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  1. Book ; Online ; E-Book: Stem cell laboratory techniques

    Subbiah, Suresh Kumar / Higuchi, Akon / Mok, Pooi Ling

    a guide for researchers and students

    2023  

    Author's details edited by Suresh Kumar Subbiah, Akon Higuchi, Pooi Ling Mok
    Keywords Electronic books
    Language English
    Size 1 Online-Ressource (xiv, 225 Seiten), Illustrationen, Diagramme
    Publisher Elsevier Academic Press
    Publishing place London
    Publishing country Great Britain
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT030032264
    ISBN 978-0-12-823730-4 ; 9780128237298 ; 0-12-823730-9 ; 0128237295
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    Full text online

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  2. Article: Editorial: Neurodegenerative eye diseases: Molecular mechanisms of neurogenesis and therapeutic perspectives.

    Mok, Pooi Ling / Catherine, Bastion Mae-Lynn / Subbiah, Suresh Kumar / Higuchi, Akon

    Frontiers in cellular neuroscience

    2022  Volume 16, Page(s) 1060266

    Language English
    Publishing date 2022-10-26
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2452963-1
    ISSN 1662-5102
    ISSN 1662-5102
    DOI 10.3389/fncel.2022.1060266
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9 transfection of guide RNA targeting on

    Teh, Seoh Wei / Elderdery, Abozer / Rampal, Sanjiv / Subbiah, Suresh Kumar / Mok, Pooi Ling

    Contemporary oncology (Poznan, Poland)

    2024  Volume 27, Issue 4, Page(s) 255–262

    Abstract: Introduction: Cutaneous squamous cell carcinoma (SCC) is the second most common form of skin malignancy, representing around 20% of all skin cancers. It is the main cause of death due to non-melanoma skin cancer every year. Metastatic cutaneous SCC is ... ...

    Abstract Introduction: Cutaneous squamous cell carcinoma (SCC) is the second most common form of skin malignancy, representing around 20% of all skin cancers. It is the main cause of death due to non-melanoma skin cancer every year. Metastatic cutaneous SCC is associated with poor prognosis in patients and warrants a more effective and specific approach such as disruption of genes associated with cancer metastasis.
    Material and methods: Matrix metalloproteinases (MMPs) are enzymes involved in cancer progression and are regarded as major oncotargets. Among others, MMP9 plays critical roles in tumour progression, angiogenesis, and invasion of cutaneous SCC. We aimed to determine whether the
    Results: Following CRISPR transfection treatment, the viability (
    Conclusions: Our findings provided direct evidence that MMP9 is important in the viability, proliferation, and metastasis of cutaneous SCC cells. It serves as a positive foundation for future CRISPR-based targeted anti-cancer therapies in treating skin cancer and other forms of malignancies that involve MMPs as the key determinants.
    Language English
    Publishing date 2024-02-21
    Publishing country Poland
    Document type Journal Article
    ISSN 1428-2526
    ISSN 1428-2526
    DOI 10.5114/wo.2023.135364
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Misunderstanding of Leptospirosis.

    Teh, Seoh Wei / Mok, Pooi Ling / Subbiah, Suresh Kumar

    Acta tropica

    2019  Volume 197, Page(s) 105046

    Language English
    Publishing date 2019-05-31
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 210415-5
    ISSN 1873-6254 ; 0001-706X
    ISSN (online) 1873-6254
    ISSN 0001-706X
    DOI 10.1016/j.actatropica.2019.105046
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ud II Zs.136: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
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  5. Article: Syzygium cumini

    Rayzah, Musaed / Elderdery, Abozer Y / Alzerwi, Nasser A N / Alzahrani, Badr / Alsrhani, Abdullah / Alsultan, Afnan / Idrees, Bandar / Rayzah, Fares / Bakhsh, Yaser / Alzahrani, Ahmed M / Subbiah, Suresh K / Mok, Pooi Ling

    Plants (Basel, Switzerland)

    2023  Volume 12, Issue 18

    Abstract: An aqueous extract ... ...

    Abstract An aqueous extract of
    Language English
    Publishing date 2023-09-05
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704341-1
    ISSN 2223-7747
    ISSN 2223-7747
    DOI 10.3390/plants12183174
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: CuO-TiO

    Elderdery, Abozer Y / Alzahrani, Badr / Hamza, Siddiqa M A / Mostafa-Hedeab, Gomaa / Mok, Pooi Ling / Subbiah, Suresh Kumar

    publication RETRACTED

    Bioinorganic chemistry and applications

    2022  Volume 2022, Page(s) 9602725

    Abstract: In this study, cells from human Chronic Myelogenous Leukemia (K562) were cultivated with CuO- ... ...

    Abstract In this study, cells from human Chronic Myelogenous Leukemia (K562) were cultivated with CuO-TiO
    Language English
    Publishing date 2022-09-17
    Publishing country Egypt
    Document type Journal Article ; Retracted Publication
    ZDB-ID 2213020-2
    ISSN 1687-479X ; 1565-3633
    ISSN (online) 1687-479X
    ISSN 1565-3633
    DOI 10.1155/2022/9602725
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Corrigendum: Mitigation of Sodium Iodate-Induced Cytotoxicity in Retinal Pigment Epithelial Cells

    Koh, Avin Ee-Hwan / Subbiah, Suresh Kumar / Farhana, Aisha / Alam, Mohammad Khursheed / Mok, Pooi Ling

    Frontiers in cell and developmental biology

    2021  Volume 9, Page(s) 770837

    Abstract: This corrects the article DOI: 10.3389/fcell.2021.652065.]. ...

    Abstract [This corrects the article DOI: 10.3389/fcell.2021.652065.].
    Language English
    Publishing date 2021-10-04
    Publishing country Switzerland
    Document type Published Erratum
    ZDB-ID 2737824-X
    ISSN 2296-634X
    ISSN 2296-634X
    DOI 10.3389/fcell.2021.770837
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Pluronic-F-127-Passivated SnO

    Alzahrani, Badr / Elderdery, Abozer Y / Alzerwi, Nasser A N / Alsrhani, Abdullah / Alsultan, Afnan / Rayzah, Musaed / Idrees, Bandar / Rayzah, Fares / Baksh, Yaser / Alzahrani, Ahmed M / Subbiah, Suresh K / Mok, Pooi Ling

    Plants (Basel, Switzerland)

    2023  Volume 12, Issue 9

    Abstract: Nanotechnology has emerged as the most popular research topic with revolutionary applications across all scientific disciplines. Tin oxide ( ... ...

    Abstract Nanotechnology has emerged as the most popular research topic with revolutionary applications across all scientific disciplines. Tin oxide (SnO
    Language English
    Publishing date 2023-04-25
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704341-1
    ISSN 2223-7747
    ISSN 2223-7747
    DOI 10.3390/plants12091760
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Synthesis, Characterization, and Antiproliferative Effect of CuO-TiO

    Elderdery, Abozer Y / Alzahrani, Badr / Hamza, Siddiqa M A / Mostafa-Hedeab, Gomaa / Mok, Pooi Ling / Subbiah, Suresh Kumar

    Bioinorganic chemistry and applications

    2022  Volume 2022, Page(s) 1473922

    Abstract: The main aim of this study was to synthesize copper oxide- (CuO-) titanium oxide- ( ... ...

    Abstract The main aim of this study was to synthesize copper oxide- (CuO-) titanium oxide- (TiO
    Language English
    Publishing date 2022-09-26
    Publishing country Egypt
    Document type Journal Article
    ZDB-ID 2213020-2
    ISSN 1687-479X ; 1565-3633
    ISSN (online) 1687-479X
    ISSN 1565-3633
    DOI 10.1155/2022/1473922
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: In silico

    Farhana, Aisha / Kothandan, Sangeetha / Alsrhani, Abdullah / Mok, Pooi Ling / Subbiah, Suresh Kumar / Khan, Yusuf Saleem

    Contrast media & molecular imaging

    2022  Volume 2022, Page(s) 4202623

    Abstract: S100A4 protein overexpression has been reported in different types of cancer and plays a key role by interacting with the tumor suppressor protein Tp53. Single nucleotide polymorphisms (SNP) in S100A4 could directly influence the biomolecular interaction ...

    Abstract S100A4 protein overexpression has been reported in different types of cancer and plays a key role by interacting with the tumor suppressor protein Tp53. Single nucleotide polymorphisms (SNP) in S100A4 could directly influence the biomolecular interaction with the tumor suppressor protein Tp53 due to their aberrant conformations. Hence, the study was designed to predict the deleterious SNP and its effect on the S100A4 protein structure and function. Twenty-one SNP data sets were screened for nonsynonymous mutations and subsequently subjected to deleterious mutation prediction using different computational tools. The screened deleterious mutations were analyzed for their changes in functionality and their interaction with the tumor suppressor protein Tp53 by protein-protein docking analysis. The structural effects were studied using the 3DMissense mutation tool to estimate the solvation energy and torsion angle of the screened mutations on the predicted structures. In our study, 21 deleterious nonsynonymous mutations were screened, including F72V, E74G, L5P, D25E, N65S, A28V, A8D, S20L, L58P, and K26N were found to be remarkably conserved by exhibiting the interaction either with the EF-hand 1 or EF-hand 2 domain. The solvation and torsion values significantly deviated for the mutant-type structures with S20L, N65S, and F72L mutations and showed a marked reduction in their binding affinity with the Tp53 protein. Hence, these deleterious mutations might serve as prospective targets for diagnosing and developing personalized treatments for cancer and other related diseases.
    MeSH term(s) Humans ; Mutation/genetics ; Neoplasms ; Polymorphism, Single Nucleotide/genetics ; S100 Calcium-Binding Protein A4/genetics
    Chemical Substances S100 Calcium-Binding Protein A4 ; S100A4 protein, human (142662-27-9)
    Language English
    Publishing date 2022-07-31
    Publishing country England
    Document type Journal Article
    ZDB-ID 2232678-9
    ISSN 1555-4317 ; 1555-4309
    ISSN (online) 1555-4317
    ISSN 1555-4309
    DOI 10.1155/2022/4202623
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6273: Show issues Location:
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