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Article ; Online: Rapid characterization of non-volatile phenolic compounds reveals the reliable chemical markers for authentication of traditional Chinese medicine Xiang-ru among confusing Elsholtzia species.

Zeng, Zhen / Zhang, Chen / Hu, Jiadong / Wang, Feiyan / Wu, Ziding / Wang, Jing / Zhang, Jun / Yang, Shuda / Chen, Junfeng / Li, Mingming / Tong, Qi / Qiu, Shi / Chen, Wansheng

Chinese journal of natural medicines

2024 Volume 22, Issue 4, Page(s) 375–384

Abstract: ... utilized in traditional Chinese medicine (TCM), known collectively as Xiang-ru. However, due to clinical ... as reliable chemical markers for distinguishing Xiang-ru from closely related Elsholtzia species ...

Abstract	The aerial parts of Mosla chinensis Maxim. and Mosla chinensis cv. 'Jiangxiangru' (MCJ) are widely utilized in traditional Chinese medicine (TCM), known collectively as Xiang-ru. However, due to clinical effectiveness concerns and frequent misidentification, the original plants have increasingly been substituted by various species within the genera Elsholtzia and Mosla. The challenge in distinguishing between these genera arises from their similar morphological and metabolic profiles. To address this issue, our study introduced a rapid method for metabolic characterization, employing high-resolution mass spectrometry-based metabolomics. Through detailed biosynthetic and chemometric analyses, we pinpointed five phenolic compounds-salviaflaside, cynaroside, scutellarein-7-O-D-glucoside, rutin, and vicenin-2-among 203 identified compounds, as reliable chemical markers for distinguishing Xiang-ru from closely related Elsholtzia species. This methodology holds promise for broad application in the analysis of plant aerial parts, especially in verifying the authenticity of aromatic traditional medicinal plants. Our findings underscore the importance of non-volatile compounds as dependable chemical markers in the authentication process of aromatic traditional medicinal plants.
MeSH term(s)	Phenols/analysis ; Phenols/chemistry ; Drugs, Chinese Herbal/chemistry ; Drugs, Chinese Herbal/analysis ; Lamiaceae/chemistry ; Lamiaceae/classification ; Medicine, Chinese Traditional ; Metabolomics/methods ; Mass Spectrometry/methods ; Plant Components, Aerial/chemistry
Chemical Substances	Phenols ; Drugs, Chinese Herbal
Language	English
Publishing date	2024-01-11
Publishing country	China
Document type	Journal Article ; Evaluation Study
ZDB-ID	2192577-X
ISSN	1875-5364 ; 2095-6975 ; 1672-3651
ISSN (online)	1875-5364
ISSN	2095-6975 ; 1672-3651
DOI	10.1016/S1875-5364(24)60614-X
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Big data analysis of water quality monitoring results from the Xiang River and an impact analysis of pollution management policies.

Zeng, Yangyan / Zhou, Yidong / Cao, Wenzhi / Hu, Dongbin / Luo, Yueping / Pan, Haiting

Mathematical biosciences and engineering : MBE

2023 Volume 20, Issue 5, Page(s) 9443–9469

Abstract: Water pollution prevention and control of the Xiang River has become an issue of great concern ... local governmental policies on water pollution prevention and control for the Xiang River, this study performs a big ... of the Xiang River, Hunan Province, China from 2005 to 2016. This study uses an evidential reasoning-based ...

Abstract	Water pollution prevention and control of the Xiang River has become an issue of great concern to China's central and local governments. To further analyze the effects of central and local governmental policies on water pollution prevention and control for the Xiang River, this study performs a big data analysis of 16 water quality parameters from 42 sections of the mainstream and major tributaries of the Xiang River, Hunan Province, China from 2005 to 2016. This study uses an evidential reasoning-based integrated assessment of water quality and principal component analysis, identifying the spatiotemporal changes in the primary pollutants of the Xiang River and exploring the correlations between potentially relevant factors. The analysis showed that a series of environmental protection policies implemented by Hunan Province since 2008 have had a significant and targeted impact on annual water quality pollutants in the mainstream and tributaries. In addition, regional industrial structures and management policies also have had a significant impact on regional water quality. The results showed that, when examining the changes in water quality and the effects of pollution control policies, a big data analysis of water quality monitoring results can accurately reveal the detailed relationships between management policies and water quality changes in the Xiang River. Compared with policy impact evaluation methods primarily based on econometric models, such a big data analysis has its own advantages and disadvantages, effectively complementing the traditional methods of policy impact evaluations. Policy impact evaluations based on big data analysis can further improve the level of refined management by governments and provide a more specific and targeted reference for improving water pollution management policies for the Xiang River.
Language	English
Publishing date	2023-05-10
Publishing country	United States
Document type	Journal Article
ZDB-ID	2265126-3
ISSN	1551-0018 ; 1551-0018
ISSN (online)	1551-0018
ISSN	1551-0018
DOI	10.3934/mbe.2023415
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: A study related to the treatment of gastric cancer with Xiang-Sha-Liu-Jun-Zi-Tang based on network analysis.

Jiang, Ke / Liu, Heli / Ge, Jie / Yang, Bo / Wang, Yu / Wang, Wenbo / Wen, Yuqi / Zeng, Siqing / Chen, Quan / Huang, Jun / Xiong, Xingui

Heliyon

2023 Volume 9, Issue 9, Page(s) e19546

Abstract: Purpose: Xiang-Sha-Liu-Jun-Zi-Tang(XSLJZT) is a common formula for the treatment of Gastric Cancer ...

Abstract	Purpose: Xiang-Sha-Liu-Jun-Zi-Tang(XSLJZT) is a common formula for the treatment of Gastric Cancer(GC) and is widely used in clinical practice, however, there is a lack of investigation into its mechanism. Methods: We collected and organized drug and disease targets, constructed the "XSLJZT-Active Ingredient-Target" visualization network, and performed GO and KEGG functional enrichment analysis of crossover genes, followed by molecular docking of active ingredients and core targets. The best docked monomers were combined with weighted gene co-expression network analysis(WGCNA) and macroscopically analyzed by GO and KEGG enrichment techniques. The results of cluster gene difference analysis, ROC evaluation, and CIBERSORT immune infiltration analysis were evaluated and finally supported by cellular experiments. Results: The main components of XSLJZT are quercetin, stigmasterol, and naringenin, effectively treat GC by targeting STAT3, TP53 and MAPK3, which are involved in IL-17, TNF and HIF-1 signaling pathways. The results of molecular docking showed that quercetin bound better to the core targets. We performed an in-depth analysis of this monomer and found that quercetin acts on the core targets of TP53, MMP9, TIMP1 and MYC, and is involved in two key signaling pathways, TNF and IL-17, thus effectively treating GC. The experimental results are consistent with our analysis that quercetin inhibits the proliferation of GC cells and promotes apoptosis, and TP53, MYC and TIMP1 are the quercetin targets for the treatment of GC. Conclusion: The present study tentatively suggests that quercetin, the main active ingredient in XSLJZT, can exert a therapeutic effect on GC by targeting TIMP1.
Language	English
Publishing date	2023-08-28
Publishing country	England
Document type	Journal Article
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2023.e19546
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Carya luana C.‐Y. Deng et X.‐G. Xiang, sp. nov. (Juglandaceae), a new species from Guizhou, China, identified based on whole plastome phylogeny and morphometrics

Xiang, Xiao‐Guo / Deng, Chao‐Yi / Yan, Hua / Liu, Yu‐Juan / Liu, Zeng‐Cai / Cheng, Kun / Ban, Qi‐Ming / Lang, Yuan‐Xing

Nordic Journal of Botany. 2023 May, v. 2023, no. 5 p.e03867-

2023

Abstract: Carya luana sp. nov., a new species of Juglandaceae from Guizhou, China, is described and illustrated. The new species is easily distinguished from other Carya species by having lanceolate leaflets and obovate fruits with a 4–6 mm thick husk, but is ... ...

Abstract	Carya luana sp. nov., a new species of Juglandaceae from Guizhou, China, is described and illustrated. The new species is easily distinguished from other Carya species by having lanceolate leaflets and obovate fruits with a 4–6 mm thick husk, but is otherwise morphologically close to C. tonkinensis and C. kweichowensis. Based on phylogenetic reconstruction of whole plastomes, C. luana is the sister of C. tonkinensis, while formed a clade with C. tonkinensis and C. hunanensis on ITS. A morphometric analysis demonstrate that C. luana, C. tonkinensis and C. kweichowensis are morphologically distinct. The conservation status of C. luana is assessed as Endangered (EN) according to the IUCN Red List Categories and Criteria. A new identification key to all Asian Carya species is provided.
Keywords	Carya ; botany ; conservation status ; hulls ; morphometry ; new species ; phylogeny ; taxonomic keys ; China
Language	English
Dates of publication	2023-05
Publishing place	Blackwell Publishing Ltd
Document type	Article ; Online
Note	JOURNAL ARTICLE
ZDB-ID	2406507-9
ISSN	1756-1051 ; 0107-055X
ISSN (online)	1756-1051
ISSN	0107-055X
DOI	10.1111/njb.03867
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: A study related to the treatment of gastric cancer with Xiang-Sha-Liu-Jun-Zi-Tang based on network analysis

Ke Jiang / Heli Liu / Jie Ge / Bo Yang / Yu Wang / Wenbo Wang / Yuqi Wen / Siqing Zeng / Quan Chen / Jun Huang / Xingui Xiong

Heliyon, Vol 9, Iss 9, Pp e19546- (2023)

2023

Abstract: Purpose: Xiang-Sha-Liu-Jun-Zi-Tang(XSLJZT) is a common formula for the treatment of Gastric Cancer ...

Abstract	Purpose: Xiang-Sha-Liu-Jun-Zi-Tang(XSLJZT) is a common formula for the treatment of Gastric Cancer(GC) and is widely used in clinical practice, however, there is a lack of investigation into its mechanism. Methods: We collected and organized drug and disease targets, constructed the “XSLJZT-Active Ingredient-Target” visualization network, and performed GO and KEGG functional enrichment analysis of crossover genes, followed by molecular docking of active ingredients and core targets. The best docked monomers were combined with weighted gene co-expression network analysis(WGCNA) and macroscopically analyzed by GO and KEGG enrichment techniques. The results of cluster gene difference analysis, ROC evaluation, and CIBERSORT immune infiltration analysis were evaluated and finally supported by cellular experiments. Results: The main components of XSLJZT are quercetin, stigmasterol, and naringenin, effectively treat GC by targeting STAT3, TP53 and MAPK3, which are involved in IL-17, TNF and HIF-1 signaling pathways. The results of molecular docking showed that quercetin bound better to the core targets. We performed an in-depth analysis of this monomer and found that quercetin acts on the core targets of TP53, MMP9, TIMP1 and MYC, and is involved in two key signaling pathways, TNF and IL-17, thus effectively treating GC. The experimental results are consistent with our analysis that quercetin inhibits the proliferation of GC cells and promotes apoptosis, and TP53, MYC and TIMP1 are the quercetin targets for the treatment of GC. Conclusion: The present study tentatively suggests that quercetin, the main active ingredient in XSLJZT, can exert a therapeutic effect on GC by targeting TIMP1.
Keywords	XSLJZT ; GC ; Network Pharmacology ; Molecular Docking ; WGCNA ; Mechanism of action ; Science (General) ; Q1-390 ; Social sciences (General) ; H1-99
Subject code	004
Language	English
Publishing date	2023-09-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Impact of anthropogenic activities on changes of ichthyofauna in the middle and lower Xiang River

Zeng, Cong / Wen, Yao / Liu, Xinhua / Yu, Jianbo / Jin, Binsong / Li, Deliang

Shanghai Ocean University. Aquaculture and fisheries. 2021 June 24,

2021

Abstract: ... composition by environmental DNA metabarcoding in the urban and suburban sites along Xiang River in central ...

Abstract	With the population increasing, fish communities, as important components in the river system, were inescapably impacted by human activities. To investigate these impacts, we characterized the fish community's composition by environmental DNA metabarcoding in the urban and suburban sites along Xiang River in central China. The results showed that 32 species were identified, and most species were from Cypriniform. The analysis indicated no significant differences in fish communities among the three urban areas. However, significant differences were observed between the bank solidified and non-solidified areas, which indicated that the channelization significantly influenced the biodiversity and abundances. An alien species, Clarias gariepinus, was discovered in all examined sites, and it was negatively associated with ten native species. Furthermore, human populations and acidification were also negatively related to diversity. Our findings clearly showed that the consequences of anthropogenic activities shaped ichthyofauna and caused biodiversity loss in the urban river.
Keywords	Clarias gariepinus ; DNA barcoding ; acidification ; aquaculture ; biodiversity ; channelization ; environmental DNA ; fish ; fish communities ; humans ; indigenous species ; introduced species ; rivers ; China
Language	English
Dates of publication	2021-0624
Publishing place	Elsevier B.V.
Document type	Article
Note	Pre-press version
ISSN	2468-550X
DOI	10.1016/j.aaf.2021.06.007
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Analysis of the Rongshui Xiang duck (Anseriformes, Anatidae, Anas) mitochondrial DNA.

Zhang, Yanfang / Xie, Zhixun / Xie, Liji / Deng, Xianwen / Xie, Zhiqin / Huang, Li / Huang, Jiaoling / Zeng, Tingting

Mitochondrial DNA. Part A, DNA mapping, sequencing, and analysis

2016 Volume 27, Issue 3, Page(s) 1867–1868

Abstract: The complete mitochondrial genome sequence of the Rongshui Xiang duck was measured by PCR-based ... methods. Our research findings reveal that the entire mitochondrial genome of the Rongshui Xiang duck is ... similar to the majority of avian species. The complete mitochondrial genome of the Rongshui Xiang duck ...

Abstract	The complete mitochondrial genome sequence of the Rongshui Xiang duck was measured by PCR-based methods. Our research findings reveal that the entire mitochondrial genome of the Rongshui Xiang duck is a circular molecule consisting of 16,605 bp (GenBank accession number: KJ833587). The contents of A, T, C, and G in the mitochondrial genome were found to be 29.20%, 22.20%, 32.82% and 15.79%, respectively, similar to the majority of avian species. The complete mitochondrial genome of the Rongshui Xiang duck contains 13 protein-coding genes, 2 rRNA genes, 22 tRNA genes, and 1 control region. The characteristics of the mitochondrial genome were analyzed in detail. Our complete mitochondrial genome sequence should provide essential information for understanding phylogenetic relationships among duck mitochondrial genomes.
Language	English
Publishing date	2016-05
Publishing country	England
Document type	Journal Article
ISSN	2470-1408
ISSN (online)	2470-1408
DOI	10.3109/19401736.2014.971263
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Book: Xin er er ba shi xiang

Zeng, Jianmin

zui xin chu tu shi jian xiao shuo . shi . bao dao . ping lun

(Guang fu hou wu nian shi cong shu ; 1 ; 光復後五年史叢書 ; 1)

2003

Author's details	zeng jian min yan bian
Series title	Guang fu hou wu nian shi cong shu ; 1 光復後五年史叢書 ; 1
Language	Chinese
Size	408 S
Edition	Chu ban
Publisher	Tai wan she hui ke xue chu ban
Publishing place	Tai bei
Document type	Book
ISBN	957285500X ; 9789572855003
Database	Former special subject collection: coastal and deep sea fishing

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Book ; Online: Entity Alignment

Zhao, Xiang / Zeng, Weixin / Tang, Jiuyang

Concepts, Recent Advances and Novel Approaches

(Big Data Management)

2023

Author's details	by Xiang Zhao, Weixin Zeng, Jiuyang Tang
Series title	Big Data Management
Keywords	Expert systems (Computer science) ; Data mining ; Artificial intelligence/Data processing
Language	English
Size	1 Online-Ressource (XI, 247 p. 1 illus)
Edition	1st ed. 2023
Publisher	Springer Nature Singapore ; Imprint: Springer
Publishing place	Singapore
Document type	Book ; Online
HBZ-ID	HT030389724
ISBN	978-981-99-4250-3 ; 9789819942497 ; 9789819942510 ; 9789819942527 ; 981-99-4250-0 ; 9819942497 ; 9819942519 ; 9819942527
DOI	10.1007/978-981-99-4250-3
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Book ; Online: Entity Alignment

Zhao, Xiang / Zeng, Weixin / Tang, Jiuyang

Concepts, Recent Advances and Novel Approaches

(Big Data Management)

2023

Series title	Big Data Management
Keywords	Expert systems / knowledge-based systems ; Data mining ; Algorithms & data structures ; Artificial intelligence ; Knowledge Graph ; Entity Alignment ; Knowledge Graph Alignment ; Knowledge Graph Matching ; Entity Matching ; Knowledge Fusion ; Data Integration ; Knowledge Graph Representation Learning ; Multi-Modal Knowledge Graph
Language	English
Size	1 electronic resource (247 pages)
Publisher	Springer Nature
Publishing place	Singapore
Document type	Book ; Online
Note	English
HBZ-ID	HT030613304
ISBN	9789819942497 ; 9819942497
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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