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  1. Article ; Online: Story of magnesium for torsade de pointes.

    Tzivoni, Dan / Banai, Shmuel / Keren, Andre

    Heart rhythm

    2023  Volume 21, Issue 4, Page(s) 360–361

    MeSH term(s) Humans ; Torsades de Pointes/diagnosis ; Magnesium ; Electrocardiography
    Chemical Substances Magnesium (I38ZP9992A)
    Language English
    Publishing date 2023-09-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2229357-7
    ISSN 1556-3871 ; 1547-5271
    ISSN (online) 1556-3871
    ISSN 1547-5271
    DOI 10.1016/j.hrthm.2024.01.013
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    Zs.A 6278: Show issues Location:
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  2. Article: Drug-induced QT prolongation.

    Tzivoni, D

    The Israel Medical Association journal : IMAJ

    2001  Volume 3, Issue 6, Page(s) 472

    MeSH term(s) Anti-Arrhythmia Agents/adverse effects ; Humans ; Long QT Syndrome/chemically induced ; Torsades de Pointes/chemically induced
    Chemical Substances Anti-Arrhythmia Agents
    Language English
    Publishing date 2001-06
    Publishing country Israel
    Document type Comment ; Letter
    ZDB-ID 2008291-5
    ISSN 1565-1088 ; 0021-2180
    ISSN 1565-1088 ; 0021-2180
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Value and limitations of ambulatory ECG monitoring for assessment of myocardial ischemia.

    Tzivoni, D

    Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc

    2001  Volume 6, Issue 3, Page(s) 236–242

    Abstract: Ambulatory ECG monitoring (AEM) is the only available method to assess the presence and severity of myocardial ischemia during daily life. Several investigators have shown that the recording systems currently used can detect ischemic changes with similar ...

    Abstract Ambulatory ECG monitoring (AEM) is the only available method to assess the presence and severity of myocardial ischemia during daily life. Several investigators have shown that the recording systems currently used can detect ischemic changes with similar accuracy as treadmill exercise testing. Ischemic changes on AEM are, however, present in only 40%-60% of patients with coronary artery disease (CAD) and positive exercise tests. For this reason, and because of the high day-to-day variability in daily ischemic changes, AEM cannot be used as a screening tool for detecting CAD or for evaluating severity of ischemia in individual patients. In patients with proven CAD, ischemic changes on AEM are associated with an adverse outcome in patients with stable and unstable ischemic syndromes, and in postmyocardial infarction patients. Suppression of daily ischemia seems to be associated with improved outcome. The mechanism of daily ischemia is not identical to exercise-induced ischemia. In addition to increased demand, which is a major contributor to AEM detected-ischemia, increased coronary tone also seems to play a major role. AEM has been shown to be a useful and reliable tool to assess the efficacy of various antiischemic drugs.
    MeSH term(s) Electrocardiography, Ambulatory/standards ; Exercise Test/methods ; Humans ; Myocardial Ischemia/diagnosis
    Language English
    Publishing date 2001-07
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1325530-7
    ISSN 1542-474X ; 1082-720X
    ISSN (online) 1542-474X
    ISSN 1082-720X
    DOI 10.1111/j.1542-474x.2001.tb00114.x
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    Zs.A 4953: Show issues Location:
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  4. Article ; Online: Basic self-disorders in adolescence predict schizophrenia spectrum disorders in young adulthood: A 7-year follow-up study among non-psychotic help-seeking adolescents.

    Koren, Danny / Tzivoni, Yair / Schalit, Liat / Adres, Merav / Reznik, Noa / Apter, Alan / Parnas, Josef

    Schizophrenia research

    2019  Volume 216, Page(s) 97–103

    Abstract: Background and goals: Recent studies indicate that basic self-disorder (SD) is a core clinical phenotype of schizophrenia and its spectrum. The goal of the present study was to test the degree to which SD characterizes the pre-onset phase of ... ...

    Abstract Background and goals: Recent studies indicate that basic self-disorder (SD) is a core clinical phenotype of schizophrenia and its spectrum. The goal of the present study was to test the degree to which SD characterizes the pre-onset phase of schizophrenia-spectrum disorders (SSD). A secondary goal was to replicate previous findings regarding the long-term stability of SD.
    Method: To accomplish these goals, the long-term association of SD in adolescence with SSD seven years later was examined in a sample of 39 non-psychotic, help-seeking adolescents. SD was assessed with the Examination of Anomalous Self-Experience (EASE), and presence of schizophrenia-spectrum and other co-morbid illnesses in young adulthood was assessed with the Operational Criteria+ (OPCRIT+) checklist for psychotic and affective disorders.
    Results: Nine (23.1%) of the 39 participants were diagnosed as suffering from SSD (three Schizophrenia, three non-organic and non-affective psychotic disorder, and three schizotypal disorder) in young adulthood. A diagnosis of SSD in young adulthood was significantly predicted by SD, but not by prodromal symptoms in adolescence. The correlation between the EASE total score at adolescence and young adulthood was moderate and significant (r = 0.64, p < .001).
    Conclusions: These results provide first long-term prospective support, in a sample not enriched for risk for psychosis, for the possibility that SD is a clinical marker of risk for SSD. Also, they provide additional support for the longitudinal persistence of SD over time.
    MeSH term(s) Adolescent ; Adult ; Follow-Up Studies ; Humans ; Prodromal Symptoms ; Prospective Studies ; Psychotic Disorders/diagnosis ; Psychotic Disorders/epidemiology ; Schizophrenia/diagnosis ; Schizophrenia/epidemiology ; Young Adult
    Language English
    Publishing date 2019-12-27
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 639422-x
    ISSN 1573-2509 ; 0920-9964
    ISSN (online) 1573-2509
    ISSN 0920-9964
    DOI 10.1016/j.schres.2019.12.022
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    Zs.MO 543: Show issues

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  5. Article: Neostigmine induced coronary artery spasm: A case report and literature review.

    Kolker, Shimon / Tzivoni, Dan / Rosenmann, David / Meyler, Shmuel / Ioscovich, Alexander

    Journal of anaesthesiology, clinical pharmacology

    2017  Volume 33, Issue 3, Page(s) 402–405

    Abstract: Neostigmine is a cholinesterase inhibitor which does not cross the blood brain barrier and a commonly used for reversal of nondepolarizing muscle relaxants. In the following case report, we present a patient who developed coronary artery spasm, after the ...

    Abstract Neostigmine is a cholinesterase inhibitor which does not cross the blood brain barrier and a commonly used for reversal of nondepolarizing muscle relaxants. In the following case report, we present a patient who developed coronary artery spasm, after the administration of repeated doses of neostigmine. Ours is the first case to demonstrate such a longstanding coronary artery vasospasm that lasted several hours in response to neostigmine, resulting in myocardial damage and left ventricular dysfunction. We would like to draw the attention of the anesthesiologists to this rare effect that may lead to perioperative cardiac complications.
    Language English
    Publishing date 2017-08-09
    Publishing country India
    Document type Case Reports
    ZDB-ID 1401760-x
    ISSN 0970-9185
    ISSN 0970-9185
    DOI 10.4103/0970-9185.173337
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  6. Article: Myocardial preconditioning in humans.

    Tzivoni, D

    The Israel Medical Association journal : IMAJ

    2000  Volume 2, Issue 5, Page(s) 393–396

    Abstract: The exact role of myocardial preconditioning in patients with coronary artery disease is not clear. Preconditioning rapidly develops during coronary angioplasty. Myocardial preconditioning probably plays a role in reducing the myocardial infarct size in ... ...

    Abstract The exact role of myocardial preconditioning in patients with coronary artery disease is not clear. Preconditioning rapidly develops during coronary angioplasty. Myocardial preconditioning probably plays a role in reducing the myocardial infarct size in patients with preceding angina by direct effect, rendering the myocytes more resistant to ischemic injury, by acceleration of thrombolysis, and probably by the increasing recruitment of collaterals. It is also possible that the higher mortality among diabetic patients on sulfonylureas, and their worse outcome during acute myocardial infarction, are related to blockade of preconditioning [39,40]. Myocardial preconditioning does exist during daily life, explaining the well-known phenomenon of "walk-though angina" and the more common "walk-through ischemia." It is hoped that drugs that mimic or enhance preconditioning will be developed, which will provide powerful myocardial protection.
    MeSH term(s) Angioplasty, Balloon, Coronary ; Animals ; Coronary Artery Bypass ; Coronary Disease/therapy ; Humans ; Ischemic Preconditioning, Myocardial/methods ; Myocardial Infarction/prevention & control
    Language English
    Publishing date 2000-05
    Publishing country Israel
    Document type Journal Article ; Review
    ZDB-ID 2008291-5
    ISSN 1565-1088 ; 0021-2180
    ISSN 1565-1088 ; 0021-2180
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  7. Article: End organ protection by calcium-channel blockers.

    Tzivoni, D

    Clinical cardiology

    2000  Volume 24, Issue 2, Page(s) 102–106

    Abstract: In recent years, much attention has been given to end organ protection by antihypertensive, anti-heart failure, and anti-ischemic medications. This review describes the available information on end organ protection by calcium-channel blockers (CCBs). In ... ...

    Abstract In recent years, much attention has been given to end organ protection by antihypertensive, anti-heart failure, and anti-ischemic medications. This review describes the available information on end organ protection by calcium-channel blockers (CCBs). In normotensive patients and patients with hypertension treated with long-acting dihydropyridines, medial thickness was thinner than in patients treated with atenolol or in untreated hypertensive patients. Long-term treatment was associated with significant reduction in left ventricular mass. Calcium-channel blockers also improved endothelial-dependent relaxation and reversed the vasoconstrictive response to nitric oxide inhibitors. In diabetic patients, CCBs were effective in preserving kidney function and microalbuminurea. The combination of angiotensin-converting enzyme (ACE) inhibitors and CCBs was more effective than ACE inhibitors alone in preserving kidney function. In animal experiments, CCBs prevented development of coronary atheroschlerosis; however, in humans only limited data are available on their antiatherogenic effect. Some studies suggest that CCBs exert antiplatelets properties and may therefore be beneficial in patients with coronary artery disease.
    MeSH term(s) Angina Pectoris/drug therapy ; Arteriosclerosis/prevention & control ; Calcium Channel Blockers/adverse effects ; Calcium Channel Blockers/pharmacology ; Calcium Channel Blockers/therapeutic use ; Coronary Disease/prevention & control ; Endothelium, Vascular/drug effects ; Female ; Heart Failure/prevention & control ; Humans ; Hypertension/drug therapy ; Kidney Diseases/prevention & control ; Male ; Platelet Activation/drug effects
    Chemical Substances Calcium Channel Blockers
    Language English
    Publishing date 2000-10-24
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 391935-3
    ISSN 1932-8737 ; 0160-9289
    ISSN (online) 1932-8737
    ISSN 0160-9289
    DOI 10.1002/clc.4960240202
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    Zs.A 1423: Show issues Location:
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  8. Article: Circadian variations in total ischaemic burden and ischaemic threshold.

    Tzivoni, D

    European heart journal

    1996  Volume 17 Suppl G, Page(s) 59–63

    Abstract: Myocardial ischaemia in daily life varies according to a circadian rhythm and is induced by many factors, including both increased myocardial oxygen demand and changes in coronary tone. In most patients, ischaemia is induced by a combination of different ...

    Abstract Myocardial ischaemia in daily life varies according to a circadian rhythm and is induced by many factors, including both increased myocardial oxygen demand and changes in coronary tone. In most patients, ischaemia is induced by a combination of different contributing factors, although the relative contribution of each mechanism varies from patient to patient. Moreover, in the same individual, various episodes may be due to different mechanisms. The relative contributions of increased myocardial oxygen demand and decreased ischaemic threshold to the development of ischaemia in daily life can be assessed by continuous ambulatory ECG monitoring which may help to optimize medical anti-ischaemic therapy.
    MeSH term(s) Circadian Rhythm ; Electrocardiography, Ambulatory ; Humans ; Myocardial Ischemia/diagnosis ; Myocardial Ischemia/physiopathology ; Prognosis ; Quality of Life ; Risk Factors
    Language English
    Publishing date 1996-12
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 603098-1
    ISSN 1522-9645 ; 0195-668X
    ISSN (online) 1522-9645
    ISSN 0195-668X
    DOI 10.1093/eurheartj/17.suppl_g.59
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    Zs.MO 640: Show issues

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  9. Article: Cryo-Balloon Ablation of the Right Superior Pulmonary Vein Involving the Anterior Right Ganglionated Plexus for Speech and Breathing Induced Atrial Tachycardia.

    Medina, Aharon / Ilan, Mickey / Tzivoni, Dan

    Journal of atrial fibrillation

    2013  Volume 5, Issue 6, Page(s) 828

    Abstract: Targeting ganglionated plexi (GP) during catheter ablation of atrial fibrillation (AF) is associated with improved outcome. We present a patient with speech and breathing induced atrial tachycardia (AT) originating in the superior vena cava (SVC) and the ...

    Abstract Targeting ganglionated plexi (GP) during catheter ablation of atrial fibrillation (AF) is associated with improved outcome. We present a patient with speech and breathing induced atrial tachycardia (AT) originating in the superior vena cava (SVC) and the right superior pulmonary vein (RSPV), near the anatomical location of the anterior right GP (ARGP). The trigger for the arrhythmia appeared to be vagal discharge from the GP, possibly induced by local stretch. Ablation with a 28 mm cryo-balloon advanced to the RSPV orifice through a patent foramen ovale (PFO) abolished the arrhythmia, probably involving the underlying parasympathetic influx to the SVC and RSPV myocardial sleeves.
    Language English
    Publishing date 2013-04-06
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2451936-4
    ISSN 1941-6911
    ISSN 1941-6911
    DOI 10.4022/jafib.828
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  10. Article ; Online: Continuous ST-segment monitoring in contemporary acute coronary syndrome patients: the magic of MERLIN-TIMI 36.

    Tzivoni, Dan / Krucoff, Mitchell W

    Journal of the American College of Cardiology

    2009  Volume 53, Issue 16, Page(s) 1422–1424

    MeSH term(s) Acute Coronary Syndrome/diagnosis ; Acute Coronary Syndrome/epidemiology ; Electrocardiography, Ambulatory ; Humans
    Language English
    Publishing date 2009-04-21
    Publishing country United States
    Document type Comment ; Editorial
    ZDB-ID 605507-2
    ISSN 1558-3597 ; 0735-1097
    ISSN (online) 1558-3597
    ISSN 0735-1097
    DOI 10.1016/j.jacc.2009.01.039
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    Zs.MO 196: Show issues

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