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  1. Article ; Online: Correction: Uncovering the Mechanism of Chinese Hawthorn Leaf on Myocardial Ischemia Based on Network Pharmacology, Molecular Docking Verification, and In Vitro Studies.

    Gao, Jingyun / Wang, Yueyue / Xiong, Hui / Zhao, Shengnan / He, Mingmei / He, Meiting / Pan, Haifeng

    Cardiovascular toxicology

    2024  

    Language English
    Publishing date 2024-04-25
    Publishing country United States
    Document type Published Erratum
    ZDB-ID 2036765-X
    ISSN 1559-0259 ; 1530-7905
    ISSN (online) 1559-0259
    ISSN 1530-7905
    DOI 10.1007/s12012-024-09851-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5817: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Reinvestigation on High-Valent Cobalt for the Degradation of Micropollutants in the Co(II)/Peroxymonosulfate System: Roles of Co(III).

    Cao, Yilong / Wang, Zhen / He, Shaoxiong / Shi, Lixuan / Guo, Kaiheng / Fang, Jingyun

    Environmental science & technology

    2024  

    Abstract: Recently, reactive cobalt (Co) species, including Co(IV)-oxo and Co(II)- ... ...

    Abstract Recently, reactive cobalt (Co) species, including Co(IV)-oxo and Co(II)-OOSO
    Language English
    Publishing date 2024-02-09
    Publishing country United States
    Document type Journal Article
    ISSN 1520-5851
    ISSN (online) 1520-5851
    DOI 10.1021/acs.est.3c10062
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Characterization of vB_ValM_PVA8, a broad-host-range bacteriophage infecting

    Fu, Jingyun / Li, Ying / Zhao, Lihong / Wu, Chunguang / He, Zengguo

    Frontiers in microbiology

    2023  Volume 14, Page(s) 1105924

    Abstract: Phage therapy was taken as an alternative strategy to antibiotics in shrimp farming for the control ... ...

    Abstract Phage therapy was taken as an alternative strategy to antibiotics in shrimp farming for the control of
    Language English
    Publishing date 2023-05-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2023.1105924
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Weakly Supervised Exaggeration Transfer for Caricature Generation With Cross-Modal Knowledge Distillation.

    Tong, Shuo / Liu, Han / He, Yuxin / Du, Chenxiao / Wang, Wenqing / Guo, Runyuan / Liu, Jingyun

    IEEE computer graphics and applications

    2024  Volume PP

    Abstract: Caricature generation aims to translate portrait photos into caricatures with exaggerated and hand-drawn artistic styles. Previous methods faced challenges in creating diverse and meaningful exaggeration effects, yielding unsatisfactory and ... ...

    Abstract Caricature generation aims to translate portrait photos into caricatures with exaggerated and hand-drawn artistic styles. Previous methods faced challenges in creating diverse and meaningful exaggeration effects, yielding unsatisfactory and uncontrollable results. To overcome this, we proposed ETCari, a novel weakly supervised exaggeration transfer network. ETCari enables the learning of diverse exaggeration caricature styles from various artists, better meeting individual customization requirements and achieving diversified exaggeration while retaining identity features. Specifically, we use the thin-plate spline control point deformation field as the ground truth, serving as the loss for weakly supervised learning to address the challenge of no labels. We convert input to an intermediate modality for domain adaptation, training a teacher model. Subsequently, we perform cross-modal knowledge distillation to train the student model, simplifying preprocessing during inference and avoiding the impact of face parser errors. Experiments on the WebCaricature dataset demonstrate that ETCari effectively performs exaggeration transfer, generating appealing caricatures.
    Language English
    Publishing date 2024-04-17
    Publishing country United States
    Document type Journal Article
    ISSN 1558-1756
    ISSN (online) 1558-1756
    DOI 10.1109/MCG.2024.3390121
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Uncovering the Mechanism of Chinese Hawthorn Leaf on Myocardial Ischemia Based on Network Pharmacology, Molecular Docking Verification, and In Vitro Studies.

    Gao, Jingyun / Wang, Yueyue / Xiong, Hui / Zhao, Shengnan / He, Mingmei / He, Meiting / Pan, Haifeng

    Cardiovascular toxicology

    2024  Volume 24, Issue 2, Page(s) 171–183

    Abstract: Hawthorn leaf has shown therapeutic effects in the patients with myocardial ischemia. Our study combines network pharmacology, molecular docking techniques, and in vitro experiment with the aim of revealing the mechanism of hawthorn leaves in the ... ...

    Abstract Hawthorn leaf has shown therapeutic effects in the patients with myocardial ischemia. Our study combines network pharmacology, molecular docking techniques, and in vitro experiment with the aim of revealing the mechanism of hawthorn leaves in the treatment of myocardial ischemia. The active ingredients and corresponding targets of hawthorn leaf through Traditional Chinese Medicine System Pharmacology and Swiss Target Prediction databases. Targets related to myocardial ischemia were retrieved by Gene Card, Online Mendelian Inheritance in Man, Disgenet, and Therapeutic Targets Database databases. Cytoscape software was used to construct an ingredient-target-organ network and enrichment analysis of common targets was analyzed. Molecular docking verification of the core compound and target interactions was performed using MOE software. In vitro cell experiment was performed to verify the findings from bioinformatics analysis. Six active components and 107 potential therapeutic targets were screened. The protein-protein interaction network analysis indicated that 10 targets, including AKT1 and EGFR, were hub genes. Quercetin, kaempferol and isorhamnetin were taken as core active components. Through pathway enrichment analysis, nearly 455 Gene Ontology entries and 77 Kyoto Encyclopedia of Genes and Genomes pathways were obtained, mainly including PI3K/Akt, estrogen and other signaling pathways. Molecular docking prediction showed that three main active ingredients were firmly combined with the core targets. Cellular experiments showed that quercetin alleviated oxidative damage in cells and regulated the expression of PI3K, P-AKT/AKT and Bax/Bcl-2 proteins. This study identified the potential targets of Hawthorn leaf against myocardial ischemia using network pharmacology and in vitro verification, which provided a new understanding of the pharmacological mechanisms of Hawthorn leaf in treatment of myocardial ischemia.
    MeSH term(s) Humans ; Molecular Docking Simulation ; Crataegus ; Network Pharmacology ; Phosphatidylinositol 3-Kinases ; Proto-Oncogene Proteins c-akt ; Quercetin/pharmacology ; Coronary Artery Disease ; Myocardial Ischemia/drug therapy ; Myocardial Ischemia/genetics ; Databases, Genetic ; Drugs, Chinese Herbal/pharmacology
    Chemical Substances Phosphatidylinositol 3-Kinases (EC 2.7.1.-) ; Proto-Oncogene Proteins c-akt (EC 2.7.11.1) ; Quercetin (9IKM0I5T1E) ; Drugs, Chinese Herbal
    Language English
    Publishing date 2024-02-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2036765-X
    ISSN 1559-0259 ; 1530-7905
    ISSN (online) 1559-0259
    ISSN 1530-7905
    DOI 10.1007/s12012-024-09825-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5817: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article: Mycoplasma genitalium

    Yu, Jianwei / Zhou, Yan / Luo, Haodang / Su, Xiaoling / Gan, Tian / Wang, Jingyun / Ye, Zufeng / Deng, Zhongliang / He, Jun

    Frontiers in microbiology

    2023  Volume 14, Page(s) 1098276

    Abstract: Mycoplasma ... ...

    Abstract Mycoplasma genitalium
    Language English
    Publishing date 2023-02-21
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2023.1098276
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Research progress in spike mutations of SARS-CoV-2 variants and vaccine development.

    He, Xuemei / He, Cai / Hong, Weiqi / Yang, Jingyun / Wei, Xiawei

    Medicinal research reviews

    2023  Volume 43, Issue 4, Page(s) 932–971

    Abstract: The coronavirus disease 2019 (COVID-19) pandemic can hardly end with the emergence of different variants over time. In the past 2 years, several variants of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), such as the Delta and Omicron ... ...

    Abstract The coronavirus disease 2019 (COVID-19) pandemic can hardly end with the emergence of different variants over time. In the past 2 years, several variants of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), such as the Delta and Omicron variants, have emerged with higher transmissibility, immune evasion and drug resistance, leading to higher morbidity and mortality in the population. The prevalent variants of concern (VOCs) share several mutations on the spike that can affect virus characteristics, including transmissibility, antigenicity, and immune evasion. Increasing evidence has demonstrated that the neutralization capacity of sera from COVID-19 convalescent or vaccinated individuals is decreased against SARS-CoV-2 variants. Moreover, the vaccine effectiveness of current COVID-19 vaccines against SARS-CoV-2 VOCs is not as high as that against wild-type SARS-CoV-2. Therefore, more attention might be paid to how the mutations impact vaccine effectiveness. In this review, we summarized the current studies on the mutations of the SARS-CoV-2 spike, particularly of the receptor binding domain, to elaborate on how the mutations impact the infectivity, transmissibility and immune evasion of the virus. The effects of mutations in the SARS-CoV-2 spike on the current therapeutics were highlighted, and potential strategies for future vaccine development were suggested.
    MeSH term(s) Humans ; SARS-CoV-2/genetics ; COVID-19/prevention & control ; COVID-19 Vaccines/genetics ; Vaccine Development ; Mutation
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2023-03-16
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 603210-2
    ISSN 1098-1128 ; 0198-6325
    ISSN (online) 1098-1128
    ISSN 0198-6325
    DOI 10.1002/med.21941
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1764: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Comparison of requirements for clinical study of SARS-CoV-2 antigen test kits in China, the USA and Europe.

    Lyu, Yunfeng / Zhu, Yuting / Zhang, Ying / Hou, Yuanyuan / Zhang, Yining / He, Jingyun / Deng, Gang

    Bioanalysis

    2023  Volume 15, Issue 10, Page(s) 581–589

    Abstract: Aims: ...

    Abstract Aims:
    MeSH term(s) Humans ; China ; Clinical Trials as Topic ; COVID-19/diagnosis ; Europe ; Immunologic Tests ; SARS-CoV-2 ; United States
    Language English
    Publishing date 2023-06-06
    Publishing country England
    Document type Journal Article ; Review
    ISSN 1757-6199
    ISSN (online) 1757-6199
    DOI 10.4155/bio-2023-0042
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Enhancing the Abatement of Permanganate-inert Micropollutants: Multiple Roles of Nascent Manganese Dioxide in Permanganate Oxidation.

    Wu, Sining / Guo, Kaiheng / Xie, Ruijie / He, Shaoxiong / Wei, Wenrui / Fang, Jingyun

    Water research

    2023  Volume 245, Page(s) 120562

    Abstract: Permanganate (Mn(VII)) is widely used as an oxidant in water treatment and usually reduced to nascent manganese dioxide ( ... ...

    Abstract Permanganate (Mn(VII)) is widely used as an oxidant in water treatment and usually reduced to nascent manganese dioxide (MnO
    Language English
    Publishing date 2023-08-31
    Publishing country England
    Document type Journal Article
    ZDB-ID 202613-2
    ISSN 1879-2448 ; 0043-1354
    ISSN (online) 1879-2448
    ISSN 0043-1354
    DOI 10.1016/j.watres.2023.120562
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 78/260: Show issues
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  10. Article: Exploring the Impact of Insertion/Deletion in

    Wang, Xinle / Li, Jingyun / Bai, Junyan / Chen, Mengke / Wang, Longwei / Fan, Hongdeng / Zeng, Fanlin / Lu, Xiaoning / He, Yuhan

    Animals : an open access journal from MDPI

    2023  Volume 13, Issue 19

    Abstract: This study aimed to identify InDels from ... ...

    Abstract This study aimed to identify InDels from the
    Language English
    Publishing date 2023-09-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606558-7
    ISSN 2076-2615
    ISSN 2076-2615
    DOI 10.3390/ani13193032
    Database MEDical Literature Analysis and Retrieval System OnLINE

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