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  1. Article ; Online: On the 400th anniversary of the birth of Thomas Willis.

    Molnár, Zoltán

    Brain : a journal of neurology

    2021  Volume 144, Issue 4, Page(s) 1033–1037

    MeSH term(s) Anniversaries and Special Events ; History, 17th Century ; Humans ; Neuroanatomy/history
    Language English
    Publishing date 2021-01-29
    Publishing country England
    Document type Biography ; Historical Article ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 80072-7
    ISSN 1460-2156 ; 0006-8950
    ISSN (online) 1460-2156
    ISSN 0006-8950
    DOI 10.1093/brain/awab016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Development and Evolution of Thalamocortical Connectivity.

    Molnár, Zoltán / Kwan, Kenneth Y

    Cold Spring Harbor perspectives in biology

    2024  Volume 16, Issue 1

    Abstract: Conscious perception in mammals depends on precise circuit connectivity between cerebral cortex and thalamus; the evolution and development of these structures are closely linked. During the wiring of reciprocal thalamus-cortex connections, ... ...

    Abstract Conscious perception in mammals depends on precise circuit connectivity between cerebral cortex and thalamus; the evolution and development of these structures are closely linked. During the wiring of reciprocal thalamus-cortex connections, thalamocortical axons (TCAs) first navigate forebrain regions that had undergone substantial evolutionary modifications. In particular, the organization of the pallial-subpallial boundary (PSPB) diverged significantly between mammals, reptiles, and birds. In mammals, transient cell populations in internal capsule and early corticofugal projections from subplate neurons closely interact with TCAs to guide pathfinding through ventral forebrain and PSPB crossing. Prior to thalamocortical axon arrival, cortical areas are initially patterned by intrinsic genetic factors. Thalamocortical axons then innervate cortex in a topographically organized manner to enable sensory input to refine cortical arealization. Here, we review the mechanisms underlying the guidance of thalamocortical axons across forebrain boundaries, the implications of PSPB evolution for thalamocortical axon pathfinding, and the reciprocal influence between thalamus and cortex during development.
    MeSH term(s) Animals ; Thalamus ; Neurons ; Axons/physiology ; Cerebral Cortex ; Mammals ; Neural Pathways/physiology
    Language English
    Publishing date 2024-01-02
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 1943-0264
    ISSN (online) 1943-0264
    DOI 10.1101/cshperspect.a041503
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book: Gesund durch Schröpfen

    Frenkel, Wolf Gerhard / Molnar, U. Pecs Zoltan / Bamberger, Georg

    Grundlagen und Anwendung ; mit ... 13 Tabellen

    2014  

    Author's details Wolf Gerhard Frenkel ; U. Pecs Zoltan Molnar ; Georg Bamberger
    Keywords Complementary Therapies ; Schröpfkopftherapie
    Subject Schröpfen ; Schröpftherapie ; Hämospasie
    Language German
    Size XIV, 134 S. : zahlr. Ill., graph. Darst., 210 mm x 210 mm
    Edition 2., überarb. Aufl.
    Publisher Schattauer
    Publishing place Stuttgart u.a.
    Publishing country Germany
    Document type Book
    HBZ-ID HT018348117
    ISBN 978-3-7945-3085-4 ; 3-7945-3085-3
    Database Catalogue ZB MED Medicine, Health

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  4. Article: Possibilities and limits of modelling of long-range economic consequences of air pollution - A case study.

    Lakner, Zoltán / Popp, József / Oláh, Judit / Zéman, Zoltán / Molnár, Viktória

    Heliyon

    2024  Volume 10, Issue 4, Page(s) e26483

    Abstract: Air pollution is the biggest environmental problem in modern societies, causing considerable health damage and requiring substantial financial resources for health care. The goal of the study is to demonstrate the adverse economic consequences of air ... ...

    Abstract Air pollution is the biggest environmental problem in modern societies, causing considerable health damage and requiring substantial financial resources for health care. The goal of the study is to demonstrate the adverse economic consequences of air pollution on example of a small, open Central European country, Hungary, and to provide quantified financial arguments for macroeconomic decision-making for the development of a long-term energy strategy. On the basis of the Cobb-Douglas production function and Solow-Swann model of dynamic economic systems a simple and robust model was constructed to estimate and predict economic losses, caused by the pollution. On base of results it is obvious, that on base of macroeconomic theory and combination of various, publicly available, quality-controlled statistical resources quantifiable models can be constructed to characterise the economic consequences of air pollution, but it should be taken into consideration, that the reliability of economic models considerably depends on their initial parameters and practical validity of assumptions, based on which the underlying economic theories were built. The most important economic burden of air pollution is caused by the loss of working-age population, resulting in a decrease of 4.1-9.4 % a year in Gross Domestic Product (GDP) in the next fifty years. The additional burden of health care costs amounts to 0.1 % of GDP. Reducing air pollution is not only a quality of life improvement but also an investment into the economic development. Notwithstanding of statistical biases it could be proven the importance of combination health economic and econometric methods in preparation of more efficient environmental-related socio-economic decisions.
    Language English
    Publishing date 2024-02-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2024.e26483
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Book ; Conference proceedings: Evolution and development of nervous systems

    Molnár, Zoltán

    proceedings of the 4th European Conference on Comparative Neurobiology ; April 15 - 17, 2004, St. John's College, Oxford

    (Brain research bulletin ; 66,4/6 = Special issue)

    2005  

    Event/congress European Conference on Comparative Neurobiology (4, 2004, Oxford)
    Author's details guest ed.: Z. Molnár
    Series title Brain research bulletin ; 66,4/6 = Special issue
    Collection
    Language English
    Size VIII S., S. 269 - 564 : Ill., graph. Darst.
    Publisher Elsevier
    Publishing place New York, NY
    Publishing country United States
    Document type Book ; Conference proceedings
    HBZ-ID HT014750519
    Database Catalogue ZB MED Medicine, Health

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  6. Article ; Online: Cortical layer with no known function.

    Molnár, Zoltán

    The European journal of neuroscience

    2018  Volume 49, Issue 7, Page(s) 957–963

    MeSH term(s) Cerebral Cortex/cytology ; Cerebral Cortex/growth & development ; Cerebral Cortex/physiology ; History, 20th Century ; History, 21st Century ; Neural Pathways/cytology ; Neural Pathways/growth & development ; Neural Pathways/physiology ; Neurosciences/history ; Thalamus/cytology ; Thalamus/growth & development ; Thalamus/physiology
    Language English
    Publishing date 2018-08-03
    Publishing country France
    Document type Biography ; Editorial ; Historical Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 645180-9
    ISSN 1460-9568 ; 0953-816X
    ISSN (online) 1460-9568
    ISSN 0953-816X
    DOI 10.1111/ejn.13978
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Professor Sir Colin Blakemore FRS, a brilliant force for good within neuroscience and beyond (1944-2022).

    Molnár, Zoltán / Hannan, Anthony J

    Nature neuroscience

    2022  Volume 25, Issue 10, Page(s) 1249–1250

    MeSH term(s) History, 20th Century ; History, 21st Century ; Neurosciences/history
    Language English
    Publishing date 2022-08-02
    Publishing country United States
    Document type Biography ; Editorial ; Historical Article
    ZDB-ID 1420596-8
    ISSN 1546-1726 ; 1097-6256
    ISSN (online) 1546-1726
    ISSN 1097-6256
    DOI 10.1038/s41593-022-01139-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Book: Gesund durch Schröpfen

    Frenkel, Wolf Gerhard / Molnar, U. Pecs Zoltan / Bamberger, Georg

    Grundlagen und Anwendung ; mit ... 13 Tabellen

    2010  

    Author's details Wolf Gerhard Frenkel ; U. Pecs Zoltan Molnar ; Georg Bamberger
    Keywords Complementary Therapies ; Schröpfkopftherapie
    Subject Schröpfen ; Schröpftherapie ; Hämospasie
    Language German
    Size XIV, 130 S. : zahlr. Ill., graph. Darst., 210 mm x 210 mm
    Publisher Schattauer
    Publishing place Stuttgart u.a.
    Publishing country Germany
    Document type Book
    HBZ-ID HT016117536
    ISBN 978-3-7945-2759-5 ; 3-7945-2759-3
    Database Catalogue ZB MED Medicine, Health

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  9. Article ; Online: Sources of Variance in Human Tear Proteomic Samples: Statistical Evaluation, Quality Control, Normalization, and Biological Insight.

    Bruszel, Bella / Tóth-Molnár, Edit / Janáky, Tamás / Szabó, Zoltán

    International journal of molecular sciences

    2024  Volume 25, Issue 3

    Abstract: Human tear fluid contains numerous compounds, which are present in highly variable amounts owing to the dynamic and multipurpose functions of tears. A better understanding of the level and sources of variance is essential for determining the functions of ...

    Abstract Human tear fluid contains numerous compounds, which are present in highly variable amounts owing to the dynamic and multipurpose functions of tears. A better understanding of the level and sources of variance is essential for determining the functions of the different tear components and the limitations of tear samples as a potential biomarker source. In this study, a quantitative proteomic method was used to analyze variations in the tear protein profiles of healthy volunteers. High day-to-day and inter-eye personal variances were observed in the tear volumes, protein content, and composition of the tear samples. Several normalization and outlier exclusion approaches were evaluated to decrease variances. Despite the intrapersonal variances, statistically significant differences and cluster analysis revealed that proteome profile and immunoglobulin composition of tear fluid present personal characteristics. Using correlation analysis, we could identify several correlating protein clusters, mainly related to the source of the proteins. Our study is the first attempt to achieve more insight into the biochemical background of human tears by statistical evaluation of the experimentally observed dynamic behavior of the tear proteome. As a pilot study for determination of personal protein profiles of the tear fluids of individual patients, it contributes to the application of this noninvasively collectible body fluid in personal medicine.
    MeSH term(s) Humans ; Proteome/metabolism ; Proteomics/methods ; Pilot Projects ; Tears/metabolism ; Eye Proteins/metabolism ; Quality Control
    Chemical Substances Proteome ; Eye Proteins
    Language English
    Publishing date 2024-01-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms25031559
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: OCULAR NECESSITIES: A NEUROETHOLOGICAL PERSPECTIVE ON VERTEBRATE VISUAL DEVELOPMENT.

    Hunt, Jasper Elan / Pratt, Kara Geo / Molnar, Zoltán

    Brain, behavior and evolution

    2024  

    Abstract: Background: By examining species-specific innate behaviours, neuroethologists have characterised unique neural strategies and specializations from throughout the animal kingdom. Simultaneously, the field of evolutionary developmental biology (informally, ...

    Abstract Background: By examining species-specific innate behaviours, neuroethologists have characterised unique neural strategies and specializations from throughout the animal kingdom. Simultaneously, the field of evolutionary developmental biology (informally, "evo-devo") seeks to make inferences about animals' evolutionary histories through careful comparison of developmental processes between species, because evolution is the evolution of development. Yet despite the shared focus on cross-species comparisons, there is surprisingly little cross-talk between these two fields. Insights can be gleaned at the intersection of neuroethology and evo-devo. Every animal develops within an environment, wherein ecological pressures advantage some behaviours and disadvantage others. These pressures are reflected in the neurodevelopmental strategies employed by different animals across taxa.
    Summary: Vision is a system of particular interest for studying the adaptation of animals to their environments. The visual system enables a wide variety of animals across the vertebrate lineage to interact with their environments, presenting a fantastic opportunity to examine how ecological pressures have shaped animals' behaviours and developmental strategies. Applying a neuroethological lens to the study of visual development, we advance a novel theory that accounts for the evolution of spontaneous retinal waves, an important phenomenon in the development of the visual system, across the vertebrate lineage.
    Key messages: We synthesise literature on spontaneous retinal waves from across the vertebrate lineage. We find that ethological considerations explain some cross-species differences in the dynamics of retinal waves. In zebrafish, retinal waves may be more important for the development of the retina itself, rather than the retinofugal projections. We additionally suggest empirical tests to determine whether Xenopus laevis experiences retinal waves.
    Language English
    Publishing date 2024-03-06
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 1199-x
    ISSN 1421-9743 ; 0006-8977
    ISSN (online) 1421-9743
    ISSN 0006-8977
    DOI 10.1159/000536035
    Database MEDical Literature Analysis and Retrieval System OnLINE

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