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Article: Navigating rare disease medications: A pharmacist's primer.

Shakeri, Ahmad / Abdul Aziz, Yasmin / Tadrous, Mina

Canadian pharmacists journal : CPJ = Revue des pharmaciens du Canada : RPC

2024 Volume 157, Issue 2, Page(s) 50–52

Language	English
Publishing date	2024-01-30
Publishing country	United States
Document type	Journal Article
ZDB-ID	2200008-2
ISSN	1913-701X ; 1715-1635
ISSN (online)	1913-701X
ISSN	1715-1635
DOI	10.1177/17151635241228274
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Article ; Online: Noise effect on soliton phenomena in fractional stochastic Kraenkel-Manna-Merle system arising in ferromagnetic materials.

Yasmin, Humaira / Alshehry, Azzh Saad / Ganie, Abdul Hamid / Shafee, Ahmad / Shah, Rasool

Scientific reports

2024 Volume 14, Issue 1, Page(s) 1810

Abstract: This work dives into the Conformable Stochastic Kraenkel-Manna-Merle System (CSKMMS), an important mathematical model for exploring phenomena in ferromagnetic materials. A wide spectrum of stochastic soliton solutions that include hyperbolic, ... ...

Abstract	This work dives into the Conformable Stochastic Kraenkel-Manna-Merle System (CSKMMS), an important mathematical model for exploring phenomena in ferromagnetic materials. A wide spectrum of stochastic soliton solutions that include hyperbolic, trigonometric and rational functions, is generated using a modified version of Extended Direct Algebraic Method (EDAM) namely r+mEDAM. These stochastic soliton solutions have practical relevance for describing magnetic field behaviour in zero-conductivity ferromagnets. By using Maple to generate 2D and 3D graphical representations, the study analyses how stochastic terms and noise impact these soliton solutions. Finally, this study adds to our knowledge of magnetic field behaviour in ferromagnetic materials by shedding light on the effect of noise on soliton processes inside the CSKMMS.
Language	English
Publishing date	2024-01-20
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-024-52211-3
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Article ; Online: Regulatory landscape and public perception for gene-edited bananas in the Southeast Asian region.

Mat Jalaluddin, Nurzatil Sharleeza / Ahmad Fuaad, Abdulah Al-Hadi / Othman, Rofina Yasmin

Transgenic research

2024

Abstract: Banana is a premier fruit crop in many parts of the world especially Southeast Asia. The demand for banana has contributed to significant national income to primary banana producers in the SEA region such as the Philippines, Indonesia, Thailand, Vietnam, ...

Abstract	Banana is a premier fruit crop in many parts of the world especially Southeast Asia. The demand for banana has contributed to significant national income to primary banana producers in the SEA region such as the Philippines, Indonesia, Thailand, Vietnam, and Malaysia. However, the widely traded banana industry is plagued by numerous threats including pests and diseases, post-harvest issues and extreme climate vulnerability. To address these challenges, new breeding techniques such as gene editing have been explored for breeding programs to develop improved banana varieties. The first gene-edited non-browning banana has been deregulated in the Philippines recently, and more regulatory applications are expected to submit for approvals soon. Hence, it is timely to review the policy options for gene editing that have been adopted and discussed in the Southeast Asian countries and highlight the implications of differing regulatory approaches to gene editing for trading activities. Positive stakeholders' perceptions and public acceptance are key factors in allowing the benefits of gene editing and thus appropriate outreach strategies are important to gain acceptance and avoid the "GMO stigma" that may be associated with gene-edited products.
Language	English
Publishing date	2024-04-10
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	31620-9
ISSN	1573-9368 ; 0962-8819
ISSN (online)	1573-9368
ISSN	0962-8819
DOI	10.1007/s11248-024-00379-9
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Article ; Online: Numerical analysis of slip-enhanced flow over a curved surface with magnetized water-based hybrid nanofluid containing gyrotactic microorganisms.

Yasmin, Humaira / Lone, Showkat Ahmad / Tassaddiq, Asifa / Raizah, Zehba / Alrabaiah, Hussam / Saeed, Anwar

Scientific reports

2023 Volume 13, Issue 1, Page(s) 18816

Abstract: This article presents the two-dimensional flow of hybrid nanofluid comprising of gyrotactic microorganisms under the consequences of multiple slip conditions, magnetic field and thermal radiation across an elongating curved surface using porous media. ... ...

Abstract	This article presents the two-dimensional flow of hybrid nanofluid comprising of gyrotactic microorganisms under the consequences of multiple slip conditions, magnetic field and thermal radiation across an elongating curved surface using porous media. The nanoparticles of TiO
Language	English
Publishing date	2023-11-01
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-023-46214-9
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Article: A study of survival strategies for improving acclimatization of lowlanders at high-altitude.

Sharma, Poornima / Mohanty, Swaraj / Ahmad, Yasmin

Heliyon

2023 Volume 9, Issue 4, Page(s) e14929

Abstract: Human Acclimatization and therapeutic approaches are the core components for conquering the physiological variations at high altitude (≥2500 m) exposure. The declined atmospheric pressure and reduced partial pressure of oxygen at high altitudes tend to ... ...

Abstract	Human Acclimatization and therapeutic approaches are the core components for conquering the physiological variations at high altitude (≥2500 m) exposure. The declined atmospheric pressure and reduced partial pressure of oxygen at high altitudes tend to decrease the temperature by several folds. Hypobaric hypoxia is a major threat to humanity at high altitudes, and its potential effects include altitude mountain sickness. On severity, it may lead to the development of conditions like high-altitude cerebral edema (HACE) or high-altitude pulmonary edema (HAPE) and cause unexpected physiological changes in the healthy population of travelers, athletes, soldiers, and low landers while sojourning at high altitude. Previous investigations have been done on long-drawn-out acclimatization strategies such as the staging method to prevent the damage caused by high-altitude hypobaric Hypoxia. Inherent Limitations of this strategy hamper the daily lifestyle and time consuming for people. It is not suitable for the rapid mobilization of people at high altitudes. There is a need to recalibrate acclimatization strategies for improving health protection and adapting to the environmental variations at high altitudes. This narrative review details the geographical changes and physiological changes at high altitudes and presents a framework of acclimatization, pre-acclimatization, and pharmacological aspects of high-altitude survival to enhance the government efficacy and capacity for the strategic planning of acclimatization, use of therapeutics, and safe de-induction from high altitude for minimizing the life loss. It's simply too ambitious for the importance of the present review to reduce life loss, and it can be proved as the most essential aspect of the preparatory phase of high-altitude acclimatization in plateau regions without hampering the daily lifestyle. The application of pre-acclimatization techniques can be a boon for people serving at high altitudes, and it can be a short bridge for the rapid translocation of people at high altitudes by minimizing the acclimatization time.
Language	English
Publishing date	2023-03-28
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2023.e14929
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Article ; Online: A study of survival strategies for improving acclimatization of lowlanders at high-altitude

Poornima Sharma / Swaraj Mohanty / Yasmin Ahmad

Heliyon, Vol 9, Iss 4, Pp e14929- (2023)

2023

Abstract	Human Acclimatization and therapeutic approaches are the core components for conquering the physiological variations at high altitude (≥2500 m) exposure. The declined atmospheric pressure and reduced partial pressure of oxygen at high altitudes tend to decrease the temperature by several folds. Hypobaric hypoxia is a major threat to humanity at high altitudes, and its potential effects include altitude mountain sickness. On severity, it may lead to the development of conditions like high-altitude cerebral edema (HACE) or high-altitude pulmonary edema (HAPE) and cause unexpected physiological changes in the healthy population of travelers, athletes, soldiers, and low landers while sojourning at high altitude. Previous investigations have been done on long-drawn-out acclimatization strategies such as the staging method to prevent the damage caused by high-altitude hypobaric Hypoxia. Inherent Limitations of this strategy hamper the daily lifestyle and time consuming for people. It is not suitable for the rapid mobilization of people at high altitudes. There is a need to recalibrate acclimatization strategies for improving health protection and adapting to the environmental variations at high altitudes. This narrative review details the geographical changes and physiological changes at high altitudes and presents a framework of acclimatization, pre-acclimatization, and pharmacological aspects of high-altitude survival to enhance the government efficacy and capacity for the strategic planning of acclimatization, use of therapeutics, and safe de-induction from high altitude for minimizing the life loss. It's simply too ambitious for the importance of the present review to reduce life loss, and it can be proved as the most essential aspect of the preparatory phase of high-altitude acclimatization in plateau regions without hampering the daily lifestyle. The application of pre-acclimatization techniques can be a boon for people serving at high altitudes, and it can be a short bridge for the rapid translocation of people ...
Keywords	High altitude ; Hypobaric hypoxia ; Acclimatization ; Pre-acclimatization ; Intermittent hypoxia ; Science (General) ; Q1-390 ; Social sciences (General) ; H1-99
Subject code	580
Language	English
Publishing date	2023-04-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Draft Genome Sequence of

Ashraf, Neelma / Anwar, Munir Ahmad / Akhtar, Kalsoom / Yasmin, Sumera / Khaliq, Shazia

Microbiology resource announcements

2022 Volume 11, Issue 9, Page(s) e0072522

Abstract: We present the genome sequence ... ...

Abstract	We present the genome sequence of
Language	English
Publishing date	2022-08-16
Publishing country	United States
Document type	Journal Article
ISSN	2576-098X
ISSN (online)	2576-098X
DOI	10.1128/mra.00725-22
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Article ; Online: Molecular Profiling, Characterization and Antimicrobial Efficacy of Silver Nanoparticles Synthesized from

Khan, Sayab / Fiaz, Muhammad / Yasmin, Humaira / Ahmad, Junaid / Ullah, Amin / Niaz, Zeeshan / Hayat, Shubana / Ahmad, Ajaz / Kaushik, Prashant / Farid, Arshad

Molecules (Basel, Switzerland)

2023 Volume 28, Issue 17

Abstract: The use of natural products isolated from mushrooms against infection, cancer diseases and other oxidative-stress-related diseases is one of the cornerstones of modern medicine. Therefore, we tried to establish a combination of medicinal mushrooms and ... ...

Abstract	The use of natural products isolated from mushrooms against infection, cancer diseases and other oxidative-stress-related diseases is one of the cornerstones of modern medicine. Therefore, we tried to establish a combination of medicinal mushrooms and nanotechnology possibly with the field of medicine for the development of antibacterial agents against these MDR strains. The aim of the research was to understand the molecular identification, characterization and antibacterial action of
MeSH term(s)	Silver/pharmacology ; Metal Nanoparticles ; Phylogeny ; Anti-Infective Agents/pharmacology ; Agaricales ; Anti-Bacterial Agents/pharmacology ; Escherichia coli
Chemical Substances	Silver (3M4G523W1G) ; Anti-Infective Agents ; Anti-Bacterial Agents
Language	English
Publishing date	2023-08-28
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	1413402-0
ISSN	1420-3049 ; 1431-5165 ; 1420-3049
ISSN (online)	1420-3049
ISSN	1431-5165 ; 1420-3049
DOI	10.3390/molecules28176291
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Article ; Online: Computational investigation of pyrazinamide drugs and its transition metal complexes using a DFT approach.

Khan, Muhammad Sanwal / Maha, Nasir / Riaz, Maira / Yasmin, Tahira / Irfan, Ahmad / Basra, Muhammad Asim Raza

Journal of computational chemistry

2023 Volume 45, Issue 10, Page(s) 622–632

Abstract: Pyrazinamide, an antituberculosis but documented toxic drug, is subjected to computational investigation along with the metal complexes via a DFT approach to predict the structure-activity and structure-toxicity relationship. 6-31G(d,p) basis set was ... ...

Abstract	Pyrazinamide, an antituberculosis but documented toxic drug, is subjected to computational investigation along with the metal complexes via a DFT approach to predict the structure-activity and structure-toxicity relationship. 6-31G(d,p) basis set was used for Zn, Ni, Mn, Fe, and Co, while the SDD basis set was applied to Cu, Cr, Cd, and Hg. Several reactivity parameters and charge distribution were calculated and the reactivity profile was estimated. The complexes were found to be soft and polarizable which could be responsible for their binding with bacterial targets to inhibit their growth. In contrast, pyrazinamide which is found to be hard among all is susceptible to being toxic. Moreover, the electronegative nature of the complexes can endow them with a better antibacterial effect. Since metal complexes have been found to be less toxic and more biologically interactive by computational methods, they can be employed as potent drugs for the cure of tuberculosis.
MeSH term(s)	Pyrazinamide/pharmacology ; Coordination Complexes/pharmacology ; Mercury ; Anti-Bacterial Agents
Chemical Substances	Pyrazinamide (2KNI5N06TI) ; Coordination Complexes ; Mercury (FXS1BY2PGL) ; Anti-Bacterial Agents
Language	English
Publishing date	2023-12-08
Publishing country	United States
Document type	Journal Article
ZDB-ID	1479181-X
ISSN	1096-987X ; 0192-8651
ISSN (online)	1096-987X
ISSN	0192-8651
DOI	10.1002/jcc.27273
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Article ; Online: Compositional profiling and bioefficacy studies of pulses-supplemented isocaloric designer biscuits for recently diagnosed diabetic individuals.

Iahtisham-Ul-Haq / Akram, Aqsa / Yasmin, Iqra / Sharif, Hafiz Rizwan / Nayik, Gulzar Ahmad / Ramniwas, Seema / Siddiqui, Shahida Anusha

Food chemistry: X

2024 Volume 22, Page(s) 101305

Abstract: This study addresses global concerns about diabetes mellitus by exploring a novel approach to manage hyperglycemia through pulses-supplemented designer biscuits. Control and designer biscuits were prepared with varying proportions of wheat flour and ... ...

Abstract	This study addresses global concerns about diabetes mellitus by exploring a novel approach to manage hyperglycemia through pulses-supplemented designer biscuits. Control and designer biscuits were prepared with varying proportions of wheat flour and pulses (chickpea, mungbean). The pulses-supplemented biscuits exhibited increased protein content and reduced readily available carbohydrates. Selected designer biscuits, with 12.5 % incorporation of chickpea and mungbean pulse flour, demonstrated significantly lower glycemic index (69.17 ± 5.01) and higher satiety index (122.19 ± 8.85) compared to control biscuits. These showed 13 % less glycemic index and 9 % higher satiety index as compared to control biscuits. A four-week bio-efficacy trial involving diabetic subjects consuming these biscuits as a routine snack resulted in an 11.45 % decrease in fasting blood glucose and a 19.15 % reduction in random blood glucose levels. Insulin and HDL levels also significantly improved. The study concludes that these designer biscuits possess a hypoglycemic effect, offering a potential dietary intervention for managing diabetes.
Language	English
Publishing date	2024-03-19
Publishing country	Netherlands
Document type	Journal Article
ISSN	2590-1575
ISSN (online)	2590-1575
DOI	10.1016/j.fochx.2024.101305
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