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Article: Spendthrifts and Tightwads in Childhood: Feelings about Spending Predict Children's Financial Decision-Making.

Smith, Craig E / Echelbarger, Margaret / Gelman, Susan A / Rick, Scott I

2017 Volume 31, Issue 3, Page(s) 446–460

Abstract: ... e.g., saving behavior, credit scores). Although children's financial behavior has also received ...

Abstract	Adults differ in the extent to which they find spending money to be distressing; "tightwads" find spending money painful and "spendthrifts" do not find spending painful enough. This affective dimension has been reliably measured in adults, and predicts a variety of important financial behaviors and outcomes (e.g., saving behavior, credit scores). Although children's financial behavior has also received attention, feelings about spending have not been studied in children, as they have in adults. We measured the spendthrift-tightwad (ST-TW) construct in children for the first time, with a sample of 5-to-10-year-old children (
Language	English
Publishing date	2017-12-28
Publishing country	England
Document type	Journal Article
ZDB-ID	1477211-5
ISSN	1099-0771 ; 0894-3257
ISSN (online)	1099-0771
ISSN	0894-3257
DOI	10.1002/bdm.2071
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Article ; Online: State of Knowledge on Molecular Adaptations to Exercise in Humans: Historical Perspectives and Future Directions.

Lavin, Kaleen M / Coen, Paul M / Baptista, Liliana C / Bell, Margaret B / Drummer, Devin / Harper, Sara A / Lixandrão, Manoel E / McAdam, Jeremy S / O'Bryan, Samia M / Ramos, Sofhia / Roberts, Lisa M / Vega, Rick B / Goodpaster, Bret H / Bamman, Marcas M / Buford, Thomas W

Comprehensive Physiology

2022 Volume 12, Issue 2, Page(s) 3193–3279

Abstract: For centuries, regular exercise has been acknowledged as a potent stimulus to promote, maintain, and restore healthy functioning of nearly every physiological system of the human body. With advancing understanding of the complexity of human physiology, ... ...

Abstract	For centuries, regular exercise has been acknowledged as a potent stimulus to promote, maintain, and restore healthy functioning of nearly every physiological system of the human body. With advancing understanding of the complexity of human physiology, continually evolving methodological possibilities, and an increasingly dire public health situation, the study of exercise as a preventative or therapeutic treatment has never been more interdisciplinary, or more impactful. During the early stages of the NIH Common Fund Molecular Transducers of Physical Activity Consortium (MoTrPAC) Initiative, the field is well-positioned to build substantially upon the existing understanding of the mechanisms underlying benefits associated with exercise. Thus, we present a comprehensive body of the knowledge detailing the current literature basis surrounding the molecular adaptations to exercise in humans to provide a view of the state of the field at this critical juncture, as well as a resource for scientists bringing external expertise to the field of exercise physiology. In reviewing current literature related to molecular and cellular processes underlying exercise-induced benefits and adaptations, we also draw attention to existing knowledge gaps warranting continued research effort. © 2021 American Physiological Society. Compr Physiol 12:3193-3279, 2022.
MeSH term(s)	Adaptation, Physiological ; Exercise/physiology ; Humans
Language	English
Publishing date	2022-03-09
Publishing country	United States
Document type	Journal Article ; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ISSN	2040-4603
ISSN (online)	2040-4603
DOI	10.1002/cphy.c200033
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Article ; Online: Fractal solar panels: Optimizing aesthetic and electrical performances.

Roe, Ellis T / Bies, Alexander J / Montgomery, Rick D / Watterson, William J / Parris, Blake / Boydston, Cooper R / Sereno, Margaret E / Taylor, Richard P

PloS one

2020 Volume 15, Issue 3, Page(s) e0229945

Abstract: Solar energy technologies have been plagued by their limited visual appeal. Because the electrical power generated by solar panels increases with their surface area and therefore their occupancy of the observer's visual field, aesthetics will play an ... ...

Abstract	Solar energy technologies have been plagued by their limited visual appeal. Because the electrical power generated by solar panels increases with their surface area and therefore their occupancy of the observer's visual field, aesthetics will play an increasingly critical role in their future success in urban environments. Inspired by previous psychology research highlighting the aesthetic qualities of fractal patterns, we investigated panel designs featuring fractal electrodes. We conducted behavioral studies which compared observers' preferences for fractal and conventional bus-bar electrode patterns, along with computer simulations which compared their electrical performances. This led us to develop a hybrid electrode pattern which best combines the fractal and bus-bar designs. Here we show that the new hybrid electrode matches the electrical performance of bus-bars in terms of light transmission and minimizing electrical power losses, while benefiting from the superior aesthetics of fractal patterns. This innovative integration of psychology and engineering studies provides a framework for developing novel electrode patterns with increased implementation and acceptance.
MeSH term(s)	Adolescent ; Adult ; Aged ; Electric Power Supplies ; Electrodes ; Equipment Design ; Esthetics ; Evaluation Studies as Topic ; Fractals ; Humans ; Middle Aged ; Solar Energy ; Sunlight ; Surveys and Questionnaires/statistics & numerical data ; Visual Perception ; Young Adult
Language	English
Publishing date	2020-03-10
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	1932-6203
ISSN (online)	1932-6203
DOI	10.1371/journal.pone.0229945
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Article ; Online: Improved neurocognitive performance in FIV infected cats following treatment with the p75 neurotrophin receptor ligand LM11A-31.

Fogle, Jonathan E / Hudson, Lola / Thomson, Andrea / Sherman, Barbara / Gruen, Margaret / Lacelles, B Duncan / Colby, Brenda M / Clary, Gillian / Longo, Frank / Meeker, Rick B

Journal of neurovirology

2021 Volume 27, Issue 2, Page(s) 302–324

Abstract: HIV rapidly infects the central nervous system (CNS) and establishes a persistent viral reservoir within microglia, perivascular macrophages and astrocytes. Inefficient control of CNS viral replication by antiretroviral therapy results in chronic ... ...

Abstract	HIV rapidly infects the central nervous system (CNS) and establishes a persistent viral reservoir within microglia, perivascular macrophages and astrocytes. Inefficient control of CNS viral replication by antiretroviral therapy results in chronic inflammation and progressive cognitive decline in up to 50% of infected individuals with no effective treatment options. Neurotrophin based therapies have excellent potential to stabilize and repair the nervous system. A novel non-peptide ligand, LM11A-31, that targets the p75 neurotrophin receptor (p75
MeSH term(s)	Animals ; Cats ; Cognition Disorders/virology ; Feline Acquired Immunodeficiency Syndrome/complications ; Immunodeficiency Virus, Feline ; Isoleucine/analogs & derivatives ; Isoleucine/pharmacology ; Morpholines/pharmacology ; Neuroprotective Agents/pharmacology ; Receptor, Nerve Growth Factor/agonists
Chemical Substances	LM11A-31 ; Morpholines ; Neuroprotective Agents ; Receptor, Nerve Growth Factor ; Isoleucine (04Y7590D77)
Language	English
Publishing date	2021-03-04
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	1283265-0
ISSN	1538-2443 ; 1355-0284
ISSN (online)	1538-2443
ISSN	1355-0284
DOI	10.1007/s13365-021-00956-2
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Article ; Online: A Novel Transgenic Mouse Model to Investigate the Cell-Autonomous Effects of torsinA(ΔE) Expression in Striatal Output Neurons.

Gonzalez-Alegre, Pedro / Beauvais, Genevieve / Martin, Janine / Koch, Rick J / Walker, Ruth H / Patel, Jyoti C / Rice, Margaret E / Ehrlich, Michelle E

Neuroscience

2019 Volume 422, Page(s) 1–11

Abstract: Dystonia is a disabling neurological syndrome characterized by abnormal movements and postures that result from intermittent or sustained involuntary muscle contractions; mutations of DYT1/TOR1A are the most common cause of childhood-onset, generalized, ... ...

Abstract	Dystonia is a disabling neurological syndrome characterized by abnormal movements and postures that result from intermittent or sustained involuntary muscle contractions; mutations of DYT1/TOR1A are the most common cause of childhood-onset, generalized, inherited dystonia. Patient and mouse model data strongly support dysregulation of the nigrostriatal dopamine neurotransmission circuit in the presence of the DYT1-causing mutation. To determine striatal medium spiny neuron (MSN) cell-autonomous and non-cell autonomous effects relevant to dopamine transmission, we created a transgenic mouse in which expression of mutant torsinA in forebrain is restricted to MSNs. We assayed electrically evoked and cocaine-enhanced dopamine release and locomotor activity, dopamine uptake, gene expression of dopamine-associated neuropeptides and receptors, and response to the muscarinic cholinergic antagonist, trihexyphenidyl. We found that over-expression of mutant torsinA in MSNs produces complex cell-autonomous and non-cell autonomous alterations in nigrostriatal dopaminergic and intrastriatal cholinergic function, similar to that found in pan-cellular DYT1 mouse models. These data introduce targets for future studies to identify which are causative and which are compensatory in DYT1 dystonia, and thereby aid in defining appropriate therapies.
MeSH term(s)	Animals ; Cocaine/pharmacology ; Corpus Striatum/metabolism ; Disease Models, Animal ; Dopamine/metabolism ; Dystonia/genetics ; Dystonia/metabolism ; Electric Stimulation ; Female ; Gene Expression/drug effects ; Male ; Mice ; Mice, Transgenic ; Molecular Chaperones/biosynthesis ; Molecular Chaperones/genetics ; Molecular Chaperones/physiology ; Motor Skills/physiology ; Mutation ; Neural Pathways/metabolism ; Neurons/metabolism ; Substantia Nigra/metabolism ; Trihexyphenidyl/antagonists & inhibitors ; Trihexyphenidyl/pharmacology
Chemical Substances	Molecular Chaperones ; TOR1A protein, human ; Trihexyphenidyl (6RC5V8B7PO) ; Cocaine (I5Y540LHVR) ; Dopamine (VTD58H1Z2X)
Language	English
Publishing date	2019-10-26
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	196739-3
ISSN	1873-7544 ; 0306-4522
ISSN (online)	1873-7544
ISSN	0306-4522
DOI	10.1016/j.neuroscience.2019.09.007
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Zs.A 1215: Show issues

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Article ; Online: Enrichment Preferences of FIV-Infected and Uninfected Laboratory-Housed Cats.

Kennedy, Claudia J / Thomson, Andrea E / Griffith, Emily H / Fogle, Jonathan / Lascelles, B Duncan X / Meeker, Rick B / Sherman, Barbara L / Gruen, Margaret E

Viruses

2018 Volume 10, Issue 7

Abstract: Environmental enrichment is critical for alleviating stress in laboratory felines. However, there is a paucity of information about suitable enrichment for cats. This study aimed to determine preferred enrichment options of individually-housed, castrated ...

Abstract	Environmental enrichment is critical for alleviating stress in laboratory felines. However, there is a paucity of information about suitable enrichment for cats. This study aimed to determine preferred enrichment options of individually-housed, castrated male domestic short hair cats (
MeSH term(s)	Animals ; Animals, Laboratory ; Cats ; Feline Acquired Immunodeficiency Syndrome/virology ; Immunodeficiency Virus, Feline/physiology
Language	English
Publishing date	2018-07-03
Publishing country	Switzerland
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	2516098-9
ISSN	1999-4915 ; 1999-4915
ISSN (online)	1999-4915
ISSN	1999-4915
DOI	10.3390/v10070353
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Article ; Online: Fractal solar panels

Ellis T Roe / Alexander J Bies / Rick D Montgomery / William J Watterson / Blake Parris / Cooper R Boydston / Margaret E Sereno / Richard P Taylor

PLoS ONE, Vol 15, Iss 3, p e

Optimizing aesthetic and electrical performances.

2020 Volume 0229945

Abstract	Solar energy technologies have been plagued by their limited visual appeal. Because the electrical power generated by solar panels increases with their surface area and therefore their occupancy of the observer's visual field, aesthetics will play an increasingly critical role in their future success in urban environments. Inspired by previous psychology research highlighting the aesthetic qualities of fractal patterns, we investigated panel designs featuring fractal electrodes. We conducted behavioral studies which compared observers' preferences for fractal and conventional bus-bar electrode patterns, along with computer simulations which compared their electrical performances. This led us to develop a hybrid electrode pattern which best combines the fractal and bus-bar designs. Here we show that the new hybrid electrode matches the electrical performance of bus-bars in terms of light transmission and minimizing electrical power losses, while benefiting from the superior aesthetics of fractal patterns. This innovative integration of psychology and engineering studies provides a framework for developing novel electrode patterns with increased implementation and acceptance.
Keywords	Medicine ; R ; Science ; Q
Subject code	620
Language	English
Publishing date	2020-01-01T00:00:00Z
Publisher	Public Library of Science (PLoS)
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Construction of a Framework Genetic Linkage Map in Gleditsia triacanthos L

Gailing, Oliver / Margaret E. Staton / Thomas Lane / Scott E. Schlarbaum / Rick Nipper / Sandra A. Owusu / John E. Carlson

Plant molecular biology reporter. 2017 Apr., v. 35, no. 2

2017

Abstract: Genomic resources are sparse in most ecologically and economically important North American hardwood species. As part of the Hardwood Genomics project (http://www.hardwoodgenomics.org/), we evaluated the utility of restriction site associated DNA ... ...

Abstract	Genomic resources are sparse in most ecologically and economically important North American hardwood species. As part of the Hardwood Genomics project (http://www.hardwoodgenomics.org/), we evaluated the utility of restriction site associated DNA sequencing (RAD-Seq) for framework genetic linkage map construction in honeylocust (Gleditsia triacanthos L.), a leguminous tree common in eastern North America. Starting with a large open-pollinated family of progeny from a single tree, a mapping pedigree of 92 putative full-sibs was identified by kin group assignment and paternity analyses with microsatellite markers. RAD-Seq using Illumina next-generation DNA sequencing (NGS) generated over 117Â M reads among the 92 plants. De novo reference genome clustering and alignment of samples to the reference genome revealed 5849 candidate single nucleotide polymorphisms (SNPs), of which 1570 were retained after quality filtering. Of the 1570 SNPs, 236 were in pseudo-testcross mapping configuration in the maternal parent and segregated approximately in the expected 1:1 ratio. The final map generated has a total length of 815.57Â cM and consists of 178 markers on 14 linkage groups, corresponding to the haploid chromosome number in honey locust. Synteny and collinearity between honey locust and model legumes Glycine max, Medicago truncatula, and Phaseolus vulgaris were found for six of the honey locust linkage groups. RAD-Seq proved to be useful for framework linkage map construction in honey locust, a species for which no genomic resources had previously been available. However, greater sequence coverage and larger full-sib mapping pedigrees are necessary for the development of high-density linkage maps with future applications in quantitative trait locus (QTL) mapping.
Keywords	Gleditsia triacanthos ; Glycine max ; Medicago truncatula ; Phaseolus vulgaris ; chromosome mapping ; chromosome number ; genetic markers ; genome ; genomics ; haploidy ; hardwood ; legumes ; linkage groups ; models ; open pollination ; paternity ; pedigree ; progeny ; quantitative trait loci ; sequence analysis ; single nucleotide polymorphism ; trees ; North America
Language	English
Dates of publication	2017-04
Size	p. 177-187.
Publishing place	Springer US
Document type	Article
ZDB-ID	2018592-3
ISSN	1572-9818 ; 0735-9640
ISSN (online)	1572-9818
ISSN	0735-9640
DOI	10.1007/s11105-016-1012-0
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Reward-enhancing effects of d-amphetamine and its interactions with nicotine were greater in female rats and persisted across schedules of reinforcement.

McNealy, Kathleen R / Ramsay, Margaret E / Barrett, Scott T / Bevins, Rick A

Behavioural pharmacology

2021 Volume 32, Issue 5, Page(s) 435–447

Abstract: Nicotine enhances the value of environmental stimuli and rewards, and reward enhancement can maintain nicotine consumption. Stimulants such as d-amphetamine are misused more by women and are commonly co-used with nicotine. d-Amphetamine potentiates ... ...

Abstract	Nicotine enhances the value of environmental stimuli and rewards, and reward enhancement can maintain nicotine consumption. Stimulants such as d-amphetamine are misused more by women and are commonly co-used with nicotine. d-Amphetamine potentiates nicotine's effects in human and animal research. To date, there are no published studies examining this interaction in a reward-enhancement task. The current study sought to investigate the reward-enhancing effects of nicotine alongside and coadministered with d-amphetamine. Further, we evaluated the persistence of reward enhancement across ratio and temporal schedules of reinforcement. We used 10 male and 10 female Sprague-Dawley rats. Enhancement was assessed within subjects by examining active lever pressing for a visual stimulus reinforcer on variable ratio 3, variable interval 30 s and variable time 30 s - variable ratio 3 schedules. Before 1-h sessions, rats received one injection of saline, 0.1 or 0.3 mg/kg d-amphetamine and one of saline or 0.4 mg/kg nicotine, making six possible drug combinations (saline + saline, saline + nicotine, 0.1 d-amphetamine + aline, 0.1 d-amphetamine + nicotine, 0.3 d-amphetamine + saline and 0.3 d-amphetamine + nicotine) experienced in a randomized order by each rat. When d-amphetamine was coadministered with nicotine, we found an interaction effect on reward enhancement that persisted across schedules of reinforcement. Males and females exhibited reward enhancement by 0.3 d-amphetamine, while only females showed reward enhancement by 0.1 d-amphetamine. Further, females responded more for the visual stimulus than males in all d-amphetamine conditions. Future studies should assess how reward enhancement is involved in high nicotine-amphetamine comorbidity rates and enhanced amphetamine misuse in women.
MeSH term(s)	Amphetamine-Related Disorders/epidemiology ; Animals ; Behavior, Animal/drug effects ; Central Nervous System Stimulants/pharmacology ; Comorbidity ; Dextroamphetamine/pharmacology ; Drug Synergism ; Female ; Humans ; Male ; Nicotine/pharmacology ; Photic Stimulation/methods ; Rats ; Rats, Sprague-Dawley ; Reinforcement, Psychology ; Reward ; Sex Factors ; Tobacco Use Disorder/epidemiology
Chemical Substances	Central Nervous System Stimulants ; Nicotine (6M3C89ZY6R) ; Dextroamphetamine (TZ47U051FI)
Language	English
Publishing date	2021-05-19
Publishing country	England
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	1027374-8
ISSN	1473-5849 ; 0955-8810
ISSN (online)	1473-5849
ISSN	0955-8810
DOI	10.1097/FBP.0000000000000637
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Zs.A 2883: Show issues

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Article: Combination therapy with rFVIIa and platelets for hemorrhage in patients with severe thrombocytopenia and alloimmunization.

Savani, Bipin N / Dunbar, Cynthia E / Rick, Margaret E

American journal of hematology

2006 Volume 81, Issue 3, Page(s) 218–219

MeSH term(s)	Adult ; Anemia, Aplastic/complications ; Anemia, Aplastic/immunology ; Anemia, Aplastic/therapy ; Blood Group Incompatibility/etiology ; Blood Group Incompatibility/immunology ; Blood Platelets/immunology ; Factor VII/administration & dosage ; Factor VIIa ; Hemorrhage/drug therapy ; Hemorrhage/etiology ; Hemorrhage/immunology ; Humans ; Male ; Middle Aged ; Platelet Transfusion/adverse effects ; Platelet Transfusion/methods ; Purpura, Thrombocytopenic, Idiopathic/etiology ; Purpura, Thrombocytopenic, Idiopathic/immunology ; Recombinant Proteins/administration & dosage
Chemical Substances	Recombinant Proteins ; Factor VII (9001-25-6) ; recombinant FVIIa (AC71R787OV) ; Factor VIIa (EC 3.4.21.21)
Language	English
Publishing date	2006-03
Publishing country	United States
Document type	Case Reports ; Letter
ZDB-ID	196767-8
ISSN	1096-8652 ; 0361-8609
ISSN (online)	1096-8652
ISSN	0361-8609
DOI	10.1002/ajh.20506
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Zs.A 1251: Show issues

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