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  1. Article ; Online: COVID-19: find the right questions to be answered.

    Giacomelli, Andrea / Antinori, Spinello / Gori, Andrea / Cozzi-Lepri, Alessandro

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

    2024  

    Language English
    Publishing date 2024-02-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1099781-7
    ISSN 1537-6591 ; 1058-4838
    ISSN (online) 1537-6591
    ISSN 1058-4838
    DOI 10.1093/cid/ciae078
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    Zs.A 1505: Show issues Location:
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  2. Article ; Online: The WHO fungal priority pathogens list: a crucial reappraisal to review the prioritisation.

    Casalini, Giacomo / Giacomelli, Andrea / Antinori, Spinello

    The Lancet. Microbe

    2024  

    Abstract: In October, 2022, WHO published the first fungal priority pathogen list, which categorised 19 fungal entities into three priority groups (critical, high, and medium), for prioritisation of research efforts. The final ranking was determined via multiple ... ...

    Abstract In October, 2022, WHO published the first fungal priority pathogen list, which categorised 19 fungal entities into three priority groups (critical, high, and medium), for prioritisation of research efforts. The final ranking was determined via multiple criteria decision analysis, considering both research and development needs and perceived public health importance. In this Personal View, we discuss the positioning of the fungal pathogens, namely, Mucorales, Candida spp, Histoplasma spp, Coccidioides and Paracoccidioides spp, Fusarium spp, eumycetoma causative agents, Talaromyces marneffei, and Pneumocystis jirovecii, while expressing concerns about potential disparities between the WHO fungal priority pathogen list ranking and the actual disease burden associated with these pathogens. Finally, we propose a revised prioritisation list that also considers the regional disparities in the burden of fungal diseases.
    Language English
    Publishing date 2024-04-09
    Publishing country England
    Document type Journal Article ; Review
    ISSN 2666-5247
    ISSN (online) 2666-5247
    DOI 10.1016/S2666-5247(24)00042-9
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  3. Article ; Online: Drug Shortages Highlight the Need for Expanded Treatment Options for Syphilis.

    Lazzarin, Samuel / Giacomelli, Andrea / Moschese, Davide / Antinori, Spinello / Gervasoni, Cristina

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

    2023  Volume 77, Issue 9, Page(s) 1356

    MeSH term(s) Humans ; Pregnancy ; Female ; Syphilis/drug therapy ; Syphilis, Congenital ; Pregnancy Complications, Infectious/drug therapy
    Language English
    Publishing date 2023-06-29
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1099781-7
    ISSN 1537-6591 ; 1058-4838
    ISSN (online) 1537-6591
    ISSN 1058-4838
    DOI 10.1093/cid/ciad396
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  4. Article ; Online: A HIV-positive subject with dermatomal and generalized vesicular skin lesions.

    Poloni, Andrea / Cossu, Maria Vittoria / Antinori, Spinello

    European journal of internal medicine

    2022  Volume 102, Page(s) 112–113

    MeSH term(s) HIV Infections/drug therapy ; Herpes Zoster ; Humans ; Skin Diseases/diagnosis
    Language English
    Publishing date 2022-05-14
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1038679-8
    ISSN 1879-0828 ; 0953-6205
    ISSN (online) 1879-0828
    ISSN 0953-6205
    DOI 10.1016/j.ejim.2022.05.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Bacterial Coinfections in COVID-19 Patients without a Positive Microbiologic Result: a Word of Caution.

    Casalini, Giacomo / Pozza, Giacomo / Giacomelli, Andrea / Antinori, Spinello

    Antimicrobial agents and chemotherapy

    2022  Volume 66, Issue 3, Page(s) e0229621

    MeSH term(s) Anti-Bacterial Agents/therapeutic use ; Bacteria ; COVID-19 ; Coinfection/drug therapy ; Humans
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2022-01-03
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 217602-6
    ISSN 1098-6596 ; 0066-4804
    ISSN (online) 1098-6596
    ISSN 0066-4804
    DOI 10.1128/aac.02296-21
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    Zs.A 809: Show issues Location:
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    Einzelsignatur: Show issues

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  6. Article ; Online: Laryngeal Leishmaniasis: A Neglected, Emerging Disease in Northern Italy.

    Lazzeroni, Matteo / Reato, Serena / Antinori, Spinello / Milazzo, Laura / Pignataro, Lorenzo / Cantarella, Giovanna

    Journal of voice : official journal of the Voice Foundation

    2024  

    Abstract: Leishmaniasis represents an emerging public health issue in Mediterranean countries. The incidence of this condition has progressively risen in Northern Italy due to the growing number of immunocompromised people and probably due to climate changes. We ... ...

    Abstract Leishmaniasis represents an emerging public health issue in Mediterranean countries. The incidence of this condition has progressively risen in Northern Italy due to the growing number of immunocompromised people and probably due to climate changes. We hereby describe a case of relapsing laryngeal leishmaniasis in a female immunocompetent patient, presenting as aspecific chronic laryngitis. She was affected by severe asthma treated by inhaled steroid therapy, likely responsible for the parasite's diffusion through a locus minori resistentiae. The aspecific clinical presentation led to a delayed diagnosis and the lack of guidelines for the treatment caused multiple relapses. Biopsies of laryngeal lesions in the follow-up were performed by operative flexible videolaryngoscopy, thus avoiding general anesthesia and reducing associated healthcare costs. The aim of this report is to underline the diagnostic and therapeutic challenges that patients with this condition face and to present what is, to the best of our knowledge, the first application of prophylactic aerosolized pentamidine for relapsing laryngeal leishmaniasis.
    Language English
    Publishing date 2024-04-23
    Publishing country United States
    Document type Case Reports
    ZDB-ID 17459-2
    ISSN 1873-4588 ; 1557-8658 ; 0892-1997
    ISSN (online) 1873-4588 ; 1557-8658
    ISSN 0892-1997
    DOI 10.1016/j.jvoice.2024.04.006
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  7. Article ; Online: Chagas disease in Italy: an update of epidemiological studies.

    Antinori, Spinello / Giacomelli, Andrea / Sabaini, Federico / Casalini, Giacomo / Ridolfo, Anna Lisa

    Le infezioni in medicina

    2023  Volume 31, Issue 3, Page(s) 421–424

    Language English
    Publishing date 2023-09-01
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2041081-5
    ISSN 2532-8689 ; 1124-9390
    ISSN (online) 2532-8689
    ISSN 1124-9390
    DOI 10.53854/liim-3103-18
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  8. Article ; Online: Endemic mycoses: geographical distribution is still a work in progress.

    Antinori, Spinello / Ridolfo, Anna Lisa / Casalini, Giacomo / Giacomelli, Andrea

    The Lancet. Infectious diseases

    2022  Volume 22, Issue 4, Page(s) 451

    MeSH term(s) Histoplasmosis/epidemiology ; Humans ; Mycoses/epidemiology
    Language English
    Publishing date 2022-01-28
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2061641-7
    ISSN 1474-4457 ; 1473-3099
    ISSN (online) 1474-4457
    ISSN 1473-3099
    DOI 10.1016/S1473-3099(22)00131-1
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    Zs.A 5743: Show issues Location:
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  9. Article ; Online: Evolution of the SARS-CoV-2 epidemic: From genomic surveillance to new health needs.

    Giacomelli, Andrea / Ridolfo, Anna Lisa / Oreni, Letizia / Rizzardini, Giuliano / Antinori, Spinello

    European journal of internal medicine

    2023  Volume 110, Page(s) 99–100

    MeSH term(s) Humans ; SARS-CoV-2 ; COVID-19 ; Genomics ; Disease Outbreaks
    Language English
    Publishing date 2023-02-09
    Publishing country Netherlands
    Document type Letter ; Comment
    ZDB-ID 1038679-8
    ISSN 1879-0828 ; 0953-6205
    ISSN (online) 1879-0828
    ISSN 0953-6205
    DOI 10.1016/j.ejim.2023.02.005
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  10. Article ; Online: Update on Mpox: a brief narrative review.

    Antinori, Spinello / Casalini, Giacomo / Giacomelli, Andrea / Rodriguez-Morales, Alfonso J

    Le infezioni in medicina

    2023  Volume 31, Issue 3, Page(s) 269–276

    Abstract: Mpox (formerly Monkeypox), a neglected tropical disease once confined to Central and West Africa, emerged as a global epidemic outbreak in May, 2022 with 87,529 cases reported as of May, 23, 2023. It predominantly affected men (96.2%) who have sex with ... ...

    Abstract Mpox (formerly Monkeypox), a neglected tropical disease once confined to Central and West Africa, emerged as a global epidemic outbreak in May, 2022 with 87,529 cases reported as of May, 23, 2023. It predominantly affected men (96.2%) who have sex with men (84-100%), although other transmission routes have been reported, including occupational exposure and vertical transmission. Concomitant HIV infection has been recorded in 21-46.9% and pre-exposure prophylaxis against HIV infection has been reported in 11-57% of published cases. The current outbreak clinical presentation differs from endemic cases with prodromal symptoms that could be absent: the number of lesions is generally low, with skin lesions predominantly localised in the ano-genital areas and frequent lesions present in different stages of progression (i.e., asynchronous). Asymptomatic Mpox infection can occur in 1.8-6.5% of at-risk subjects. People living with HIV with severe immunodeficiency (less than 100 CD4+ lymphocytes per microliter) are at risk of more severe clinical manifestations and death. According to a systematic review and meta-analysis, the hospitalisation rate is around 6% and the observed case-fatality rate is less than 0.1%. Tecovirimat is the drug of choice for treating severe cases although there is no evidence of efficacy from randomised controlled trials. Immunization with a live non-replicating vaccine (JYNNEOS) effectively reduces the disease's incidence.
    Language English
    Publishing date 2023-09-01
    Publishing country Italy
    Document type Journal Article ; Review
    ZDB-ID 2041081-5
    ISSN 2532-8689 ; 1124-9390
    ISSN (online) 2532-8689
    ISSN 1124-9390
    DOI 10.53854/liim-3103-1
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