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  1. Article ; Online: Insight into the Antibiotic Resistance of Bacteria Isolated from Popular Aquatic Products Collected in Zhejiang, China.

    Wu, Jiajia / Ye, Fan / Qu, Jiong / Dai, Zhiyuan

    Polish journal of microbiology

    2023  Volume 72, Issue 1, Page(s) 61–67

    Abstract: The present study was aimed to obtain a close insight into the distribution and diversity of antibiotic-resistant bacteria (ARB) and antibiotic-resistance genes (ARGs) among the aquatic products collected in Zhejiang, China. A total of 136 presumptive ... ...

    Abstract The present study was aimed to obtain a close insight into the distribution and diversity of antibiotic-resistant bacteria (ARB) and antibiotic-resistance genes (ARGs) among the aquatic products collected in Zhejiang, China. A total of 136 presumptive ARB picked up from six aquatic samples were classified into 22 genera and 49 species based on the 16S rDNA sequencing.
    MeSH term(s) Humans ; Genes, Bacterial ; Angiotensin Receptor Antagonists ; Angiotensin-Converting Enzyme Inhibitors ; Drug Resistance, Microbial/genetics ; Aeromonas/genetics ; Anti-Bacterial Agents/pharmacology
    Chemical Substances Angiotensin Receptor Antagonists ; Angiotensin-Converting Enzyme Inhibitors ; Anti-Bacterial Agents
    Language English
    Publishing date 2023-03-24
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 2234080-4
    ISSN 2544-4646 ; 1733-1331
    ISSN (online) 2544-4646
    ISSN 1733-1331
    DOI 10.33073/pjm-2023-010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Promote COVID-19 Vaccination for Older Adults in China.

    Zang, Shujie / Zhang, Xu / Qu, Zhiqiang / Chen, Xi / Hou, Zhiyuan

    China CDC weekly

    2022  Volume 4, Issue 37, Page(s) 832–834

    Language English
    Publishing date 2022-09-29
    Publishing country China
    Document type Journal Article
    ISSN 2096-7071
    ISSN (online) 2096-7071
    DOI 10.46234/ccdcw2022.173
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: A novel amidine-based fluorescent probe TPE-4

    Zhang, Mingwei / Sun, Zhiyuan / Sun, Yuanqiang / Zhao, Linping / Yang, Ran / Qu, Lingbo

    Talanta

    2023  Volume 270, Page(s) 125614

    Abstract: An accurate, fast, and simple surfactant detection method is of great significance for monitoring surfactants pollution. Sodium dodecyl sulfate (SDS) is one of the most commonly used anionic surfactants and has been listed as an important monitoring ... ...

    Abstract An accurate, fast, and simple surfactant detection method is of great significance for monitoring surfactants pollution. Sodium dodecyl sulfate (SDS) is one of the most commonly used anionic surfactants and has been listed as an important monitoring pollutant for surfactant residues. Herein, a novel fluorescent probe named TPE-4
    Language English
    Publishing date 2023-12-28
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1500969-5
    ISSN 1873-3573 ; 0039-9140
    ISSN (online) 1873-3573
    ISSN 0039-9140
    DOI 10.1016/j.talanta.2023.125614
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Relationships among Square Dance, Group Cohesion, Perceived Social Support, and Psychological Capital in 2721 Middle-Aged and Older Adults in China.

    Qu, Yujia / Liu, Zhiyuan / Wang, Yan / Chang, Lei / Fan, Hongying

    Healthcare (Basel, Switzerland)

    2023  Volume 11, Issue 14

    Abstract: 1) Background: Aging is a global phenomenon, and China's aging is extensive and rapid and already at the middle to upper level worldwide. Promoting social interaction and increasing positive psychological qualities in individuals are key components in ... ...

    Abstract (1) Background: Aging is a global phenomenon, and China's aging is extensive and rapid and already at the middle to upper level worldwide. Promoting social interaction and increasing positive psychological qualities in individuals are key components in helping people adapt to the physical and mental changes of the aging process. Among them, how middle-aged and older adults improve their physical and mental health through physical activity is of great concern. (2) Methods: This study measured the physical activity of 2721 middle-aged and elderly square dance participants across China, and structural equation modeling was applied to explore the relationship between square dance exercise and group cohesion as well as the role of perceived social support and psychological capital. (3) Results: The results showed that (a) square dance exercise positively predicts group cohesion among middle-aged and older adults. (b) Perceived social support and psychological capital mediate the relationship between square dance exercise and group cohesion, and the mediating role consists of three pathways: perceived social support alone, psychological capital alone, and perceived social support-psychological capital chain mediation. (c) The mediating effect of psychological capital alone is greater than the mediating effect of perceived social support alone and the mediating effect of the perceived social support-psychological capital chain. (4) Conclusions: This study provides support for the theory and practice of square dance exercise and intervention guidance for increasing positive psychological qualities and group dynamic levels in middle-aged and older adults.
    Language English
    Publishing date 2023-07-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2721009-1
    ISSN 2227-9032
    ISSN 2227-9032
    DOI 10.3390/healthcare11142025
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Influence of Surfacing Fe-Based Alloy Layers on Wire Arc Additive Manufactured Ni-Based Superalloys Material on Its Microstructure and Wear Properties.

    Yu, Yingyan / Qu, Zhiyuan / Zhang, Jiansheng / Zhou, Jie

    Materials (Basel, Switzerland)

    2022  Volume 15, Issue 17

    Abstract: Wire arc additively manufactured (WAAM) Ni-based materials have good properties but are costly and hard to cut, leading to difficulties in machining after welding and wasting the materials. To overcome these shortcomings, this work proposes a method of ... ...

    Abstract Wire arc additively manufactured (WAAM) Ni-based materials have good properties but are costly and hard to cut, leading to difficulties in machining after welding and wasting the materials. To overcome these shortcomings, this work proposes a method of surfacing Fe-based alloy layers on WAAM Ni-based material. The effect of this method on the microstructure and wear properties of WAAM Ni-based materials is discussed. In this work, a Fe-based alloy (JX103) was welded as the last layers of the WAAM Ni-based superalloy (JX201) material. The hardness, microstructure, and wear behavior of the material with different residual Fe-based materials were tested and analyzed. Our results indicate that the surface hardness was smoothly increased from HV350 to HV400 by overlaying Fe-based alloy layers. Microstructure analysis shows that γ-Fe gradually disappears, and the carbide form changes from WAAM Ni-based superalloys to Fe-based alloys. In the fusion boundary, the occurrence of cellular dendritic growth, a type -Ⅱ boundary, and low dilution indicate good crack resistance and good connection performance between these two materials. The wear test showed that the wear resistance of JX201 was decreased by changing the last layer to JX103. However, as the residual thickness of JX103 decreased, the influence gradually reduced. Meanwhile, the wear mechanism changed from severe abrasive and adhesive wear to light abrasive wear. When the thickness is less than 0.5 mm, the wear weight per minute is at the same level as the sample without JX103.
    Language English
    Publishing date 2022-08-31
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma15176020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Highly Sensitive and Quantitative Magnetic Nanoparticle-Based Lateral Flow Immunoassay with an Atomic Magnetometer.

    Wang, Boyu / Peng, Tao / Jiang, Zhiyuan / Xu, Jinxin / Qu, Jifeng / Dai, Xinhua

    ACS sensors

    2023  Volume 8, Issue 12, Page(s) 4512–4520

    Abstract: Lateral flow immunoassay (LFIA) is a simple point-of-care method for detecting various analytes. However, the lack of test result precision and poor quantification are the main bottlenecks of LFIA. Although magnetic nanoparticles (MNPs) have gained ... ...

    Abstract Lateral flow immunoassay (LFIA) is a simple point-of-care method for detecting various analytes. However, the lack of test result precision and poor quantification are the main bottlenecks of LFIA. Although magnetic nanoparticles (MNPs) have gained prominence as potent labels in LIFA, the quantitative detection method for trace biomarkers remains to be improved. Here, we propose a promising real-time biosensing platform based on a highly sensitive atomic magnetometer to fulfill the quantitative detection of MNP-based lateral flow immunochromatographic assays. The strategy entails obtaining the residual flux density component spectrum by continuously and linearly scanning the trace MNP label and then resolving the magnetization and quantity from the spectrum. Moreover, we exploit the theoretical model of the magnetic dipole to verify the method's reliability. Regarding carcinoembryonic antigen detection, the atomic magnetometer exhibits a low detection limit of ∼0.01 ng mL
    MeSH term(s) Magnetite Nanoparticles/chemistry ; Reproducibility of Results ; Limit of Detection ; Magnetics ; Immunoassay/methods
    Chemical Substances Magnetite Nanoparticles
    Language English
    Publishing date 2023-11-20
    Publishing country United States
    Document type Journal Article
    ISSN 2379-3694
    ISSN (online) 2379-3694
    DOI 10.1021/acssensors.3c01028
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Current Knowledge about Headaches Attributed to Ischemic Stroke: Changes from Structure to Function.

    Xie, Xinxin / Zhang, Yi / Kong, Qianqian / Huang, Hao / Yu, Zhiyuan / Luo, Xiang / Qu, Wensheng

    Brain sciences

    2023  Volume 13, Issue 7

    Abstract: Headaches are common after ischemic stroke (IS). Unlike primary headaches, headaches attributed to IS have specific clinical features. This review describes the epidemiology, clinical characteristics, risk factors, and influence of IS headaches. Previous ...

    Abstract Headaches are common after ischemic stroke (IS). Unlike primary headaches, headaches attributed to IS have specific clinical features. This review describes the epidemiology, clinical characteristics, risk factors, and influence of IS headaches. Previous reports were summarized to show the correlations between headaches and structural lesions in the cerebral cortex, subcortical white matter, deep gray matter nuclei, brainstem, and cerebellum. However, the substantial heterogeneity of IS, subjective evaluations of headaches, and inadequate cohort studies make it difficult to explore the pathophysiology of headaches attributed to IS. In our recommendation, favorable imaging techniques, such as magnetic resonance imaging and positron emission tomography, may provide new insights into mechanical studies of IS headaches from structure to function. It may also be helpful to extend the research field by targeting several shared signal transducers between headaches and IS. These markers might be neuropeptides, vasoactive substances, ion channels, or electrophysiologic changes.
    Language English
    Publishing date 2023-07-23
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2651993-8
    ISSN 2076-3425
    ISSN 2076-3425
    DOI 10.3390/brainsci13071117
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  8. Article ; Online: [Corrigendum] MicroRNA‑133b targets TGFβ receptor I to inhibit TGF‑β‑induced epithelial‑to‑mesenchymal transition and metastasis by suppressing the TGF‑β/SMAD pathway in breast cancer.

    Wang, Shengjie / Huang, Mingliang / Wang, Zichen / Wang, Wan / Zhang, Zhiyuan / Qu, Shuting / Liu, Chun

    International journal of oncology

    2023  Volume 63, Issue 1

    Abstract: Following the publication of the above article, an interested reader drew to the authors' attention that, for the MCF‑7 cell migration assays shown in Fig. 3C on p. 1105, the representative images selected for the 'TGF‑β+ / miR‑NC' and 'TGF‑β1‑ / miR‑NC' ...

    Abstract Following the publication of the above article, an interested reader drew to the authors' attention that, for the MCF‑7 cell migration assays shown in Fig. 3C on p. 1105, the representative images selected for the 'TGF‑β+ / miR‑NC' and 'TGF‑β1‑ / miR‑NC' experiments were found to be overlapping, such that the data appeared to have been derived from the same original source. After having consulted their original data, the authors noted that the error had arisen during the process of assembling this figure, and the data chosen for the 'TGF‑β+ / miR‑NC' panel had been selected incorrectly. The revised version of Fig. 3 is shown on the next page. The authors regret that these errors went unnoticed prior to the publication of this article, and thank the Editor of
    Language English
    Publishing date 2023-06-09
    Publishing country Greece
    Document type Published Erratum
    ZDB-ID 1154403-x
    ISSN 1791-2423 ; 1019-6439
    ISSN (online) 1791-2423
    ISSN 1019-6439
    DOI 10.3892/ijo.2023.5531
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 3690: Show issues Location:
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  9. Article ; Online: Gradient matters via filament diameter-adjustable 3D printing.

    Qu, Huawei / Gao, Chongjian / Liu, Kaizheng / Fu, Hongya / Liu, Zhiyuan / Kouwer, Paul H J / Han, Zhenyu / Ruan, Changshun

    Nature communications

    2024  Volume 15, Issue 1, Page(s) 2930

    Abstract: Gradient matters with hierarchical structures endow the natural world with excellent integrity and diversity. Currently, direct ink writing 3D printing is attracting tremendous interest, and has been used to explore the fabrication of 1D and 2D ... ...

    Abstract Gradient matters with hierarchical structures endow the natural world with excellent integrity and diversity. Currently, direct ink writing 3D printing is attracting tremendous interest, and has been used to explore the fabrication of 1D and 2D hierarchical structures by adjusting the diameter, spacing, and angle between filaments. However, it is difficult to generate complex 3D gradient matters owing to the inherent limitations of existing methods in terms of available gradient dimension, gradient resolution, and shape fidelity. Here, we report a filament diameter-adjustable 3D printing strategy that enables conventional extrusion 3D printers to produce 1D, 2D, and 3D gradient matters with tunable heterogeneous structures by continuously varying the volume of deposited ink on the printing trajectory. In detail, we develop diameter-programmable filaments by customizing the printing velocity and height. To achieve high shape fidelity, we specially add supporting layers at needed locations. Finally, we showcase multi-disciplinary applications of our strategy in creating horizontal, radial, and axial gradient structures, letter-embedded structures, metastructures, tissue-mimicking scaffolds, flexible electronics, and time-driven devices. By showing the potential of this strategy, we anticipate that it could be easily extended to a variety of filament-based additive manufacturing technologies and facilitate the development of functionally graded structures.
    Language English
    Publishing date 2024-04-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-024-47360-y
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  10. Article ; Online: Uplifting Anti-tumor Immunotherapy with Lymph Node-targeted and Ratio-controlled Co-delivery of Tumor Cell Lysate and Adjuvant.

    Cui, Guanhong / Sun, Yinping / Qu, Liping / Shen, Cui / Sun, Yu / Meng, Fenghua / Zheng, Yiran / Zhong, Zhiyuan

    Advanced healthcare materials

    2024  , Page(s) e2303690

    Abstract: Cancer vaccines provide a potential strategy to cure patients. Their clinical utilization and efficacy is, however, limited by incomplete coverage of tumor neoantigens and unspecific and restricted activation of dendritic cells (DCs). Tumor cell lysates ( ...

    Abstract Cancer vaccines provide a potential strategy to cure patients. Their clinical utilization and efficacy is, however, limited by incomplete coverage of tumor neoantigens and unspecific and restricted activation of dendritic cells (DCs). Tumor cell lysates (TCL) containing a broad spectrum of neoantigens, while are considered ideal in formulating personalized vaccines, induce generally poor antigen presentation and transient anti-tumor immune response. Here, intelligent polymersomal nanovaccines (PNVs) that quantitatively co-load, efficiently co-deliver and responsively co-release TCL and CpG adjuvant to lymph node (LN) DCs are developed to boost antigen presentation and to induce specific and robust anti-tumor immunity. PNVs carrying CpG and OVA (CpG/OVA@PNV) markedly enhanced the maturation, antigen presentation and downstream T cell activation ability of BMDCs and induced strong systemic immune response after tail base injection. Remarkably, PNVs carrying CpG and TCL (CpG/TCL@PNV) cured 85% of B16-F10 melanoma-bearing mice and generated long-lasting anti-cancer immune memory at a low dose, protecting all cured mice from tumor re-challenge. These LN-directed PNVs being highly versatile and straightforward opens a new door for personalized cancer vaccines. This article is protected by copyright. All rights reserved.
    Language English
    Publishing date 2024-03-08
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2649576-4
    ISSN 2192-2659 ; 2192-2640
    ISSN (online) 2192-2659
    ISSN 2192-2640
    DOI 10.1002/adhm.202303690
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6966: Show issues Location:
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