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  1. Article: The profound heterogeneity of substance use disorders: Implications for treatment development.

    Carroll, Kathleen M

    Current directions in psychological science

    2021  Volume 30, Issue 4, Page(s) 358–364

    Abstract: A single treatment approach will never be sufficient to address the diversity of individuals with substance use disorders (SUDs). SUDs have historically defied definition through simple characterizations or models, and no single characterization has led ... ...

    Abstract A single treatment approach will never be sufficient to address the diversity of individuals with substance use disorders (SUDs). SUDs have historically defied definition through simple characterizations or models, and no single characterization has led to the development of broadly effective interventions. The range of dimensions of heterogeneity among individuals with SUDs, including severity, type of substance, and issues that frequently co-occur underscore that highly tailored approaches are needed. To approach personalized medicine for individuals with SUDs; two major developments are needed. First, given the diversity of individuals with SUDs, multivariate phenotyping approaches are needed to identify the particular features driving addictive processes in any individual. Second, a wider range of interventions that directly target core mechanisms of addiction and the problems that co-occur with them are needed. As clinicians cannot be expected to master the full range of interventions that may target these core processes, developing these so that they can be delivered easily, flexibly, and systematically via technology will facilitate our ability to truly tailor interventions to this highly complex and challenging population. One such technology-delivered intervention, computer-based training for cognitive behavioral therapy (CBT4CBT), is used as an example to illustrate a vision for the future of highly-tailored interventions for individuals with SUDs.
    Language English
    Publishing date 2021-07-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2026362-4
    ISSN 1467-8721 ; 0963-7214
    ISSN (online) 1467-8721
    ISSN 0963-7214
    DOI 10.1177/09637214211026984
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Use Without Consequences? A Commentary on Bonn et al. (2020).

    Carroll, Kathleen M

    Journal of studies on alcohol and drugs

    2020  Volume 81, Issue 5, Page(s) 561

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections ; HIV Infections ; Hepatitis C ; Humans ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2 ; Syndemic
    Keywords covid19
    Language English
    Publishing date 2020-10-07
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2266450-6
    ISSN 1938-4114 ; 1934-2683 ; 1937-1888 ; 0096-882X
    ISSN (online) 1938-4114 ; 1934-2683
    ISSN 1937-1888 ; 0096-882X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  4. Article ; Online: Training in vain?

    Carroll, Kathleen M

    Addiction (Abingdon, England)

    2016  Volume 111, Issue 7, Page(s) 1153–1154

    MeSH term(s) Female ; Humans ; Motivational Interviewing
    Language English
    Publishing date 2016
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 1141051-6
    ISSN 1360-0443 ; 0965-2140
    ISSN (online) 1360-0443
    ISSN 0965-2140
    DOI 10.1111/add.13175
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  5. Article: The Role of Behavioral Interventions in Buprenorphine Maintenance Treatment: A Review.

    Carroll, Kathleen M / Weiss, Roger D

    Focus (American Psychiatric Publishing)

    2019  Volume 17, Issue 2, Page(s) 183–192

    Abstract: Reprinted with permission ... ...

    Abstract (Reprinted with permission from
    Language English
    Publishing date 2019-04-10
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 1541-4094
    ISSN 1541-4094
    DOI 10.1176/appi.focus.17206
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book: Improving compliance with alcoholism treatment

    Carroll, Kathleen M.

    (Project MATCH monograph series ; 6 ; NIH publication ; 97-4143)

    1997  

    Institution National Institute on Alcohol Abuse and Alcoholism
    Author's details National Institute on Alcohol Abuse and Alcoholism. Ed. by Kathleen M. Carroll
    Series title Project MATCH monograph series ; 6
    NIH publication ; 97-4143
    Collection
    Keywords Alcoholism / therapy ; Patient Compliance ; Physician-Patient Relations
    Language English
    Size VII, 104 S.
    Publisher U.S. Dep. of Health and Human Services
    Publishing place Bethesda, Md
    Publishing country United States
    Document type Book
    HBZ-ID HT014423038
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2005 A 2665 order for loan Magazin

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  7. Article ; Online: Real-time evaluation and adaptation to facilitate rapid recruitment in a large, prospective cohort study.

    Honushefsky, Ashley / Wagner, Eric S / Sheridan, Kathleen / Spickard, Kathleen M / LeMasters, William R / Walter, Carroll N / Beaver, Taryn / Lennon, Anne Marie / Papadopoulos, Nickolas / Rahm, Alanna Kulchak / Buchanan, Adam H

    BMC health services research

    2024  Volume 24, Issue 1, Page(s) 336

    Abstract: Background: Recruiting large cohorts efficiently can speed the translation of findings into care across a range of scientific disciplines and medical specialties. Recruitment can be hampered by factors such as financial barriers, logistical concerns, ... ...

    Abstract Background: Recruiting large cohorts efficiently can speed the translation of findings into care across a range of scientific disciplines and medical specialties. Recruitment can be hampered by factors such as financial barriers, logistical concerns, and lack of resources for patients and clinicians. These and other challenges can lead to underrepresentation in groups such as rural residents and racial and ethnic minorities. Here we discuss the implementation of various recruitment strategies for enrolling participants into a large, prospective cohort study, assessing the need for adaptations and making them in real-time, while maintaining high adherence to the protocol and high participant satisfaction.
    Methods: While conducting a large, prospective trial of a multi-cancer early detection blood test at Geisinger, an integrated health system in central Pennsylvania, we monitored recruitment progress, adherence to the protocol, and participants' satisfaction. Tracking mechanisms such as paper records, electronic health records, research databases, dashboards, and electronic files were utilized to measure each outcome. We then reviewed study procedures and timelines to list the implementation strategies that were used to address barriers to recruitment, protocol adherence and participant satisfaction.
    Results: Adaptations to methods that contributed to achieving the enrollment goal included offering multiple recruitment options, adopting group consenting, improving visit convenience, increasing the use of electronic capture and the tracking of data and source documents, staffing optimization via leveraging resources external to the study team when appropriate, and integrating the disclosure of study results into routine clinical care without adding unfunded work for clinicians. We maintained high protocol adherence and positive participant experience as exhibited by a very low rate of protocol deviations and participant complaints.
    Conclusion: Recruiting rapidly for large studies - and thereby facilitating clinical translation - requires a nimble, creative approach that marshals available resources and changes course according to data. Planning a rigorous assessment of a study's implementation outcomes prior to study recruitment can further ground study adaptations and facilitate translation into practice. This can be accomplished by proactively and continuously assessing and revising implementation strategies.
    MeSH term(s) Humans ; Pennsylvania ; Prospective Studies ; Neoplasms ; Early Detection of Cancer ; Hematologic Tests
    Language English
    Publishing date 2024-03-13
    Publishing country England
    Document type Clinical Trial ; Journal Article
    ZDB-ID 2050434-2
    ISSN 1472-6963 ; 1472-6963
    ISSN (online) 1472-6963
    ISSN 1472-6963
    DOI 10.1186/s12913-024-10750-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Computerized Cognitive-Behavioral Therapy.

    Carroll, Kathleen M

    Alcohol research : current reviews

    2014  Volume 36, Issue 1, Page(s) 127–130

    MeSH term(s) Alcohol-Related Disorders/therapy ; Cognitive Therapy/instrumentation ; Cognitive Therapy/methods ; Humans ; User-Computer Interface
    Language English
    Publishing date 2014
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2168-3492
    ISSN 2168-3492
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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  9. Article ; Online: Galantamine to reduce relapse after agonist taper for individuals with opioid use disorder.

    Sofuoglu, Mehmet / Shi, Julia M / Carroll, Kathleen M

    Drug and alcohol dependence

    2019  Volume 203, Page(s) 98

    Language English
    Publishing date 2019-08-03
    Publishing country Ireland
    Document type Letter
    ZDB-ID 519918-9
    ISSN 1879-0046 ; 0376-8716
    ISSN (online) 1879-0046
    ISSN 0376-8716
    DOI 10.1016/j.drugalcdep.2019.05.013
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  10. Article ; Online: Lost in translation? Moving contingency management and cognitive behavioral therapy into clinical practice.

    Carroll, Kathleen M

    Annals of the New York Academy of Sciences

    2014  Volume 1327, Page(s) 94–111

    Abstract: In the treatment of addictions, the gap between the availability of evidence-based therapies and their limited implementation in practice has not yet been bridged. Two empirically validated behavioral therapies, contingency management (CM) and cognitive ... ...

    Abstract In the treatment of addictions, the gap between the availability of evidence-based therapies and their limited implementation in practice has not yet been bridged. Two empirically validated behavioral therapies, contingency management (CM) and cognitive behavioral therapy (CBT), exemplify this challenge. Both have a relatively strong level of empirical support but each has weak and uneven adoption in clinical practice. This review highlights examples of how barriers to their implementation in practice have been addressed systematically, using the Stage Model of Behavioral Therapies Development as an organizing framework. For CM, barriers such as cost and ideology have been addressed through the development of lower-cost and other adaptations to make it more community friendly. For CBT, barriers such as relative complexity, lack of trained providers, and need for supervision have been addressed via conversion to standardized computer-assisted versions that can serve as clinician extenders. Although these and other modifications have rendered both interventions more disseminable, diffusion of innovation remains a complex, often unpredictable process. The existing specialty addiction-treatment system may require significant reforms to fully implement CBT and CM, particularly greater focus on definable treatment goals and performance-based outcomes.
    MeSH term(s) Behavior, Addictive/drug therapy ; Behavior, Addictive/psychology ; Behavior, Addictive/therapy ; Cognitive Behavioral Therapy ; Combined Modality Therapy ; Evidence-Based Medicine ; Humans ; Models, Psychological ; National Institute on Drug Abuse (U.S.) ; Practice Guidelines as Topic ; Psychological Theory ; Reinforcement, Social ; Substance-Related Disorders/drug therapy ; Substance-Related Disorders/psychology ; Substance-Related Disorders/therapy ; Translational Research, Biomedical ; United States
    Language English
    Publishing date 2014-09-09
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Review
    ZDB-ID 211003-9
    ISSN 1749-6632 ; 0077-8923
    ISSN (online) 1749-6632
    ISSN 0077-8923
    DOI 10.1111/nyas.12501
    Database MEDical Literature Analysis and Retrieval System OnLINE

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