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  1. Article ; Online: Does glucosamine/chondroitin sulfate have a long-term effect on the progression of structural changes in knee osteoarthritis? Comment on the article by Raynauld et al.

    Fernández-Cuadros, Marcos Edgar

    Arthritis care & research

    2017  Volume 70, Issue 1, Page(s) 167

    MeSH term(s) Chondroitin Sulfates ; Diagnostic Tests, Routine ; Disease Progression ; Glucosamine ; Humans ; Osteoarthritis, Knee
    Chemical Substances Chondroitin Sulfates (9007-28-7) ; Glucosamine (N08U5BOQ1K)
    Language English
    Publishing date 2017-12-08
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 645059-3
    ISSN 2151-4658 ; 0893-7524 ; 2151-464X
    ISSN (online) 2151-4658
    ISSN 0893-7524 ; 2151-464X
    DOI 10.1002/acr.23313
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Uso de ozonoterapia rectal en paciente anciana con neumonía grave por COVID-19.

    Peña-Lora, Daiana Yulissa / Albaladejo-Florín, María Jesús / Fernández-Cuadros, Marcos Edgar

    Revista espanola de geriatria y gerontologia

    2020  Volume 55, Issue 6, Page(s) 362–364

    Title translation Usefulness of rectal ozonetherapy in a geriatric patient with severe COVID-19 pneumonia.
    MeSH term(s) Administration, Rectal ; Aged, 80 and over ; COVID-19/blood ; COVID-19/diagnosis ; COVID-19/diagnostic imaging ; COVID-19/therapy ; COVID-19 Testing/methods ; Female ; Humans ; Ozone/administration & dosage ; SARS-CoV-2
    Chemical Substances Ozone (66H7ZZK23N)
    Keywords covid19
    Language Spanish
    Publishing date 2020-08-17
    Publishing country Spain
    Document type Case Reports
    ZDB-ID 605609-x
    ISSN 1578-1747 ; 0211-139X
    ISSN (online) 1578-1747
    ISSN 0211-139X
    DOI 10.1016/j.regg.2020.07.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Uso de ozonoterapia rectal en paciente anciana con neumonía grave por COVID-19

    Peña-Lora, Daiana Yulissa / Albaladejo-Florín, María Jesús / Fernández-Cuadros, Marcos Edgar

    Revista Española de Geriatría y Gerontología ; ISSN 0211-139X

    2020  

    Keywords Medicine (miscellaneous) ; Ageing ; Geriatrics and Gerontology ; covid19
    Language Spanish
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    DOI 10.1016/j.regg.2020.07.005
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Ozone (O3) and SARS-CoV-2: Physiological Bases and Their Therapeutic Possibilities According to COVID-19 Evolutionary Stage.

    Fernández-Cuadros, Marcos Edgar / Albaladejo-Florín, María Jesús / Peña-Lora, Daiana / Álava-Rabasa, Sandra / Pérez-Moro, Olga Susana

    SN comprehensive clinical medicine

    2020  Volume 2, Issue 8, Page(s) 1094–1102

    Abstract: To date, there is no definitive treatment for the new SARS-CoV-2 pandemic. Three evolutionary stages in SARS-CoV-2 infection are recognized (early infection, pulmonary phase, and systemic hyper inflammation), with characteristic clinical signs and ... ...

    Abstract To date, there is no definitive treatment for the new SARS-CoV-2 pandemic. Three evolutionary stages in SARS-CoV-2 infection are recognized (early infection, pulmonary phase, and systemic hyper inflammation), with characteristic clinical signs and symptoms. There are 80 international experimental trials underway seeking effective treatment for the COVID-19 pandemic. Of these, there are only three that consider ozone therapy (major auto hemotherapy) as an alternative option. There is no study that evaluates rectal ozone insufflation, despite being a safe, cheap, risk-free technique. That technique is a systemic route of ozone administration (95-96%) and that could be extrapolated to the use of SARS-CoV-2, given the excellent results observed in the management of Ebola. Ozone has four proven biological properties that could allow its use as an alternative therapy in the different phases of SARS-CoV-2 infection. Ozone could inactivate the virus by direct (O3) or indirect oxidation (ROS and LOPs) and could stimulate the cellular and humoral immune systems, being useful in the early COVID-19 infection phase (stages 1 and 2a). Ozone improves gas exchange, reduces inflammation, and modulates the antioxidant system, so it would be useful in the hyper inflammation or "cytokine storm" phase, and in the hypoxemia and/or multi-organ failure phase (stage 2b and stage 3). Given the current pandemic, it is urgent to carry out an experimental study that confirms or rules out the biological properties of ozone and thus allows it to be an alternative or compassionate therapy for the effective management of SARS-Cov-2 infection. The Ethical Committee at our Hospital has authorized the use of this technique for compassionate management of SARS-CoV-2 infection, considering the four biological Ozone properties exposed previously.
    Keywords covid19
    Language English
    Publishing date 2020-07-07
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2947211-8
    ISSN 2523-8973 ; 2523-8973
    ISSN (online) 2523-8973
    ISSN 2523-8973
    DOI 10.1007/s42399-020-00328-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Uso de ozonoterapia rectal en paciente anciana con neumonía grave por COVID-19./ [Usefulness of rectal ozonetherapy in a geriatric patient with severe COVID-19 pneumonia]

    Peña-Lora, Daiana Yulissa / Albaladejo-Florín, María Jesús / Fernández-Cuadros, Marcos Edgar

    Rev. esp. geriatr. gerontol. (Ed. impr.)

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #716931
    Database COVID19

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  6. Article: Bilateral Levofloxacin-Induced Achilles Tendon Rupture: An Uncommon Case Report and Review of the Literature.

    Fernández-Cuadros, Marcos Edgar / Casique-Bocanegra, Luz Otilia / Albaladejo-Florín, María Jesús / Gómez-Dueñas, Sheila / Ramos-Gonzalez, Carmen / Pérez-Moro, Olga Susana

    Clinical medicine insights. Arthritis and musculoskeletal disorders

    2019  Volume 12, Page(s) 1179544119835222

    Abstract: Since the introduction of Fluoroquinolones (FQ) in 1960s, these antibiotics have been used in airway and urinary tract infections, due to absorption, biodisponibility, posology and long half-life time properties. However, several reports state that FQ ... ...

    Abstract Since the introduction of Fluoroquinolones (FQ) in 1960s, these antibiotics have been used in airway and urinary tract infections, due to absorption, biodisponibility, posology and long half-life time properties. However, several reports state that FQ can cause tendinopathy and rupture. These adverse effects can occur within hours after initial treatment to up to 6 months after withdrawal. FQ-induced tendinopathy was first reported in 1983; since then more than 100 cases have been published. FQ usage can lead to complete tendon rupture and no more than 8 to 15 cases are reported worldwide. Most of rupture cases have been associated to corticoid use and rheumatic, vascular or renal disease. The purpose of this case report is to present the challenging diagnosis of a bilateral rupture of Achilles tendon in an old patient, because of the uncommon of the presentation and to review the current literature on such a debilitating condition.
    Language English
    Publishing date 2019-03-05
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2590933-2
    ISSN 1179-5441
    ISSN 1179-5441
    DOI 10.1177/1179544119835222
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Usefulness of rectal ozonetherapy in a geriatric patient with severe COVID-19 pneumonia

    Pena-Lora, Daiana Yulissa / Albaladejo-Florin, Maria Jesus / Fernandez-Cuadros, Marcos Edgar

    Revista espanola de geriatria y gerontologia

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #752923
    Database COVID19

    Kategorien

  8. Article ; Online: Ozone (O3) and SARS-CoV-2

    Fernández-Cuadros, Marcos Edgar / Albaladejo-Florín, María Jesús / Peña-Lora, Daiana / Álava-Rabasa, Sandra / Pérez-Moro, Olga Susana

    SN Comprehensive Clinical Medicine

    Physiological Bases and Their Therapeutic Possibilities According to COVID-19 Evolutionary Stage

    2020  Volume 2, Issue 8, Page(s) 1094–1102

    Keywords covid19
    Language English
    Publisher Springer Science and Business Media LLC
    Publishing country us
    Document type Article ; Online
    ZDB-ID 2947211-8
    ISSN 2523-8973
    ISSN 2523-8973
    DOI 10.1007/s42399-020-00328-7
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article: Ozone (O3) and SARS-CoV-2: Physiological Bases and Their Therapeutic Possibilities According to COVID-19 Evolutionary Stage

    Fernández-Cuadros, Marcos Edgar / Albaladejo-Florín, María Jesús / Peña-Lora, Daiana / Álava-Rabasa, Sandra / Pérez-Moro, Olga Susana

    SN Compr Clin Med

    Abstract: To date, there is no definitive treatment for the new SARS-CoV-2 pandemic. Three evolutionary stages in SARS-CoV-2 infection are recognized (early infection, pulmonary phase, and systemic hyper inflammation), with characteristic clinical signs and ... ...

    Abstract To date, there is no definitive treatment for the new SARS-CoV-2 pandemic. Three evolutionary stages in SARS-CoV-2 infection are recognized (early infection, pulmonary phase, and systemic hyper inflammation), with characteristic clinical signs and symptoms. There are 80 international experimental trials underway seeking effective treatment for the COVID-19 pandemic. Of these, there are only three that consider ozone therapy (major auto hemotherapy) as an alternative option. There is no study that evaluates rectal ozone insufflation, despite being a safe, cheap, risk-free technique. That technique is a systemic route of ozone administration (95-96%) and that could be extrapolated to the use of SARS-CoV-2, given the excellent results observed in the management of Ebola. Ozone has four proven biological properties that could allow its use as an alternative therapy in the different phases of SARS-CoV-2 infection. Ozone could inactivate the virus by direct (O3) or indirect oxidation (ROS and LOPs) and could stimulate the cellular and humoral immune systems, being useful in the early COVID-19 infection phase (stages 1 and 2a). Ozone improves gas exchange, reduces inflammation, and modulates the antioxidant system, so it would be useful in the hyper inflammation or "cytokine storm" phase, and in the hypoxemia and/or multi-organ failure phase (stage 2b and stage 3). Given the current pandemic, it is urgent to carry out an experimental study that confirms or rules out the biological properties of ozone and thus allows it to be an alternative or compassionate therapy for the effective management of SARS-Cov-2 infection. The Ethical Committee at our Hospital has authorized the use of this technique for compassionate management of SARS-CoV-2 infection, considering the four biological Ozone properties exposed previously.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #649656
    Database COVID19

    Kategorien

  10. Article ; Online: Effect of Rectal Ozone (O

    Fernández-Cuadros, Marcos Edgar / Albaladejo-Florín, María Jesús / Álava-Rabasa, Sandra / Usandizaga-Elio, Isabel / Martinez-Quintanilla Jimenez, Dolores / Peña-Lora, Daiana / Neira-Borrajo, Inmaculada / López-Muñoz, María Jesús / Rodríguez-de-Cía, Javier / Pérez-Moro, Olga Susana

    SN comprehensive clinical medicine

    2020  Volume 2, Issue 9, Page(s) 1328–1336

    Abstract: The aim of this study is to evaluate the effectiveness of rectal ozone ( ... ...

    Abstract The aim of this study is to evaluate the effectiveness of rectal ozone (O
    Keywords covid19
    Language English
    Publishing date 2020-08-03
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2947211-8
    ISSN 2523-8973 ; 2523-8973
    ISSN (online) 2523-8973
    ISSN 2523-8973
    DOI 10.1007/s42399-020-00374-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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