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Article ; Online: Création et évaluation d’un MOOC sur le syndrome confusionnel en oncogériatrie.

Antoine, Valery / Nicolas, Charlotte / Albarède, Julie / Azria, David / Cristol, Laurence / Jeandel, Claude / Ferreira, Ernestine / Morel, Charlotte / Mourey, Loïc / Balardy, Laurent

Bulletin du cancer

2021 Volume 108, Issue 12, Page(s) 1101–1111

Abstract: Introduction: Among the themes to be addressed by a Massive Open Online Course (MOOC) on geriatric oncology, one of the priorities was delirium, due to its frequency, complications and difficulties encountered by healthcare professionals in diagnosing ... ...

Title translation	Development and assessment of a MOOC about delirium in geriatric oncology.
Abstract	Introduction: Among the themes to be addressed by a Massive Open Online Course (MOOC) on geriatric oncology, one of the priorities was delirium, due to its frequency, complications and difficulties encountered by healthcare professionals in diagnosing and managing delirium. Our study aims to evaluate professional practices in the area of education, regarding the evaluation of the content of a MOOC module about delirium syndrome in geriatric oncology. Methods: We created a multidisciplinary group to define the scientific content, the pedagogical objectives, the scriptwriting and the development of a training module. The quality of instructional design was then evaluated according to eleven MOOC design principles to promote learning. Participants were studied. Results: Seven of the eleven criteria for evaluating pedagogical quality were documented. Among the 1020 participants, 455 (44.6%) completed the final test concerning delirium: 417 (40.8%) passed the final test; 406 documented their profession and the region of France where they worked: 146 (32%) nurses (confirming the participation of the targeted audience), 103 (22.6%) doctors/pharmacists (illustrating the multi-professional interest of the thematic), with a wide distribution of the participants over the national territory. Discussion: The multidisciplinary team's investment in developing these teaching materials strengthened the group's cohesion and valuated its professional skills. All teaching resources developed for access via the internet must be accompanied by an evaluation of the quality of the scientific content, objectives and teaching methods, before being able to appreciate its use in the field and assess its real impact on the participants' learning and practice.
MeSH term(s)	Aged ; Clinical Competence/statistics & numerical data ; Curriculum ; Delirium/diagnosis ; Delirium/etiology ; Delirium/therapy ; Education, Distance/organization & administration ; Educational Measurement/statistics & numerical data ; Female ; France ; Geriatrics/education ; Humans ; Male ; Medical Oncology/education ; Nurses/statistics & numerical data ; Pharmacists/statistics & numerical data ; Physicians/statistics & numerical data ; Program Development/methods ; Risk Factors ; Students, Health Occupations/statistics & numerical data ; Syndrome ; Teaching
Language	French
Publishing date	2021-10-21
Publishing country	France
Document type	Journal Article
ZDB-ID	213270-9
ISSN	1769-6917 ; 0007-4551
ISSN (online)	1769-6917
ISSN	0007-4551
DOI	10.1016/j.bulcan.2021.05.014
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Article: L’adhésion des urologues aux recommandations du comité de cancérologie de l’association Française d’urologie (CCAFU) dans le bilan d’imagerie du cancer localisé de la prostate.

Trétarre, B / Trouche-Sabatier, S-G / Foucan, A-S / Abdo, N / Poinas, G / Rébillard, X / Azria, D / Iborra, F

Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie

2022 Volume 32, Issue 16, Page(s) 1446–1454

Abstract: Objectives: The literature review shows a low adhesion of urologists to the recommendations of learned societies in the imaging work-up of localized prostate cancer (CaP), especially for low and intermediate risks of the D'Amico classification. We ... ...

Title translation	Adhesion of urologists to the recommendations of the French Urological Association Cancer Committee (CCAFU) in the imaging work-up of localized prostate cancer.
Abstract	Objectives: The literature review shows a low adhesion of urologists to the recommendations of learned societies in the imaging work-up of localized prostate cancer (CaP), especially for low and intermediate risks of the D'Amico classification. We analyzed the adhesion of urologists in the Hérault region (France) to the CCAFU 2016/2018, 2018/2020 recommendations. Material and methods: From the Hérault Onco Urology Registry (RHESOU) database, we identified localized CaP diagnosed between 01/01/2017 and 31/12/2019, and then classified them into 3 distinct risk groups according to the D'Amico classification. We compared the imaging workup performed by each patient to the CCAFU 2016/2018, 2018/2020 recommendations, according to the risk group. Results: Of the 2,049 localized CaPs included in our study, 591 belonged to the low-risk group, 1059 to the intermediate-risk group, and 399 to the high-risk group. In the low-risk group 45.2% of the cases did not follow the CCAFU 2016/2018, 2018/2020 recommendations in the imaging workup, 77.3% in the intermediate-risk group and 80.9% in the high-risk group. For our entire study, 1,408 patients (68.7%) had an imaging workup that did not follow the CCAFU recommendations. Conclusion: Our results show a low adhesion of urologists to the CCAFU recommendations in the imaging assessment of localized CaP. The causes of this non-adhesion are multifactorial and difficult to analyze.
MeSH term(s)	Humans ; Male ; France ; Prostatic Neoplasms/diagnostic imaging ; Urologic Neoplasms/diagnosis ; Urologists ; Urology
Language	French
Publishing date	2022-11-04
Publishing country	France
Document type	English Abstract ; Journal Article ; Review
ZDB-ID	1186190-3
ISSN	1166-7087
ISSN	1166-7087
DOI	10.1016/j.purol.2022.09.021
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Article ; Online: Interventions non médicamenteuses et cancer du sein : quel bénéfice en complément d’une radiothérapie ?

Lognos, Béatrice / Glondu-Lassis, Murielle / Senesse, Pierre / Gutowski, Marian / Jacot, William / Lemanski, Claire / Amouyal, Michel / Azria, David / Guerdoux, Estelle / Bourgier, Céline

Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique

2021 Volume 26, Issue 4, Page(s) 637–645

Abstract: Adjuvant radiotherapy is one of the major anticancer treatments in early breast cancer patients. Acute and late radio-induced effects may occur during or after breast cancer radiotherapy, and their medical management is a major issue for radiation ... ...

Title translation	Non-pharmalogical interventions and breast cancer: What benefit in addition to radiotherapy?
Abstract	Adjuvant radiotherapy is one of the major anticancer treatments in early breast cancer patients. Acute and late radio-induced effects may occur during or after breast cancer radiotherapy, and their medical management is a major issue for radiation oncologists. Here, the present review of literature embraces complementary non-pharmacological interventions, which could be combined to adjuvant radiotherapy in order to improve patients care.
MeSH term(s)	Breast ; Breast Neoplasms/etiology ; Breast Neoplasms/radiotherapy ; Female ; Humans ; Radiotherapy, Adjuvant/adverse effects
Language	French
Publishing date	2021-10-28
Publishing country	France
Document type	Journal Article ; Review
ZDB-ID	1397169-4
ISSN	1769-6658 ; 1278-3218
ISSN (online)	1769-6658
ISSN	1278-3218
DOI	10.1016/j.canrad.2021.09.011
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Article ; Online: État des lieux de la formation initiale de l’internat d’oncologie après la quatrième vague pandémie de la COVID-19 : une enquête AERIO-SFJRO.

Rousseau, Adrien / Laune, Quentin / Ollivier, Luc / Naoun, Natacha / Alexandre, Jérôme / Giraud, Philippe / Azria, David / Delaye, Matthieu

Bulletin du cancer

2022 Volume 109, Issue 7-8, Page(s) 834–843

Abstract: Background: COVID-19 pandemic troubled hospital and university's organization. Previous study showed oncology resident's formation has been impacted by pandemic. One year later, we aimed to evaluate the state of oncology resident's formation.: Methods! ...

Title translation	Formation of French oncology resident: A national survey.
Abstract	Background: COVID-19 pandemic troubled hospital and university's organization. Previous study showed oncology resident's formation has been impacted by pandemic. One year later, we aimed to evaluate the state of oncology resident's formation. Methods: We conducted a transversal study written by AERIO and SJRO, released via social networks and mail to the French oncology residents. Results: One hundred and sixty-four residents answered. Sixty-four (39%) were male and 99 (60.4%) were female, mean age was 26.8 years old, mean semester was 5.7. One hundred and five (64%) were medical oncologist and 53 (32.3%) were radiation oncologist. One hundred and forty residents (85.4%) had lectures during hospital internships, mainly in cancer center (77.1%) and academic hospitals (60.7%). One hundred and twenty-one residents (73.8%) had specialized diploma lectures, in 34.7% of case monthly. Respectively 42.7% and 18.3% of residents could access to their formation's day respectively rarely and never. Strengths of oncology residency were scientific dynamism (91.9%), clinical breadth (82%) and knowledge renewal (78.9%). Attractivity's obstacles to the residency were psychological arduousness (64%), administrative burden (48.2%) and too important worktime (47%). Conclusion: This survey shows the state of play of French oncology residency's formation at the end of 2021.
MeSH term(s)	Adult ; COVID-19/epidemiology ; Female ; Humans ; Internship and Residency ; Male ; Medical Oncology/education ; Pandemics ; Surveys and Questionnaires
Language	French
Publishing date	2022-06-04
Publishing country	France
Document type	Journal Article
ZDB-ID	213270-9
ISSN	1769-6917 ; 0007-4551
ISSN (online)	1769-6917
ISSN	0007-4551
DOI	10.1016/j.bulcan.2022.04.004
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Article ; Online: Radiothérapie stéréotaxique (RTST) pulmonaire des tumeurs de moins de 3cm (stade I) et 5cm (stade II) non opérées : 10 ans d’expérience de l’Institut du Cancer de Montpellier (ICM).

Marguerit, A / Azria, D / Riou, O / Demontoy, S / Thezenas, S / Boisselier, P

Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique

2023 Volume 27, Issue 5, Page(s) 387–397

Abstract: Purpose: Search for predictive factors on survival and local control for less than 3 centimeters (cm) (stage I) and 5cm (stage II) inoperable lung tumors treated by Stereotactic Body Radiation Therapy (SBRT) in a retrospective monocentric study from ... ...

Title translation	Stereotactic Body Radiation Therapy for less than 3cm (stage I) and 5cm (stage II) inoperable lung tumors: 10 years experience of Montpellier Cancer Institute.
Abstract	Purpose: Search for predictive factors on survival and local control for less than 3 centimeters (cm) (stage I) and 5cm (stage II) inoperable lung tumors treated by Stereotactic Body Radiation Therapy (SBRT) in a retrospective monocentric study from Montpellier Cancer Institute (ICM) PATIENTS AND METHOD: Every patients treated at ICM for a stage I or II inoperable lung tumors from 2009 to 2019 were analyzed. Results: One hundred and seventy nine lesions were treated in 176 patients, with a major part (82,7%) in operated due to chronic obstructive pulmonary disease. Median overall survival for all patients was 71,7 months with a 35 months follow-up and the 2 years loco-regional free survival was 94,0 months. Better associated outcomes were stage I (median overall survival 71,7 versus 29,0 months P=0,004 ; HR=2,37 P=0,005), BED≥150Gy (median time-to-progression not reached versus 76,7 months P=0,025), small size of Planning Target Volume (PTV) (HR=0,42 P=0,032 when PTV<15,6 cc). 7,3% of all patients developed radiation pneumonitis. Conclusion: SBRT is associated with an excellent overall survival and a high rate of local control for less than 3cm (stage I) and 5cm (stage II) lung tumors but a low rate of toxicities. For these patients with many comorbidities, BED over 150Gy seems to be associated with a better loco-regional free survival, while cause of death is often other than lung cancer.
Language	French
Publishing date	2023-08-01
Publishing country	France
Document type	English Abstract ; Journal Article
ZDB-ID	1397169-4
ISSN	1769-6658 ; 1278-3218
ISSN (online)	1769-6658
ISSN	1278-3218
DOI	10.1016/j.canrad.2023.05.002
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Article: Le cancer du rein dans le département de L’Hérault : résultats de 30 ans d’enregistrement.

Hutin, M / Trétarre, B / Gras, C / Bessaoud, F / Daurès, J-P / Delbos, O / Bringer, J-P / Ayuso, D / Thuret, R / Azria, D / Serre, I / Brel, D / Reis Borges, R / Iborra, F / Rébillard, X

Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie

2020 Volume 31, Issue 3, Page(s) 175–182

Abstract: Objective: The objective of the study was to determine the specificities of renal cell carcinoma (RCC) in the department of Herault using the Herault Tumor Registry over 30 years.: Methods: Data of this study were obtained from the Herault cancer ... ...

Title translation	Renal cell carcinoma in the department of Hérault: Results over a 30 year period.
Abstract	Objective: The objective of the study was to determine the specificities of renal cell carcinoma (RCC) in the department of Herault using the Herault Tumor Registry over 30 years. Methods: Data of this study were obtained from the Herault cancer database. We analysed the evolution of RCC from 1987 to 2016, including the incidence, mortality, cancer pathology and staging at the moment of diagnosis. We compared our results with national and international data. Results: We identified 3769 newly diagnosed RCC: 2628 in men (69,7%) and 1141 in women (30,3%). In 2016, RCC was the 8th most frequent cancer, both genders combined, the 7th most frequent cancer in men and the 11th in women. New cases of RCC increased by 4.2 in men and 3.3 in women over the study period. The number of localised forms increased by 9% over 20 years. In 2016, the probability of having a RCC before the age of 75 was of 2.11% for a man and of 0.62% for a woman. Conclusion: Over 30 years, the incidence rate of RCC increased in the department of Herault; however, mortality decreased over the same period. This analytical data should be improved by the development of the Registry of Herault Specialised in Onco-Urology (RHESOU). Level of evidence: 3.
MeSH term(s)	Carcinoma, Renal Cell/epidemiology ; Carcinoma, Renal Cell/pathology ; Female ; France/epidemiology ; Humans ; Incidence ; Kidney Neoplasms/epidemiology ; Kidney Neoplasms/pathology ; Male ; Neoplasm Staging ; Registries ; Time Factors
Language	French
Publishing date	2020-11-05
Publishing country	France
Document type	Journal Article
ZDB-ID	1186190-3
ISSN	1166-7087
ISSN	1166-7087
DOI	10.1016/j.purol.2020.10.001
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Article ; Online: Compensation de la dose totale en cas d’interruption temporaire de radiothérapie externe dans le contexte de la pandémie de COVID-19 : mise au point pratique.

Azria, D / Hennequin, C / Giraud, P

Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique

2020 Volume 24, Issue 3, Page(s) 182–187

Abstract: Overall treatment time is an important factor of local recurrence and indirectly of distant evolution, namely in case of protracted treatments. The current pandemic impacts on the duration of radiotherapy if patients under treatments and synchronously ... ...

Title translation	Practical update of total dose compensation in case of temporary interruption of external radiotherapy in the COVID-19 pandemic context.
Abstract	Overall treatment time is an important factor of local recurrence and indirectly of distant evolution, namely in case of protracted treatments. The current pandemic impacts on the duration of radiotherapy if patients under treatments and synchronously suffering from COVID-19. The models used to compensate the total dose in case of temporary treatment interruption are well known but it is of importance in that pandemic context to update and homogenize clinical practice in order to improve local control without increasing normal tissue complications.
MeSH term(s)	Betacoronavirus ; Breast Neoplasms/radiotherapy ; COVID-19 ; Carcinoma, Non-Small-Cell Lung/radiotherapy ; Cell Proliferation ; Coronavirus Infections/epidemiology ; Female ; Humans ; Lung Neoplasms/radiotherapy ; Male ; Neoplasms/pathology ; Neoplasms/radiotherapy ; Pandemics ; Pneumonia, Viral/epidemiology ; Prostatic Neoplasms/radiotherapy ; Radiobiology/methods ; Radiotherapy Dosage ; SARS-CoV-2 ; Time Factors ; Uterine Cervical Neoplasms/radiotherapy ; Withholding Treatment
Keywords	covid19
Language	French
Publishing date	2020-04-10
Publishing country	France
Document type	Journal Article ; Review
ZDB-ID	1397169-4
ISSN	1769-6658 ; 1278-3218
ISSN (online)	1769-6658
ISSN	1278-3218
DOI	10.1016/j.canrad.2020.04.001
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Article ; Online: Présentation du siège. Recommandations pour la pratique clinique du CNGOF — Critères de sélection des femmes éligibles à une tentative d’accouchement par voie basse.

Azria, É

Gynecologie, obstetrique, fertilite & senologie

2019 Volume 48, Issue 1, Page(s) 120–131

Abstract: Objective: The objective of this chapter is to examine on the basis of the knowledge currently available the criteria available before labour for selecting women who would be eligible for trial of vaginal delivery.: Methodology: Bibliographical ... ...

Title translation	Breech Presentation: CNGOF Guidelines for Clinical Practice - Case Selection for Trial of Labour.
Abstract	Objective: The objective of this chapter is to examine on the basis of the knowledge currently available the criteria available before labour for selecting women who would be eligible for trial of vaginal delivery. Methodology: Bibliographical research in French and English using the Medline and Cochrane databases between 1980 and 2019 and the recommendations of international societies. Results: It is recommended to offer women who wish to attempt a vaginal delivery at term a pelvimetry to decide with them on their mode of delivery (Grade C). The pelvimetric standards used at the time of the PREMODA study were anteroposterior diameter of inlet≥105mm, a transverse diameter of inlet≥120mm, a transverse interspinous diameter≥100mm. However, since there is no evidence about which pelvic measures to use, nor any evidence to set decision-making thresholds other than those set in published studies, the selected decision-making thresholds can be adjusted according to gestational age at delivery or fetal biometrics (Professional consensus). There is no argument for recommending the practice of pelvimetry in the case of delivery before 37 weeks gestational age (Professional consensus) and in the case of breech presentation discovered at the time of beginning of labour, the absence of pelvimetry alone does not contraindicate the attempt of vaginal delivery (Professional consensus). There is insufficient data to recommend the systematic use of fetal weight estimation and/or biparietal diameter measurement as acceptance criteria for a vaginal delivery attempt. In the event of a known fetal weight estimation before birth greater than 3800g, a cesarean section is to be preferred (Professional consensus). The breech presentation is not in itself a contraindication to an attempt of vaginal delivery for a small fetus for gestational age (Professional consensus). The presentation of the non-frank breech is not in itself a contraindication to an attempt of vaginal delivery (Professional consensus). In the case of premature breech delivery, current data do not allow to recommend one delivery route over another (Professional consensus). It is recommended to check the absence of hyperextension of the fetal head by ultrasound before an attempt of vaginal delivery (Professional consensus) and to prefer a cesarean section if such a position is found (Professional consensus). It is not recommended to propose a caesarean section with the sole reason of nulliparity (Grade C). The history of cesarean section is not in itself a contraindication to an attempt of vaginal delivery in the case of fetal breech presentation (Professional consensus). Premature rupture of the membranes is not in itself a contraindication to an attempt of vaginal delivery (Professional consensus). Conclusion: A number of the factors analyzed in this chapter are to be incorporated into the decision-making process in order to choose with the woman whose fetus is in breech presentation the delivery route.
MeSH term(s)	Breech Presentation/therapy ; Cesarean Section ; Delivery, Obstetric/methods ; Female ; France ; Gestational Age ; Humans ; MEDLINE ; Parity ; Pelvimetry ; Pregnancy ; Trial of Labor ; Ultrasonography, Prenatal
Language	French
Publishing date	2019-10-31
Publishing country	France
Document type	Journal Article ; Practice Guideline
ZDB-ID	2887456-0
ISSN	2468-7189
ISSN (online)	2468-7189
DOI	10.1016/j.gofs.2019.10.026
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Article: Le cancer des organes génitaux externes de l’homme dans le département de l’Hérault: résultats de 30 ans d’enregistrement du registre des tumeurs de l’Hérault (1987–2016).

Zarka, M / Tretarre, B / Rebillard, X / Murez, T / Daures, J P / Azria, D / Serre, I / Brel, D / Ramay, A S / Reis Borges, R / Gevorgyan, A / Hutin, M / Marchal, S / Korahanis, N / Iborra, F / Thuret, R

Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie

2021 Volume 31, Issue 5, Page(s) 282–292

Abstract: Aim: The objective of this study is to present the history of cancers of the external genital organs of male in Hérault using data from the Hérault tumor register (RTH) over a period of 30 years.: Patients and methods: Using the RTH database, we ... ...

Title translation	Cancers of the external genital organs of male in Hérault: Results from the Hérault tumor register (RTH) over a period of 30 years (1987-2016).
Abstract	Aim: The objective of this study is to present the history of cancers of the external genital organs of male in Hérault using data from the Hérault tumor register (RTH) over a period of 30 years. Patients and methods: Using the RTH database, we studied the development of testicular germ cell tumors (TGCT) and penile cancer (PC) over 30 years, from 1987 to 2016. We analyzed the incidence and mortality data for these tumors. We compared these results to French, European and global data. Results: In 30 years of registration we have recorded 725 cases of TGCT and 175 cases of PC. The age standardized incidence rate (ASR) of TGCT has doubled between 1987 and 2016 (4.2 per 100,000 in 1987 and 9.3 per 100,000 in 2016). It was multiplied by 2.63 in the population of patients aged 30 to 44. There is a decrease of the mortality rate with a ASR of 0.8 deaths per 100,000 in 1987, and 0.4/100 000 in 2016. The PC incidence ASR was stable between 1987 and 2016 (0.4-0.9/100,000). Mortality is stable with a ASR between 0.1 and 0.3 deaths per 100,000 between 1987 and 2016. Conclusion: The incidence of TGCT has increased sharply in the Hérault over the past 30 years, while a decrease in mortality has been observed. The proportion of seminomas is increasing; it has gone from 53 % to 60 % in 30 years in the Hérault. The incidence and mortality of PC shows a stability in the Hérault over the past 30 years.
MeSH term(s)	Adult ; France/epidemiology ; Humans ; Incidence ; Male ; Neoplasms, Germ Cell and Embryonal/epidemiology ; Penile Neoplasms/epidemiology ; Registries ; Testicular Neoplasms/epidemiology ; Time Factors
Language	French
Publishing date	2021-02-13
Publishing country	France
Document type	Journal Article
ZDB-ID	1186190-3
ISSN	1166-7087
ISSN	1166-7087
DOI	10.1016/j.purol.2020.08.054
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Article ; Online: Compensation de la dose totale en cas d’interruption temporaire de radiothérapie externe dans le contexte de la pandémie de COVID-19

Azria, D. / Hennequin, C. / Giraud, P.

Cancer/Radiothérapie

mise au point pratique

2020 Volume 24, Issue 3, Page(s) 182–187

Keywords	Oncology ; Radiology Nuclear Medicine and imaging ; covid19
Language	French
Publisher	Elsevier BV
Publishing country	us
Document type	Article ; Online
ZDB-ID	1397169-4
ISSN	1278-3218
ISSN	1278-3218
DOI	10.1016/j.canrad.2020.04.001
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In stock of ZB MED Cologne/Königswinter

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