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  1. Article ; Online: Loss function of SL (sekiguchi lesion) in the rice cultivar Minghui 86 leads to enhanced resistance to (hemi)biotrophic pathogens.

    Tian, Dagang / Yang, Fang / Niu, Yuqing / Lin, Yan / Chen, Zaijie / Li, Gang / Luo, Qiong / Wang, Feng / Wang, Mo

    BMC plant biology

    2020  Volume 20, Issue 1, Page(s) 507

    Abstract: ... in an indica rice restore line Minghui 86 (MH86), named as sl-MH-1, - 2 and - 3, all of which present ...

    Abstract Background: Serotonin, originally identified as a neurotransmitter in mammals, functions as an antioxidant to scavenge cellular ROS in plants. In rice, the conversion of tryptamine to serotonin is catalyzed by SL (sekiguchi lesion), a member of cytochrome P450 monooxygenase family. The sl mutant, originated from rice cultivar Sekiguchi-asahi, exhibits spontaneous lesions, whereas its immune responses to pathogens have not been clearly characterized.
    Results: Here we identified three allelic mutants of SL in an indica rice restore line Minghui 86 (MH86), named as sl-MH-1, - 2 and - 3, all of which present the typical lesions under normal growth condition. Compared with those in MH86, the serotonin content in sl-MH-1 is dramatically decreased, whereas the levels of tryptamine and L-trytophan are significantly increased. The sl-MH-1 mutant accumulates high H
    Conclusions: Our results indicate that SL, involving in the final step of serotonin biosynthesis, negatively regulates rice resistance against (hemi)biotrophic pathogens via compromising the PTI responses and defense hormones accumulation.
    MeSH term(s) Disease Resistance/genetics ; Genes, Plant/genetics ; Genes, Plant/physiology ; Loss of Function Mutation/genetics ; Loss of Function Mutation/physiology ; Oryza/genetics ; Oryza/immunology ; Oxidative Stress ; Plant Diseases/immunology ; Plant Diseases/microbiology ; Plant Leaves/metabolism ; Reactive Oxygen Species/metabolism ; Serotonin/metabolism ; Tryptamines/metabolism
    Chemical Substances Reactive Oxygen Species ; Tryptamines ; Serotonin (333DO1RDJY) ; tryptamine (422ZU9N5TV)
    Language English
    Publishing date 2020-11-04
    Publishing country England
    Document type Journal Article
    ISSN 1471-2229
    ISSN (online) 1471-2229
    DOI 10.1186/s12870-020-02724-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Loss function of SL (sekiguchi lesion) in the rice cultivar Minghui 86 leads to enhanced resistance to (hemi)biotrophic pathogens

    Tian, Dagang / Yang, Fang / Niu, Yuqing / Lin, Yan / Chen, Zaijie / Li, Gang / Luo, Qiong / Wang, Feng / Wang, Mo

    BMC Plant Biol. 2020 Dec., v. 20, no. 1 p.507-507

    2020  

    Abstract: ... in an indica rice restore line Minghui 86 (MH86), named as sl-MH-1, − 2 and − 3, all of which present ...

    Abstract BACKGROUND: Serotonin, originally identified as a neurotransmitter in mammals, functions as an antioxidant to scavenge cellular ROS in plants. In rice, the conversion of tryptamine to serotonin is catalyzed by SL (sekiguchi lesion), a member of cytochrome P450 monooxygenase family. The sl mutant, originated from rice cultivar Sekiguchi-asahi, exhibits spontaneous lesions, whereas its immune responses to pathogens have not been clearly characterized. RESULTS: Here we identified three allelic mutants of SL in an indica rice restore line Minghui 86 (MH86), named as sl-MH-1, − 2 and − 3, all of which present the typical lesions under normal growth condition. Compared with those in MH86, the serotonin content in sl-MH-1 is dramatically decreased, whereas the levels of tryptamine and L-trytophan are significantly increased. The sl-MH-1 mutant accumulates high H₂O₂ level at its lesion sites and is more sensitive to exogenous H₂O₂ treatment than the wild type. When treated with the reductant vitamin C (Vc), the lesion formation on sl-MH-1 leaves could be efficiently suppressed. In addition, sl-MH-1 displayed more resistant to both the blast fungus and blight bacteria, Pyricularia oryzae (P. oryzae, teleomorph: Magnaporthe oryzae) and Xanthomonas oryzae pv. Oryzae (Xoo), respectively. The pathogen-associated molecular patterns (PAMPs)-triggered immunity (PTI) responses, like reactive oxygen species (ROS) burst and callose deposition, were enhanced in sl-MH-1. Moreover, loss function of SL resulted in higher resting levels of the defense hormones, salicylic acid and jasmonic acid. The RNA-seq analysis indicated that after P. oryzae infection, transcription of the genes involved in reduction-oxidation regulation was the most markedly changed in sl-MH-1, compared with MH86. CONCLUSIONS: Our results indicate that SL, involving in the final step of serotonin biosynthesis, negatively regulates rice resistance against (hemi)biotrophic pathogens via compromising the PTI responses and defense hormones accumulation.
    Keywords Magnaporthe oryzae ; Xanthomonas oryzae pv. oryzae ; ascorbic acid ; biosynthesis ; blight ; callose ; cultivars ; cytochrome P-450 ; fungi ; immunity ; jasmonic acid ; mutants ; neurotransmitters ; reactive oxygen species ; reducing agents ; rice ; salicylic acid ; sequence analysis ; serotonin ; teleomorphs ; tryptamine
    Language English
    Dates of publication 2020-12
    Size p. 507.
    Publishing place BioMed Central
    Document type Article ; Online
    ZDB-ID 2059868-3
    ISSN 1471-2229
    ISSN 1471-2229
    DOI 10.1186/s12870-020-02724-6
    Database NAL-Catalogue (AGRICOLA)

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  3. Article ; Online: Rapid Development of Orthopaedic Trauma in China.

    Yang, Minghui / Wu, Xinbao

    Injury

    2023  Volume 54 Suppl 2, Page(s) S1–S2

    MeSH term(s) Humans ; Orthopedics ; China/epidemiology ; Trauma Centers
    Language English
    Publishing date 2023-04-07
    Publishing country Netherlands
    Document type Editorial ; Comment
    ZDB-ID 218778-4
    ISSN 1879-0267 ; 0020-1383
    ISSN (online) 1879-0267
    ISSN 0020-1383
    DOI 10.1016/j.injury.2023.03.015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 778: Show issues Location:
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  4. Article ; Online: Activatable organic probes for in situ imaging of biomolecules.

    Li, Ke / Yang, Minghui

    Chemistry, an Asian journal

    2024  Volume 19, Issue 3, Page(s) e202301037

    Abstract: Biomolecules are fundamental for various chemical and biological processes of living organisms. High-resolution in situ imaging of the dynamics and local distribution of biomolecules may facilitate better interpretation of diverse complex cell events in ... ...

    Abstract Biomolecules are fundamental for various chemical and biological processes of living organisms. High-resolution in situ imaging of the dynamics and local distribution of biomolecules may facilitate better interpretation of diverse complex cell events in the biomedicine field. In different advanced imaging tools, fluorescence imaging-based activatable organic probes can be noninvasively and effortlessly internalized into cells and can be easily modified, which is essential for the in situ imaging of targets in living organisms. We here briefly summarize the existing general design strategies of activatable organic probes for retaining the fluorescence signal inside cells. We particularly describe the bioapplication of these probes for the in situ bioimaging. This review is expected to promote the development of new molecular tools for extending the application of these in situ imaging strategies to other biomolecules.
    MeSH term(s) Fluorescent Dyes/chemistry ; Optical Imaging/methods
    Chemical Substances Fluorescent Dyes
    Language English
    Publishing date 2024-01-02
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 2233006-9
    ISSN 1861-471X ; 1861-4728
    ISSN (online) 1861-471X
    ISSN 1861-4728
    DOI 10.1002/asia.202301037
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Predicting Rate Constants of Alkane Cracking Reactions Using Machine Learning.

    Zhang, Yu / Xia, Min / Song, Hongwei / Yang, Minghui

    The journal of physical chemistry. A

    2024  Volume 128, Issue 12, Page(s) 2383–2392

    Abstract: Calculating the thermal rate constants of elementary combustion reactions is of great importance in theoretical chemistry. Machine learning has become a powerful, data-driven method for predicting rate constants nowadays. Recently, the molecular ... ...

    Abstract Calculating the thermal rate constants of elementary combustion reactions is of great importance in theoretical chemistry. Machine learning has become a powerful, data-driven method for predicting rate constants nowadays. Recently, the molecular similarity combined with the topological indices were proposed to represent the hydrogen abstraction reactions of alkane [
    Language English
    Publishing date 2024-03-13
    Publishing country United States
    Document type Journal Article
    ISSN 1520-5215
    ISSN (online) 1520-5215
    DOI 10.1021/acs.jpca.4c00912
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Lattice Thermal Conductivity in XMg

    Wu, Minghui / Yang, Hongping / Xie, Fengyan / Huang, Li

    Materials (Basel, Switzerland)

    2023  Volume 16, Issue 23

    Abstract: The binary compound ... ...

    Abstract The binary compound Mg
    Language English
    Publishing date 2023-11-25
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma16237349
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Comparison of saline infusion test and captopril challenge test in the diagnosis of Chinese with primary aldosteronism in different age groups.

    Sun, Kaiwen / Gong, Minghui / Yu, Yang / Yang, Minghui / Zhang, Ying / Jiang, Yinong / Song, Wei

    Frontiers in endocrinology

    2024  Volume 15, Page(s) 1343704

    Abstract: Background: To explore the diagnostic accuracy and the optimal cutoff value between the saline infusion test (SIT) and captopril challenge test (CCT) [including the value and suppression of plasma aldosterone concentration (PAC)] for primary ... ...

    Abstract Background: To explore the diagnostic accuracy and the optimal cutoff value between the saline infusion test (SIT) and captopril challenge test (CCT) [including the value and suppression of plasma aldosterone concentration (PAC)] for primary aldosteronism (PA) diagnosing.
    Methods: A total of 318 patients with hypertension were consecutively enrolled, including 126 patients with PA and 192 patients with essential hypertension (EH), in this observational study. The characteristics of patients and laboratory examinations were collected and compared. The comparison between SIT and CCT was carried by drawing the receiver operator characteristic curve (ROC) and calculating the area under the curve (AUC) to explore the diagnostic accuracy and the optimal cutoff value.
    Results: The average age was 51.59 ± 10.43 in the PA group and 45.72 ± 12.44 in the EH group (
    Conclusion: Compared with SIT, CCT had a higher diagnostic value when post-CCT PAC was used as the diagnostic criterion in Chinese people, while the selection of diagnostic thresholds depended on patient age.
    MeSH term(s) Humans ; Adult ; Middle Aged ; Captopril ; Hyperaldosteronism/diagnosis ; Aldosterone ; Essential Hypertension/diagnosis ; China/epidemiology ; East Asian People
    Chemical Substances Captopril (9G64RSX1XD) ; Aldosterone (4964P6T9RB)
    Language English
    Publishing date 2024-03-22
    Publishing country Switzerland
    Document type Observational Study ; Journal Article
    ZDB-ID 2592084-4
    ISSN 1664-2392
    ISSN 1664-2392
    DOI 10.3389/fendo.2024.1343704
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Corrigendum to "Icariin improves learning and memory function in Aβ

    Wan, Meiyu / Sun, Shengqi / Di, Xiaoke / Zhao, Minghui / Lu, Fengjuan / Zhang, Zhifei / Li, Yang

    Journal of ethnopharmacology

    2024  Volume 325, Page(s) 117906

    Language English
    Publishing date 2024-02-15
    Publishing country Ireland
    Document type Published Erratum
    ZDB-ID 134511-4
    ISSN 1872-7573 ; 0378-8741
    ISSN (online) 1872-7573
    ISSN 0378-8741
    DOI 10.1016/j.jep.2024.117906
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Metal nitrides for seawater electrolysis.

    Hu, Huashuai / Wang, Xiaoli / Attfield, J Paul / Yang, Minghui

    Chemical Society reviews

    2024  Volume 53, Issue 1, Page(s) 163–203

    Abstract: Electrocatalytic high-throughput seawater electrolysis for hydrogen production is a promising green energy technology that offers possibilities for environmental and energy sustainability. However, large-scale application is limited by the complex ... ...

    Abstract Electrocatalytic high-throughput seawater electrolysis for hydrogen production is a promising green energy technology that offers possibilities for environmental and energy sustainability. However, large-scale application is limited by the complex composition of seawater, high concentration of Cl
    Language English
    Publishing date 2024-01-02
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1472875-8
    ISSN 1460-4744 ; 0306-0012
    ISSN (online) 1460-4744
    ISSN 0306-0012
    DOI 10.1039/d3cs00717k
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Convenient Size Analysis of Nanoplastics on a Microelectrode.

    He, Xuan / Xie, Xin / Xiang, Juan / Yang, Minghui

    Analytical chemistry

    2024  Volume 96, Issue 16, Page(s) 6180–6185

    Abstract: Chemical recycling is a promising approach to reduce plastic pollution. Timely and accurate size analysis of produced nanoplastics is necessary to monitor the process and assess the quality of chemical recycling. In this work, a sandwich-type ... ...

    Abstract Chemical recycling is a promising approach to reduce plastic pollution. Timely and accurate size analysis of produced nanoplastics is necessary to monitor the process and assess the quality of chemical recycling. In this work, a sandwich-type microelectrode sensor was developed for the size assessment of nanoplastics. β-Mercaptoethylamine was modified on the microelectrode to enhance its surface positive charge density. Polystyrene (PS) nanoplastics were captured on the sensor through electrostatic interactions. Ferrocene was used as an electrochemical beacon and attached to PS via hydrophobic interactions. The results show a nonlinear dependence of the sensor's current response on the PS particle size. The size resolving ability of the microelectrode is mainly attributed to the small size of the electrode and the resulting attenuation of the electric field strength. For mixed samples with different particle sizes, this method can provide accurate average particle sizes. Through an effective pretreatment process, the method can be applied to PS nanoplastics with different surface properties, ensuring its application in evaluating different chemical recycling methods.
    Language English
    Publishing date 2024-04-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1508-8
    ISSN 1520-6882 ; 0003-2700
    ISSN (online) 1520-6882
    ISSN 0003-2700
    DOI 10.1021/acs.analchem.3c05065
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