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  1. Article ; Online: Beta-Catenin-Mutated Hepatocellular Adenomas at Hepatobiliary Phase MRI: A Systematic Review and Meta-Analysis.

    Shen, Luyao / Altmayer, Stephan / Tse, Justin R

    Journal of magnetic resonance imaging : JMRI

    2024  

    Abstract: Background: Beta-catenin-mutated hepatocellular adenomas (β-HCAs) can appear iso- to hyperintense at the hepatobiliary phase (HBP) at magnetic resonance imaging (MRI). Given the relatively lower prevalence of β-HCAs, prior studies had limited power to ... ...

    Abstract Background: Beta-catenin-mutated hepatocellular adenomas (β-HCAs) can appear iso- to hyperintense at the hepatobiliary phase (HBP) at magnetic resonance imaging (MRI). Given the relatively lower prevalence of β-HCAs, prior studies had limited power to show statistically significant differences in the HBP signal intensity between different subtypes.
    Purpose: To assess the diagnostic performance of HBP MRI to discriminate β-HCA from other subtypes.
    Study type: Systemic review and meta-analysis.
    Population: Ten original studies were included, yielding 266 patients with 397 HCAs (9%, 36/397 β-HCAs and 91%, 361/397 non-β-HCAs).
    Field strength/sequence: 1.5 T and 3.0 T, HBP.
    Assessment: PubMed, Web of Science, and Embase databases were searched from January 1, 2000, to August 31, 2023, for all articles reporting HBP signal intensity in patients with histopathologically proven HCA subtypes. QUADAS-2 was used to assess risk of bias and concerns regarding applicability.
    Statistical tests: Univariate random-effects model was used to calculate pooled estimates. Heterogeneity estimates were assessed with I
    Results: HBP iso- to hyperintensity was associated with β-HCAs (pooled prevalence was 72.3% in β-HCAs and 6.3% in non-β-HCAs). Pooled sensitivity and specificity were 72.3% (95% confidence interval 54.1-85.3) and 93.7% (93.8-97.7), respectively. Specificity had substantial heterogeneity with I
    Data conclusion: Iso- to hyperintensity at HBP MRI may help to distinguish β-HCA subtype from other HCAs with high specificity. However, there was heterogeneity in the pooled estimates.
    Level of evidence: 3 TECHNICAL EFFICACY: Stage 2.
    Language English
    Publishing date 2024-02-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1146614-5
    ISSN 1522-2586 ; 1053-1807
    ISSN (online) 1522-2586
    ISSN 1053-1807
    DOI 10.1002/jmri.29279
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  2. Article: Traumatic sternal fractures.

    Hochhegger, Bruno / Altmayer, Stephan

    Radiologia brasileira

    2022  Volume 55, Issue 4, Page(s) IX

    Language English
    Publishing date 2022-08-02
    Publishing country Brazil
    Document type Editorial
    ZDB-ID 2078806-X
    ISSN 1678-7099 ; 0100-3984
    ISSN (online) 1678-7099
    ISSN 0100-3984
    DOI 10.1590/0100-3984.2022.55.4e3
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  3. Book ; Thesis: Über die mögliche Beteiligung des Polyomavirus BK an der Entstehung von Nierenkarzinomen

    Altmayer, Stephan

    PCR-Quantifizierung der viralen DNA in Karzinomnieren des Menschen und im Tumormodell der Wistarratte

    1997  

    Author's details vorgelegt von Stephan Altmayer
    Language German
    Size II, 65 Bl. : Ill., graph. Darst.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Hannover, Med. Hochsch., Diss., 1998
    HBZ-ID HT009132444
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    98 E 2622 order for loan Magazin

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  4. Article ; Online: Letter by Simonato and Altmayer Regarding Article, "Dog Ownership and Survival: A Systematic Review and Meta-Analysis".

    Simonato, Matheus / Altmayer, Stephan

    Circulation. Cardiovascular quality and outcomes

    2020  Volume 13, Issue 10, Page(s) e006368

    MeSH term(s) Animals ; Dogs ; Human-Animal Bond ; Ownership ; Pets
    Language English
    Publishing date 2020-10-20
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2483197-9
    ISSN 1941-7705 ; 1941-7713
    ISSN (online) 1941-7705
    ISSN 1941-7713
    DOI 10.1161/CIRCOUTCOMES.119.006368
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  5. Article ; Online: Appropriateness and imaging outcomes of ultrasound, CT, and MR in the emergency department: a retrospective analysis from an urban academic center.

    Francisco, Martina Zaguini / Altmayer, Stephan / Carlesso, Lucas / Zanon, Matheus / Eymael, Thales / Lima, Jose Eduardo / Watte, Guilherme / Hochhegger, Bruno

    Emergency radiology

    2024  

    Abstract: Purpose: To evaluate the appropriateness and outcomes of ultrasound (US), computed tomography (CT), and magnetic resonance (MR) orders in the ED.: Methods: We retrospectively reviewed consecutive US, CT, and MR orders for adult ED patients at a ... ...

    Abstract Purpose: To evaluate the appropriateness and outcomes of ultrasound (US), computed tomography (CT), and magnetic resonance (MR) orders in the ED.
    Methods: We retrospectively reviewed consecutive US, CT, and MR orders for adult ED patients at a tertiary care urban academic center from January to March 2019. The American College of Radiology Appropriateness Criteria (ACRAC) guidelines were primarily used to classify imaging orders as "appropriate" or "inappropriate". Two radiologists in consensus judged specific clinical scenarios that were unavailable in the ACRAC. Final imaging reports were compared with the initial clinical suspicion for imaging and categorized into "normal", "compatible with initial diagnosis", "alternative diagnosis", or "inconclusive". The sample was powered to show a prevalence of inappropriate orders of 30% with a margin of error of 5%.
    Results: The rate of inappropriate orders was 59.4% for US, 29.1% for CT, and 33.3% for MR. The most commonly imaged systems for each modality were neuro (130/330) and gastrointestinal (95/330) for CT, genitourinary (132/330) and gastrointestinal (121/330) for US, neuro (273/330) and gastrointestinal (37/330) for MR. Compared to inappropriately ordered tests, the final reports of appropriate orders were nearly three times more likely to demonstrate findings compatible with the initial diagnosis for all modalities: US (45.5 vs. 14.3%, p < 0.001), CT (46.6 vs. 14.6%, p < 0.001), and MR (56.3 vs. 21.8%, p < 0.001). Inappropriate orders were more likely to show no abnormalities compared to appropriate orders: US (65.8 vs. 38.8%, p < 0.001), CT (62.5 vs. 34.2%, p < 0.001), and MR (61.8 vs. 38.7%, p < 0.001).
    Conclusion: The prevalence of inappropriate imaging orders in the ED was 59.4% for US, 29.1% for CT, and 33.3% for MR. Appropriately ordered imaging was three times more likely to yield findings compatible with the initial diagnosis across all modalities.
    Language English
    Publishing date 2024-04-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1425144-9
    ISSN 1438-1435 ; 1070-3004
    ISSN (online) 1438-1435
    ISSN 1070-3004
    DOI 10.1007/s10140-024-02226-0
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  6. Article ; Online: Correction to: Split scar sign to predict complete response in rectal cancer after neoadjuvant chemoradiotherapy: systematic review and meta-analysis.

    Torri, Giovanni Brondani / Wiethan, Camila Piovesan / Langer, Felipe Welter / de Oliveira, Guilherme Strieder / Meirelles, Alice Villa Bella / Horvat, Natally / Tse, Justin Ruey / Dias, Adriano Basso / Altmayer, Stephan

    European radiology

    2024  

    Language English
    Publishing date 2024-01-19
    Publishing country Germany
    Document type Published Erratum
    ZDB-ID 1085366-2
    ISSN 1432-1084 ; 0938-7994 ; 1613-3749
    ISSN (online) 1432-1084
    ISSN 0938-7994 ; 1613-3749
    DOI 10.1007/s00330-023-10576-5
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  7. Article ; Online: Left Ventricular Dysfunction in Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC): Can We Separate ARVC From Other Arrhythmogenic Cardiomyopathies?

    Altmayer, Stephan / Nazarian, Saman / Han, Yuchi

    Journal of the American Heart Association

    2020  Volume 9, Issue 23, Page(s) e018866

    Abstract: Arrhythmogenic right ventricular cardiomyopathy was first described as a right ventricular disease that is an important cause of death in young adults. However, with the advent of advanced imaging, arrhythmogenic right ventricular cardiomyopathy has been ...

    Abstract Arrhythmogenic right ventricular cardiomyopathy was first described as a right ventricular disease that is an important cause of death in young adults. However, with the advent of advanced imaging, arrhythmogenic right ventricular cardiomyopathy has been found to commonly have biventricular involvement, and a small portion of patients have left ventricular-dominant forms. On the other hand, a number of primarily left ventricular disease such as sarcoid and myocarditis can be arrhythmogenic and have right ventricular involvement. A few recent publications on arrhythmogenic right ventricular cardiomyopathy cohorts have average left ventricular functions that are comparable to sarcoid or myocarditis cohorts. We review the current literature and compare these cohorts of patients, and call for left ventricular functional criteria for arrhythmogenic right ventricular cardiomyopathy as inherited arrhythmogenic cardiomyopathy.
    MeSH term(s) Arrhythmogenic Right Ventricular Dysplasia/complications ; Arrhythmogenic Right Ventricular Dysplasia/diagnosis ; Arrhythmogenic Right Ventricular Dysplasia/physiopathology ; Diagnosis, Differential ; Humans ; Stroke Volume ; Ventricular Dysfunction, Left/complications ; Ventricular Dysfunction, Left/diagnosis ; Ventricular Dysfunction, Left/physiopathology
    Language English
    Publishing date 2020-11-21
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2653953-6
    ISSN 2047-9980 ; 2047-9980
    ISSN (online) 2047-9980
    ISSN 2047-9980
    DOI 10.1161/JAHA.120.018866
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  8. Article ; Online: Artificial Intelligence for Cardiothoracic Imaging: Overview of Current and Emerging Applications.

    Hochhegger, Bruno / Pasini, Romulo / Roncally Carvalho, Alysson / Rodrigues, Rosana / Altmayer, Stephan / Kayat Bittencourt, Leonardo / Marchiori, Edson / Forghani, Reza

    Seminars in roentgenology

    2023  Volume 58, Issue 2, Page(s) 184–195

    Abstract: Artificial intelligence algorithms can learn by assimilating information from large datasets in order to decipher complex associations, identify previously undiscovered pathophysiological states, and construct prediction models. There has been tremendous ...

    Abstract Artificial intelligence algorithms can learn by assimilating information from large datasets in order to decipher complex associations, identify previously undiscovered pathophysiological states, and construct prediction models. There has been tremendous interest and increased incorporation of artificial intelligence into various industries, including healthcare. As a result, there has been an exponential rise in the number of research articles and industry participants producing models intended for a variety of applications in medical imaging, which can be challenging to navigate for radiologists. In thoracic imaging, multiple applications are being evaluated for chest radiography and computed tomography and include applications for lung nodule evaluation and cancer imaging, quantifying diffuse lung disorders, and cardiac imaging, to name a few. This review aims to provide an overview of current clinical AI models, focusing on the most common clinical applications of AI in cardiothoracic imaging.
    MeSH term(s) Humans ; Artificial Intelligence ; Algorithms ; Tomography, X-Ray Computed ; Radiologists
    Language English
    Publishing date 2023-03-05
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 80310-8
    ISSN 1558-4658 ; 0037-198X
    ISSN (online) 1558-4658
    ISSN 0037-198X
    DOI 10.1053/j.ro.2023.02.001
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  9. Article ; Online: Imaging Findings in Aspergillosis: From Head to Toe.

    Sousa, Célia / Pasini, Romulo Antonio / Pasqualotto, Alessandro / Marchiori, Edson / Altmayer, Stephan / Irion, Klaus / Mançano, Alexandre / Hochhegger, Bruno

    Mycopathologia

    2023  Volume 188, Issue 5, Page(s) 623–641

    Abstract: Aspergillosis is a mycotic infection induced by airborne fungi that are ubiquitous. Inhalation of Aspergillus conidia results in transmission through the respiratory tract. The clinical presentation is dependent on organism and host specifics, with ... ...

    Abstract Aspergillosis is a mycotic infection induced by airborne fungi that are ubiquitous. Inhalation of Aspergillus conidia results in transmission through the respiratory tract. The clinical presentation is dependent on organism and host specifics, with immunodeficiency, allergies, and preexisting pulmonary disease constituting the most important risk factors. In recent decades, the incidence of fungal infections has increased dramatically, due in part to the increased number of transplants and the pervasive use of chemotherapy and immunosuppressive drugs. The spectrum of clinical manifestations can range from an asymptomatic or mild infection to a swiftly progressive, life-threatening illness. Additionally, invasive infections can migrate to extrapulmonary sites, causing infections in distant organs. Recognition and familiarity with the various radiological findings in the appropriate clinical context are essential for patient management and the prompt initiation of life-saving treatment. We discuss the radiological characteristics of chronic and invasive pulmonary aspergillosis, as well as some of the typically unexpected extrapulmonary manifestations of disseminated disease.
    Language English
    Publishing date 2023-06-28
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 391081-7
    ISSN 1573-0832 ; 0369-299X ; 0301-486X ; 0027-5530
    ISSN (online) 1573-0832
    ISSN 0369-299X ; 0301-486X ; 0027-5530
    DOI 10.1007/s11046-023-00766-6
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  10. Article ; Online: Switching from sildenafil to riociguat in patients with persistent or inoperable chronic thromboembolic pulmonary hypertension.

    Watte, Guilherme / Mello, Marcelo / Altmayer, Stephan / Hochhegger, Bruno

    International journal of cardiology

    2019  Volume 277, Page(s) 239

    MeSH term(s) Hemodynamics ; Humans ; Hypertension, Pulmonary ; Pyrazoles ; Pyrimidines ; Sildenafil Citrate
    Chemical Substances Pyrazoles ; Pyrimidines ; Sildenafil Citrate (BW9B0ZE037) ; riociguat (RU3FE2Y4XI)
    Language English
    Publishing date 2019-01-17
    Publishing country Netherlands
    Document type Letter ; Comment
    ZDB-ID 779519-1
    ISSN 1874-1754 ; 0167-5273
    ISSN (online) 1874-1754
    ISSN 0167-5273
    DOI 10.1016/j.ijcard.2018.09.076
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