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Article ; Online: Three-Dimensional Doppler Mapping of Placental Chorioangioma Prior to Fetoscopic Laser Ablation.

Czeresnia, Ricardo Mamber / Trad, Ayssa Teles Abrao / Narang, Kavita / Wyatt, Michelle / Ruano, Rodrigo

Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine

2021 Volume 41, Issue 1, Page(s) 255–257

MeSH term(s)	Female ; Fetofetal Transfusion/surgery ; Fetoscopy ; Hemangioma/diagnostic imaging ; Hemangioma/surgery ; Humans ; Laser Therapy ; Placenta/diagnostic imaging ; Placenta Diseases/diagnostic imaging ; Placenta Diseases/surgery ; Pregnancy ; Ultrasonography, Prenatal
Language	English
Publishing date	2021-03-10
Publishing country	England
Document type	Letter
ZDB-ID	604829-8
ISSN	1550-9613 ; 0278-4297
ISSN (online)	1550-9613
ISSN	0278-4297
DOI	10.1002/jum.15680
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Zs.A 1793: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 495: Show issues

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Article ; Online: Sonographic pulmonary response after tracheal occlusion in fetuses with severe isolated congenital diaphragmatic hernia.

Trad, Ayssa Teles Abrao / Czeresnia, Ricardo / Ibirogba, Eniola / Narang, Kavita / Ruano, Rodrigo

Journal of clinical ultrasound : JCU

2022 Volume 50, Issue 2, Page(s) 185–190

Abstract: Purpose: To report the longitudinal lung growth and prognosis of fetuses with severe left sided congenital diaphragmatic hernia (CDH) treated with fetoscopic tracheal occlusion (FETO) in a single institution.: Methods: Fetal lung size (observed-to- ... ...

Abstract	Purpose: To report the longitudinal lung growth and prognosis of fetuses with severe left sided congenital diaphragmatic hernia (CDH) treated with fetoscopic tracheal occlusion (FETO) in a single institution. Methods: Fetal lung size (observed-to-expected lung area to head circumference [o/e-LHR]) was measured in seven consecutive fetuses with isolated severe left-sided CDH who underwent FETO. Fetal lung growth was used to prognosticate survival and need for ECMO. Results: Seven consecutive fetuses had a FETO procedure in the timeframe of this study. A total of 44 longitudinal ultrasound were performed to evaluate lung development. FETO was performed at GA 28.5 ± 0.5 weeks. Five (71.4%) infants survived to one-year follow-up and ECMO was needed in three patients (42.8%). Fetal lung response was observed in all fetuses; mean o/e-LHR increased from 22.5% ± 1.4 before FETO to 44.4% ± 9.8 before delivery. Infants who survived had a higher percentage of fetal lung growth (21.8%) than those who died (8.25%). Conclusion: Our study supports the hypothesis that FETO promotes fetal lung growth in fetuses with severe left-sided CDH, and the fetal pulmonary response seems to be associated with improved outcomes after the procedure.
Language	English
Publishing date	2022-01-12
Publishing country	United States
Document type	Journal Article
ZDB-ID	189393-2
ISSN	1097-0096 ; 0091-2751
ISSN (online)	1097-0096
ISSN	0091-2751
DOI	10.1002/jcu.23121
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Zs.A 1186: Show issues

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Article ; Online: Abdominal and robotic sacrocolpopexy costs following implementation of enhanced recovery after surgery.

Baker, Mary V / Teles Abrao Trad, Ayssa / Tamhane, Prajakta / Weaver, Amy L / Visscher, Sue L / Borah, Bijan J / Klingele, Christopher J / Gebhart, John B / Trabuco, Emanuel C

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics

2023 Volume 161, Issue 2, Page(s) 655–660

Abstract: Objective: To compare perioperative costs and morbidity between open and robotic sacrocolpopexy after implementation of enhanced recovery after surgery (ERAS) pathway.: Methods: The present retrospective cohort study of patients undergoing open or ... ...

Abstract	Objective: To compare perioperative costs and morbidity between open and robotic sacrocolpopexy after implementation of enhanced recovery after surgery (ERAS) pathway. Methods: The present retrospective cohort study of patients undergoing open or robotic sacrocolpopexy (January 1, 2014, through November 30, 2017) used an ERAS protocol with liposomal bupivacaine infiltration of laparotomy incisions. Primary outcomes were costs associated with index surgery and hospitalization, determined with Medicare cost-to-charge ratios and reimbursement rates and adjusted for variables expected to impact costs. Secondary outcomes included narcotic use, length of stay (LOS), and complications from index hospitalization to postoperative day 30. Results: For the total of 231 patients (open cohort, 90; robotic cohort, 141), the adjusted mean cost of robotic surgery was $3239 higher compared with open sacrocolpopexy (95% confidence interval [CI] $1331-$5147; P < 0.001). Rates were not significantly different for intraoperative complications (robotic, 4.3% [6/141]; open, 5.6% [5/90]; P = 0.754), 30-day postoperative complications (robotic, 11.4% [16/141]; open, 16.7% [15/90]; P = 0.322), or readmissions (robotic, 5.7% [8/141]; open, 3.3% [3/90]; P = 0.535). The percentage of patients dismissed on postoperative day 1 was greater in the robotic group (89.4% [126/141] vs. 48.9% [44/90], P < 0.001). Conclusions: Decreased LOS associated with ERAS provided significant cost savings with open sacrocolpopexy versus robotic sacrocolpopexy without adverse impacts on perioperative complications or readmissions.
MeSH term(s)	Aged ; Humans ; United States ; Robotic Surgical Procedures/adverse effects ; Robotic Surgical Procedures/methods ; Enhanced Recovery After Surgery ; Retrospective Studies ; Medicare ; Robotics ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Length of Stay
Language	English
Publishing date	2023-01-09
Publishing country	United States
Document type	Journal Article
ZDB-ID	80149-5
ISSN	1879-3479 ; 0020-7292
ISSN (online)	1879-3479
ISSN	0020-7292
DOI	10.1002/ijgo.14623
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Zs.A 355: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: What do we know about the diagnosis and management of mirror syndrome?

Teles Abrao Trad, Ayssa / Czeresnia, Ricardo / Elrefaei, Amro / Ibirogba, Eniola R / Narang, Kavita / Ruano, Rodrigo

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians

2021 Volume 35, Issue 20, Page(s) 4022–4027

Abstract: Introduction: Mirror syndrome is a rare disease associated with high fetal mortality of up to 67.2%. It is thought to be underdiagnosed and is often associated with preeclampsia. Mirror syndrome is characterized by "triple edema": generalized maternal, ... ...

Abstract	Introduction: Mirror syndrome is a rare disease associated with high fetal mortality of up to 67.2%. It is thought to be underdiagnosed and is often associated with preeclampsia. Mirror syndrome is characterized by "triple edema": generalized maternal, placental, and fetal edema. Objective: This comprehensive review aims to thoroughly summarize the existing data and provide a broad update on the topic to help accurate diagnosis and encourage further research. Methods: A comprehensive search of several databases (Ovid MEDLINE(R) and Epub Ahead of Print, In-Process & Other Non-Indexed Citations, and Daily, Ovid EMBASE, Ovid Cochrane Central Register of Controlled Trials, Ovid Cochrane Database of Systematic Reviews, and Scopus) was conducted. Results: The last systematic review of mirror syndrome cases was conducted in 2016 and included 113 patients. Much is still unknown about the pathophysiology of the disease and it remains underdiagnosed. Conclusions and relevance: Mirror syndrome is likely more prevalent than current data suggests for it is often misdiagnosed as pre-eclampsia. The differential of Mirror syndrome should be considered in anomalous presentations of pre-eclampsia as intervention may save the fetus and improve maternal symptoms. It is important to further the study on the pathophysiology of the disease to better understand, diagnose and potentially treat it, to avoid its high morbidity and mortality.
MeSH term(s)	Edema/diagnosis ; Female ; Humans ; Hydrops Fetalis/diagnosis ; Placenta ; Pre-Eclampsia/diagnosis ; Pre-Eclampsia/therapy ; Pregnancy ; Syndrome ; Systematic Reviews as Topic
Language	English
Publishing date	2021-03-15
Publishing country	England
Document type	Journal Article ; Review ; Systematic Review
ZDB-ID	2077261-0
ISSN	1476-4954 ; 1057-0802 ; 1476-7058
ISSN (online)	1476-4954
ISSN	1057-0802 ; 1476-7058
DOI	10.1080/14767058.2020.1844656
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Zs.A 3510: Show issues

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Article ; Online: Innovative Fetal Therapy for a Giant Congenital Pulmonary Airway Malformation with Hydrops.

Klinkner, Denise B / Atwell, Thomas / Teles Abrao Trad, Ayssa / Callstrom, Matthew R / Qureshi, Mohamed Yasir / Bendel Stenzel, Ellen / Schenone, Mauro / Ruano, Rodrigo

Fetal diagnosis and therapy

2022 Volume 49, Issue 5-6, Page(s) 250–255

Abstract: Introduction: Congenital pulmonary airway malformations (CPAMs) complicated by hydrops portend significant morbidity and mortality, with fetal survival estimates less than 10%.: Case presentation: We report successful use of ultrasound-guided ... ...

Abstract	Introduction: Congenital pulmonary airway malformations (CPAMs) complicated by hydrops portend significant morbidity and mortality, with fetal survival estimates less than 10%. Case presentation: We report successful use of ultrasound-guided radiofrequency ablation at 21-week gestation in a hydropic fetus with CPAM, with subsequent resolution of hydrops. Thirty-two-week MRI noted persistent mediastinal shift, and US at 36 weeks and 5 days noted polyhydramnios. Maternal gestational hypertension prompted delivery at 37 weeks, with a cesarean section performed after a failed trial of labor. The infant required CPAP at 100% and weaned to 21%. Tachypnea persisted, and chest CT on day of life 2 demonstrated multiple large cysts in the right lower lobe with anterior pneumothorax. On day of life 3, she successfully underwent a thoracoscopic right lower lobectomy. Adhesions to the chest wall and rib abnormalities were noted. She was extubated to CPAP at the conclusion of the procedure. She was able to wean to 21% on POD2 and transitioned to oral feeds. Her chest tube was removed with resultant ex vacuo pneumothorax noted. She remained asymptomatic and was discharged home on room air POD11. Pathology confirmed a type 1 CPAM. Conclusion: In utero radiofrequency ablation may be an adjunct to the management of large CPAM.
MeSH term(s)	Cesarean Section ; Cystic Adenomatoid Malformation of Lung, Congenital/complications ; Cystic Adenomatoid Malformation of Lung, Congenital/diagnostic imaging ; Cystic Adenomatoid Malformation of Lung, Congenital/surgery ; Edema ; Female ; Fetal Therapies ; Fetus/surgery ; Humans ; Hydrops Fetalis/diagnostic imaging ; Hydrops Fetalis/surgery ; Infant ; Pneumothorax/diagnostic imaging ; Pneumothorax/surgery ; Pregnancy
Language	English
Publishing date	2022-04-29
Publishing country	Switzerland
Document type	Case Reports
ZDB-ID	1066460-9
ISSN	1421-9964 ; 1015-3837
ISSN (online)	1421-9964
ISSN	1015-3837
DOI	10.1159/000521690
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Zs.A 2146: Show issues

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Article ; Online: Is there a role for fetal interventions in gastroschisis management? - An updated comprehensive review.

Willborg, Brooke E / Ibirogba, Eniola R / Trad, Ayssa Teles Abrao / Sbragia, Lourenço / Potter, Dean / Ruano, Rodrigo

Prenatal diagnosis

2020 Volume 41, Issue 1, Page(s) 159–176

Abstract: We conducted a comprehensive evidence-based review on the epidemiology and current standard of care of gastroschisis management as well as the pathophysiology, rationale and feasibility of fetal therapy as a viable alternative. Gastroschisis is a ... ...

Abstract	We conducted a comprehensive evidence-based review on the epidemiology and current standard of care of gastroschisis management as well as the pathophysiology, rationale and feasibility of fetal therapy as a viable alternative. Gastroschisis is a periumbilical abdominal wall defect characterized by abdominal viscera herniation in utero. It affects 4 in 10 000 live births, but the prevalence has steadily increased in recent years. Gastroschisis is typically diagnosed on routine second-trimester ultrasound. The overall prognosis is favorable, but complex gastroschisis, which accounts for about 10% to 15% of cases, is associated with a higher mortality, significant disease burden and higher healthcare costs due to long- and short-term complications. The current standard of care has yet to be established but generally involves continued fetal surveillance and multidisciplinary perinatal care. Postnatal surgical repair is achieved with primary closure, staged silo closure or sutureless repair. Experimental animal studies have demonstrated the feasibility of in utero closure, antiinflammatory therapy and prenatal regenerative therapy. However, reports of early preterm delivery and amnioinfusion trials have failed to show any benefit in humans. Further experimental studies and human trials are necessary to demonstrate the potential benefit of fetal therapy in gastroschisis.
MeSH term(s)	Animals ; Fetal Therapies ; Gastroschisis/surgery ; Humans
Language	English
Publishing date	2020-11-01
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	82031-3
ISSN	1097-0223 ; 0197-3851
ISSN (online)	1097-0223
ISSN	0197-3851
DOI	10.1002/pd.5820
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Zs.A 1625: Show issues

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Article ; Online: Interventional resealing of preterm premature rupture of the membranes: a systematic review and meta-analysis.

Ibirogba, Eniola R / Shazly, Sherif A / Narang, Kavita / Wahood, Waseem / Trad, Ayssa Teles Abrao / Tsimis, Michael E / Ruano, Rodrigo

2021 Volume 35, Issue 25, Page(s) 5978–5992

Abstract: Objective: To compare the effectiveness and outcomes of interventional resealing of membranes, "amniopatch" for spontaneous vs. iatrogenic preterm premature rupture of the membranes (sPPROM and iPPROM).: Methods: We performed a systematic review of ... ...

Abstract	Objective: To compare the effectiveness and outcomes of interventional resealing of membranes, "amniopatch" for spontaneous vs. iatrogenic preterm premature rupture of the membranes (sPPROM and iPPROM). Methods: We performed a systematic review of literature involving an electronic search of the following databases: Ovid MEDLINE(R) and Epub Ahead of Print, In-Process and Other Non-Indexed Citations, Ovid MEDLINE(R) Daily, Ovid EMBASE, Ovid Cochrane Central Register of Controlled Trials, and Scopus. An indirect meta-analysis was then performed to compare the obstetric, maternal, fetal, and neonatal outcomes of amniopatch between the sPPROM and iPPROM groups. Results: The mean gestational age (GA) at the time rupture was 17.8 ± 1.8 and 25.2 ± 3.8 weeks for iPPROM and sPPROM, respectively, Conclusions: Amniopatch appears to be a feasible and safe procedure for PPROM treatment. Further research is warranted to investigate the effectiveness of this procedure and establish a standardized criterion for the appropriate selection of patients that could benefit from this intervention.
MeSH term(s)	Pregnancy ; Infant, Newborn ; Female ; Humans ; Infant ; Fetal Membranes, Premature Rupture/epidemiology ; Fetal Membranes, Premature Rupture/therapy ; Fetal Membranes, Premature Rupture/etiology ; Gestational Age
Language	English
Publishing date	2021-08-16
Publishing country	England
Document type	Meta-Analysis ; Systematic Review ; Journal Article
ZDB-ID	2077261-0
ISSN	1476-4954 ; 1057-0802 ; 1476-7058
ISSN (online)	1476-4954
ISSN	1057-0802 ; 1476-7058
DOI	10.1080/14767058.2021.1903858
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Article ; Online: Impact of enhanced recovery implementation in women undergoing abdominal sacrocolpopexy.

Trad, Ayssa Teles Abrao / Tamhane, Prajakta / Weaver, Amy L / Baker, Mary V / Visscher, Sue L / Borah, Bijan J / Kalogera, Eleftheria / Gebhart, John B / Trabuco, Emanuel C

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics

2022 Volume 159, Issue 3, Page(s) 727–734

Abstract: Objective: To assess the effect of Enhanced Recovery After Surgery (ERAS) with and without liposomal bupivacaine (LB) on opioid use, hospital length of stay (LOS), costs, and morbidity of women undergoing sacrocolpopexy.: Methods: Retrospective ... ...

Abstract	Objective: To assess the effect of Enhanced Recovery After Surgery (ERAS) with and without liposomal bupivacaine (LB) on opioid use, hospital length of stay (LOS), costs, and morbidity of women undergoing sacrocolpopexy. Methods: Retrospective cohort of women who underwent abdominal sacrocolpopexy between April 1, 2009 and November 30, 2017. Costs for relevant healthcare services were determined by assigning 2017 charges multiplied by 2017 Medicare Cost Report's cost to charge ratios. Outcomes were compared among periods with multivariable regression models adjusted for age, American Society of Anesthesiologists score, and concurrent hysterectomy and posterior repair. Results: Patients were subdivided into pre-ERAS (G1, n = 128), post-ERAS (G2, n = 83), and post-ERAS plus LB (G3, n = 91). The proportion of patients needing opioids during postoperative days 0-2 was significantly less for G3 (75.8%) compared with G1 (97.7%) and G2 (92.8%); P < 0.001). The median morphine equivalent units (MEU) with interquartile ranges, mean LOS, and adjusted mean standardized costs were significantly lower in G3 compared with the other two groups (35 [20-75] vs. 67 [31-109], and 60 [30-122] MEUs; 1.8 vs. 2.3 vs. 2.9 days; and $2391, $2975, and $3844, for G3, G2, and G1, respectively; P < 0.001). Conclusion: Implementation of an ERAS pathway led to significant decreases in opioid use, LOS, and costs. Supplementation with LB further improved these measures.
MeSH term(s)	Humans ; Female ; Aged ; United States ; Analgesics, Opioid/therapeutic use ; Retrospective Studies ; Medicare ; Enhanced Recovery After Surgery ; Length of Stay ; Pain, Postoperative
Chemical Substances	Analgesics, Opioid
Language	English
Publishing date	2022-06-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	80149-5
ISSN	1879-3479 ; 0020-7292
ISSN (online)	1879-3479
ISSN	0020-7292
DOI	10.1002/ijgo.14279
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Zs.A 355: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: Complications and outcomes of SARS-CoV-2 in pregnancy: where and what is the evidence?

Teles Abrao Trad, Ayssa / Ibirogba, Eniola R / Elrefaei, Amro / Narang, Kavita / Tonni, Gabriele / Picone, Olivier / Suy, Anna / Carreras Moratonas, Elena / Kilby, Mark D / Ruano, Rodrigo

Hypertension in pregnancy

2020 Volume 39, Issue 3, Page(s) 361–369

Abstract: Objectives: To add to the growing evidence on SARS-CoV-2 infection during pregnancy, so as to better inform clinical decision making and optimize patient outcomes.: Methods: A systematic search of relevant databases was perfomed on 25 March 2020 and ... ...

Abstract	Objectives: To add to the growing evidence on SARS-CoV-2 infection during pregnancy, so as to better inform clinical decision making and optimize patient outcomes. Methods: A systematic search of relevant databases was perfomed on 25 March 2020 and a repeat search, on 10 April 2020. Reports of pregnant patients with SARS-CoV-2 infection at any time during their pregnancy were reviewed and summarized . Results: We summarized the outcomes of a total of 155 pregnant women and 118 neonates. The evidence suggests a similar rate of severe COVID-19 cases in pregnant women and the general population. The frequency of cesarean deliveries is high, against guidelines recommendations. Conclusion: Limited data on COVID-19 during preganacy, associated with a wide variation in the methodology make accurate data interpretation difficult.
MeSH term(s)	Betacoronavirus ; COVID-19 ; Cesarean Section/statistics & numerical data ; Coronavirus Infections/complications ; Coronavirus Infections/diagnosis ; Coronavirus Infections/therapy ; Female ; Humans ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/therapy ; Pregnancy ; Pregnancy Complications, Infectious/diagnosis ; Pregnancy Complications, Infectious/therapy ; Prognosis ; SARS-CoV-2 ; Severity of Illness Index
Keywords	covid19
Language	English
Publishing date	2020-05-26
Publishing country	England
Document type	Journal Article ; Systematic Review
ZDB-ID	1151886-8
ISSN	1525-6065 ; 1064-1955
ISSN (online)	1525-6065
ISSN	1064-1955
DOI	10.1080/10641955.2020.1769645
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Article ; Online: SARS-CoV-2 in Pregnancy

Trad, Ayssa Teles Abrao / Ibirogba, Eniola R. / Elrefaei, Amro / Narang, Kavita / Tonni, Gabriele / Picone, Olivier / Suy, Anna / Carreras, Elena / Kilby, Mark D. / Ruano, Rodrigo

SSRN Electronic Journal ; ISSN 1556-5068

Where and What Is the Evidence?

2020

Keywords	covid19
Language	English
Publisher	Elsevier BV
Publishing country	us
Document type	Article ; Online
DOI	10.2139/ssrn.3576828
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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