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Article ; Online: Comparison of Ba-Hao burn ointment gauze and petrolatum gauze in split graft donor site healing: A randomized, prospective, and self-control study.

Liu, Wen-Jing / Qian, Han-Ying / Zhang, Yuan-Yuan / Qiu, Le / Wang, Fei / Chen, Xu-Lin

Health science reports

2024 Volume 7, Issue 4, Page(s) e1988

Abstract: ... up of split-skin graft donor sites treated with Ba-Hao burn ointment (BHBO) gauze, a compound ...

Abstract	Background and aims: To assess patient comfort, wound healing, and scarring at the 6-month follow-up of split-skin graft donor sites treated with Ba-Hao burn ointment (BHBO) gauze, a compound preparation of traditional Chinese medicine since 1970s, compared with petrolatum gauze. Methods: Thirty patients admitted to the Department of Burns of the First Affiliated Hospital of Anhui Medical University between September 2021 and September 2022 participated in this randomized, prospective, self-control clinical study. After harvesting the split skin, donor sites were divided into two parts along the midline. BHBO gauze was applied to half of the donor wounds, and petrolatum gauze was applied to the other half. The wound healing time, pain scores on the postoperative Days 3, 6, and 9, and Vancouver Scar Scale (VSS) score at the 6-month follow-up were assessed. Results: The wound healing time was significantly shorter in the BHBO group than in the control group (10.07 ± 1.48 days vs. 11.50 ± 1.74 days, Conclusion: BHBO resulted in faster donor-site healing, reduced postoperative pain, and improved scar quality at the 6-month follow-up than petrolatum gauze alone.
Language	English
Publishing date	2024-04-02
Publishing country	United States
Document type	Journal Article
ISSN	2398-8835
ISSN (online)	2398-8835
DOI	10.1002/hsr2.1988
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Diversity of the Hydroxylamine Oxidoreductase (HAO) Gene and Its Enzyme Active Site in Agricultural Field Soils.

Ohbayashi, Tsubasa / Wang, Yong / Aoyagi, Luciano Nobuhiro / Hara, Shintaro / Tago, Kanako / Hayatsu, Masahito

Microbes and environments

2023 Volume 38, Issue 4

Abstract: Nitrification is a key process in the biogeochemical nitrogen cycle and a major emission source of the greenhouse gas nitrous oxide ( ... ...

Abstract	Nitrification is a key process in the biogeochemical nitrogen cycle and a major emission source of the greenhouse gas nitrous oxide (N
MeSH term(s)	Archaea/genetics ; Soil/chemistry ; Ammonia ; Hydroxylamine ; Catalytic Domain ; Bacteria/genetics ; Nitrification ; Oxidation-Reduction ; Betaproteobacteria ; Hydroxylamines/pharmacology ; Soil Microbiology ; Phylogeny
Chemical Substances	hydroxylamine dehydrogenase (EC 1.7.2.6) ; Soil ; Ammonia (7664-41-7) ; Hydroxylamine (2FP81O2L9Z) ; Hydroxylamines
Language	English
Publishing date	2023-12-11
Publishing country	Japan
Document type	Journal Article
ISSN	1347-4405
ISSN (online)	1347-4405
DOI	10.1264/jsme2.ME23068
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Pan-Genomic and Transcriptomic Analyses of Marine Pseudoalteromonas agarivorans Hao 2018 Revealed Its Genomic and Metabolic Features

Yuhao Jv / Chenxiang Xi / Yanqiu Zhao / Wei Wang / Yiling Zhang / Kai Liu / Wenlin Liu / Kai Shan / Chunlei Wang / Ruiwen Cao / Cunxi Dai / Yiting Jv / Wenxing Zhu / Haiyong Wang / Qiuxia He / Lujiang Hao

Marine Drugs, Vol 20, Iss 248, p

2022 Volume 248

Abstract: The genomic and carbohydrate metabolic features of Pseudoalteromonas agarivorans Hao 2018 ( P ... agarivorans Hao 2018) were investigated through pan-genomic and transcriptomic analyses, and key enzyme genes ... with the stationary phase (24 h), strain P. agarivorans Hao 2018 had upregulated expression of genes related ...

Abstract	The genomic and carbohydrate metabolic features of Pseudoalteromonas agarivorans Hao 2018 ( P. agarivorans Hao 2018) were investigated through pan-genomic and transcriptomic analyses, and key enzyme genes that may encode the process involved in its extracellular polysaccharide synthesis were screened. The pan-genome of the P. agarivorans strains consists of a core-genome containing 2331 genes, an accessory-genome containing 956 genes, and a unique-genome containing 1519 genes. Clusters of Orthologous Groups analyses showed that P. agarivorans harbors strain-specifically diverse metabolisms, probably representing high evolutionary genome changes. The Kyoto Encyclopedia of Genes and Genomes and reconstructed carbohydrate metabolic pathways displayed that P. agarivorans strains can utilize a variety of carbohydrates, such as d -glucose, d -fructose, and d -lactose. Analyses of differentially expressed genes showed that compared with the stationary phase (24 h), strain P. agarivorans Hao 2018 had upregulated expression of genes related to the synthesis of extracellular polysaccharides in the logarithmic growth phase (2 h), and that the expression of these genes affected extracellular polysaccharide transport, nucleotide sugar synthesis, and glycosyltransferase synthesis. This is the first investigation of the genomic and metabolic features of P. agarivorans through pan-genomic and transcriptomic analyses, and these intriguing discoveries provide the possibility to produce novel marine drug lead compounds with high biological activity.
Keywords	Pseudoalteromonas agarivorans ; pan-genome ; genomic and metabolic features ; KEGG analysis ; transcriptome analysis ; Biology (General) ; QH301-705.5
Subject code	570
Language	English
Publishing date	2022-03-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Genome sequence and transcriptomic profiles of a marine bacterium, Pseudoalteromonas agarivorans Hao 2018.

Shan, Kai / Wang, Chunlei / Liu, Wenlin / Liu, Kai / Jia, Baolei / Hao, Lujiang

Scientific data

2019 Volume 6, Issue 1, Page(s) 10

Abstract: ... genome sequence of Pseudoalteromonas agarivorans Hao 2018, a strain isolated from an abalone breeding environment ... agarivorans Hao 2018. Researchers studying the evolution, environmental adaptations and biotechnological ...

Abstract	Members of the marine genus Pseudoalteromonas have attracted great interest because of their ability to produce a large number of biologically active substances. Here, we report the complete genome sequence of Pseudoalteromonas agarivorans Hao 2018, a strain isolated from an abalone breeding environment, using second-generation Illumina and third-generation PacBio sequencing technologies. Illumina sequencing offers high quality and short reads, while PacBio technology generates long reads. The scaffolds of the two platforms were assembled to yield a complete genome sequence that included two circular chromosomes and one circular plasmid. Transcriptomic data for Pseudoalteromonas were not available. We therefore collected comprehensive RNA-seq data using Illumina sequencing technology from a fermentation culture of P. agarivorans Hao 2018. Researchers studying the evolution, environmental adaptations and biotechnological applications of Pseudoalteromonas may benefit from our genomic and transcriptomic data to analyze the function and expression of genes of interest.
MeSH term(s)	Genome, Bacterial ; Genomics ; Pseudoalteromonas/genetics ; Transcriptome
Language	English
Publishing date	2019-03-27
Publishing country	England
Document type	Dataset ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2775191-0
ISSN	2052-4463 ; 2052-4463
ISSN (online)	2052-4463
ISSN	2052-4463
DOI	10.1038/s41597-019-0012-y
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Toxicological evaluation of aqueous extract of the traditional Chinese formula Qing Hao Gan Cao.

Li, Yongchun / Zhang, Hui / Chen, Shanshan / Zhao, Liutao / Wu, Jie / Li, Pan / Wu, Guanlian / Wang, Qing / Wu, Chunli / Xu, Hongde

Toxicology research

2021 Volume 10, Issue 2, Page(s) 183–191

Abstract: Qing Hao Gan Cao ...

Abstract	Qing Hao Gan Cao
Language	English
Publishing date	2021-02-15
Publishing country	England
Document type	Journal Article
ZDB-ID	2684701-2
ISSN	2045-4538 ; 2045-452X
ISSN (online)	2045-4538
ISSN	2045-452X
DOI	10.1093/toxres/tfaa103
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Article: Effect of Different Initial Fermentation pH on Exopolysaccharides Produced by Pseudoalteromonas agarivorans Hao 2018 and Identification of Key Genes Involved in Exopolysaccharide Synthesis via Transcriptome Analysis

Ju, Yuhao / Shan, Kai / Liu, Wenlin / Xi, Chenxiang / Zhang, Yiling / Wang, Wei / Wang, Chunlei / Cao, Ruiwen / Zhu, Wenxing / Wang, Haiyong / Zhao, Yanqiu / Hao, Lujiang

Marine drugs. 2022 Jan. 20, v. 20, no. 2

2022

Abstract: ... monosaccharide composition, and antioxidant activity of the EPSs of Pseudoalteromonas agarivorans Hao 2018 ... In addition, the transcriptome sequence of P. agarivorans Hao 2018 under different initial fermentation pH ...

Abstract	Exopolysaccharides (EPSs) are carbohydrate polymers produced and secreted by microorganisms. In a changing marine environment, EPS secretion can reduce damage from external environmental disturbances to microorganisms. Meanwhile, EPSs have promising application prospects in the fields of food, cosmetics, and pharmaceuticals. Changes in external environmental pH have been shown to affect the synthesis of EPSs in microorganisms. In this study, we analyzed the effects of different initial fermentation pHs on the production, monosaccharide composition, and antioxidant activity of the EPSs of Pseudoalteromonas agarivorans Hao 2018. In addition, the transcriptome sequence of P. agarivorans Hao 2018 under different initial fermentation pH levels was determined. GO and KEGG analyses showed that the differentially expressed genes were concentrated in the two-component regulatory system and bacterial chemotaxis pathways. We further identified the expression of key genes involved in EPS synthesis during pH changes. In particular, the expression of genes encoding the glucose/galactose MFS transporter, phosphomannomutase, and mannose-1-phosphate guanylyltransferase was upregulated when the environmental pH increased, thus promoting EPS synthesis. This study not only contributes to elucidating the environmental adaptation mechanisms of P. agarivorans, but also provides important theoretical guidance for the directed development of new products using biologically active polysaccharides.
Keywords	Pseudoalteromonas ; antioxidant activity ; chemotaxis ; cosmetics ; drugs ; exopolysaccharides ; fermentation ; galactose ; gene expression regulation ; glucose ; marine environment ; pH ; phosphomannomutase ; secretion ; transcriptome ; transcriptomics
Language	English
Dates of publication	2022-0120
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article
ZDB-ID	2175190-0
ISSN	1660-3397
ISSN	1660-3397
DOI	10.3390/md20020089
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Effect of Different Initial Fermentation pH on Exopolysaccharides Produced by Pseudoalteromonas agarivorans Hao 2018 and Identification of Key Genes Involved in Exopolysaccharide Synthesis via Transcriptome Analysis

Yuhao Ju / Kai Shan / Wenlin Liu / Chenxiang Xi / Yiling Zhang / Wei Wang / Chunlei Wang / Ruiwen Cao / Wenxing Zhu / Haiyong Wang / Yanqiu Zhao / Lujiang Hao

Marine Drugs, Vol 20, Iss 89, p

2022 Volume 89

Abstract	Exopolysaccharides (EPSs) are carbohydrate polymers produced and secreted by microorganisms. In a changing marine environment, EPS secretion can reduce damage from external environmental disturbances to microorganisms. Meanwhile, EPSs have promising application prospects in the fields of food, cosmetics, and pharmaceuticals. Changes in external environmental pH have been shown to affect the synthesis of EPSs in microorganisms. In this study, we analyzed the effects of different initial fermentation pHs on the production, monosaccharide composition, and antioxidant activity of the EPSs of Pseudoalteromonas agarivorans Hao 2018. In addition, the transcriptome sequence of P. agarivorans Hao 2018 under different initial fermentation pH levels was determined. GO and KEGG analyses showed that the differentially expressed genes were concentrated in the two-component regulatory system and bacterial chemotaxis pathways. We further identified the expression of key genes involved in EPS synthesis during pH changes. In particular, the expression of genes encoding the glucose/galactose MFS transporter, phosphomannomutase, and mannose-1-phosphate guanylyltransferase was upregulated when the environmental pH increased, thus promoting EPS synthesis. This study not only contributes to elucidating the environmental adaptation mechanisms of P. agarivorans , but also provides important theoretical guidance for the directed development of new products using biologically active polysaccharides.
Keywords	marine bacteria ; structural analysis ; transcriptome sequence ; KEGG analysis ; GO analysis ; Biology (General) ; QH301-705.5
Language	English
Publishing date	2022-01-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Genome sequence and transcriptomic profiles of a marine bacterium, Pseudoalteromonas agarivorans Hao 2018

Kai Shan / Chunlei Wang / Wenlin Liu / Kai Liu / Baolei Jia / Lujiang Hao

Scientific Data, Vol 6, Iss 1, Pp 1-

2019 Volume 7

Abstract: Design Type(s)transcription profiling design • source-based data analysis objectiveMeasurement Type(s)whole genome sequencing assay • transcription profiling assayTechnology Type(s)DNA sequencing • RNA sequencingFactor Type(s)Sample Characteristic(s) ... ...

Abstract	Design Type(s)transcription profiling design • source-based data analysis objectiveMeasurement Type(s)whole genome sequencing assay • transcription profiling assayTechnology Type(s)DNA sequencing • RNA sequencingFactor Type(s)Sample Characteristic(s)Pseudoalteromonas agarivorans • ocean biome Machine-accessible metadata file describing the reported data (ISA-Tab format)
Keywords	Science ; Q
Language	English
Publishing date	2019-03-01T00:00:00Z
Publisher	Nature Publishing Group
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Correction for Hao et al., Infection and propagation of human rhinovirus C in human airway epithelial cells.

Hao, Weidong / Bernard, Katie / Patel, Nita / Ulbrandt, Nancy / Feng, Hui / Svabek, Catherine / Wilson, Susan / Stracener, Christina / Wang, Kathy / Suzich, JoAnn / Blair, Wade / Zhu, Qing

Journal of virology

2015 Volume 89, Issue 7, Page(s) 4041

Language	English
Publishing date	2015-04
Publishing country	United States
Document type	Published Erratum
ZDB-ID	80174-4
ISSN	1098-5514 ; 0022-538X
ISSN (online)	1098-5514
ISSN	0022-538X
DOI	10.1128/JVI.00119-15
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Book: Youyou yu qing hao su

Wang, Manyuan

2015

Author's details	Wang Manyuan bian zhu
MeSH term(s)	Biomedical Research ; Artemisinins/pharmacology ; Malaria/drug therapy
Keywords	China
Language	Chinese
Size	8, 101 pages :, illustrations, portraits
Edition	Di 1 ban.
Document type	Book
ISBN	9787117218917 ; 7117218916
Database	Catalogue of the US National Library of Medicine (NLM)

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