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  1. Article ; Online: A microwave-assisted extraction method combined with magnetic ionic liquid-based dispersive liquid-liquid microextraction for the extraction of chloramine-T from fish samples prior to its determination by high-performance liquid chromatography.

    Alizadeh Panahi, Arshia / Javadi, Afshin / Afshar Mogaddam, Mohammad Reza

    Journal of separation science

    2023  Volume 46, Issue 10, Page(s) e2200893

    Abstract: In the present work, a combination of microwave-assisted extraction with magnetic ionic liquid-based dispersive liquid-liquid microextraction was developed for the extraction of chloramine-T from fish samples. In this method, the sample was mixed with a ... ...

    Abstract In the present work, a combination of microwave-assisted extraction with magnetic ionic liquid-based dispersive liquid-liquid microextraction was developed for the extraction of chloramine-T from fish samples. In this method, the sample was mixed with a hydrochloric acid solution and exposed to microwave irradiations. By doing so, chloramine-T was converted to p-toluenesulfonamide and extracted from the sample into an aqueous phase. Then, a mixture of acetonitrile (as a dispersive solvent) and magnetic ionic liquid (as an extraction solvent) was rapidly injected into the obtained solution. In the following, the magnetic solvent droplets including the extracted analytes were isolated from the aqueous solution in the presence of an external magnetic field and after diluting with acetonitrile injected into high-performance liquid chromatography equipped with a diode array detector. Under the optimum extraction conditions, high extraction recovery (78%), low limits of detection (7.2 ng/g) and quantification (23.9 ng/g), good repeatability (relative standard deviations ≤5.8 and 6.8% for intra- and inter-day precisions, respectively), and wide linear range (23.9-1000 ng/g) were obtained. Finally, various fish samples marketed in Tabriz city (East Azarbaijan, Iran) were analyzed with the suggested method.
    MeSH term(s) Animals ; Chromatography, High Pressure Liquid ; Ionic Liquids ; Liquid Phase Microextraction ; Microwaves ; Acetonitriles ; Fishes ; Ions ; Solvents
    Chemical Substances chloramine-T ; Ionic Liquids ; acetonitrile (Z072SB282N) ; Acetonitriles ; Ions ; Solvents
    Language English
    Publishing date 2023-03-17
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2047990-6
    ISSN 1615-9314 ; 1615-9306
    ISSN (online) 1615-9314
    ISSN 1615-9306
    DOI 10.1002/jssc.202200893
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  2. Article ; Online: Novelty in improvement of CAR T cell-based immunotherapy with the aid of CRISPR system.

    Hajifathali, Abbas / Lasemi, Maryam Vahdat / Mehravar, Maryam / Moshari, Mohammad Reza / Alizadeh, Afshin Mohammad / Roshandel, Elham

    Hematology, transfusion and cell therapy

    2023  Volume 46, Issue 1, Page(s) 58–66

    Abstract: Introduction: Chimeric Antigen Receptor (CAR) T cells have tremendous potentials for cancer treatment; however, various challenges impede their universal use. These restrictions include the poor function of T cells in tumor microenvironments, the ... ...

    Abstract Introduction: Chimeric Antigen Receptor (CAR) T cells have tremendous potentials for cancer treatment; however, various challenges impede their universal use. These restrictions include the poor function of T cells in tumor microenvironments, the shortage of tumor-specific antigens and, finally, the high cost and time-consuming process, as well as the poor scalability of the method. Creative gene-editing tools have addressed each of these limitations and introduced next generation products for cell therapy. The clustered regularly interspaced short palindromic repeats-associated endonuclease 9 (CRISPR/Cas9) system has triggered a revolution in biology fields, as it has a great capacity for genetic manipulation.
    Method: In this review, we considered the latest development of CRISPR/Cas9 methods for the chimeric antigen receptor T cell (CAR T)-based immunotherapy.
    Results: The ability of the CRISPR/Cas9 system to generate the universal CAR T cells and also potent T cells that are persistent against exhaustion and inhibition was explored.
    Conclusion: We explained CRISPR delivery methods, as well as addressing safety concerns related to the use of the CRISPR/Cas9 system and their potential solutions.
    Language English
    Publishing date 2023-07-12
    Publishing country Brazil
    Document type Journal Article ; Review
    ISSN 2531-1387
    ISSN (online) 2531-1387
    DOI 10.1016/j.htct.2023.05.009
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  3. Article ; Online: A microwave‐assisted extraction method combined with magnetic ionic liquid‐based dispersive liquid–liquid microextraction for the extraction of chloramine–T from fish samples prior to its determination by high‐performance liquid chromatography

    Alizadeh Panahi, Arshia / Javadi, Afshin / Afshar Mogaddam, Mohammad Reza

    Journal of Separation Science. 2023 May, v. 46, no. 10 p.e2200893-

    2023  

    Abstract: In the present work, a combination of microwave‐assisted extraction with magnetic ionic liquid–based dispersive liquid–liquid microextraction was developed for the extraction of chloramine–T from fish samples. In this method, the sample was mixed with a ... ...

    Abstract In the present work, a combination of microwave‐assisted extraction with magnetic ionic liquid–based dispersive liquid–liquid microextraction was developed for the extraction of chloramine–T from fish samples. In this method, the sample was mixed with a hydrochloric acid solution and exposed to microwave irradiations. By doing so, chloramine–T was converted to p–toluenesulfonamide and extracted from the sample into an aqueous phase. Then, a mixture of acetonitrile (as a dispersive solvent) and magnetic ionic liquid (as an extraction solvent) was rapidly injected into the obtained solution. In the following, the magnetic solvent droplets including the extracted analytes were isolated from the aqueous solution in the presence of an external magnetic field and after diluting with acetonitrile injected into high‐performance liquid chromatography equipped with a diode array detector. Under the optimum extraction conditions, high extraction recovery (78%), low limits of detection (7.2 ng/g) and quantification (23.9 ng/g), good repeatability (relative standard deviations ≤5.8 and 6.8% for intra– and inter‐day precisions, respectively), and wide linear range (23.9–1000 ng/g) were obtained. Finally, various fish samples marketed in Tabriz city (East Azarbaijan, Iran) were analyzed with the suggested method.
    Keywords acetonitrile ; aqueous solutions ; chemical species ; diodes ; fish ; high performance liquid chromatography ; hydrochloric acid ; ionic liquids ; liquid-phase microextraction ; magnetic fields ; microwave treatment ; separation ; Iran
    Language English
    Dates of publication 2023-05
    Publishing place John Wiley & Sons, Ltd
    Document type Article ; Online
    Note JOURNAL ARTICLE
    ZDB-ID 2047990-6
    ISSN 1615-9314 ; 1615-9306
    ISSN (online) 1615-9314
    ISSN 1615-9306
    DOI 10.1002/jssc.202200893
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  4. Article ; Online: Cell-Based Therapy Approaches in Treatment of Non-obstructive Azoospermia.

    Roshandel, Elham / Mehravar, Maryam / Nikoonezhad, Maryam / Alizadeh, Afshin Mohammad / Majidi, Mohammad / Salimi, Maryam / Hajifathali, Abbas

    Reproductive sciences (Thousand Oaks, Calif.)

    2022  Volume 30, Issue 5, Page(s) 1482–1494

    Abstract: The rate of infertility has globally increased in recent years for a variety of reasons. One of the main causes of infertility in men is azoospermia that is defined by the absence of sperm in the ejaculate and classified into two categories: obstructive ... ...

    Abstract The rate of infertility has globally increased in recent years for a variety of reasons. One of the main causes of infertility in men is azoospermia that is defined by the absence of sperm in the ejaculate and classified into two categories: obstructive azoospermia and non-obstructive azoospermia. In non-obstructive azoospermia, genital ducts are not obstructed, but the testicles do not produce sperm at all, due to various reasons. Non-obstructive azoospermia in most cases has no therapeutic options other than assisted reproductive techniques, which in most cases require sperm donors. Here we discuss cell-based therapy approaches to restore fertility in men with non-obstructive azoospermia including cell-based therapies of non-obstructive azoospermia using regenerative medicine and cell-based therapies of non-obstructive azoospermia by paracrine and anti-inflammatory pathway, technical and ethical challenges for using different cell sources and alternative options will be described, and then the more effectual approaches will be mentioned as future trends.
    MeSH term(s) Humans ; Male ; Azoospermia/therapy ; Azoospermia/etiology ; Sperm Retrieval ; Semen ; Testis ; Reproductive Techniques, Assisted/adverse effects
    Language English
    Publishing date 2022-11-15
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2276411-2
    ISSN 1933-7205 ; 1933-7191
    ISSN (online) 1933-7205
    ISSN 1933-7191
    DOI 10.1007/s43032-022-01115-6
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  5. Article: Comparison of plasma zinc levels between patients undergoing liver transplantation and healthy subjects

    Nejatollahi, Seyed Mohammad Reza / Abbasinazari, Mohammad / Marashi, Seyed Ali / Janatmakan, Farahzad / Moshari, Mohammad Reza / Alizadeh, Afshin Mohammad / Fazel, Iradj

    Trace elements and electrolytes

    2020  Volume 37, Issue 3, Page(s) 108

    Language German
    Document type Article
    ZDB-ID 1181166-3
    ISSN 0946-2104
    Database Current Contents Medicine

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  6. Article ; Online: Treatment of foodborne botulism in current clinical toxicology.

    Alizadeh, Afshin Mohammad / Zamani, Nasim

    Pediatric reports

    2012  Volume 4, Issue 2, Page(s) e22

    Language English
    Publishing date 2012-06-11
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2572005-3
    ISSN 2036-7503 ; 2036-7503
    ISSN (online) 2036-7503
    ISSN 2036-7503
    DOI 10.4081/pr.2012.e22
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  7. Article ; Online: Myiasis in an 89-year-old man with non-hodgkin lymphoma.

    Afshin Mohammad Alizadeh / Nasim Zamani

    Iranian Journal of Arthropod-Borne Diseases , Vol 8, Iss 1, Pp 117-

    2014  Volume 8

    Abstract: Myiasis is due to the opportunistic dipterous larvae feeding on viable or necrotic tissues of the host occurring throughout the world. We report a case of oral myiasis in an immune-compromised patient suffering from non-Hodgkin lymphoma. We would like to ...

    Abstract Myiasis is due to the opportunistic dipterous larvae feeding on viable or necrotic tissues of the host occurring throughout the world. We report a case of oral myiasis in an immune-compromised patient suffering from non-Hodgkin lymphoma. We would like to emphasize that such ectoparasitic infections may happen in immunocompromised patients and oral hygiene should be evaluated in all of these patients.
    Keywords immune-compromised host ; lymphoma ; myiasis ; oral ; Medicine ; R ; Internal medicine ; RC31-1245 ; Specialties of internal medicine ; RC581-951 ; Immunologic diseases. Allergy ; RC581-607
    Language English
    Publishing date 2014-06-01T00:00:00Z
    Publisher Tehran University of Medical Sciences
    Document type Article ; Online
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  8. Article ; Online: Comment on "Applicability of different scoring systems in outcome prediction of patients with mixed drug poisoning-induced coma".

    Zamani, Nasim / Alizadeh, Afshin Mohammad

    Indian journal of anaesthesia

    2012  Volume 56, Issue 3, Page(s) 308

    Language English
    Publishing date 2012-04-20
    Publishing country India
    Document type Journal Article
    ZDB-ID 412570-8
    ISSN 0976-2817 ; 0019-5049
    ISSN (online) 0976-2817
    ISSN 0019-5049
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  9. Article: Myiasis in an 89-year-old man with non-hodgkin lymphoma.

    Alizadeh, Afshin Mohammad / Zamani, Nasim

    Journal of arthropod-borne diseases

    2013  Volume 8, Issue 1, Page(s) 117–118

    Abstract: Myiasis is due to the opportunistic dipterous larvae feeding on viable or necrotic tissues of the host occurring throughout the world. We report a case of oral myiasis in an immune-compromised patient suffering from non-Hodgkin lymphoma. We would like to ...

    Abstract Myiasis is due to the opportunistic dipterous larvae feeding on viable or necrotic tissues of the host occurring throughout the world. We report a case of oral myiasis in an immune-compromised patient suffering from non-Hodgkin lymphoma. We would like to emphasize that such ectoparasitic infections may happen in immunocompromised patients and oral hygiene should be evaluated in all of these patients.
    Language English
    Publishing date 2013-12-18
    Publishing country Iran
    Document type Case Reports
    ZDB-ID 2695958-6
    ISSN 2322-2271 ; 2322-1984
    ISSN (online) 2322-2271
    ISSN 2322-1984
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  10. Article ; Online: Drug-induced cholestatic hepatitis: how late can it occur even after the cessation of the culpable drug?

    Zamani, Nasim / Mohammad Alizadeh, Afshin

    Neuro-oncology

    2012  Volume 14, Issue 7, Page(s) 830

    MeSH term(s) Acetaminophen/adverse effects ; Analgesics, Non-Narcotic/adverse effects ; Antineoplastic Agents, Alkylating/adverse effects ; Chemical and Drug Induced Liver Injury/etiology ; Cholestasis/chemically induced ; Dacarbazine/adverse effects ; Dacarbazine/analogs & derivatives ; Drug Therapy, Combination ; Glioblastoma/drug therapy ; Humans ; Male ; Middle Aged ; Prognosis ; Temozolomide
    Chemical Substances Analgesics, Non-Narcotic ; Antineoplastic Agents, Alkylating ; Acetaminophen (362O9ITL9D) ; Dacarbazine (7GR28W0FJI) ; Temozolomide (YF1K15M17Y)
    Language English
    Publishing date 2012-04-26
    Publishing country England
    Document type Case Reports ; Letter
    ZDB-ID 2028601-6
    ISSN 1523-5866 ; 1522-8517
    ISSN (online) 1523-5866
    ISSN 1522-8517
    DOI 10.1093/neuonc/nos090
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