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  1. Article ; Online: P

    Murphy, Morgan B / Huang, Abel S / Schick, Suzaynn F

    Environmental health perspectives

    2021  Volume 129, Issue 6, Page(s) 67701

    MeSH term(s) Air Pollutants/analysis ; Cannabis ; Environmental Monitoring ; Particulate Matter/analysis
    Chemical Substances Air Pollutants ; Particulate Matter
    Language English
    Publishing date 2021-06-16
    Publishing country United States
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 195189-0
    ISSN 1552-9924 ; 0091-6765 ; 1078-0475
    ISSN (online) 1552-9924
    ISSN 0091-6765 ; 1078-0475
    DOI 10.1289/EHP8689
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  2. Article ; Online: Giant tidal tails of helium escaping the hot Jupiter HAT-P-32 b.

    Zhang, Zhoujian / Morley, Caroline V / Gully-Santiago, Michael / MacLeod, Morgan / Oklopčić, Antonija / Luna, Jessica / Tran, Quang H / Ninan, Joe P / Mahadevan, Suvrath / Krolikowski, Daniel M / Cochran, William D / Bowler, Brendan P / Endl, Michael / Stefánsson, Gudmundur / Tofflemire, Benjamin M / Vanderburg, Andrew / Zeimann, Gregory R

    Science advances

    2023  Volume 9, Issue 23, Page(s) eadf8736

    Abstract: ... We monitored the hot Jupiter HAT-P-32 b using high-resolution spectroscopy from the Hobby-Eberly Telescope ... covering the planet's full orbit. We detected helium escaping HAT-P-32 b at a 14σ significance ...

    Abstract Capturing planets in the act of losing their atmospheres provides rare opportunities to probe their evolution history. This analysis has been enabled by observations of the helium triplet at 10,833 angstrom, but past studies have focused on the narrow time window right around the planet's optical transit. We monitored the hot Jupiter HAT-P-32 b using high-resolution spectroscopy from the Hobby-Eberly Telescope covering the planet's full orbit. We detected helium escaping HAT-P-32 b at a 14σ significance,with extended leading and trailing tails spanning a projected length over 53 times the planet's radius. These tails are among the largest known structures associated with an exoplanet. We interpret our observations using three-dimensional hydrodynamic simulations, which predict Roche Lobe overflow with extended tails along the planet's orbital path.
    Language English
    Publishing date 2023-06-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2810933-8
    ISSN 2375-2548 ; 2375-2548
    ISSN (online) 2375-2548
    ISSN 2375-2548
    DOI 10.1126/sciadv.adf8736
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  3. Article ; Online: Premature Complexes and Blocked P Wave.

    Morgan, Ethan / Anderson, John / Noheria, Amit

    Circulation

    2022  Volume 145, Issue 24, Page(s) 1803–1805

    MeSH term(s) Atrial Premature Complexes ; Electrocardiography ; Humans ; Ventricular Premature Complexes/diagnosis
    Language English
    Publishing date 2022-06-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80099-5
    ISSN 1524-4539 ; 0009-7322 ; 0069-4193 ; 0065-8499
    ISSN (online) 1524-4539
    ISSN 0009-7322 ; 0069-4193 ; 0065-8499
    DOI 10.1161/CIRCULATIONAHA.122.060345
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  4. Article ; Online: Enantioselective Copper-Catalyzed Alkynylation of Quinolones Using Chiral P,N Ligands.

    Morgan, Dáiríne M / Reid, Cian M / Guiry, Patrick J

    The Journal of organic chemistry

    2023  Volume 89, Issue 3, Page(s) 1993–2000

    Abstract: Herein we report a catalytic enantioselective alkynylation of quinolones. In this reaction, quinolones are silylated to form a quinolinium ion which then undergoes an enantioselective attack by a copper acetylide, templated by ( ...

    Abstract Herein we report a catalytic enantioselective alkynylation of quinolones. In this reaction, quinolones are silylated to form a quinolinium ion which then undergoes an enantioselective attack by a copper acetylide, templated by (
    Language English
    Publishing date 2023-11-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 123490-0
    ISSN 1520-6904 ; 0022-3263
    ISSN (online) 1520-6904
    ISSN 0022-3263
    DOI 10.1021/acs.joc.3c01944
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  5. Article ; Online: Driving Recursive Dehydration by P

    Lecomte, Morgan / Lipshultz, Jeffrey M / Kim-Lee, Shin-Ho / Li, Gen / Radosevich, Alexander T

    Journal of the American Chemical Society

    2019  Volume 141, Issue 32, Page(s) 12507–12512

    Abstract: ... azaheterocycles via organophosphorus P ...

    Abstract A method for the annulation of amines and carboxylic acids to form pharmaceutically relevant azaheterocycles via organophosphorus P
    MeSH term(s) Amines/chemistry ; Carbon/chemistry ; Carboxylic Acids/chemistry ; Catalysis ; Cyclization ; Heterocyclic Compounds/chemical synthesis ; Nitrogen/chemistry ; Oxidation-Reduction
    Chemical Substances Amines ; Carboxylic Acids ; Heterocyclic Compounds ; Carbon (7440-44-0) ; Nitrogen (N762921K75)
    Language English
    Publishing date 2019-07-30
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 3155-0
    ISSN 1520-5126 ; 0002-7863
    ISSN (online) 1520-5126
    ISSN 0002-7863
    DOI 10.1021/jacs.9b06277
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  6. Article ; Online: Development and Validation of a Validity Scale for Use with the UPPS-P and Short UPPS-P Impulsive Behavior Scales.

    McCredie, Morgan N / Harris, Bethany / Regan, Timothy / Morey, Leslie C / Fields, Sherecce A

    Journal of personality assessment

    2021  Volume 103, Issue 6, Page(s) 752–761

    Abstract: Two of the most widely used self-report measures of impulsivity are the UPPS-P Impulsive Behavior ... Scale and its shortened version, the SUPPS-P, which currently are limited by their inability to detect ... for use with the UPPS-P and SUPPS-P in order to accurately screen for data quality and better detect ...

    Abstract Two of the most widely used self-report measures of impulsivity are the UPPS-P Impulsive Behavior Scale and its shortened version, the SUPPS-P, which currently are limited by their inability to detect careless and/or random responding. The present study develops and cross-validates an inconsistency scale for use with the UPPS-P and SUPPS-P in order to accurately screen for data quality and better detect invalid responding. A total of 443 participants were recruited from Amazon's MTurk online data collection service to serve as the derivation sample and 231 undergraduates were recruited to serve as the cross-validation sample. The inconsistency scale demonstrated good classification accuracy in differentiating between genuine and random protocols and moderated the relationships between the UPPS-P/SUPPS-P and a criterion measure of impulsivity, the Barratt Impulsiveness Scale-11 (BIS-11). Thus, the inconsistency scale shows promise as an indicator of variable response inconsistency for use with both the UPPS-P and SUPPS-P in community and undergraduate research samples.
    MeSH term(s) Humans ; Impulsive Behavior ; Self Report ; Students
    Language English
    Publishing date 2021-01-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 121962-5
    ISSN 1532-7752 ; 0022-3891
    ISSN (online) 1532-7752
    ISSN 0022-3891
    DOI 10.1080/00223891.2020.1866588
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  7. Article ; Online: Early clinical experience with the straight design of Venus P-valve™ in dysfunctional right ventricular outflow tracts.

    Morgan, Gareth J / Sivakumar, Kothandam / Promphan, Worakan / Goreczny, Sebastian / Prachasilchai, Pimpak / Qureshi, Shakeel

    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions

    2020  Volume 96, Issue 6, Page(s) E653–E659

    Abstract: ... design of the Venus P-valve™ (Venus MedTech, Hangzhou, China) in dysfunctional right ventricular outflow ... percutaneous valve option for smaller RVOT conduits. The straight Venus P-valve™ may provide an alternative ... clinical and imaging follow-up of the straight Venus P-valve™.: Results: Nine patients (four female ...

    Abstract Objectives: To assess the initial procedural and short to medium-term experience with the straight design of the Venus P-valve™ (Venus MedTech, Hangzhou, China) in dysfunctional right ventricular outflow tracts (RVOT).
    Background: The Melody™ valve (Medtronic, Minneapolis, Minnesota) has been the only percutaneous valve option for smaller RVOT conduits. The straight Venus P-valve™ may provide an alternative to the Melody™ valve.
    Methods: Retrospective data collection of patient characteristics, procedural data, clinical and imaging follow-up of the straight Venus P-valve™.
    Results: Nine patients (four female) with a mean age of 23.1 ± 7.5 years and a mean weight of 72.7 ± 29.4 kg underwent straight Venus P-valve™ implantation between 03/2014 and 06/2016. All patients had right ventricle-to-pulmonary artery conduits which were pre-stented before the valve implantation. All valves were deployed successfully without any significant procedural complications. During the mean follow-up of 24 ± 9.1 months, there were no valve related re-interventions or deterioration in valve performance. There was one case of insignificant, single wire frame fracture and no cases of endocarditis. The cohort demonstrated a reduction in pulmonary regurgitation and tricuspid regurgitation, which was sustained throughout the follow-up. Similarly the gradient across the RVOT tract did not significantly increase.
    Conclusions: Implantation of the straight Venus P-valve™ has provided satisfactory short to mid-term results with high success rates and no complications and may be considered as an alternative option in patients with RVOT dysfunction.
    MeSH term(s) Adolescent ; Adult ; Bioprosthesis ; Cardiac Catheterization/adverse effects ; Cardiac Catheterization/instrumentation ; Cardiac Surgical Procedures/adverse effects ; Compassionate Use Trials ; Female ; Heart Defects, Congenital/surgery ; Heart Valve Prosthesis ; Heart Valve Prosthesis Implantation/adverse effects ; Heart Valve Prosthesis Implantation/instrumentation ; Humans ; Male ; Prosthesis Design ; Pulmonary Valve/diagnostic imaging ; Pulmonary Valve/physiopathology ; Pulmonary Valve/surgery ; Pulmonary Valve Insufficiency/diagnostic imaging ; Pulmonary Valve Insufficiency/physiopathology ; Pulmonary Valve Insufficiency/surgery ; Pulmonary Valve Stenosis/diagnostic imaging ; Pulmonary Valve Stenosis/physiopathology ; Pulmonary Valve Stenosis/surgery ; Retrospective Studies ; Treatment Outcome ; Ventricular Outflow Obstruction/diagnostic imaging ; Ventricular Outflow Obstruction/etiology ; Ventricular Outflow Obstruction/physiopathology ; Ventricular Outflow Obstruction/surgery ; Young Adult
    Language English
    Publishing date 2020-02-25
    Publishing country United States
    Document type Journal Article ; Multicenter Study ; Video-Audio Media
    ZDB-ID 1459995-8
    ISSN 1522-726X ; 1522-1946
    ISSN (online) 1522-726X
    ISSN 1522-1946
    DOI 10.1002/ccd.28819
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    Zs.A 1226: Show issues Location:
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  8. Article ; Online: Reply to Augello, P.A.; Wu, J. Comment on "Rogers et al. The Combined Effects of Cannabis, Methamphetamine, and HIV on Neurocognition.

    Rogers, Jeffrey M / Iudicello, Jennifer E / Marcondes, Maria Cecilia G / Morgan, Erin E / Cherner, Mariana / Ellis, Ronald J / Letendre, Scott L / Heaton, Robert K / Grant, Igor

    Viruses

    2023  Volume 15, Issue 9

    Abstract: We thank Augello and Wu [ ... ]. ...

    Abstract We thank Augello and Wu [...].
    MeSH term(s) Cannabis ; Methamphetamine/pharmacology ; HIV Infections
    Chemical Substances Methamphetamine (44RAL3456C)
    Language English
    Publishing date 2023-09-05
    Publishing country Switzerland
    Document type Letter
    ZDB-ID 2516098-9
    ISSN 1999-4915 ; 1999-4915
    ISSN (online) 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v15091878
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  9. Article ; Online: Magma accumulation beneath Santorini volcano, Greece, from P-wave tomography

    McVey, B. / Hooft, E. / Heath, B. / Toomey, D. / Paulatto, M. / Morgan, J. / Nomikou, P. / Papazachos, C.

    Geology

    2020  

    Abstract: ... dimensional (3-D) velocity models from tomographic inversions of active-source seismic P-wave travel times ...

    Abstract Despite multidisciplinary evidence for crustal magma accumulation below Santorini volcano, Greece, the structure and melt content of the shallow magmatic system remain poorly constrained. We use three-dimensional (3-D) velocity models from tomographic inversions of active-source seismic P-wave travel times to identify a pronounced low-velocity anomaly (–21%) from 2.8 km to 5 km depth localized below the northern caldera basin. This anomaly is consistent with depth estimates of pre-eruptive storage and a recent inflation episode, supporting the interpretation of a shallow magma body that causes seismic attenuation and ray bending. A suite of synthetic tests shows that the geometry is well recovered while a range of melt contents (4%–13% to fully molten) are allowable. A thin mush region (2%–7% to 3%–10% melt) extends from the main magma body toward the northeast, observed as low velocities confined by tectono-magmatic lineaments. This anomaly terminates northwest of Kolumbo; little to no melt underlies the seamount from 3 to 5 km depth. These structural constraints suggest that crustal extension and edifice loads control the geometry of magma accumulation and emphasize that the shallow crust remains conducive to melt storage shortly after a caldera-forming eruption. GeoRef Subject Aegean Islands geophysical methods Santorin Europe Greece Greek Aegean Islands Mediterranean region Cyclades magmas Southern Europe
    Subject code 550
    Language English
    Publishing country de
    Document type Article ; Online
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  10. Article ; Online: Development of duplex TaqMan-based real-time PCR assay for the simultaneous detection of Perkinsus olseni and P. chesapeaki in host Manila clam tissue samples.

    Itoïz, Sarah / Perennou, Morgan / Mouronvalle, Clara / Derelle, Evelyne / Le Goïc, Nelly / Bidault, Adeline / de Montaudouin, Xavier / Arzul, Isabelle / Soudant, Philippe / Chambouvet, Aurélie

    Journal of invertebrate pathology

    2021  Volume 184, Page(s) 107603

    Abstract: ... with P. olseni. Identifying potential cryptic infections affecting Ruditapes philippinarum is essential ... on duplex real-time quantitative PCR for the simultaneous detection of these two parasites, P. olseni and P ...

    Abstract The aetiological agent Perkinsus olseni is globally recognised as a major threat for shellfish production considering its wide geographical distribution across Asia, Europe, Australia and South America. Another species, Perkinsus chesapeaki, which has never been known to be associated with significant mortality events, was recently detected along French coasts infecting clam populations sporadically in association with P. olseni. Identifying potential cryptic infections affecting Ruditapes philippinarum is essential to develop appropriate host resource management strategies. Here, we developed a molecular method based on duplex real-time quantitative PCR for the simultaneous detection of these two parasites, P. olseni and P. chesapeaki, in the different clam tissues: gills, digestive gland, foot, mantle, adductor muscle and the rest of the soft body. We firstly checked the presence of possible PCR inhibitors in host tissue samples. The qPCR reactions were inhibited depending on the nature of the host organ. The mantle and the rest of the soft body have a high inhibitory effect from threshold of host gDNA concentration of 2 ng.µL
    MeSH term(s) Alveolata/genetics ; Alveolata/isolation & purification ; Animals ; Bivalvia/parasitology ; Real-Time Polymerase Chain Reaction/methods ; Species Specificity
    Language English
    Publishing date 2021-05-07
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 390885-9
    ISSN 1096-0805 ; 0022-2011
    ISSN (online) 1096-0805
    ISSN 0022-2011
    DOI 10.1016/j.jip.2021.107603
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