

    Abstract: First identified as a pathogen in Malaysia and Singapore in 1999, Nipah virus (NiV) caused nearly 300 human cases and over 100 fatalities. It also killed about 1 million pigs. Three years later (2002), it was reported in Pteropus bats in Malaysia, in ... ...

    Abstract First identified as a pathogen in Malaysia and Singapore in 1999, Nipah virus (NiV) caused nearly 300 human cases and over 100 fatalities. It also killed about 1 million pigs. Three years later (2002), it was reported in Pteropus bats in Malaysia, in Cambodia & Thailand, (2005), and as far as Madagascar (2007) and Ghana (2008). India (Kerala) reported its first human NiV-caused fatalities in September 2023. Taken together, these trends emphasize its public health threat. In humans, NiV infection initially leads to fever, headache, body aches and muscle pain, nausea and vomiting. The symptoms rapidly evolve into sore throat, cough and atypical pneumonia leading to severe respiratory distress. The cadre of NiV-induced pathology (Nipah disease, NiD) then includes severe dizziness and drowsiness, progressive alteration in cognition and consciousness, acute encephalitis and seizures. Public health protocols (e.g., mask-wearing, quarantine), essential to contain and control CoViD-19, seem insufficient to contain NiD spread because NiV transmission occurs primarily via direct contacts with body fluids of infected carriers, but presumably not by airborne transmission. As in the case of SARS-C0V2, health care providers (i.e., physicians, dentists, nurses, dental assistants) are greatest risks not only of contracting but of spreading NiV infection. NiV is a high-pathogenicity pathogen, against which, at present, we have no anti-viral medications or preventive vaccine. Taken together, the evidence to date heightens the threat of an upcoming NiD pandemic.
    Language English
    Publishing date 2024-01-31
    Publishing country Singapore
    Document type Editorial
    ZDB-ID 2203786-X
    ISSN 0973-2063
    ISSN 0973-2063
    DOI 10.6026/973206300200001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Comments on "An insertion unique to SARS-CoV-2 exhibits super antigenic character strengthened by recent mutations" by Cheng MH et al.2020.

    Chiappelli, Francesco

    Bioinformation

    2020  Volume 16, Issue 6, Page(s) 474–476

    Keywords covid19
    Language English
    Publishing date 2020-06-30
    Publishing country Singapore
    Document type Journal Article
    ZDB-ID 2203786-X
    ISSN 0973-2063
    ISSN 0973-2063
    DOI 10.6026/97320630016474
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Comments on Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease by Dai et al.(2020).

    Chiappelli, Francesco

    Bioinformation

    2020  Volume 16, Issue 5, Page(s) 432–434

    Keywords covid19
    Language English
    Publishing date 2020-05-31
    Publishing country Singapore
    Document type Journal Article
    ZDB-ID 2203786-X
    ISSN 0973-2063
    ISSN 0973-2063
    DOI 10.6026/97320630016432
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Book: Manual of evidence based research for the health sciences

    Chiappelli, Francesco

    implication for clinical dentistry

    2008  

    Title variant Manual of evidence-based research for the health sciences
    Author's details Francesco Chiappelli, ed
    Keywords Dentistry / methods ; Evidence-Based Medicine / methods ; Research ; Evidence-based dentistry
    Subject code 617.6
    Language English
    Size X, 327 S. : Ill., graph. Darst., 26cm
    Publisher Nova Science Publ
    Publishing place New York
    Publishing country United States
    Document type Book
    HBZ-ID HT016208980
    ISBN 1-60021-885-7 ; 978-1-60021-885-9
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2010 A 477 order for loan Magazin

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    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

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