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  1. Article ; Online: Treatment-Resistant Depression (TRD): Management Approaches in a Rapidly Evolving Therapeutic Landscape.

    Jha, Manish Kumar / Trivedi, Madhukar H

    The Psychiatric clinics of North America

    2023  Volume 46, Issue 2, Page(s) xiii–xiv

    MeSH term(s) Humans ; Depression ; Antidepressive Agents/therapeutic use ; Depressive Disorder, Treatment-Resistant/drug therapy
    Chemical Substances Antidepressive Agents
    Language English
    Publishing date 2023-03-10
    Publishing country United States
    Document type Editorial
    ZDB-ID 431518-2
    ISSN 1558-3147 ; 0193-953X
    ISSN (online) 1558-3147
    ISSN 0193-953X
    DOI 10.1016/j.psc.2023.03.014
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  2. Article ; Online: Major Depressive Disorder in Primary Care: Strategies for Identification.

    Trivedi, Madhukar H

    The Journal of clinical psychiatry

    2020  Volume 81, Issue 2

    Abstract: Depression is one of the most common mental disorders, affecting more than 300 million people of all ages globally, and is now the leading cause of disability. Despite the availability of effective psychological and pharmacologic treatments, depression ... ...

    Abstract Depression is one of the most common mental disorders, affecting more than 300 million people of all ages globally, and is now the leading cause of disability. Despite the availability of effective psychological and pharmacologic treatments, depression recognition and treatment rates remain low. Clinicians can improve the recognition, diagnosis, and treatment of depression by using a measurement-based care approach. The systematic use of validated screening tools can improve recognition and diagnosis. The US Preventive Services Task force recommends routine screening of depression in adults and adolescents as long as systems are in place for accurate diagnosis, treatment initiation, and appropriate follow-up. Here, tools and diagnostic criteria are described.
    MeSH term(s) Adolescent ; Adult ; Child ; Comorbidity ; Depressive Disorder, Major/diagnosis ; Depressive Disorder, Major/epidemiology ; Depressive Disorder, Major/therapy ; Humans ; Primary Health Care ; Suicide
    Language English
    Publishing date 2020-03-17
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 716287-x
    ISSN 1555-2101 ; 0160-6689
    ISSN (online) 1555-2101
    ISSN 0160-6689
    DOI 10.4088/JCP.UT17042BR1C
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: How Can Measurement-Based Care Help Improve Treatment Outcomes for Major Depressive Disorder in Primary Care?

    Trivedi, Madhukar H

    The Journal of clinical psychiatry

    2020  Volume 81, Issue 2

    Abstract: Antidepressant medications and psychotherapies can help many patients with major depressive disorder (MDD), yet millions of primary care patients do not receive effective treatment. Patients with MDD often experience side effects, inadequate response, ... ...

    Abstract Antidepressant medications and psychotherapies can help many patients with major depressive disorder (MDD), yet millions of primary care patients do not receive effective treatment. Patients with MDD often experience side effects, inadequate response, and residual symptoms that interfere with functioning, all of which can lead to discontinuation. To improve patient outcomes, clinicians can implement strategies of measurement-based care to regularly assess depressive symptoms, treatment adherence, and adverse effects to make informed treatment decisions. Patient education and involvement in managing their illness can also improve outcomes.
    MeSH term(s) Adult ; Antidepressive Agents/administration & dosage ; Antidepressive Agents/adverse effects ; Antidepressive Agents/therapeutic use ; Behavior Therapy ; Depressive Disorder, Major/diagnosis ; Depressive Disorder, Major/therapy ; Electroconvulsive Therapy ; Humans ; Outcome Assessment, Health Care ; Psychiatric Status Rating Scales ; Remission Induction ; Transcranial Magnetic Stimulation
    Chemical Substances Antidepressive Agents
    Language English
    Publishing date 2020-03-17
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 716287-x
    ISSN 1555-2101 ; 0160-6689
    ISSN (online) 1555-2101
    ISSN 0160-6689
    DOI 10.4088/JCP.UT17042BR2C
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Microbes and mental health: translating preclinical findings to the clinic.

    Chin Fatt, Cherise R / Trivedi, Madhukar H

    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology

    2023  Volume 49, Issue 1, Page(s) 345–346

    MeSH term(s) Humans ; Mental Health ; Mental Disorders/therapy
    Language English
    Publishing date 2023-08-08
    Publishing country England
    Document type News
    ZDB-ID 639471-1
    ISSN 1740-634X ; 0893-133X
    ISSN (online) 1740-634X
    ISSN 0893-133X
    DOI 10.1038/s41386-023-01695-0
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  5. Article ; Online: Antisuicidal Effects of Ketamine: A Promising First Step.

    Trivedi, Madhukar H

    The American journal of psychiatry

    2018  Volume 175, Issue 2, Page(s) 97–98

    MeSH term(s) Ketamine ; Suicidal Ideation ; Suicide
    Chemical Substances Ketamine (690G0D6V8H)
    Language English
    Publishing date 2018--01
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 280045-7
    ISSN 1535-7228 ; 0002-953X
    ISSN (online) 1535-7228
    ISSN 0002-953X
    DOI 10.1176/appi.ajp.2017.17111261
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  6. Article ; Online: Identifying novel mechanisms and treatment targets for irritability and aggression in psychiatric disorders.

    Jha, Manish Kumar / Trivedi, Madhukar H

    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology

    2021  Volume 47, Issue 1, Page(s) 420–421

    MeSH term(s) Aggression/psychology ; Humans ; Irritable Mood ; Mental Disorders/drug therapy
    Language English
    Publishing date 2021-09-20
    Publishing country England
    Document type News ; Research Support, Non-U.S. Gov't
    ZDB-ID 639471-1
    ISSN 1740-634X ; 0893-133X
    ISSN (online) 1740-634X
    ISSN 0893-133X
    DOI 10.1038/s41386-021-01166-4
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  7. Article ; Online: Immune Dysregulation in Treatment-Resistant Depression: Precision Approaches to Treatment Selection and Development of Novel Treatments.

    Chin Fatt, Cherise R / Mayes, Taryn L / Trivedi, Madhukar H

    The Psychiatric clinics of North America

    2023  Volume 46, Issue 2, Page(s) 403–413

    Abstract: Owing to the link between immune dysfunction and treatment-resistant depression (TRD) and the overwhelming evidence that the immune dysregulation and major depressive disorder (MDD) are associated with each other, using immune profiles to identify the ... ...

    Abstract Owing to the link between immune dysfunction and treatment-resistant depression (TRD) and the overwhelming evidence that the immune dysregulation and major depressive disorder (MDD) are associated with each other, using immune profiles to identify the biological distinct subgroup may be the step forward to understanding MDD and TRD. This report aims to briefly review the role of inflammation in the pathophysiology of depression (and TRD in particular), the role of immune dysfunction to guide precision medicine, tools used to understand immune function, and novel statistical techniques.
    MeSH term(s) Humans ; Depressive Disorder, Major/drug therapy ; Depression ; Depressive Disorder, Treatment-Resistant/drug therapy ; Precision Medicine
    Language English
    Publishing date 2023-05-20
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 431518-2
    ISSN 1558-3147 ; 0193-953X
    ISSN (online) 1558-3147
    ISSN 0193-953X
    DOI 10.1016/j.psc.2023.02.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Correction: Depression education fotonovela for engagement of Hispanic patients in treatment: a randomized clinical trial.

    Sanchez, Katherine / Eghaneyan, Brittany H / Killian, Michael O / Cabassa, Leopoldo J / Trivedi, Madhukar H

    BMC psychiatry

    2023  Volume 23, Issue 1, Page(s) 269

    Language English
    Publishing date 2023-04-19
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2050438-X
    ISSN 1471-244X ; 1471-244X
    ISSN (online) 1471-244X
    ISSN 1471-244X
    DOI 10.1186/s12888-023-04737-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: The Individual and Societal Burden of Treatment-Resistant Depression: An Overview.

    Baig-Ward, Kimberlyn Maravet / Jha, Manish Kumar / Trivedi, Madhukar H

    The Psychiatric clinics of North America

    2023  Volume 46, Issue 2, Page(s) 211–226

    Abstract: Major depressive disorder is characterized by depressed mood and/or anhedonia with neurovegetative symptoms and neurocognitive changes affecting an individual's functioning in multiple aspects of life. Treatment outcomes with commonly used ... ...

    Abstract Major depressive disorder is characterized by depressed mood and/or anhedonia with neurovegetative symptoms and neurocognitive changes affecting an individual's functioning in multiple aspects of life. Treatment outcomes with commonly used antidepressants remain suboptimal. Treatment-resistant depression (TRD) should be considered after inadequate improvement with two or more antidepressant treatments of adequate dose and duration. TRD has been associated with increased disease burden including higher associated costs (both socially and financially) affecting both the individual and society. Additional research is needed to better understand the long-term burden of TRD to both the individual and society.
    MeSH term(s) Humans ; Depression/therapy ; Depressive Disorder, Major/drug therapy ; Antidepressive Agents/therapeutic use ; Depressive Disorder, Treatment-Resistant/drug therapy ; Treatment Outcome
    Chemical Substances Antidepressive Agents
    Language English
    Publishing date 2023-05-05
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 431518-2
    ISSN 1558-3147 ; 0193-953X
    ISSN (online) 1558-3147
    ISSN 0193-953X
    DOI 10.1016/j.psc.2023.02.001
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  10. Article ; Online: Addressing adherence to antidepressant treatment for depression.

    Mayes, Taryn L / Trivedi, Madhukar H

    Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)

    2020  Volume 43, Issue 2, Page(s) 125–126

    MeSH term(s) Antidepressive Agents/therapeutic use ; Depression/drug therapy ; Humans ; Medication Adherence
    Chemical Substances Antidepressive Agents
    Language English
    Publishing date 2020-11-13
    Publishing country Brazil
    Document type Editorial
    ISSN 1809-452X
    ISSN (online) 1809-452X
    DOI 10.1590/1516-4446-2020-0022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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