LIVIVO - Search results -

Search results

Result 1 - 10 of total 1027

Search options

Article ; Online: An imidazole based H-Phe-Phe-NH

Skogh, Anna / Lesniak, Anna / Sköld, Christian / Karlgren, Maria / Gaugaz, Fabienne Z / Svensson, Richard / Diwakarla, Shanti / Jonsson, Anna / Fransson, Rebecca / Nyberg, Fred / Hallberg, Mathias / Sandström, Anja

Bioorganic & medicinal chemistry letters

2018 Volume 28, Issue 14, Page(s) 2446–2450

Abstract: The dipeptide amide H-Phe-Phe-NH ...

Abstract	The dipeptide amide H-Phe-Phe-NH
MeSH term(s)	Amides/blood ; Amides/chemistry ; Amides/pharmacology ; Animals ; Cell Death/drug effects ; Cell Survival/drug effects ; Cells, Cultured ; Dipeptides/blood ; Dipeptides/chemistry ; Dipeptides/pharmacology ; Dose-Response Relationship, Drug ; Hyperalgesia/drug therapy ; Imidazoles/blood ; Imidazoles/chemistry ; Imidazoles/pharmacology ; Injections, Intraperitoneal ; Mice ; Molecular Structure ; Peptidomimetics/blood ; Peptidomimetics/chemistry ; Peptidomimetics/pharmacology ; Rats ; Spinal Nerves/drug effects ; Spinal Nerves/injuries
Chemical Substances	Amides ; Dipeptides ; Imidazoles ; Peptidomimetics
Language	English
Publishing date	2018-06-15
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1063195-1
ISSN	1464-3405 ; 0960-894X
ISSN (online)	1464-3405
ISSN	0960-894X
DOI	10.1016/j.bmcl.2018.06.009
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 3203: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Discovery of 3-Cyano- N-(3-(1-isobutyrylpiperidin-4-yl)-1-methyl-4-(trifluoromethyl)-1 H-pyrrolo[2,3- b]pyridin-5-yl)benzamide: A Potent, Selective, and Orally Bioavailable Retinoic Acid Receptor-Related Orphan Receptor C2 Inverse Agonist.

Schnute, Mark E / Wennerstål, Mattias / Alley, Jennifer / Bengtsson, Martin / Blinn, James R / Bolten, Charles W / Braden, Timothy / Bonn, Tomas / Carlsson, Bo / Caspers, Nicole / Chen, Ming / Choi, Chulho / Collis, Leon P / Crouse, Kimberly / Färnegårdh, Mathias / Fennell, Kimberly F / Fish, Susan / Flick, Andrew C / Goos-Nilsson, Annika /

Gullberg, Hjalmar / Harris, Peter K / Heasley, Steven E / Hegen, Martin / Hromockyj, Alexander E / Hu, Xiao / Husman, Bolette / Janosik, Tomasz / Jones, Peter / Kaila, Neelu / Kallin, Elisabet / Kauppi, Björn / Kiefer, James R / Knafels, John / Koehler, Konrad / Kruger, Lars / Kurumbail, Ravi G / Kyne, Robert E / Li, Wei / Löfstedt, Joakim / Long, Scott A / Menard, Carol A / Mente, Scot / Messing, Dean / Meyers, Marvin J / Napierata, Lee / Nöteberg, Daniel / Nuhant, Philippe / Pelc, Matthew J / Prinsen, Michael J / Rhönnstad, Patrik / Backström-Rydin, Eva / Sandberg, Johnny / Sandström, Maria / Shah, Falgun / Sjöberg, Maria / Sundell, Aron / Taylor, Alexandria P / Thorarensen, Atli / Trujillo, John I / Trzupek, John D / Unwalla, Ray / Vajdos, Felix F / Weinberg, Robin A / Wood, David C / Xing, Li / Zamaratski, Edouard / Zapf, Christoph W / Zhao, Yajuan / Wilhelmsson, Anna / Berstein, Gabriel

Journal of medicinal chemistry

2018 Volume 61, Issue 23, Page(s) 10415–10439

Abstract: ... trifluoromethyl)-1 H-pyrrolo[2,3- b]pyridin-5-yl)benzamide as a potent and selective RORC2 inverse agonist ...

Abstract	The nuclear hormone receptor retinoic acid receptor-related orphan C2 (RORC2, also known as RORγt) is a promising target for the treatment of autoimmune diseases. A small molecule, inverse agonist of the receptor is anticipated to reduce production of IL-17, a key proinflammatory cytokine. Through a high-throughput screening approach, we identified a molecule displaying promising binding affinity for RORC2, inhibition of IL-17 production in Th17 cells, and selectivity against the related RORA and RORB receptor isoforms. Lead optimization to improve the potency and metabolic stability of this hit focused on two key design strategies, namely, iterative optimization driven by increasing lipophilic efficiency and structure-guided conformational restriction to achieve optimal ground state energetics and maximize receptor residence time. This approach successfully identified 3-cyano- N-(3-(1-isobutyrylpiperidin-4-yl)-1-methyl-4-(trifluoromethyl)-1 H-pyrrolo[2,3- b]pyridin-5-yl)benzamide as a potent and selective RORC2 inverse agonist, demonstrating good metabolic stability, oral bioavailability, and the ability to reduce IL-17 levels and skin inflammation in a preclinical in vivo animal model upon oral administration.
MeSH term(s)	Administration, Oral ; Animals ; Biological Availability ; Drug Design ; Drug Evaluation, Preclinical ; Drug Inverse Agonism ; Humans ; Mice ; Nuclear Receptor Subfamily 1, Group F, Member 3/agonists ; Pyridines/administration & dosage ; Pyridines/pharmacokinetics ; Pyridines/pharmacology ; Th17 Cells/drug effects ; Th17 Cells/metabolism
Chemical Substances	Nuclear Receptor Subfamily 1, Group F, Member 3 ; Pyridines
Language	English
Publishing date	2018-09-09
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	218133-2
ISSN	1520-4804 ; 0022-2623
ISSN (online)	1520-4804
ISSN	0022-2623
DOI	10.1021/acs.jmedchem.8b00392
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.B 151: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
Zs.MB 1: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Mechanistic investigations of anaerobic sulfatase-maturating enzyme: direct Cbeta H-atom abstraction catalyzed by a radical AdoMet enzyme.

Benjdia, Alhosna / Leprince, Jérôme / Sandström, Corine / Vaudry, Hubert / Berteau, Olivier

Journal of the American Chemical Society

2009 Volume 131, Issue 24, Page(s) 8348–8349

Abstract: ... deoxyadenosyl radical to catalyze direct H-atom abstraction from the substrate. We thus established that anSMEs ... are the first radical AdoMet enzymes catalyzing a post-translational modification involving C(beta) H ...

Abstract	Sulfatases are unique in requiring an essential post-translational modification of a critical active-site cysteinyl or seryl residue to 3-oxoalanine usually called C alpha-formylglycine (FGly). This post-translational modification is catalyzed anaerobically by anaerobic Sulfatase Maturating Enzyme (anSME), a member of the radical AdoMet superfamily. Using a new labeled substrate, we demonstrate that anSME uses a 5'-deoxyadenosyl radical to catalyze direct H-atom abstraction from the substrate. We thus established that anSMEs are the first radical AdoMet enzymes catalyzing a post-translational modification involving C(beta) H-atom abstraction from an active site cysteinyl or seryl residue. This mechanistic study allowed us to decipher the first steps of the mechanism of this new radical AdoMet enzyme family.
MeSH term(s)	Alanine/analogs & derivatives ; Alanine/chemistry ; Alanine/metabolism ; Anaerobiosis ; Catalysis ; Clostridium perfringens/enzymology ; Deoxyadenosines/chemistry ; Deoxyadenosines/metabolism ; Glycine/analogs & derivatives ; Glycine/chemistry ; Glycine/metabolism ; Hydrogen/chemistry ; Hydrogen/metabolism ; Nuclear Magnetic Resonance, Biomolecular ; S-Adenosylmethionine/chemistry ; S-Adenosylmethionine/metabolism ; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization ; Sulfatases/chemistry ; Sulfatases/metabolism
Chemical Substances	Deoxyadenosines ; 5'-deoxyadenosine (4754-39-6) ; C(alpha)-formylglycine (5735-66-0) ; S-Adenosylmethionine (7LP2MPO46S) ; Hydrogen (7YNJ3PO35Z) ; Sulfatases (EC 3.1.6.-) ; Alanine (OF5P57N2ZX) ; Glycine (TE7660XO1C)
Language	English
Publishing date	2009-06-24
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	3155-0
ISSN	1520-5126 ; 0002-7863
ISSN (online)	1520-5126
ISSN	0002-7863
DOI	10.1021/ja901571p
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Bonn / Germany

Z 4' 55/32: Show issues
Z 7.3: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Aminocarbonylation of 4-iodo-1H-imidazoles with an amino acid amide nucleophile: synthesis of constrained H-Phe-Phe-NH2 analogues.

Skogh, Anna / Fransson, Rebecca / Sköld, Christian / Larhed, Mats / Sandström, Anja

The Journal of organic chemistry

2013 Volume 78, Issue 23, Page(s) 12251–12256

Abstract: ... exemplified by the synthesis of constrained H-Phe-Phe-NH2 analogues. ...

Abstract	A simple and an expedient process to prepare 5-aryl-1-benzyl-1H-imidazole-4-carboxamides by the aminocarbonylation of 5-aryl-4-iodo-1H-imidazoles using ex situ generation of CO from Mo(CO)6 with an amino acid amide nucleophile is reported. Furthermore, a microwave-assisted protocol for the direct C-5 arylation of 1-benzyl-1H-imidazole and a regioselective C-4 iodination method to acquire starting material for our aminocarbonylation are presented. The method can be used to prepare imidazole based peptidomimetics, herein exemplified by the synthesis of constrained H-Phe-Phe-NH2 analogues.
MeSH term(s)	Amides/chemistry ; Amino Acids/chemistry ; Imidazoles/chemistry ; Molecular Structure ; Peptide Fragments/chemical synthesis ; Peptide Fragments/chemistry
Chemical Substances	Amides ; Amino Acids ; Imidazoles ; Peptide Fragments
Language	English
Publishing date	2013-12-06
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	123490-0
ISSN	1520-6904 ; 0022-3263
ISSN (online)	1520-6904
ISSN	0022-3263
DOI	10.1021/jo4020613
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 4473: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Crossroads at the Origin of Prebiotic Chemical Complexity: Hydrogen Cyanide Product Diversification.

Sandström, Hilda / Rahm, Martin

The journal of physical chemistry. A

2023 Volume 127, Issue 20, Page(s) 4503–4510

Abstract: Products of hydrogen cyanide (HCN) reactivity are suspected to play important roles in astrochemistry and, possibly, the origin of life. The composition, chemical structure, and mechanistic details for formation of products from HCN's self-reactions have, ...

Abstract	Products of hydrogen cyanide (HCN) reactivity are suspected to play important roles in astrochemistry and, possibly, the origin of life. The composition, chemical structure, and mechanistic details for formation of products from HCN's self-reactions have, however, proven elusive for decades. Here, we elucidate base-catalyzed reaction mechanisms for the formation of diaminomaleonitrile and polyimine in liquid HCN using ab initio molecular dynamics simulations. Both materials are proposed as key intermediates for driving further chemical evolution. The formation of these materials is predicted to proceed at similar rates, thereby offering an explanation of how HCN's self-reactions can diversify quickly under kinetic control. Knowledge of these reaction routes provides a basis for rationalizing subsequent reactivity in astrochemical environments such as on Saturn's moon Titan, in the subsurface of comets, in exoplanet atmospheres, and on the early Earth.
Language	English
Publishing date	2023-05-11
Publishing country	United States
Document type	Journal Article
ISSN	1520-5215
ISSN (online)	1520-5215
DOI	10.1021/acs.jpca.3c01504
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article: Latency of Plasma Membrane H-ATPase in Vesicles Isolated by Aqueous Phase Partitioning : Increased substrate Accessibility or Enzyme Activation.

Sandstrom, R P / Deboer, A H / Lomax, T L / Cleland, R E

Plant physiology

2006 Volume 85, Issue 3, Page(s) 693–698

Abstract: The properties of the plasma membrane H(+)-ATPase and the cause of its latency have been studied ...

Abstract	The properties of the plasma membrane H(+)-ATPase and the cause of its latency have been studied using a highly purified plasma membrane fraction from oat (Avena sativa L., cv Victory) roots, prepared by aqueous two-phase partitioning. The ATPase has a maximum specific activity (at 37 degrees C) in excess of 4 micromoles inorganic phosphate per milligram protein per minute in the presence of nondenaturing surfactants. It is inhibited by more than 90% by vanadate, is specific for ATP, has a pH optimum of 6.5, and is stimulated more than 4-fold by 50 millimolar K(+) in the presence of low levels of the nondenaturing surfactants Triton X-100 and lysolecithin. This ;latent' activity is usually explained as being a result of the inability of ATP to reach the ATPase in right-side out, sealed vesicles, until they are disrupted by surfactants. Consistent with this idea, trypsin digestion significantly inhibited the ATPase only in the presence of the surfactants. Electron spin resonance spectroscopy volume measurements confirmed that surfactant-free vesicles were mostly sealed to molecules similar to ATP. However, the Triton to protein ratio required to disrupt vesicle integrity completely is 10-fold less than that needed to promote maximum ATPase activity. We propose that plasma membrane ATPase activation is due not solely to vesicle disruption and accessibility of ATP to the ATPase but to the surfactants activating the ATPase by altering the lipid environment in its vicinity or by removing an inhibitory subunit.
Language	English
Publishing date	2006-04-28
Publishing country	United States
Document type	Journal Article
ZDB-ID	208914-2
ISSN	1532-2548 ; 0032-0889
ISSN (online)	1532-2548
ISSN	0032-0889
DOI	10.1104/pp.85.3.693
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Bonn / Germany

Z 1193: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Article: The role of trade in the greenhouse gas footprints of EU diets

Sandström, Vilma / Valin, Hugo / Krisztin, Tamás / Havlík, Petr / Kastner, Thomas

Global food security, 19:48-55

2018

Abstract: International trade presents a challenge for measuring the greenhouse gas (GHG) emission footprint of human diets, because imported food is produced with different production efficiencies and sourcing regions differ in land use histories. We analyze how ... ...

Institution	Senckenberg Biodiversität und Klima Forschungszentrum
Abstract	International trade presents a challenge for measuring the greenhouse gas (GHG) emission footprint of human diets, because imported food is produced with different production efficiencies and sourcing regions differ in land use histories. We analyze how trade and countries of origin impact GHG footprint calculation for EU food consumption. We find that food consumption footprints can differ considerably between the EU countries with estimates varying from 610 to 1460 CO2-eq. cap−1 yr−1. These estimates include the GHG emissions from primary production, international trade and land use change. The share of animal products in the diet is the most important factor determining the footprint of food consumption. Embedded land use change in imports also plays a major role. Transition towards more plant-based diets has a great potential for climate change mitigation.
Keywords	Climate change ; Greenhouse gas emissions accounting ; Food consumption ; International trade ; Land use change
Language	English
Document type	Article
Database	Repository for Life Sciences

Full text online

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Constrained H-Phe-Phe-NH2 analogues with high affinity to the substance P 1-7 binding site and with improved metabolic stability and cell permeability.

Fransson, Rebecca / Sköld, Christian / Kratz, Jadel M / Svensson, Richard / Artursson, Per / Nyberg, Fred / Hallberg, Mathias / Sandström, Anja

Journal of medicinal chemistry

2013 Volume 56, Issue 12, Page(s) 4953–4965

Abstract: We recently reported the discovery of H-Phe-Phe-NH2 as a small and high affinity ligand ... for the substance P 1-7 (SP(1-7), H-Arg-Pro-Lys-Pro-Gln-Gln-Phe-OH) specific binding site and its intriguing ability ... of modified H-Phe-Phe-NH2 analogues is presented together with their potential active uptake by PEPT1 ...

Abstract	We recently reported the discovery of H-Phe-Phe-NH2 as a small and high affinity ligand for the substance P 1-7 (SP(1-7), H-Arg-Pro-Lys-Pro-Gln-Gln-Phe-OH) specific binding site and its intriguing ability to reduce neuropathic pain. With the overall aim to develop stable and orally bioavailable SP(1-7) mimetics, the dipeptide was chosen as a lead compound. Herein the structure-activity relationship (SAR) of a set of modified H-Phe-Phe-NH2 analogues is presented together with their potential active uptake by PEPT1 transporter, intestinal permeability, and metabolic stability. Local constraints via peptide backbone methylation or preparation of cyclized analogues based on pyrrolidine were evaluated and were shown to significantly improve the in vitro pharmacokinetic properties. The SAR was rationalized by deriving a plausible binding pose for the high affinity ligands. Rigidification using a 3-phenylpyrrolidine moiety in the C-terminal of H-Phe-Phe-NH2 resulted in high affinity and improved intrinsic clearance and intestinal epithelial permeability.
MeSH term(s)	Binding Sites ; Dipeptides/chemistry ; Dipeptides/metabolism ; Drug Stability ; Humans ; Models, Molecular ; Peptide Fragments/chemistry ; Peptide Fragments/metabolism ; Permeability ; Protein Binding ; Protein Conformation ; Substance P/chemistry ; Substance P/metabolism
Chemical Substances	Dipeptides ; Peptide Fragments ; phenylalanylphenylalanine (2577-40-4) ; Substance P (33507-63-0) ; substance P (1-7) (72226-88-1)
Language	English
Publishing date	2013-06-27
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	218133-2
ISSN	1520-4804 ; 0022-2623
ISSN (online)	1520-4804
ISSN	0022-2623
DOI	10.1021/jm400209h
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.B 151: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
Zs.MB 1: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Role of patient characteristics in adherence to first-line treatment guidelines in breast, lung and prostate cancer: insights from the Nordic healthcare system.

Sandström, Niclas / Leppälä, Emilia / Jekunen, Antti / Johansson, Mikael / Andersén, Heidi

BMJ open

2024 Volume 14, Issue 4, Page(s) e084689

Abstract: Objectives: This study investigates the influence of socioeconomic status, health literacy, and numeracy on treatment decisions and the occurrence of adverse events in patients with breast, lung, and prostate cancer within a Nordic healthcare setting.!## ...

Abstract	Objectives: This study investigates the influence of socioeconomic status, health literacy, and numeracy on treatment decisions and the occurrence of adverse events in patients with breast, lung, and prostate cancer within a Nordic healthcare setting. Design: A follow-up to a cross-sectional, mixed-methods, single-centre study. Setting: A Nordic, tertiary cancer clinic. Participants: A total of 244 participants with breast, lung and prostate cancer were initially identified, of which 138 first-line treatment participants were eligible for this study. First-line treatment participants (n=138) surpassed the expected cases (n=108). Interventions: Not applicable as this was an observational study. Primary and secondary outcome measures: The study's primary endpoint was the rate of guideline adherence. The secondary endpoint involved assessing treatment toxicity in the form of adverse events. Results: Guideline-adherent treatment was observed in 114 (82.6%) cases. First-line treatment selection appeared uninfluenced by participants' education, occupation, income or self-reported health literacy. A minority (3.6%) experienced difficulties following treatment instructions, primarily with oral cancer medications. Conclusions: The findings indicated lesser cancer health disparities regarding guideline adherence and treatment toxicity within the Nordic healthcare framework. A causal connection may not be established; however, the findings contribute to discourse on equitable cancer health provision.
MeSH term(s)	Humans ; Male ; Cross-Sectional Studies ; Delivery of Health Care ; Lung ; Occupations ; Prostatic Neoplasms/therapy ; Female
Language	English
Publishing date	2024-04-08
Publishing country	England
Document type	Observational Study ; Journal Article
ZDB-ID	2599832-8
ISSN	2044-6055 ; 2044-6055
ISSN (online)	2044-6055
ISSN	2044-6055
DOI	10.1136/bmjopen-2024-084689
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Socioeconomic status and lifestyle patterns in the most common cancer types-community-based research.

Sandström, Niclas / Johansson, Mikael / Jekunen, Antti / Andersén, Heidi

BMC public health

2023 Volume 23, Issue 1, Page(s) 1722

Abstract: Introduction: As the global burden of chronic cancer increases, its correlation to lifestyle, socioeconomic status (SES) and health equity becomes more important. The aim of the present study was to provide a snapshot of the socioeconomic and lifestyle ... ...

Abstract	Introduction: As the global burden of chronic cancer increases, its correlation to lifestyle, socioeconomic status (SES) and health equity becomes more important. The aim of the present study was to provide a snapshot of the socioeconomic and lifestyle patterns for different cancer types in patients at a Nordic tertiary cancer clinic. Materials and methods: In a descriptive observational study, questionnaires addressed highest-attained educational level, occupational level, economy, relationship status, exposures, and lifestyle habits. The questionnaire was distributed to all cancer patients attending the cancer clinic. Treating physicians added further information about the cancer disease, including primary origin, pathology report, TNM-classification and stage. Results: Patients with lung cancer had the lowest SES, and patients with gastrointestinal (GI) cancer, other cancer types and prostate cancer had the second, third and fourth lowest SES, respectively. However, breast cancer patients had the highest SES. Lifestyle and exposure patterns differed among the major cancer types. Lung cancer patients reported the highest proportion of unfavourable lifestyle and exposure patterns, and patients with GI cancer, prostate cancer and other cancer types had the second, third and fourth highest proportion of unfavourable lifestyle and exposure patterns, respectively. The most favourable exposure and lifestyle patterns were observed in breast cancer patients. Conclusions: The present study indicated significant socioeconomic and lifestyle differences among cancer types at a Nordic cancer centre, with differences in lifestyle being more prominent than socioeconomic differences.
MeSH term(s)	Male ; Humans ; Prostatic Neoplasms ; Breast Neoplasms ; Lung Neoplasms ; Social Class ; Life Style
Language	English
Publishing date	2023-09-05
Publishing country	England
Document type	Observational Study ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2041338-5
ISSN	1471-2458 ; 1471-2458
ISSN (online)	1471-2458
ISSN	1471-2458
DOI	10.1186/s12889-023-16677-6
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

To top

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito