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  1. Book: Nei wai shi san ke yan fang wu qian zhong

    Huang, Bochui / Wang, Mengying

    2001  

    Title translation 5000 proven remedies of 13 subjects of internal and external medicine.
    Title variant Nei wai 13 ke yan fang 5000 zhong ; Jing yan liang fang da quan
    Author's details Huang Bochui zhu ; Wang Mengying xu bian ; Du Jiehui dian jiao ; Wang Guoqiang zhu shen
    MeSH term(s) Materia Medica/administration & dosage ; Medicine, Chinese Traditional
    Language Chinese
    Size 2, 5, 2, 544 p. ;, 21 cm.
    Edition Di 1 ban.
    Publisher Zhongguo ren kou chu ban she
    Publishing place Beijing Shi
    Document type Book
    ISBN 9787800796487 ; 7800796485
    Database Catalogue of the US National Library of Medicine (NLM)

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  2. Book: Qi Bai shi zhuan ke jing pin shang xi

    Wang, Xingyi

    2000  

    Author's details Wang Xingyi bianzhu
    Language Chinese
    Size 90 S, Ill
    Edition Di 1 ban
    Publisher Xiling yinshe
    Publishing place Hangzhou
    Document type Book
    ISBN 7805174806 ; 9787805174808
    Database Former special subject collection: coastal and deep sea fishing

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  3. Book: Fu shi nü ke jia chuan ying yong

    Wang, Peizhang / Fu, Shan

    1987  

    Title translation Clinical applications of Dr. Fu's gynecological therapeutics, adopted and practiced for generations, with case studies.
    Author's details Wang Peizhang bian zhu
    MeSH term(s) Genital Diseases, Female/therapy
    Language Chinese
    Size 2, 123 p. :, port.
    Edition Di 1 ban.
    Publisher Shanxi ke xue jiao yu chu ban she
    Publishing place Taiyuan
    Document type Book
    Database Catalogue of the US National Library of Medicine (NLM)

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  4. Article ; Online: Different influences on tacrolimus pharmacokinetics by coadministrations of zhi ke and zhi shi in rats.

    Lin, Shiuan-Pey / Wu, Ping-Ping / Hou, Yu-Chi / Tsai, Shang-Yuan / Wang, Meng-Ju / Fang, Shih-Hua / Chao, Pei-Dawn Lee

    Evidence-based complementary and alternative medicine : eCAM

    2011  Volume 2011, Page(s) 751671

    Abstract: ... with and without Zhi Ke and Zhi Shi decoctions in a cross-over design. Blood samples were withdrawn via ... patients. Grapefruit juice and pomelo have been reported to increase the blood levels of tacrolimus. Zhi Ke ... and Zhi Shi, the ripe peels and unripe fruits of Citrus aurantium which is chemotaxonomically related ...

    Abstract Tacrolimus, an immunosuppressant with narrow therapeutic window, has been used widely in transplant patients. Grapefruit juice and pomelo have been reported to increase the blood levels of tacrolimus. Zhi Ke and Zhi Shi, the ripe peels and unripe fruits of Citrus aurantium which is chemotaxonomically related to grapefruit and pomelo, are in wide use in clinical Chinese medicine. To investigate the possible interaction of these two Citrus herbs with tacrolimus, male Sprague-Dawley rats were orally given tacrolimus (1.5 mg/kg) with and without Zhi Ke and Zhi Shi decoctions in a cross-over design. Blood samples were withdrawn via cardiopuncture at specific time and quantitated by a microparticle enzyme immunoassay. In addition, to explore the mechanism of interaction, LS 180 cell line was used for the transport study of rhodamine 123, a typical substrate of P-glycoprotein (P-gp). The results showed that Zhi Shi significantly decreased the C(max) and AUC(0-t) of tacrolimus by 72.4% and 72.0%, respectively, whereas Zhi Ke did not affect tacrolimus pharmacokinetics. LS 180 cell line study indicated that Zhi Shi increased the efflux activity of P-gp, enabling us to explain the decreased oral bioavailability of tacrolimus caused by Zhi Shi. Hence, we suggest that Zhi Shi be contraindicated for transplant patients treated with tacrolimus to reduce the risk of allograft rejection.
    Language English
    Publishing date 2011-01-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2171158-6
    ISSN 1741-4288 ; 1741-427X
    ISSN (online) 1741-4288
    ISSN 1741-427X
    DOI 10.1155/2011/751671
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5995: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Book: Shi yong Zhong xi yi jie he zhong liu nei ke xue

    Wang, Xiaomin

    2014  

    Author's details zhu bian Wang Xiaomin
    MeSH term(s) Neoplasms/therapy ; Integrative Medicine ; Medicine, Chinese Traditional
    Language Chinese
    Size 2, 6, 300 pages
    Edition Di 1 ban.
    Document type Book
    ISBN 9787513220170 ; 7513220174
    Database Catalogue of the US National Library of Medicine (NLM)

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  6. Book: [Siming Song shi nü ke mi shu]

    Song, Lin'gao / Wang, Shuxiang

    [Gynecology,

    (Zhongguo yi yao cong shu)

    1960  

    Author's details ed. by Wang Shuxiang
    Series title Zhongguo yi yao cong shu
    Language Chinese
    Size 2, 2, 2, 112 p.
    Publisher Taiwan dong fang shu dian
    Publishing place Taipeh
    Document type Book
    Database Catalogue of the US National Library of Medicine (NLM)

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  7. Book: Shi jia chen yin ke zhuan

    Wang, Rongzu

    2005  

    Author's details Wang rong zu zhu
    Keywords Historians/Biography
    Language Chinese
    Size [14], 275 p., [8] p. of plates, ill, 23 cm
    Edition Di 1 ban
    Publisher Bei jing da xue chu ban she
    Publishing place Bei jing
    Document type Book
    Note Includes bibliographical references (p. 261-275)
    ISBN 7301077564 ; 9787301077566
    Database Former special subject collection: coastal and deep sea fishing

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    Order via subito

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    Inter-library loan at ZB MED

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  8. Book: Guo ji Han yu jiao shi ke tang ji qiao jiao xue shou ce

    Wang, Wei / 王巍 / Sun, Qi / 孙淇

    Handbook on classroom skills for international Chinese teachers

    (Guo ji Han yu jiao shi ke tang jiao xue zi yuan cong shu ; 国际汉语教师课堂教学资源丛书)

    2011  

    Title variant Handbook on classroom skills for international Chinese teachers
    Author's details Wang Wei, Sun Qi (Han guo) bian zhu
    Series title Guo ji Han yu jiao shi ke tang jiao xue zi yuan cong shu
    国际汉语教师课堂教学资源丛书
    Keywords Chinese language/Study and teaching/Foreign speakers
    Language Chinese
    Size 262 p, ill, 29 cm
    Publisher Gao deng jiao yu chu ban she ; 高等教育出版社
    Publishing place Bei jing ; 北京
    Document type Book
    Note Spiral binding
    ISBN 7040306549 ; 9787040306545
    Database Former special subject collection: coastal and deep sea fishing

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    Order via subito

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    Inter-library loan at ZB MED

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  9. Book: Dan dao yu dan yi shi er zhi chang qu yu wai ke shou shu tu pu

    Wang, Qinyao

    2013  

    Title variant Surgical atlas of biliary tract and biliary-pancreatic-duodenal region
    Author's details zhu bian Wang Qinyao = Surgical atlas of biliary tract and biliary-pancreatic-duodenal region / edited by Wang Qinyao
    MeSH term(s) Digestive System Surgical Procedures
    Language Chinese ; English
    Size xxv, 735 pages :, illustrations
    Edition Di 1 ban.
    Document type Book
    Note In Chinese and English.
    ISBN 9787030360533 ; 7030360532
    Database Catalogue of the US National Library of Medicine (NLM)

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    Order via subito

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  10. Article ; Online: Different Influences on Tacrolimus Pharmacokinetics by Coadministrations of Zhi Ke and Zhi Shi in Rats

    Shiuan-Pey Lin / Ping-Ping Wu / Yu-Chi Hou / Shang-Yuan Tsai / Meng-Ju Wang / Shih-Hua Fang / Pei-Dawn Lee Chao

    Evidence-Based Complementary and Alternative Medicine, Vol

    2011  Volume 2011

    Abstract: ... with and without Zhi Ke and Zhi Shi decoctions in a cross-over design. Blood samples were withdrawn via ... patients. Grapefruit juice and pomelo have been reported to increase the blood levels of tacrolimus. Zhi Ke ... and Zhi Shi, the ripe peels and unripe fruits of Citrus aurantium which is chemotaxonomically related ...

    Abstract Tacrolimus, an immunosuppressant with narrow therapeutic window, has been used widely in transplant patients. Grapefruit juice and pomelo have been reported to increase the blood levels of tacrolimus. Zhi Ke and Zhi Shi, the ripe peels and unripe fruits of Citrus aurantium which is chemotaxonomically related to grapefruit and pomelo, are in wide use in clinical Chinese medicine. To investigate the possible interaction of these two Citrus herbs with tacrolimus, male Sprague-Dawley rats were orally given tacrolimus (1.5 mg/kg) with and without Zhi Ke and Zhi Shi decoctions in a cross-over design. Blood samples were withdrawn via cardiopuncture at specific time and quantitated by a microparticle enzyme immunoassay. In addition, to explore the mechanism of interaction, LS 180 cell line was used for the transport study of rhodamine 123, a typical substrate of P-glycoprotein (P-gp). The results showed that Zhi Shi significantly decreased the Cmax⁡ and AUC0-t of tacrolimus by 72.4% and 72.0%, respectively, whereas Zhi Ke did not affect tacrolimus pharmacokinetics. LS 180 cell line study indicated that Zhi Shi increased the efflux activity of P-gp, enabling us to explain the decreased oral bioavailability of tacrolimus caused by Zhi Shi. Hence, we suggest that Zhi Shi be contraindicated for transplant patients treated with tacrolimus to reduce the risk of allograft rejection.
    Keywords Other systems of medicine ; RZ201-999
    Subject code 610
    Language English
    Publishing date 2011-01-01T00:00:00Z
    Publisher Hindawi Limited
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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