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  1. Article: Perception and Recognition of Clinical Medical Physicist Roles and Responsibilities by Specialist Physician Staff: The First Mexican Survey.

    Bojórquez, Mariana Hernández / Rendón, Xóchitl López / Rojas-López, José Alejandro

    Journal of medical physics

    2023  Volume 48, Issue 4, Page(s) 328–332

    Abstract: Introduction: Although medical physics as a profession is recognized as part of the health-care professional workforce by the International Labor Organization, in the Mexican context, the figure of the medical physicist (MP) is often inappropriately ... ...

    Abstract Introduction: Although medical physics as a profession is recognized as part of the health-care professional workforce by the International Labor Organization, in the Mexican context, the figure of the medical physicist (MP) is often inappropriately associated solely with technical work, leading to perception, recognition, and salary implications. The aim of this study was to explore the perception of medical specialists regarding the role and responsibilities of MPs in clinical practice in Mexico.
    Methods: A national survey was answered by medical personnel, ranging from residents to qualified specialists in November 2019. The questionnaire consisted of ten questions related to perception of MPs. The survey was open to all medical specialists regardless of their involvement in the use of ionizing radiations or otherwise.
    Results: It was shown that approximately two-thirds of specialists know and recognize the medical physics profession in hospitals and the roles and responsibilities of MPs. However, 19% of medical specialists considered the standard of service as inadequate.
    Conclusion: MPs must exert greater efforts to promote their status and enhance the recognition of their contribution to health care. The low level of recognition in diagnostic and interventional radiology and in nuclear medicine in Mexico might be related to nonexistent or unclear documentation and inadequate regulations, policies, or directives promoted by the health-care authorities.
    Language English
    Publishing date 2023-12-05
    Publishing country India
    Document type Journal Article
    ZDB-ID 1193902-3
    ISSN 1998-3913 ; 0971-6203
    ISSN (online) 1998-3913
    ISSN 0971-6203
    DOI 10.4103/jmp.jmp_81_23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Updates in the diagnosis and management of small-bowel Crohn's disease.

    Carretero, Cristina / Bojorquez, Alejandro / Eliakim, Rami / Lazaridis, Nikolaos

    Best practice & research. Clinical gastroenterology

    2023  Volume 64-65, Page(s) 101855

    MeSH term(s) Humans ; Crohn Disease/diagnosis ; Crohn Disease/therapy ; Intestine, Small/diagnostic imaging
    Language English
    Publishing date 2023-08-09
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 2048181-0
    ISSN 1532-1916 ; 1521-6918
    ISSN (online) 1532-1916
    ISSN 1521-6918
    DOI 10.1016/j.bpg.2023.101855
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Efficient Protein Extraction Protocols for NanoLC-MS/MS Proteomics Analysis of Plant Tissues with High Proteolytic Activity: A Case Study with Pineapple Pulp.

    Bojórquez-Velázquez, Esaú / Elizalde-Contreras, José M / Zamora-Briseño, Jesús Alejandro / Ruiz-May, Eliel

    Methods in molecular biology (Clifton, N.J.)

    2022  Volume 2512, Page(s) 281–290

    Abstract: Proteomics is an essential tool to uncover the regulatory processes of fruit biology. In fruits with high proteolytic activity, the inhibition of endogenous proteases is key for successful protein extraction. In this chapter, we describe an efficient ... ...

    Abstract Proteomics is an essential tool to uncover the regulatory processes of fruit biology. In fruits with high proteolytic activity, the inhibition of endogenous proteases is key for successful protein extraction. In this chapter, we describe an efficient protocol for total protein extraction to deal with this inconvenience using pineapple pulp as an example. We corroborated the efficacy of our protein extraction protocols by carrying out nano LC-MS/MS analyses using a highly sensitive hybrid mass spectrometer. In doing so, we were able to identify over 3000 proteins in pineapple pulp. Our contribution paves the way for massive comparative proteomics scrutiny in pineapple fruits, as well as others plant tissues with high protease activity such as papaya, fig, and kiwi fruits.
    MeSH term(s) Ananas ; Fruit/metabolism ; Peptide Hydrolases ; Plant Proteins/metabolism ; Proteomics/methods ; Tandem Mass Spectrometry
    Chemical Substances Plant Proteins ; Peptide Hydrolases (EC 3.4.-)
    Language English
    Publishing date 2022-07-11
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1940-6029
    ISSN (online) 1940-6029
    DOI 10.1007/978-1-0716-2429-6_17
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  4. Article ; Online: Use of a plastic banded bag over the control body of the endoscope as a splash guard to minimize the biological hazard during the COVID-19 outbreak.

    Bojórquez, Alejandro / Súbtil, Jose Carlos / Betés, Maria Teresa / Muñoz-Navas, Miguel

    Endoscopy

    2020  Volume 52, Issue 9, Page(s) 818

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections ; Endoscopes ; Endoscopy, Gastrointestinal ; Humans ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-08-26
    Publishing country Germany
    Document type Journal Article ; Comment
    ZDB-ID 80120-3
    ISSN 1438-8812 ; 0013-726X
    ISSN (online) 1438-8812
    ISSN 0013-726X
    DOI 10.1055/a-1167-2751
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Fear of COVID-19 scale: validation in Spanish in the Mexican general population.

    Soto-Briseño, Alejandro I / Gómez-Díaz, Rita A / Valdez-González, Adriana L / Saldaña-Espinoza, Ricardo C / Bojórquez, José J Favila / Wacher, Niels H

    Gaceta medica de Mexico

    2022  Volume 157, Issue 6, Page(s) 566–573

    Abstract: Introduction: The fear of COVID-19 scale (FCV-19S) is used to screen for symptoms of anxiety and depression related to COVID-19 in the general population; it consists of seven questions with Likert-type answers (1-5). Our objective was to validate FCV- ... ...

    Title translation Escala de temor a la COVID- 19: validación de la versión en español en la población mexicana.
    Abstract Introduction: The fear of COVID-19 scale (FCV-19S) is used to screen for symptoms of anxiety and depression related to COVID-19 in the general population; it consists of seven questions with Likert-type answers (1-5). Our objective was to validate FCV-19S Spanish version in the Mexican general population.
    Material and methods: Analytical, cross-sectional design. Three-hundred and six subjects from the general population were included during 2020 after having signed informed consent. Barlett and Kaiser-Meyer-Olkin (KMO) sphericity tests were applied. Reliability was calculated with Cronbach's alpha, and external validity, using the Hospital Anxiety and Depression Scale and Pearson's correlation coefficient for retest.
    Results: The general population sample included 306 participants; 64.4 % were women (n = 197), mean age was 32 years (18-68). We obtained a KMO = 0.848, internal consistency with Cronbach's alpha = 0.870 (95% CI: 0.848-0.891), a rho coefficient of 0.508 (p < 0.001) and external validity of 0.151 (p = 0.008). Confirmatory analysis showed: χ
    Conclusions: According to our findings, the scale shows adequate psychometric properties: reliability, internal consistency, correlation with subsequent measurements and convergence validity, for initial screening of the Mexican general population.
    MeSH term(s) Adult ; COVID-19 ; Cross-Sectional Studies ; Fear ; Female ; Humans ; Reproducibility of Results ; SARS-CoV-2 ; Surveys and Questionnaires
    Language English
    Publishing date 2022-01-12
    Publishing country Mexico
    Document type Journal Article
    ZDB-ID 425456-9
    ISSN 0016-3813
    ISSN 0016-3813
    DOI 10.24875/GMM.M21000618
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  6. Article ; Online: Proteome Landscape during Ripening of Solid Endosperm from Two Different Coconut Cultivars Reveals Contrasting Carbohydrate and Fatty Acid Metabolic Pathway Modulation.

    Félix, Jean Wildort / Granados-Alegría, María Inés / Gómez-Tah, Rufino / Tzec-Simá, Miguel / Ruíz-May, Eliel / Canto-Canché, Blondy / Zamora-Briseño, Jesús Alejandro / Bojórquez-Velázquez, Esaú / Oropeza-Salín, Carlos / Islas-Flores, Ignacio

    International journal of molecular sciences

    2023  Volume 24, Issue 13

    Abstract: ... Cocos ... ...

    Abstract Cocos nucifera
    MeSH term(s) Endosperm/metabolism ; Cocos/metabolism ; Fatty Acids/metabolism ; Proteome/metabolism ; Proteomics ; Carbohydrates ; Metabolic Networks and Pathways
    Chemical Substances Fatty Acids ; Proteome ; Carbohydrates
    Language English
    Publishing date 2023-06-21
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms241310431
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Mass Spectrometry Approaches for SARS-CoV-2 Detection: Harnessing for Application in Food and Environmental Samples.

    Bojórquez-Velázquez, Esaú / Llamas-García, Miriam Livier / Elizalde-Contreras, José M / Zamora-Briseño, Jesús Alejandro / Ruiz-May, Eliel

    Viruses

    2022  Volume 14, Issue 5

    Abstract: The public health crisis caused by the emergence of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in 2019 has drastically changed our lifestyle in virtually all contexts around the world. SARS-CoV-2 is mainly airborne, transmitted by ... ...

    Abstract The public health crisis caused by the emergence of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in 2019 has drastically changed our lifestyle in virtually all contexts around the world. SARS-CoV-2 is mainly airborne, transmitted by the salivary droplets produced when infected people cough or sneeze. In addition, diarrhea symptoms and the detection of SARS-CoV-2 in feces suggest a fecal-oral route of contagion. Currently, the high demand for SARS-CoV-2 diagnosis has surpassed the availability of PCR and immunodetection probes and has prompted the development of other diagnostic alternatives. In this context, mass spectrometry (MS) represents a mature, robust alternative platform for detection of SARS-CoV-2 and other human viruses. This possibility has raised great interest worldwide. Therefore, it is time for the global application of MS as a feasible option for detecting SARS-CoV-2, not only in human fluids, but also in other matrices such as foods and wastewater. This review covers the most relevant established methods for MS-based SARS-CoV-2 detection and discusses the future application of these tools in different matrices. Significance: The Coronavirus Disease 2019 (COVID-19) pandemic highlighted the pros and cons of currently available PCR and immunodetection tools. The great concern over the infective potential of SARS-CoV-2 viral particles that can persist for several hours on different surfaces under various conditions further evidenced the need for reliable alternatives and high-throughput methods to meet the needs for mass detection of SARS-CoV-2. In this context, MS-based proteomics emerging from fundamental studies in life science can offer a robust option for SARS-CoV-2 detection in human fluids and other matrices. In addition, the substantial efforts towards detecting SARS-CoV-2 in clinal samples, position MS to support the detection of this virus in different matrices such as the surfaces of the packing food process, frozen foods, and wastewaters. Proteomics and mass spectrometry are, therefore, well positioned to play a role in the epidemiological control of COVID-19 and other future diseases. We are currently witnessing the opportunity to generate technologies to overcome prolonged pandemics for the first time in human history.
    MeSH term(s) COVID-19/diagnosis ; COVID-19 Testing ; Humans ; Mass Spectrometry ; Polymerase Chain Reaction ; SARS-CoV-2/genetics
    Language English
    Publishing date 2022-04-22
    Publishing country Switzerland
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2516098-9
    ISSN 1999-4915 ; 1999-4915
    ISSN (online) 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v14050872
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  8. Article: Commercially available endoscopy facemasks to prevent aerosolizing spread of droplets during COVID-19 outbreak.

    Bojórquez, Alejandro / Larequi, Francisco Javier Zozaya / Betés, Maria Teresa / Súbtil, José Carlos / Muñoz-Navas, Miguel

    Endoscopy international open

    2020  Volume 8, Issue 6, Page(s) E815–E816

    Keywords covid19
    Language English
    Publishing date 2020-06-02
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2761052-4
    ISSN 2196-9736 ; 2364-3722
    ISSN (online) 2196-9736
    ISSN 2364-3722
    DOI 10.1055/a-1180-8355
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  9. Article ; Online: The biohabitus of scarcity: bio-social dispositions and the "obesity epidemic" in Mexico.

    Martínez, Alejandro / Anduro, Iván / Bojorquez, Ietza

    Sociology of health & illness

    2020  Volume 42, Issue 5, Page(s) 1095–1107

    Abstract: In this article, we explore the potential of Warin et al.'s concept of biohabitus (a set of embodied biological and social dispositions) as a conceptual tool for the understanding of mechanisms behind the "obesity epidemic." Elaborating on this concept, ... ...

    Abstract In this article, we explore the potential of Warin et al.'s concept of biohabitus (a set of embodied biological and social dispositions) as a conceptual tool for the understanding of mechanisms behind the "obesity epidemic." Elaborating on this concept, we argue that a context of food scarcity gives rise to a biohabitus geared to energy-saving, expressed in both biological (the thrifty genotype/phenotype hypotheses) and symbolic dispositions (Bourdieu's "taste of necessity"), and the interaction between this type of biohabitus and changes in the food-related environment results in increased body mass index. We exemplify the use of this framework by applying it to the case of Mexico, a middle-income Latin American country with one of the highest prevalences of obesity worldwide. The example shows how the concept of biohabitus can help researchers move beyond disciplinary explanations, towards a more complex understanding of the conjunction of social and biological processes that result in differential patterns of health and disease.
    MeSH term(s) Body Mass Index ; Epidemics ; Food ; Humans ; Mexico/epidemiology ; Obesity/epidemiology
    Language English
    Publishing date 2020-03-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 795552-2
    ISSN 1467-9566 ; 0141-9889
    ISSN (online) 1467-9566
    ISSN 0141-9889
    DOI 10.1111/1467-9566.13080
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  10. Article ; Online: Comparing and integrating TMT-SPS-MS3 and label-free quantitative approaches for proteomics scrutiny in recalcitrant Mango (Mangifera indica L.) peel tissue during postharvest period.

    Bautista-Valle, Mirna V / Camacho-Vazquez, Carolina / Elizalde-Contreras, José M / Monribot-Villanueva, Juan Luis / Limón, Abraham M Vidal / Bojórquez-Velázquez, Esaú / Zamora-Briseño, Jesús Alejandro / Jorrin-Novo, Jesús V / Ruiz-May, Eliel

    Proteomics

    2023  Volume 24, Issue 5, Page(s) e2300239

    Abstract: Despite substantial advances in the use of proteomic technologies, their widespread application in fruit tissues of non-model and recalcitrant species remains limited. This hampers the understanding of critical molecular events during the postharvest ... ...

    Abstract Despite substantial advances in the use of proteomic technologies, their widespread application in fruit tissues of non-model and recalcitrant species remains limited. This hampers the understanding of critical molecular events during the postharvest period of fleshy tropical fruits. Therefore, we evaluated label-free quantitation (LFQ) and TMT-SPS-MS3 (TMT) approaches to analyse changes in the protein profile of mango peels during postharvest period. We compared two extraction methods (phenol and chloroform/methanol) and two peptide fractionation schemes (SCX and HPRP). We accurately identified 3065 proteins, of which, 1492 were differentially accumulated over at 6 days after harvesting (DAH). Both LFQ and TMT approaches share 210 differential proteins including cell wall proteins associated with fruit softening, as well as aroma and flavour-related proteins, which were increased during postharvest period. The phenolic protein extraction and the high-pH reverse-phase peptide fractionation was the most effective pipeline for relative quantification. Nevertheless, the information provided by the other tested strategies was significantly complementary. Besides, LFQ spectra allowed us to track down intact N-glycopeptides corroborating N-glycosylations on the surface of a desiccation-related protein. This work represents the largest proteomic comparison of mango peels during postharvest period made so far, shedding light on the molecular foundation of edible fruit during ripening.
    MeSH term(s) Mangifera/chemistry ; Mangifera/metabolism ; Proteomics ; Fruit/metabolism ; Phenols/analysis ; Phenols/metabolism ; Peptides/analysis
    Chemical Substances Phenols ; Peptides
    Language English
    Publishing date 2023-09-08
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2032093-0
    ISSN 1615-9861 ; 1615-9853
    ISSN (online) 1615-9861
    ISSN 1615-9853
    DOI 10.1002/pmic.202300239
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