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  1. Article ; Online: January consultation #2.

    Mosaed, Sameh

    Journal of cataract and refractive surgery

    2020  Volume 46, Issue 1, Page(s) 154–155

    MeSH term(s) Adult ; Female ; Glaucoma, Open-Angle/physiopathology ; Glaucoma, Open-Angle/surgery ; Humans ; Intraocular Pressure/physiology ; Trabeculectomy/methods
    Language English
    Publishing date 2020-06-08
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 632744-8
    ISSN 1873-4502 ; 0886-3350
    ISSN (online) 1873-4502
    ISSN 0886-3350
    DOI 10.1097/01.j.jcrs.0000668260.00212.05
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Ab interno trabeculotomy in uveitic glaucoma: Confirmation of original results with extended applications.

    Mosaed, Sameh

    Clinical & experimental ophthalmology

    2020  Volume 48, Issue 1, Page(s) 12–13

    MeSH term(s) Glaucoma/surgery ; Humans ; Trabeculectomy
    Language English
    Publishing date 2020-02-08
    Publishing country Australia
    Document type Editorial ; Comment
    ZDB-ID 2014008-3
    ISSN 1442-9071 ; 1442-6404
    ISSN (online) 1442-9071
    ISSN 1442-6404
    DOI 10.1111/ceo.13699
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Overlapping Spots of Photodynamic Therapy for Treatment of Choroidal Hemangioma in Sturge-Weber Syndrome: A Case Report.

    Pai, Alex Y / Han, Michael M / Mosaed, Sameh / Esfahani, Mohammad Riazi

    Case reports in ophthalmology

    2024  Volume 15, Issue 1, Page(s) 411–417

    Abstract: Introduction: Photodynamic therapy (PDT) has shown substantial benefit in the treatment of choroidal hemangioma (CH) in recent years. This report describes the use of PDT with overlapping spots in a patient with Sturge-Weber syndrome (SWS) and large ... ...

    Abstract Introduction: Photodynamic therapy (PDT) has shown substantial benefit in the treatment of choroidal hemangioma (CH) in recent years. This report describes the use of PDT with overlapping spots in a patient with Sturge-Weber syndrome (SWS) and large circumscribed CH.
    Case presentation: A 9-year-old girl with SWS and a history of glaucoma in her left eye was referred to a retina clinic for possible macular changes. Examination revealed decreased vision in the left eye, pigmentary changes in the macula, and choroidal thickening in the posterior pole. After being lost to follow-up for 2 years, the patient returned with further vision deterioration with best-corrected visual acuity (BCVA) of 20/150 and new subretinal fluid (SRF). Imaging findings were consistent with a diagnosis of CH and SRF. PDT with verteporfin was initiated on the entire area with multiple overlapping spots, resulting in resolution of SRF and improvement in visual acuity and choroidal contour. At 18-month post-treatment, the patient's BCVA was 20/25 with no recurrence of SRF or increased choroidal thickening. Significant pigmentary changes and subretinal hyper-reflective material were observed in the OCT of the treated area.
    Conclusion: Multiple overlapping laser spots of PDT can result in longstanding regression of large circumscribed CH in a patient with SWS with excellent final visual acuity. However, significant subretinal changes may also result following this method of treatment.
    Language English
    Publishing date 2024-04-30
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2577666-6
    ISSN 1663-2699
    ISSN 1663-2699
    DOI 10.1159/000535948
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Prospective Study of Canaloplasty and Trabeculotomy Performed by Trainees.

    Smith, Andrew K / Kwan, Changyow C / Fox, Austin / Noh, Stephanie / Gustafson, Kevin / Lin, Ken Y / Mosaed, Sameh

    Clinical ophthalmology (Auckland, N.Z.)

    2024  Volume 18, Page(s) 17–26

    Abstract: Purpose: To evaluate outcomes of new adopters of the OMNI: Patients and methods: This was a prospective study of surgeries performed by trainees on patients with open angle glaucoma undergoing simultaneous cataract surgery and ab interno canaloplasty ...

    Abstract Purpose: To evaluate outcomes of new adopters of the OMNI
    Patients and methods: This was a prospective study of surgeries performed by trainees on patients with open angle glaucoma undergoing simultaneous cataract surgery and ab interno canaloplasty and trabeculotomy using the OMNI Surgical System. Pre-operative intraocular pressure (IOP) and number of glaucoma medications were recorded. Only patients with a minimum of 6-month follow up were included. Baseline IOP was used to separate subjects into two groups: Group 1 (IOP ≥18 mmHg) and Group 2 (IOP <18 mmHg). Mean decrease in IOP and medications was calculated and compared with paired t-tests for the overall sample as well as the subgroups. Success was defined as those with a ≥20% reduction from pre-operative IOP or with an IOP ≤18 mmHg and ≥6 mmHg and on the same or fewer number of medications while not requiring additional surgery. Adverse events were also recorded.
    Results: Forty-two eyes of 31 patients were included. Mean pre-operative IOP was 17.2 ± 4.8 mmHg and mean number of medications was 2.4 ± 1.2. The primary endpoint was reached in 83.3% of patients at 12 months. IOP was reduced by 22.3% to 13.4 ± 2.4 (p<0.001). Mean number of medications decreased to 1.7 ± 1.6 (p<0.001). Group 1 mean IOP decreased 35.4% from 22.2 ± 4.6 mmHg to 14.3 ± 2.8 mmHg (p<0.001). Group 2 mean number of medications decreased from 2.3 ± 1.1 to 1.6 ± 1.5 (p<0.001).
    Conclusion: When operated on by the novice MIGS surgeon, the OMNI device provides effective IOP and glaucoma medication reduction with minimal adverse events. Efficacy and safety of the device in the hands of trainees was comparable to experienced glaucoma surgeons suggesting its ease of adoption.
    Language English
    Publishing date 2024-01-03
    Publishing country New Zealand
    Document type Journal Article
    ISSN 1177-5467
    ISSN 1177-5467
    DOI 10.2147/OPTH.S441834
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Ab Externo Imaging of Human Episcleral Vessels Using Fiberoptic Confocal Laser Endomicroscopy.

    Y Lin, Ken / Mosaed, Sameh

    Journal of ophthalmic & vision research

    2019  Volume 14, Issue 3, Page(s) 275–284

    Abstract: Purpose: There is a growing interest in targeting minimally invasive surgery devices to the aqueous outflow system to optimize treatment outcomes. However, methods to visualize functioning, large-caliber aqueous and episcleral veins : Methods: A ... ...

    Abstract Purpose: There is a growing interest in targeting minimally invasive surgery devices to the aqueous outflow system to optimize treatment outcomes. However, methods to visualize functioning, large-caliber aqueous and episcleral veins
    Methods: A fiber-optic confocal laser endomicroscopy (CLE) system with lateral and axial resolution of 3.5
    Results: Vascular structures were visualized in whole human eyes without processing. Schlemm's canal was visualized only after a scleral flap was created. Fluorescent signal intensity and vessel diameter variation were observed along the limbal circumference, with the inferior quadrant having a statistically higher fluorescein signal compared to the other quadrants in human eyes (
    Conclusion: This study demonstrates for the first time that the fiber-optic CLE platform can visualize the episcleral vasculature with high resolution
    Language English
    Publishing date 2019-07-18
    Publishing country United Arab Emirates
    Document type Journal Article ; Review
    ISSN 2008-2010
    ISSN 2008-2010
    DOI 10.18502/jovr.v14i3.4783
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Capnocytophaga canimorsus blebitis: case report and review of literature.

    Yang, Michael C / Ling, John / Mosaed, Sameh

    BMC ophthalmology

    2021  Volume 21, Issue 1, Page(s) 59

    Abstract: Background: Capnocytophaga canimorsus is a facultative anaerobic, slow-growing, capnophilic, Gram-negative bacillus, that is commonly found in the microflora of canine and feline oral cavities. Capnocytophaga infections are an emerging zoonotic disease ... ...

    Abstract Background: Capnocytophaga canimorsus is a facultative anaerobic, slow-growing, capnophilic, Gram-negative bacillus, that is commonly found in the microflora of canine and feline oral cavities. Capnocytophaga infections are an emerging zoonotic disease that can cause fatal systemic infections in immunocompromised individuals. Localized ocular Capnocytophaga infections, including keratitis, blepharitis, and endophthalmitis, can lead to severe eye threatening situations. To our knowledge, there is currently no documented case of Capnocytophaga canimorsus blebitis with bleb perforation after trabeculectomy.
    Case presentation: Our case report and literature review features a novel case of Capnocytophaga blebitis that occurred after trabeculectomy, associated with close dog contact (i.e. face licking). The patient had underwent trabeculectomy 10 years prior and presented with conjunctival injection, perforated bleb, and hypotony. Overall, patient was medically treated subconjunctival vancomycin, gentamicin and moxifloxacin drops. Trabeculectomy revision was performed with good visual outcome. Bacterial cultures grew Capnocytophaga canimorsus.
    Conclusions: We discuss the strategies for diagnosis, treatment, and common risk factors for ocular Capnocytophaga infections. At-risk patients with ocular infections should be asked about close contact with dogs and cats; and treated promptly with the proper antibiotic regimen.
    MeSH term(s) Animals ; Capnocytophaga ; Cat Diseases ; Cats ; Dog Diseases ; Dogs ; Gram-Negative Bacterial Infections/diagnosis ; Gram-Negative Bacterial Infections/drug therapy ; Humans
    Language English
    Publishing date 2021-01-26
    Publishing country England
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 2050436-6
    ISSN 1471-2415 ; 1471-2415
    ISSN (online) 1471-2415
    ISSN 1471-2415
    DOI 10.1186/s12886-021-01823-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Update on aqueous shunts in glaucoma.

    Mosaed, Sameh

    International ophthalmology clinics

    2011  Volume 51, Issue 3, Page(s) 155–164

    MeSH term(s) Equipment Design ; Glaucoma/surgery ; Glaucoma Drainage Implants/history ; Glaucoma Drainage Implants/standards ; Glaucoma Drainage Implants/trends ; History, 20th Century ; Humans ; Sclera/transplantation ; Surgical Flaps
    Language English
    Publishing date 2011
    Publishing country United States
    Document type Comparative Study ; Evaluation Studies ; Historical Article ; Journal Article
    ZDB-ID 207382-1
    ISSN 1536-9617 ; 0020-8167
    ISSN (online) 1536-9617
    ISSN 0020-8167
    DOI 10.1097/IIO.0b013e31821e5a79
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Acquired Optic Pits Associated with Laser-assisted

    Smith, Andrew K / Bussel, Igor / Ling, John / Mosaed, Sameh

    Journal of current glaucoma practice

    2021  Volume 14, Issue 3, Page(s) 106–108

    Abstract: Purpose: To present an association between acquired pits of the optic nerve (APON) and prior laser-assisted : Materials and methods: A retrospective case series of patients with an optic disc pit on clinical exam and a history of LASIK. Spectralis ... ...

    Abstract Purpose: To present an association between acquired pits of the optic nerve (APON) and prior laser-assisted
    Materials and methods: A retrospective case series of patients with an optic disc pit on clinical exam and a history of LASIK. Spectralis Optical Coherence Tomography images and Humphrey Visual Fields were reviewed from prior visits. Extended-depth optical coherence tomography was performed of the optic nerve head at subsequent visits after patients were identified.
    Results: Seven patients, aged 45-73 years, were identified each with unilateral optic disc pits. Optic disc pits were located inferior in six patients and centrally in one patient. All demonstrated thinning on optical coherence tomography and six patients had corresponding visual field defects. Four patients identified these defects after their LASIK procedure while two patients were unaware of their reproducible visual field defects. All patients were treated with drops initially. One patient underwent laser trabeculoplasty, and three underwent a trabeculectomy after demonstrating progression on maximum tolerated medical therapy.
    Conclusion: This series describes a possible association between LASIK and APON. Given the similarity and severity of vision loss associated with the optic nerve pits in these patients after LASIK, increased awareness and caution is suggested while considering LASIK in susceptible individuals.
    How to cite this article: Smith AK, Bussel I, Ling J,
    Language English
    Publishing date 2021-03-31
    Publishing country India
    Document type Case Reports
    ISSN 0974-0333
    ISSN 0974-0333
    DOI 10.5005/jp-journals-10078-1284
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: In Reply: Latanoprost-induced Skin Hypopigmentation.

    Lin, Mark / Schmutz, Mason / Mosaed, Sameh

    Journal of glaucoma

    2018  Volume 27, Issue 3, Page(s) e72–e73

    MeSH term(s) Albinism, Oculocutaneous ; Humans ; Hypopigmentation ; Intraocular Pressure ; Latanoprost ; Pigmentation Disorders
    Chemical Substances Latanoprost (6Z5B6HVF6O)
    Language English
    Publishing date 2018-01-10
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 913494-3
    ISSN 1536-481X ; 1057-0829
    ISSN (online) 1536-481X
    ISSN 1057-0829
    DOI 10.1097/IJG.0000000000000879
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Association of Retinopathy of Prematurity and Plateau iris.

    Nguyen, Van / Jwo, Kevin / Bhatt, Anand / Mosaed, Sameh

    Journal of glaucoma

    2019  Volume 28, Issue 7, Page(s) e121–e123

    Abstract: We present a case series describing a unique entity as it relates to plateau iris. There have been many established risk factors for plateau iris, but we present the following cases that describe patients with plateau iris in the setting of prematurity ... ...

    Abstract We present a case series describing a unique entity as it relates to plateau iris. There have been many established risk factors for plateau iris, but we present the following cases that describe patients with plateau iris in the setting of prematurity and/or retinopathy of prematurity as well as high myopia or emmetropia. We believe this to be a distinct form of plateau iris resulting from abnormal ciliary body and angle development in the preterm infant. Subjects were treated according to standard of care, with laser peripheral iridotomies, laser iridoplasty, and even glaucoma drainage implants, as indicated.
    MeSH term(s) Adolescent ; Adult ; Female ; Glaucoma, Angle-Closure/diagnosis ; Glaucoma, Angle-Closure/physiopathology ; Glaucoma, Angle-Closure/surgery ; Gonioscopy ; Humans ; Intraocular Pressure/physiology ; Iridectomy ; Iris/surgery ; Iris Diseases/diagnosis ; Iris Diseases/surgery ; Male ; Middle Aged ; Premature Birth ; Retinopathy of Prematurity/diagnosis ; Tonometry, Ocular
    Language English
    Publishing date 2019-03-28
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 913494-3
    ISSN 1536-481X ; 1057-0829
    ISSN (online) 1536-481X
    ISSN 1057-0829
    DOI 10.1097/IJG.0000000000001249
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