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Article ; Online: Comparison of the Clinical Performances of the Abbott Alinity IgG, Abbott Architect IgM, and Roche Elecsys Total SARS-CoV-2 Antibody Assays.

Harley, Kellisha / Gunsolus, Ian L

2020 Volume 59, Issue 1

Abstract: Critical evaluation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) serologic assays is needed to guide clinical decision-making and ensure that these assays provide optimal benefit to patients and the public. Here, three commercially ... ...

Abstract	Critical evaluation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) serologic assays is needed to guide clinical decision-making and ensure that these assays provide optimal benefit to patients and the public. Here, three commercially available assays with widespread distribution capabilities are compared. A total of 667 specimens, 103 from patients with confirmed SARS-CoV-2 infections and 564 collected prior to the emergence of SARS-CoV-2, were analyzed in parallel using the Roche Elecsys SARS-CoV-2 total antibody and Abbott Alinity SARS-CoV-2 IgG assays; a subset of 55 samples from patients with confirmed SARS-CoV-2 infections was additionally evaluated using the Abbott Architect SARS-CoV-2 IgM assay. Qualitative agreement between the Abbott IgG and Roche total antibody assays was 98.7% (658/667), with Cohen's kappa value of 0.919 (95% confidence interval [CI], 0.867 to 0.972). Qualitative agreements with the Abbott IgM assay were 92.7% (51/55, Abbott IgG) and 85.5% (47/55, Roche total antibody). Diagnostic specificities determined using pre-COVID-19 samples for the Abbott IgG and Roche total antibody assays were 99.65% (95% CI, 98.72 to 99.90%) and 100.00% (95% CI, 99.32 to 100.00%), respectively, spanning claims made by each manufacturer. Diagnostic sensitivities increased for all three assays with increasing time since the onset of symptoms. Among 51 patients with confirmed SARS-CoV-2 infections, 23 (45.1%), 24 (47.1%), and 22 (43.1%) were reactive by the Abbott IgG, Roche total antibody, and Abbott IgM assays, respectively, with sampling times 0 to 56 days post-positive PCR (median/mean, 2/6.2 days). Combining IgG and IgM screening identified 4/55 additional samples with detectable antibodies that would not have been observed using the assays independently. Notably, one immunocompromised patient with confirmed SARS-CoV-2 infection showed no detectable antibodies using any of the three assays 43 days after onset of symptoms.
MeSH term(s)	Antibodies, Viral/blood ; COVID-19/diagnosis ; COVID-19 Serological Testing/methods ; Humans ; Immunoglobulin G/blood ; Immunoglobulin M/blood ; SARS-CoV-2/immunology ; Sensitivity and Specificity
Chemical Substances	Antibodies, Viral ; Immunoglobulin G ; Immunoglobulin M
Keywords	covid19
Language	English
Publishing date	2020-12-17
Publishing country	United States
Document type	Comparative Study ; Journal Article
ZDB-ID	390499-4
ISSN	1098-660X ; 0095-1137
ISSN (online)	1098-660X
ISSN	0095-1137
DOI	10.1128/JCM.02104-20
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Article: Comparison of the Clinical Performance of the Abbott Alinity IgG, Abbott Architect IgM, and Roche Elecsys Total SARS-CoV-2 Antibody Assays

Harley, Kellisha / Gunsolus, Ian

J. clin. microbiol

Abstract: Critical evaluation of SARS-CoV-2 serologic assays is needed to guide clinical decision-making and ensure these assays provide optimal benefit to patients and the public. Here, three commercially available assays with widespread distribution capabilities ...

Abstract	Critical evaluation of SARS-CoV-2 serologic assays is needed to guide clinical decision-making and ensure these assays provide optimal benefit to patients and the public. Here, three commercially available assays with widespread distribution capabilities are compared. A total of 667 specimens, 103 from patients with confirmed SARS-CoV-2 infections and 564 collected prior to the emergence of SARS-CoV-2, were analyzed in parallel using the Roche Elecsys SARS-CoV-2 Total Antibody and Abbott Alinity SARS-CoV-2 IgG assays; a subset of 55 samples from patients with confirmed SARS-CoV-2 infections was additionally evaluated using the Abbott Architect SARS-CoV-2 IgM assay. Qualitative percent agreement between the Abbott IgG and Roche total antibody assays was 98.7% (658/667), with Cohen's kappa 0.919 (95% CI 0.867-0.972). Qualitative percent agreement with the Abbott IgM assay was 92.7% (51/55, Abbott IgG) and 85.5% (47/55, Roche total antibody). Diagnostic specificities determined using pre-COVID-19 samples for the Abbott IgG and Roche total antibody assays were 99.65% (95% CI 98.72-99.90%) and 100.00% (95% CI 99.32-100.00%), respectively, spanning claims made by each manufacturer. Diagnostic sensitivities increased for all three assays with increasing time since the onset of symptoms. Among 51 patients with confirmed SARS-CoV-2 infections, 23 (45.1%), 24 (47.1%), and 22 (43.1%) were reactive by the Abbott IgG, Roche total antibody, and Abbott IgM assays, respectively, with sampling times 0-56 days post-positive PCR (median/mean 2/6.2 days). Combining IgG and IgM screening identified 4/55 additional samples with detectable antibodies that would not have been observed using the assays independently. Notably, one immunocompromised patient with confirmed SARS-CoV-2 infection showed no detectable antibodies using any of the three assays 43 days after onset of symptoms.
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #892299
Database	COVID19

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Article ; Online: Comparison of the Clinical Performance of the Abbott Alinity IgG, Abbott Architect IgM, and Roche Elecsys Total SARS-CoV-2 Antibody Assays

Harley, Kellisha / Gunsolus, Ian

Journal of Clinical Microbiology ; ISSN 0095-1137 1098-660X

2020

Abstract	Critical evaluation of SARS-CoV-2 serologic assays is needed to guide clinical decision-making and ensure these assays provide optimal benefit to patients and the public. Here, three commercially available assays with widespread distribution capabilities are compared. A total of 667 specimens, 103 from patients with confirmed SARS-CoV-2 infections and 564 collected prior to the emergence of SARS-CoV-2, were analyzed in parallel using the Roche Elecsys SARS-CoV-2 Total Antibody and Abbott Alinity SARS-CoV-2 IgG assays; a subset of 55 samples from patients with confirmed SARS-CoV-2 infections was additionally evaluated using the Abbott Architect SARS-CoV-2 IgM assay. Qualitative percent agreement between the Abbott IgG and Roche total antibody assays was 98.7% (658/667), with Cohen's kappa 0.919 (95% CI 0.867-0.972). Qualitative percent agreement with the Abbott IgM assay was 92.7% (51/55, Abbott IgG) and 85.5% (47/55, Roche total antibody). Diagnostic specificities determined using pre-COVID-19 samples for the Abbott IgG and Roche total antibody assays were 99.65% (95% CI 98.72-99.90%) and 100.00% (95% CI 99.32-100.00%), respectively, spanning claims made by each manufacturer. Diagnostic sensitivities increased for all three assays with increasing time since the onset of symptoms. Among 51 patients with confirmed SARS-CoV-2 infections, 23 (45.1%), 24 (47.1%), and 22 (43.1%) were reactive by the Abbott IgG, Roche total antibody, and Abbott IgM assays, respectively, with sampling times 0-56 days post-positive PCR (median/mean 2/6.2 days). Combining IgG and IgM screening identified 4/55 additional samples with detectable antibodies that would not have been observed using the assays independently. Notably, one immunocompromised patient with confirmed SARS-CoV-2 infection showed no detectable antibodies using any of the three assays 43 days after onset of symptoms.
Keywords	Microbiology (medical) ; covid19
Language	English
Publisher	American Society for Microbiology
Publishing country	us
Document type	Article ; Online
DOI	10.1128/jcm.02104-20
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Article ; Online: Independent and combined effects of biotin and hemolysis on high-sensitivity cardiac troponin assays.

Harley, Kellisha / Bissonnette, Sarah / Inzitari, Rosanna / Schulz, Karen / Apple, Fred S / Kavsak, Peter A / Gunsolus, Ian L

Clinical chemistry and laboratory medicine

2021 Volume 59, Issue 8, Page(s) 1431–1443

Abstract: Objectives: This study compared the independent and combined effects of hemolysis and biotin on cardiac troponin measurements across nine high-sensitivity cardiac troponin (hs-cTn) assays.: Methods: Parallel cTn measurements were made in pooled ... ...

Abstract	Objectives: This study compared the independent and combined effects of hemolysis and biotin on cardiac troponin measurements across nine high-sensitivity cardiac troponin (hs-cTn) assays. Methods: Parallel cTn measurements were made in pooled lithium heparin plasma spiked with hemolysate and/or biotin using nine hs-cTn assays: Abbott Alinity, Abbott ARCHITECT i2000, Beckman Access 2, Ortho VITROS XT 7600, Siemens Atellica, Siemens Centaur, Siemens Dimension EXL cTnI, and two Roche Cobas e 411 Elecsys Troponin T-hs cTnT assays (outside US versions, with and without increased biotin tolerance). Absolute and percent cTn recovery relative to two baseline concentrations were determined in spiked samples and compared to manufacturer's claims. Results: All assays except the Ortho VITROS XT 7600 showed hemolysis and biotin interference thresholds equivalent to or greater than manufacturer's claims. While imprecision confounded analysis of Ortho VITROS XT 7600 data, evidence of biotin interference was lacking. Increasing biotin concentration led to decreasing cTn recovery in three assays, specifically both Roche Cobas e 411 Elecsys Troponin T-hs assays and the Siemens Dimension EXL. While one of the Roche assays was the most susceptible to biotin among the nine studied, a new version showed reduced biotin interference by approximately 100-fold compared to its predecessor. Increasing hemolysis also generally led to decreasing cTn recovery for susceptible assays, specifically the Beckman Access 2, Ortho VITROS XT 7600, and both Roche Cobas e 411 Elecsys assays. Equivalent biotin and hemolysis interference thresholds were observed at the two cTn concentrations considered for all but two assays (Beckman Access 2 and Ortho VITROS XT 7600). When biotin and hemolysis were present in combination, biotin interference thresholds decreased with increasing hemolysis for two susceptible assays (Roche Cobas e 411 Elecsys and Siemens Dimension EXL). Conclusions: Both Roche Cobas e 411 Elecsys as well as Ortho VITROS XT assays were susceptible to interference from
MeSH term(s)	Biotin ; Hemolysis ; Humans ; Laboratories, Clinical ; Troponin I ; Troponin T
Chemical Substances	Troponin I ; Troponin T ; Biotin (6SO6U10H04)
Language	English
Publishing date	2021-03-25
Publishing country	Germany
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1418007-8
ISSN	1437-4331 ; 1434-6621 ; 1437-8523
ISSN (online)	1437-4331
ISSN	1434-6621 ; 1437-8523
DOI	10.1515/cclm-2021-0124
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Zs.A 121: Show issues

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Article ; Online: Caring for aging parents in the last years of life.

Roberts, Harley L / Bollens-Lund, Evan / Ornstein, Katherine A / Kelley, Amy S

Journal of the American Geriatrics Society

2023 Volume 71, Issue 9, Page(s) 2871–2877

Abstract: Background: Adult children provide a large portion of end-of-life caregiving for older adults and make up the majority of caregivers for adults with dementia. Yet research has been limited to the hours of care that primary caregivers provide, neglecting ...

Abstract	Background: Adult children provide a large portion of end-of-life caregiving for older adults and make up the majority of caregivers for adults with dementia. Yet research has been limited to the hours of care that primary caregivers provide, neglecting the other ways adult children provide caregiving support. This study aims to describe the caregiving support adult children provide to their parents at the end of life and characterize differences by race and ethnicity and dementia status. Methods: We conducted a retrospective study using survey responses from the Health and Retirement Study between 2002 and 2018. The sample population (n = 8040) included decedents aged 65 with at least one living adult child at their time of death. Caregiving support was defined as providing financial support, providing help with basic or instrumental activities of daily living (ADLs or IADLs), or coresiding with the care recipient. Respondents were stratified by self-identified race and ethnicity as Hispanic, non-Hispanic White, or non-Hispanic Black. Respondents were further stratified by dementia and marital status. Results: Black and Hispanic respondents without dementia were more likely to report receiving financial help from (28.0% and 25.9%) or coresiding with their adult children (38.9% and 49.7%) compared to White respondents (15.0% receiving financial help and 23.3% coresiding) (p < 0.05). Among respondents with dementia, 47.1% of both Black and Hispanic respondents reported coresiding with their adult children, compared to only 24.6% of White respondents (p < 0.05). Notably, married Black and Hispanic respondents reported significantly higher rates of all support types compared to married White respondents (p < 0.05). Conclusions: The majority of older adults at the end of life receive some form of care and support from their adult children, with Black and Hispanic older adults receiving particularly high rates of care and support from their adult children regardless of dementia or marital status.
MeSH term(s)	Humans ; Aged ; Retrospective Studies ; Activities of Daily Living ; Parents ; Caregivers ; Aging ; Dementia ; Death
Language	English
Publishing date	2023-05-24
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
ZDB-ID	80363-7
ISSN	1532-5415 ; 0002-8614
ISSN (online)	1532-5415
ISSN	0002-8614
DOI	10.1111/jgs.18415
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Ud II Zs.168: Show issues

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Article ; Online: Electro-mechanical coupling of KCNQ channels is a target of epilepsy-associated mutations and retigabine.

Yang, Nien-Du / Kanyo, Richard / Zhao, Lu / Li, Jingru / Kang, Po Wei / Dou, Alex Kelly / White, Kelli McFarland / Shi, Jingyi / Nerbonne, Jeanne M / Kurata, Harley T / Cui, Jianmin

Science advances

2022 Volume 8, Issue 29, Page(s) eabo3625

Abstract: KCNQ2 and KCNQ3 form the M-channels that are important in regulating neuronal excitability. Inherited mutations that alter voltage-dependent gating of M-channels are associated with neonatal epilepsy. In the homolog KCNQ1 channel, two steps of voltage ... ...

Abstract	KCNQ2 and KCNQ3 form the M-channels that are important in regulating neuronal excitability. Inherited mutations that alter voltage-dependent gating of M-channels are associated with neonatal epilepsy. In the homolog KCNQ1 channel, two steps of voltage sensor activation lead to two functionally distinct open states, the intermediate-open (IO) and activated-open (AO), which define the gating, physiological, and pharmacological properties of KCNQ1. However, whether the M-channel shares the same mechanism is unclear. Here, we show that KCNQ2 and KCNQ3 feature only a single conductive AO state but with a conserved mechanism for the electro-mechanical (E-M) coupling between voltage sensor activation and pore opening. We identified some epilepsy-linked mutations in KCNQ2 and KCNQ3 that disrupt E-M coupling. The antiepileptic drug retigabine rescued KCNQ3 currents that were abolished by a mutation disrupting E-M coupling, suggesting that modulating the E-M coupling in KCNQ channels presents a potential strategy for antiepileptic therapy.
Language	English
Publishing date	2022-07-20
Publishing country	United States
Document type	Journal Article
ZDB-ID	2810933-8
ISSN	2375-2548 ; 2375-2548
ISSN (online)	2375-2548
ISSN	2375-2548
DOI	10.1126/sciadv.abo3625
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Article ; Online: Repopulating Microglia Promote Brain Repair in an IL-6-Dependent Manner.

Willis, Emily F / MacDonald, Kelli P A / Nguyen, Quan H / Garrido, Adahir Labrador / Gillespie, Ellen R / Harley, Samuel B R / Bartlett, Perry F / Schroder, Wayne A / Yates, Abi G / Anthony, Daniel C / Rose-John, Stefan / Ruitenberg, Marc J / Vukovic, Jana

Cell

2020 Volume 180, Issue 5, Page(s) 833–846.e16

Abstract: Cognitive dysfunction and reactive microglia are hallmarks of traumatic brain injury (TBI), yet whether these cells contribute to cognitive deficits and secondary inflammatory pathology remains poorly understood. Here, we show that removal of microglia ... ...

Abstract	Cognitive dysfunction and reactive microglia are hallmarks of traumatic brain injury (TBI), yet whether these cells contribute to cognitive deficits and secondary inflammatory pathology remains poorly understood. Here, we show that removal of microglia from the mouse brain has little effect on the outcome of TBI, but inducing the turnover of these cells through either pharmacologic or genetic approaches can yield a neuroprotective microglial phenotype that profoundly aids recovery. The beneficial effects of these repopulating microglia are critically dependent on interleukin-6 (IL-6) trans-signaling via the soluble IL-6 receptor (IL-6R) and robustly support adult neurogenesis, specifically by augmenting the survival of newborn neurons that directly support cognitive function. We conclude that microglia in the mammalian brain can be manipulated to adopt a neuroprotective and pro-regenerative phenotype that can aid repair and alleviate the cognitive deficits arising from brain injury.
MeSH term(s)	Animals ; Brain/growth & development ; Brain/pathology ; Brain Injuries, Traumatic/genetics ; Brain Injuries, Traumatic/pathology ; Brain Injuries, Traumatic/therapy ; Cognitive Dysfunction/genetics ; Cognitive Dysfunction/pathology ; Cognitive Dysfunction/therapy ; Disease Models, Animal ; Humans ; Inflammation/genetics ; Inflammation/pathology ; Interleukin-6/genetics ; Mice ; Microglia/metabolism ; Microglia/pathology ; Neurons/metabolism ; Neurons/pathology ; Neuroprotective Agents/therapeutic use ; Receptors, Interleukin-6/genetics ; Regeneration/genetics ; Signal Transduction/genetics
Chemical Substances	Il6ra protein, mouse ; Interleukin-6 ; Neuroprotective Agents ; Receptors, Interleukin-6
Language	English
Publishing date	2020-03-03
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	187009-9
ISSN	1097-4172 ; 0092-8674
ISSN (online)	1097-4172
ISSN	0092-8674
DOI	10.1016/j.cell.2020.02.013
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Zs.A 1167: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MG 58: Show issues

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Article ; Online: Cell-free DNA and circulating tumor cell kinetics in a pre-clinical head and neck Cancer model undergoing radiation therapy.

Muhanna, Nidal / Eu, Donovan / Chan, Harley H L / Douglas, Catriona / Townson, Jason L / Di Grappa, Marco A / Mohamadi, Reza M / Kelley, Shana O / Bratman, Scott V / Irish, Jonathan C

BMC cancer

2021 Volume 21, Issue 1, Page(s) 1075

Abstract: Background: Monitoring circulating tumor DNA (ctDNA) and circulating tumor cells (CTCs), known as liquid biopsies, continue to be developed as diagnostic and prognostic markers for a wide variety of cancer indications, mainly due to their minimally ... ...

Abstract	Background: Monitoring circulating tumor DNA (ctDNA) and circulating tumor cells (CTCs), known as liquid biopsies, continue to be developed as diagnostic and prognostic markers for a wide variety of cancer indications, mainly due to their minimally invasive nature and ability to offer a wide range of phenotypic and genetic information. While liquid biopsies maintain significant promising benefits, there is still limited information regarding the kinetics of ctDNA and CTCs following radiation therapy which remains a vital treatment modality in head and neck cancers. This study aims to describe the kinetics of ctDNA and CTCs following radiation exposure in a preclinical rabbit model with VX2 induced buccal carcinoma. Methods: Seven rabbits were inoculated with VX2 cells in the buccal mucosa and subjected to radiation. At selected time points, blood sampling was performed to monitor differing levels of ctDNA and CTC. Plasma ctDNA was measured with quantitative PCR for papillomavirus E6 while CTCs were quantified using an immunomagnetic nanoparticles within a microfluidic device. Comparisons of CTC detection with EpCAM compared to multiple surface markers (EGFR, HER2 and PSMA) was evaluated and correlated with the tumor size. Results: Plasma ctDNA reflects the overall tumor burden within the animal model. Analysis of correlations between ctDNA with tumor and lymph node volumes showed a positive correlation (R = 0.452 and R = 0.433 [p < 0.05]), respectively. Over the course of treatment, ctDNA levels declined and quickly becomes undetectable following tumor eradication. While during the course of treatment, ctDNA levels were noted to rise particularly upon initiation of radiation following scheduled treatment breaks. Levels of CTCs were observed to increase 1 week following inoculation of tumor to the primary site. For CTC detection, the use of multiple surface markers showed a greater sensitivity when compared to detection using only EpCAM. Plasma CTC levels remained elevated following radiation therapy which may account for an increased shedding of CTCs following radiation. Conclusion: This study demonstrates the utility of ctDNA and CTCs detection in response to radiation treatment in a preclinical head and neck model, allowing for better understanding of liquid biopsy applications in both clinical practice and research development.
MeSH term(s)	Animals ; Biomarkers, Tumor/blood ; Carcinoma, Squamous Cell/blood ; Carcinoma, Squamous Cell/chemically induced ; Carcinoma, Squamous Cell/radiotherapy ; Cell-Free Nucleic Acids/blood ; Circulating Tumor DNA/blood ; Cottontail rabbit papillomavirus ; Epithelial Cell Adhesion Molecule/blood ; Head and Neck Neoplasms/blood ; Head and Neck Neoplasms/chemically induced ; Head and Neck Neoplasms/radiotherapy ; Immunomagnetic Separation/methods ; Liquid Biopsy/methods ; Male ; Mouth Neoplasms/blood ; Mouth Neoplasms/chemically induced ; Mouth Neoplasms/radiotherapy ; Mouth Neoplasms/virology ; Nanoparticles ; Neoplasm Transplantation ; Open Reading Frames ; Rabbits ; Radiotherapy Dosage ; Tumor Burden
Chemical Substances	Biomarkers, Tumor ; Cell-Free Nucleic Acids ; Circulating Tumor DNA ; Epithelial Cell Adhesion Molecule
Language	English
Publishing date	2021-10-02
Publishing country	England
Document type	Journal Article
ISSN	1471-2407
ISSN (online)	1471-2407
DOI	10.1186/s12885-021-08791-8
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Article: Glycogen phosphorylase reactivity in the entorhinal complex in familiar and novel environments: evidence for labile glycogenolytic modules in the rat.

Walling, Susan G / Bromley, Kelley / Harley, Carolyn W

Journal of chemical neuroanatomy

2006 Volume 31, Issue 2, Page(s) 108–113

Abstract: Active and total glycogen phosphorylase were measured histochemically in the entorhinal complex of male Sprague-Dawley rats. Rats were sacrificed from their home cage, or after 5 min in a novel holeboard. Hemispheres from each group were paired, ... ...

Abstract	Active and total glycogen phosphorylase were measured histochemically in the entorhinal complex of male Sprague-Dawley rats. Rats were sacrificed from their home cage, or after 5 min in a novel holeboard. Hemispheres from each group were paired, sectioned and processed together. Glycogen phosphorylase reactivity highlighted entorhinal cortex in contrast to less densely stained perirhinal cortex or neocortex. The presubiculum, but not parasubiculum, was strongly reactive for glycogen phosphorylase. Within medial and lateral entorhinal cortex, modularity of active glycogen phosphorylase reactivity was apparent. In inner Layer I there were small ( approximately 50 microm) intense patches of active glycogen phosphorylase. In Layer III there were both small and larger ( approximately 200 microm), patches of active glycogen phosphorylase. Lamina dessicans was reactive. Layers V and VI were relatively unreactive. Exposure to a holeboard intensified the small patches of active glycogen phosphorylase in inner Layer I, while attenuating active glycogen phosphorylase reactivity in Layer III. Total glycogen phosphorylase was unaffected by exposure to the novel environment and exhibited a pattern of continuous dense reactivity suggesting enzyme reserves, particularly in superficial layers of entorhinal cortex. These patterns confirm earlier evidence that glycogenolytic demand in Layers I and III of rat entorhinal cortex is organized in a modular fashion and show that such demand can be modified by brief exposure to a novel holeboard.
MeSH term(s)	Animals ; Densitometry ; Entorhinal Cortex/metabolism ; Environment ; Glycogen Phosphorylase/metabolism ; Immunohistochemistry ; Isoenzymes/metabolism ; Male ; Rats ; Rats, Sprague-Dawley ; Stereotaxic Techniques ; Tissue Fixation
Chemical Substances	Isoenzymes ; Glycogen Phosphorylase (EC 2.4.1.-)
Language	English
Publishing date	2006-02
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	639443-7
ISSN	0891-0618
ISSN	0891-0618
DOI	10.1016/j.jchemneu.2005.09.004
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Article ; Online: First record of Euplectrus floryae (Hymenoptera

PATRÍCIA PAULA BELLON / KELLEN FAVERO / MARCELO TEIXEIRA TAVARES / HARLEY NONATO DE OLIVEIRA

Revista Colombiana de Entomología, Vol 39, Iss 1, Pp 166-

Eulophidae)parasitizing Erinnyis ello (Lepidoptera: Sphingidae) in Brazil

2013 Volume 167

Abstract: This is the first report of Euplectrus floryae (Hymenoptera: Eulophidae) in Brazil and also the first report of this species parasitizing larvae of Erinnyis ello (Lepidoptera: Sphingidae) on cassava. The occurrence of E. floryae on larvae of this pest on ...

Abstract	This is the first report of Euplectrus floryae (Hymenoptera: Eulophidae) in Brazil and also the first report of this species parasitizing larvae of Erinnyis ello (Lepidoptera: Sphingidae) on cassava. The occurrence of E. floryae on larvae of this pest on cassava opens up the possibility to integrate this natural enemy in biological control programs for cassava crops.
Keywords	Control biológico ; Yuca ; Parasitoide de larvas ; Zoology ; QL1-991 ; Science ; Q
Language	Spanish
Publishing date	2013-06-01T00:00:00Z
Publisher	Sociedad Colombiana de Entomología
Document type	Article ; Online
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