Article ; Online: Preoperative T staging of urinary bladder cancer: efficacy of stalk detection and diagnostic performance of diffusion-weighted imaging at 3T.
2014 Volume 13, Issue 3, Page(s) 175–181
Abstract: Purpose: We evaluated the ability of diffusion-weighted imaging (DWI) at 3 tesla for diagnosing T ... a 3T MR scanner. Two radiologists interpreted T2WI plus DWI and T2WI for diagnosis of T stage and ... Conclusion: DWI at 3T was superior to T2WI for evaluating the T stage of bladder cancer, particularly ...
| Abstract | Purpose: We evaluated the ability of diffusion-weighted imaging (DWI) at 3 tesla for diagnosing T stage and detecting stalks in bladder cancer. Methods: In total, 39 consecutive patients with bladder tumors underwent magnetic resonance (MR) imaging that included T2-weighted imaging (T2WI) and DWI using a 3T MR scanner. Two radiologists interpreted T2WI plus DWI and T2WI for diagnosis of T stage and for detection of stalks. We used McNemar's test to examine differences in diagnostic performance and Fisher's exact test to evaluate differences in stalk detection frequency. Results: Specificity and accuracy in differentiating T1 tumors from T2 to T4 tumors were significantly better with T2WI plus DWI (83% [20/24] and 85% [33/39]) than T2WI (50% [12/24] and 67% [26/39]; P = 0.02), and accuracy for diagnosing tumor stage was significantly better with T2WI plus DWI (82% [32/39]) than T2WI alone (59% [23/39]; P = 0.03). The observers identified stalks in 11 tumors by T2WI (48% [11/23]) and 17 by DWI (74% [17/23]) (P < 0.03). Conclusion: DWI at 3T was superior to T2WI for evaluating the T stage of bladder cancer, particularly in differentiating T1 tumors from those T2 or higher, and in detecting stalks of papillary bladder tumors. |
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| MeSH term(s) | Adult ; Aged ; Aged, 80 and over ; Diagnosis, Differential ; Diffusion Magnetic Resonance Imaging/methods ; Female ; Humans ; Image Interpretation, Computer-Assisted/methods ; Image Processing, Computer-Assisted/methods ; Male ; Middle Aged ; Neoplasm Grading ; Observer Variation ; Preoperative Care/methods ; Reproducibility of Results ; Sensitivity and Specificity ; Urinary Bladder/pathology ; Urinary Bladder Neoplasms/pathology |
| Language | English |
| Publishing date | 2014-07-02 |
| Publishing country | Japan |
| Document type | Journal Article |
| ZDB-ID | 2217833-8 |
| ISSN | 1880-2206 ; 1347-3182 |
| ISSN (online) | 1880-2206 |
| ISSN | 1347-3182 |
| DOI | 10.2463/mrms.2013-0104 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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