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  1. Article ; Online: What Cardiothoracic Radiologists Should Know About Imaging in Transgender Patients.

    Carroll, Evelyn F / Massoth, Lucas R / Stowell, Justin T

    Journal of thoracic imaging

    2022  Volume 37, Issue 5, Page(s) 269–278

    Abstract: Transgender and gender diverse (TGD) individuals may undergo a wide range of care during gender transition including mental health counseling, gender-affirming hormonal therapy, and various surgeries. Hormone therapy effectively converts the hormonal ... ...

    Abstract Transgender and gender diverse (TGD) individuals may undergo a wide range of care during gender transition including mental health counseling, gender-affirming hormonal therapy, and various surgeries. Hormone therapy effectively converts the hormonal milieu into that of the affirmed gender and produces measurable alterations in serum markers for coronary artery disease and other hematologic conditions (eg, erythrocytosis, venous thrombosis). Although illegal in the United States, some transgender women may receive silicone injections for breast and soft tissue augmentation, which can lead to devastating local complications, as well as silicone migration, pulmonary embolism, systemic reactions, and death. Smoking rates are higher among transgender and sexual minority populations, placing them at elevated risk of smoking-related diseases, including lung cancer. Some opportunistic infections may be more common in the TGD populations, attributable to higher rates of coexisting infection with human immunodeficiency virus. Radiologists should be aware that these patients may develop cancer of their natal organs (eg, breast, prostate), especially as some of these tissues are not completely removed during gender-affirming surgery, which may manifest with thoracic involvement by secondary neoplasia. As more TGD patients seek medical care, thoracic radiologists can reasonably expect to interpret imaging performed in this population and should be aware of possible disease processes and potential complications of hormonal and surgical therapies.
    MeSH term(s) Diagnostic Imaging ; Female ; Humans ; Male ; Radiologists ; Silicones ; Transgender Persons/psychology ; United States
    Chemical Substances Silicones
    Language English
    Publishing date 2022-04-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 632900-7
    ISSN 1536-0237 ; 0883-5993
    ISSN (online) 1536-0237
    ISSN 0883-5993
    DOI 10.1097/RTI.0000000000000653
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Massive Splenomegaly from Disseminated

    Massoth, Lucas R / Louissaint, Abner

    The New England journal of medicine

    2020  Volume 382, Issue 11, Page(s) 1041

    MeSH term(s) Adult ; Diagnosis, Differential ; HIV Infections/complications ; Humans ; Male ; Mycobacterium avium-intracellulare Infection/complications ; Mycobacterium avium-intracellulare Infection/diagnostic imaging ; Mycobacterium avium-intracellulare Infection/drug therapy ; Splenomegaly/diagnostic imaging ; Splenomegaly/etiology
    Language English
    Publishing date 2020-03-08
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMicm1905550
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Secondary histiocytic sarcoma with BRAF

    Venkataraman, Vinayak / Massoth, Lucas R / Sullivan, Ryan J / Friedmann, Alison M

    Pediatric blood & cancer

    2021  Volume 68, Issue 10, Page(s) e29166

    MeSH term(s) Histiocytic Sarcoma/drug therapy ; Histiocytic Sarcoma/genetics ; Humans ; Mutation ; Proto-Oncogene Proteins B-raf/genetics ; Sarcoma ; TOR Serine-Threonine Kinases/genetics
    Chemical Substances MTOR protein, human (EC 2.7.1.1) ; BRAF protein, human (EC 2.7.11.1) ; Proto-Oncogene Proteins B-raf (EC 2.7.11.1) ; TOR Serine-Threonine Kinases (EC 2.7.11.1)
    Language English
    Publishing date 2021-06-01
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2131448-2
    ISSN 1545-5017 ; 1545-5009
    ISSN (online) 1545-5017
    ISSN 1545-5009
    DOI 10.1002/pbc.29166
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Case 31-2021: A 21-Year-Old Man with Sore Throat, Epistaxis, and Oropharyngeal Petechiae.

    Hock, Hanno / Kelly, Hillary R / Meyerowitz, Eric A / Frigault, Matthew J / Massoth, Lucas R

    The New England journal of medicine

    2021  Volume 385, Issue 16, Page(s) 1511–1520

    MeSH term(s) Anemia, Aplastic/diagnosis ; Anemia, Aplastic/etiology ; Anemia, Aplastic/therapy ; Bone Marrow Examination ; COVID-19/complications ; COVID-19/diagnosis ; COVID-19 Nucleic Acid Testing ; Diagnosis, Differential ; Epistaxis/etiology ; Humans ; Male ; Oropharynx/pathology ; Pharyngitis/etiology ; Purpura/etiology ; SARS-CoV-2/isolation & purification ; Sickle Cell Trait/complications ; Stem Cell Transplantation ; Young Adult
    Language English
    Publishing date 2021-09-27
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMcpc2027096
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Secondary histiocytic sarcoma with BRAF

    Venkataraman, Vinayak / Massoth, Lucas R / Sullivan, Ryan J / Friedmann, Alison M

    Pediatric blood & cancer

    2020  Volume 67, Issue 5, Page(s) e28200

    MeSH term(s) Amino Acid Substitution ; Histiocytic Sarcoma/drug therapy ; Histiocytic Sarcoma/genetics ; Histiocytic Sarcoma/metabolism ; Histiocytic Sarcoma/pathology ; Humans ; Imidazoles/administration & dosage ; Infant ; Male ; Mutation, Missense ; Neoplasms, Second Primary/drug therapy ; Neoplasms, Second Primary/genetics ; Neoplasms, Second Primary/metabolism ; Neoplasms, Second Primary/pathology ; Oximes/administration & dosage ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/drug therapy ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/genetics ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/metabolism ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/pathology ; Proto-Oncogene Proteins B-raf/genetics ; Proto-Oncogene Proteins B-raf/metabolism ; Pyridones/administration & dosage ; Pyrimidinones/administration & dosage
    Chemical Substances Imidazoles ; Oximes ; Pyridones ; Pyrimidinones ; trametinib (33E86K87QN) ; BRAF protein, human (EC 2.7.11.1) ; Proto-Oncogene Proteins B-raf (EC 2.7.11.1) ; dabrafenib (QGP4HA4G1B)
    Language English
    Publishing date 2020-02-09
    Publishing country United States
    Document type Case Reports ; Letter
    ZDB-ID 2131448-2
    ISSN 1545-5017 ; 1545-5009
    ISSN (online) 1545-5017
    ISSN 1545-5009
    DOI 10.1002/pbc.28200
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Case 6-2021: A 65-Year-Old Man with Eye Pain and Decreased Vision.

    Bouffard, Marc A / Chwalisz, Bart K / Romero, Javier M / Arrillaga-Romany, Isabel C / Massoth, Lucas R

    The New England journal of medicine

    2021  Volume 384, Issue 8, Page(s) 745–753

    MeSH term(s) Adenine/analogs & derivatives ; Adenine/therapeutic use ; Aged ; Blood Cell Count ; Central Nervous System Neoplasms/complications ; Central Nervous System Neoplasms/diagnosis ; Central Nervous System Neoplasms/drug therapy ; Cerebrospinal Fluid/cytology ; Diagnosis, Differential ; Eye Diseases/etiology ; Eye Pain ; Humans ; Magnetic Resonance Imaging ; Male ; Optic Disk/diagnostic imaging ; Optic Nerve/diagnostic imaging ; Optic Nerve/pathology ; Pain/etiology ; Piperidines/therapeutic use ; Tomography, X-Ray Computed ; Vision Disorders/etiology ; Waldenstrom Macroglobulinemia/complications ; Waldenstrom Macroglobulinemia/diagnosis ; Waldenstrom Macroglobulinemia/drug therapy
    Chemical Substances Piperidines ; ibrutinib (1X70OSD4VX) ; Adenine (JAC85A2161)
    Language English
    Publishing date 2021-02-24
    Publishing country United States
    Document type Case Reports ; Clinical Conference ; Journal Article
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMcpc2027089
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Case 7-2019: A 73-Year-Old Woman with Swelling of the Right Groin and Fever.

    Soumerai, Jacob D / Tajmir, Shahein H / Hirsch, Martin S / Massoth, Lucas R

    The New England journal of medicine

    2019  Volume 380, Issue 9, Page(s) 859–868

    MeSH term(s) Aged ; Biopsy ; Diagnosis, Differential ; Disease Progression ; Edema/etiology ; Female ; Fever/etiology ; Groin ; Herpesviridae Infections/complications ; Herpesviridae Infections/diagnosis ; Humans ; Leukemia, Lymphocytic, Chronic, B-Cell/complications ; Lymph Nodes/pathology ; Lymphadenitis/complications ; Lymphadenitis/diagnosis ; Positron Emission Tomography Computed Tomography ; Positron-Emission Tomography ; Simplexvirus/isolation & purification
    Language English
    Publishing date 2019-02-01
    Publishing country United States
    Document type Case Reports ; Clinical Conference ; Journal Article
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMcpc1816408
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Case 13-2019: A 54-Year-Old Man with Alcohol Withdrawal and Altered Mental Status.

    Fenves, Andrew Z / Mojtahed, Amirkasra / Nisavic, Mladen / Massoth, Lucas R

    The New England journal of medicine

    2019  Volume 380, Issue 17, Page(s) 1657–1665

    MeSH term(s) 2-Propanol/chemistry ; 2-Propanol/metabolism ; 2-Propanol/poisoning ; Acetone/metabolism ; Acid-Base Equilibrium ; Acidosis/chemically induced ; Acidosis/diagnosis ; Alcohol Withdrawal Delirium/drug therapy ; Alcohol Withdrawal Delirium/psychology ; Alcoholism/complications ; Diagnosis, Differential ; Ethanol/blood ; Hand Sanitizers/adverse effects ; Homeless Persons ; Humans ; Male ; Middle Aged ; Phenobarbital/therapeutic use ; Poisoning/diagnosis ; Radiography, Abdominal ; Tachycardia/chemically induced ; Tomography, X-Ray Computed
    Chemical Substances Hand Sanitizers ; Acetone (1364PS73AF) ; Ethanol (3K9958V90M) ; 2-Propanol (ND2M416302) ; Phenobarbital (YQE403BP4D)
    Language English
    Publishing date 2019-04-24
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMcpc1900591
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Peripheral blood morphologic findings in patients with COVID-19.

    Sadigh, Sam / Massoth, Lucas R / Christensen, Bianca B / Stefely, Jonathan A / Keefe, Joan / Sohani, Aliyah R

    International journal of laboratory hematology

    2020  Volume 42, Issue 6, Page(s) e248–e251

    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Betacoronavirus ; Blood Cell Count ; Blood Cells/ultrastructure ; COVID-19 ; Cell Lineage ; Cell Size ; Coronavirus Infections/blood ; Coronavirus Infections/therapy ; Extracorporeal Membrane Oxygenation ; Female ; Hematopoiesis ; Humans ; Male ; Middle Aged ; Neutrophils/ultrastructure ; Pandemics ; Plasma Cells/ultrastructure ; Pneumonia, Viral/blood ; Pneumonia, Viral/therapy ; SARS-CoV-2 ; Sensitivity and Specificity
    Keywords covid19
    Language English
    Publishing date 2020-07-30
    Publishing country England
    Document type Letter
    ZDB-ID 2268590-X
    ISSN 1751-553X ; 1751-5521 ; 0141-9854
    ISSN (online) 1751-553X
    ISSN 1751-5521 ; 0141-9854
    DOI 10.1111/ijlh.13300
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Multiple calcifying fibrous pseudotumors of the pleura: ultrastructural analysis provides insight on mechanism of dissemination.

    Massoth, Lucas R / Selig, Martin K / Little, Brent P / Chebib, Ivan / Kradin, Richard L

    Ultrastructural pathology

    2020  Volume 43, Issue 4-5, Page(s) 154–161

    Abstract: Calcifying fibrous pseudotumor (CFP) is a rare, benign soft tissue tumor that may uncommonly arise in the pleura. These tumors can show multifocal dissemination across the pleural surface, but the mechanism underlying this dissemination is unclear. ... ...

    Abstract Calcifying fibrous pseudotumor (CFP) is a rare, benign soft tissue tumor that may uncommonly arise in the pleura. These tumors can show multifocal dissemination across the pleural surface, but the mechanism underlying this dissemination is unclear. Review of previously reported cases of pleural CFP demonstrates a strong predilection for basal and diaphragmatic pleural surfaces, and a significantly higher rate of multifocality compared with other locations. We present a 59-year-old male with multiple CFP of the pleura. Reactive-appearing adhesions spanning the pleural surfaces were present, and by electron microscopy, were involved by tumor. We suggest this is the likely mode of dissemination across the pleural surfaces.
    MeSH term(s) Calcinosis/pathology ; Carcinoma, Renal Cell/pathology ; Humans ; Incidental Findings ; Kidney Neoplasms/pathology ; Male ; Microscopy, Electron, Transmission ; Middle Aged ; Neoplasms, Multiple Primary/pathology ; Pleural Neoplasms/pathology ; Pleural Neoplasms/ultrastructure ; Soft Tissue Neoplasms/pathology ; Soft Tissue Neoplasms/ultrastructure
    Language English
    Publishing date 2020-02-21
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 603269-2
    ISSN 1521-0758 ; 0191-3123
    ISSN (online) 1521-0758
    ISSN 0191-3123
    DOI 10.1080/01913123.2019.1687631
    Database MEDical Literature Analysis and Retrieval System OnLINE

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