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  1. Article: East meets West: what opportunities arise in comparing international guidelines for management of cirrhosis?

    Idami, Celyn / Mahmud, Nadim

    Hepatobiliary surgery and nutrition

    2023  Volume 12, Issue 1, Page(s) 121–123

    Language English
    Publishing date 2023-01-11
    Publishing country China (Republic : 1949- )
    Document type Editorial ; Comment
    ZDB-ID 2812398-0
    ISSN 2304-389X ; 2304-3881
    ISSN (online) 2304-389X
    ISSN 2304-3881
    DOI 10.21037/hbsn-22-602
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Reply.

    Khan, Nabeel / Mahmud, Nadim

    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

    2023  Volume 21, Issue 7, Page(s) 1972–1973

    Language English
    Publishing date 2023-02-16
    Publishing country United States
    Document type Letter
    ZDB-ID 2119789-1
    ISSN 1542-7714 ; 1542-3565
    ISSN (online) 1542-7714
    ISSN 1542-3565
    DOI 10.1016/j.cgh.2023.02.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5836: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Book ; Thesis: Analyse der Stabilität und dosisabhängigen Wirkung von Pals1

    Mahmud, Nadia

    2022  

    Institution Westfälische Wilhelms-Universität Münster
    Author's details vorgelegt von Nadia Mahmud aus Duisburg
    Language German
    Size 106 Blätter, Illustrationen, Diagramme
    Publishing place Münster
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Universität Münster, 2022
    HBZ-ID HT021403232
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2022 E 667 order for loan Magazin

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  4. Article: Statins in Cirrhosis: Hope or Hype?

    Shaffer, Lauren R / Mahmud, Nadim

    Journal of clinical and experimental hepatology

    2023  Volume 13, Issue 6, Page(s) 1032–1046

    Abstract: In recent years, studies have demonstrated the benefits of statins in a range of chronic diseases separate from cardiovascular outcomes. Early studies in the context of chronic liver disease have suggested favorable effects of statins leading to slowed ... ...

    Abstract In recent years, studies have demonstrated the benefits of statins in a range of chronic diseases separate from cardiovascular outcomes. Early studies in the context of chronic liver disease have suggested favorable effects of statins leading to slowed fibrosis progression, reduced portal pressures, decreased rates of hepatic decompensation, and improved survival. This has increased interest in the potential role that statins may have in the management of chronic liver disease and cirrhosis, though many questions remain unanswered, including concerns regarding the safety of higher dose statins in patients with advanced decompensated cirrhosis. In this review, we provide an update on the current literature addressing the use of statins in patients with cirrhosis and highlight areas in which additional studies are needed.
    Language English
    Publishing date 2023-05-12
    Publishing country India
    Document type Journal Article ; Review
    ISSN 0973-6883
    ISSN 0973-6883
    DOI 10.1016/j.jceh.2023.05.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Selection for Liver Transplantation: Indications and Evaluation.

    Mahmud, Nadim

    Current hepatology reports

    2020  Volume 19, Issue 3, Page(s) 203–212

    Abstract: Purpose of review: Liver transplantation is an important therapeutic option for patients with life-limiting liver disease, which may present in the form of acute liver failure, end-stage chronic liver disease, primary hepatic cancers, or inborn ... ...

    Abstract Purpose of review: Liver transplantation is an important therapeutic option for patients with life-limiting liver disease, which may present in the form of acute liver failure, end-stage chronic liver disease, primary hepatic cancers, or inborn metabolic disorders. While significant strides have been made with respect to liver transplantation outcomes, the practice is constrained by an organ supply/demand mismatch. The purpose of this review, therefore, is to review the general indications and contraindication to liver transplantation, and to provide an overview of the transplant evaluation process. These considerations ultimately shape the specific criteria for patient selection, which will continue to evolve as means are developed to expand the donor pool, improve surgical techniques, broaden indications for safe transplant, and extend the lifetime of a graft.
    Recent findings: Selected patients with unresectable hilar cholangiocarcinoma may be candidates for liver transplantation. Patients over 65 years may be transplant candidates if they possess a favorable comorbidity profile. Patients at body mass index extremes (≥ 40 or < 18.5) have increased post-transplant mortality and require nutritional evaluation.
    Summary: Liver transplantation may be life saving for patients with acute liver failure or end-stage liver disease. It is therefore critical for healthcare providers caring for patients with liver disease to be familiar with the general indications for transplantation and to know when it is appropriate or inappropriate to refer for transplant evaluation.
    Keywords covid19
    Language English
    Publishing date 2020-06-19
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2813071-6
    ISSN 2195-9595 ; 2195-9595 ; 1540-3416
    ISSN (online) 2195-9595
    ISSN 2195-9595 ; 1540-3416
    DOI 10.1007/s11901-020-00527-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: The Impact of Weight Loss Programs on BMI Trajectory in Patients with Metabolic Dysfunction-Associated Steatotic Liver Disease: A Veterans Health Administration Study.

    Tang, Helen / Kaplan, David E / Mahmud, Nadim

    The American journal of gastroenterology

    2024  

    Abstract: Background: Weight loss is the mainstay of management for patients with metabolic dysfunction-associated steatotic liver disease. We studied the impact of referral to MOVE!, a nationally-implemented behavioral weight loss program, on weight in MASLD ... ...

    Abstract Background: Weight loss is the mainstay of management for patients with metabolic dysfunction-associated steatotic liver disease. We studied the impact of referral to MOVE!, a nationally-implemented behavioral weight loss program, on weight in MASLD patients.
    Methods: This retrospective cohort study included 102,294 MASLD patients from 125 Veterans Health Administration centers from 2008-2022.
    Results: Most patients lost no significant weight or gained weight. Increased engagement with MOVE! was associated with greater hazard of significant weight loss compared to no engagement.
    Conclusion: A minority of patients experienced significant weight loss through 5 years using lifestyle interventions alone.
    Language English
    Publishing date 2024-03-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 390122-1
    ISSN 1572-0241 ; 0002-9270
    ISSN (online) 1572-0241
    ISSN 0002-9270
    DOI 10.14309/ajg.0000000000002785
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ui V Zs.36: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Assessing the risk of surgery in patients with cirrhosis.

    Kaltenbach, Melissa G / Mahmud, Nadim

    Hepatology communications

    2023  Volume 7, Issue 4

    Abstract: Patients with cirrhosis have an increased perioperative risk relative to patients without cirrhosis. This is related to numerous cirrhosis-specific factors, including severity of liver disease, impaired synthetic function, sarcopenia and malnutrition, ... ...

    Abstract Patients with cirrhosis have an increased perioperative risk relative to patients without cirrhosis. This is related to numerous cirrhosis-specific factors, including severity of liver disease, impaired synthetic function, sarcopenia and malnutrition, and portal hypertension, among others. Nonhepatic comorbidities and surgery-related factors further modify the surgical risk, adding to the complexity of the preoperative assessment. In this review, we discuss the pathophysiological contributors to surgical risk in cirrhosis, key elements of the preoperative risk assessment, and application of risk prediction tools including the Child-Turcotte-Pugh score, Model for End-Stage Liver Disease-Sodium, Mayo Risk Score, and the VOCAL-Penn Score. We also detail the limitations of current approaches to risk assessment and highlight areas for future research.
    MeSH term(s) Humans ; End Stage Liver Disease ; Severity of Illness Index ; Liver Cirrhosis/complications ; Liver Cirrhosis/surgery ; Risk Factors ; Risk Assessment
    Language English
    Publishing date 2023-03-30
    Publishing country United States
    Document type Review ; Journal Article ; Research Support, N.I.H., Extramural
    ISSN 2471-254X
    ISSN (online) 2471-254X
    DOI 10.1097/HC9.0000000000000086
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Con: Patients With Acute-on-Chronic Liver Failure Should Not Receive Priority on the Waiting List.

    Mahmud, Nadim / Reddy, K Rajender

    Clinical liver disease

    2022  Volume 19, Issue 5, Page(s) 207–212

    Abstract: Content available: Audio Recording. ...

    Abstract Content available: Audio Recording.
    Language English
    Publishing date 2022-05-20
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2657644-2
    ISSN 2046-2484
    ISSN 2046-2484
    DOI 10.1002/cld.1193
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Surgical risk stratification in patients with cirrhosis.

    Ostojic, Ana / Mahmud, Nadim / Reddy, K Rajender

    Hepatology international

    2024  

    Abstract: Individuals with cirrhosis experience higher morbidity and mortality rates than the general population, irrespective of the type or scope of surgery. This increased risk is attributed to adverse effects of liver disease, encompassing coagulation ... ...

    Abstract Individuals with cirrhosis experience higher morbidity and mortality rates than the general population, irrespective of the type or scope of surgery. This increased risk is attributed to adverse effects of liver disease, encompassing coagulation dysfunction, altered metabolism of anesthesia and sedatives, immunologic dysfunction, hemorrhage related to varices, malnutrition and frailty, impaired wound healing, as well as diminished portal blood flow, overall hepatic circulation, and hepatic oxygen supply during surgical procedures. Therefore, a frequent clinical dilemma is whether surgical interventions should be pursued in patients with cirrhosis. Several risk scores are widely used to aid in the decision-making process, each with specific advantages and limitations. This review aims to discuss the preoperative risk factors in patients with cirrhosis, describe and compare surgical risk assessment models used in everyday practice, provide insights into the surgical risk according to the type of surgery and present recommendations for optimizing those with cirrhosis for surgical procedures. As the primary focus is on currently available risk models, the review describes the predictive value of each model, highlighting its specific advantages and limitations. Furthermore, for models that do not account for the type of surgical procedure to be performed, the review suggests incorporating both patient-related and surgery-related risks into the decision-making process. Finally, we provide an algorithm for the preoperative assessment of patients with cirrhosis before elective surgery as well as guidance perioperative management.
    Language English
    Publishing date 2024-03-12
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2270316-0
    ISSN 1936-0541 ; 1936-0533
    ISSN (online) 1936-0541
    ISSN 1936-0533
    DOI 10.1007/s12072-024-10644-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Reply.

    Mahmud, Nadim / Serper, Marina / Kaplan, David E

    Gastroenterology

    2022  Volume 163, Issue 6, Page(s) 1718–1719

    Language English
    Publishing date 2022-08-27
    Publishing country United States
    Document type Letter
    ZDB-ID 80112-4
    ISSN 1528-0012 ; 0016-5085
    ISSN (online) 1528-0012
    ISSN 0016-5085
    DOI 10.1053/j.gastro.2022.08.039
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ui V Zs.44: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
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    Zs.MO 572: Show issues

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